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Bevacizumab in Wet AMD treatment: A tribute to the thirteen years of experience from the beginning of the anti‑VEGF era in Romania

  • Authors:
    • Horia T. Stanca
    • Simona Stanca
    • Bogdana Tabacaru
    • Madalina Boruga
    • Florian Balta
  • View Affiliations / Copyright

    Affiliations: Department of Ophthalmology, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Pediatrics, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Pharmacy, ‘Victor Babes’ University of Medicine and Pharmacy, 300041 Timisoara, Romania
    Copyright: © Stanca et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 4993-5000
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    Published online on: August 6, 2019
       https://doi.org/10.3892/etm.2019.7858
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Abstract

This study aimed to identify and describe anatomical and functional changes on short (1‑3 months) and medium (6‑12 months) term after intravitreal injections of bevacizumab (Avastin, Genentech) in patients with choroidal neovascularization (CNV) in the context of exudative form of age‑related macular degeneration (AMD). We performed a retrospective, analytical, interventional study, based on a series of cases with exudative form of AMD, which also comprised a prospective component related to the inclusion and treatment of the patients with a very new interventional method for that time (2006) and the follow‑up of the effects of intravitreal injection of bevacizumab (1.25 mg) therapy in three monthly doses for short (1‑3 months) and medium (6‑18 months) periods of time. The follow‑up of these patients was made by determining visual acuity (VA) as best corrected visual acuity (BCVA) at baseline and at every visit, slit lamp examination with contact or noncontact lenses each time, and optical coherence tomography and/or angiofluorography, applied only for certain patients, at various times of the study. In total, 376 intravitreal injections were administered to 117 eyes of 96 patients. The VA improved in the assessment of 3 months in 77 eyes (66%), either subjective (by the patient) or objectively quantified (by the physician). In 40 eyes (34%), there was no change in VA. In patients for whom optical coherence tomography could be performed, a significant reduction of the macula's thickness was found. The use of bevacizumab in subretinal neovascular membrane treatment is effective and safe on short and medium term, with the improvement of BCVA and reduction of macular edema in a significant number of cases.
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1 

Klein R, Klein BE, Jensen SC and Meuer SM: The five-year incidence and progression of age-related maculopathy: The Beaver Dam Eye Study. Ophthalmology. 104:7–21. 1997. View Article : Google Scholar : PubMed/NCBI

2 

National Eye Institute, . Statistics and Data. Prevalence of Blindness Data. Data Tables [online]. 2007, https://nei.nih.gov/eyedata/pbd_tables

3 

Fine SL, Berger JW, Maguire MG and Ho AC: Age-related macular degeneration. N Engl J Med. 342:483–492. 2000. View Article : Google Scholar : PubMed/NCBI

4 

Ciulla TA, Harris A and Martin BJ: Ocular perfusion and age-related macular degeneration. Acta Ophthalmol Scand. 79:108–115. 2001. View Article : Google Scholar : PubMed/NCBI

5 

Moshfeghi AA, Rosenfeld PJ, Puliafito CA, Michels S, Marcus EN, Lenchus JD and Venkatraman AS: Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration: Twenty-four-week results of an uncontrolled open-label clinical study. Ophthalmology. 113:2002.e1–2002.e12. 2006. View Article : Google Scholar

6 

Rosenfeld PJ, Fung AE and Puliafito CA: Optical coherence tomography findings after an intravitreal injection of bevacizumab (avastin) for macular edema from central retinal vein occlusion. Ophthalmic Surg Lasers Imaging. 36:336–339. 2005. View Article : Google Scholar : PubMed/NCBI

7 

Bakri SJ, Cameron JD, McCannel CA, Pulido JS and Marler RJ: Absence of histologic retinal toxicity of intravitreal bevacizumab in a rabbit model. Am J Ophthalmol. 142:162–164. 2006. View Article : Google Scholar : PubMed/NCBI

8 

Manzano RP, Peyman GA, Khan P and Kivilcim M: Testing intravitreal toxicity of bevacizumab (Avastin). Retina. 26:257–261. 2006. View Article : Google Scholar : PubMed/NCBI

9 

Kiss C, Michels S, Prager F, Weigert G, Geitzenauer W and Schmidt-Erfurth U: Anterior chamber inflammatory activity in patients with neovascular age-related macular degeneration treated with intravitreal bevacizumab (Avastin). Retina. 26:877–881. 2006. View Article : Google Scholar : PubMed/NCBI

10 

Spitzer MS, Wallenfels-Thilo B, Sierra A, Yoeruek E, Peters S, Henke-Fahle S, Bartz-Schmidt KU and Szurman P; Tuebingen Bevacizumab Study Group, : Antiproliferative and cytotoxic properties of bevacizumab on different ocular cells. Br J Ophthalmol. 90:1316–1321. 2006. View Article : Google Scholar : PubMed/NCBI

11 

Ziemssen F, Warga M, Neuhann IM, Leitritz M, Biester S, Grisanti S and Bartz-Schmidt KU: Does intravitreal injection of bevacizumab have an effect on the blood-aqueus barrier function? Br J Ophthalmol. 90:9222006. View Article : Google Scholar : PubMed/NCBI

12 

Mangione CM, Lee PP, Gutierrez PR, Spritzer K, Berry S and Hays RD; National Eye Institute Visual Function Questionnaire Field Test Investigators, : Development of the 25-item National Eye Institute Visual Function Questionnaire. Arch Ophthalmol. 119:1050–1058. 2001. View Article : Google Scholar : PubMed/NCBI

13 

Mordenti J, Cuthbertson RA, Ferrara N, Thomsen K, Berleau L, Licko V, Allen PC, Valverde CR, meng YG, Fei DT, et al: Comparisons of the intraocular tissue distribution, pharmacokinetics, and safety of 125I-labeled full-length and Fab antibodies in rhesus monkeys following intravitreal administration. Toxicol Pathol. 27:536–544. 1999. View Article : Google Scholar : PubMed/NCBI

14 

Rosenfeld PJ, Moshfeghi AA and Puliafito CA: Optical coherence tomography findings after an intravitreal injection of bevacizumab (avastin) for neovascular age-related macular degeneration. Ophthalmic Surg Lasers Imaging. 36:331–335. 2005. View Article : Google Scholar : PubMed/NCBI

15 

Shahar J, Avery RL, Heilweil G, Barak A, Zemel E, Lewis GP, Johnson PT, Fisher SK, Perlman I and Loewenstein A: Electrophysiologic and retinal penetration studies following intravitreal injection of bevacizumab (Avastin). Retina. 26:262–269. 2006. View Article : Google Scholar : PubMed/NCBI

16 

Spaide RF, Laud K, Fine HF, Klancnik JM Jr, Meyerle CB, Yannuzzi LA, Sorenson J, Slakter J, Fisher YL and Cooney MJ: Intravitreal bevacizumab treatment of choroidal neovascularization secondary to age-related macular degeneration. Retina. 26:383–390. 2006. View Article : Google Scholar : PubMed/NCBI

17 

Heiduschka P, Fietz H, Hofmeister S, Schultheiss S, Mack AF, Peters S, Ziemssen F, Niggemann B, Julien S, Bartz-Schmidt KU, et al Tübingen Bevacizumab Study Group, : Penetration of bevacizumab through the retina after intravitreal injection in the monkey. Invest Ophthalmol Vis Sci. 48:2814–2823. 2007. View Article : Google Scholar : PubMed/NCBI

18 

Iturralde D, Spaide RF, Meyerle CB, Klancnik JM, Yannuzzi LA, Fisher YL, Sorenson J, Slakter JS, Freund KB, Cooney M, et al: Intravitreal bevacizumab (Avastin) treatment of macular edema in central retinal vein occlusion: A short-term study. Retina. 26:279–284. 2006. View Article : Google Scholar : PubMed/NCBI

19 

Spaide RF and Fisher YL: Intravitreal bevacizumab (Avastin) treatment of proliferative diabetic retinopathy complicated by vitreous hemorrhage. Retina. 26:275–278. 2006. View Article : Google Scholar : PubMed/NCBI

20 

Avery RL: Regression of retinal and iris neovascularization after intravitreal bevacizumab (Avastin) treatment. Retina. 26:352–354. 2006. View Article : Google Scholar : PubMed/NCBI

21 

Avery RL, Pearlman J, Pieramici DJ, Rabena MD, Castellarin AA, Nasir MA, Giust MJ, Wendel R and Patel A: Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy. Ophthalmology. 113:1695.e1–1695.e15. 2006. View Article : Google Scholar

22 

Aisenbrey S, Ziemssen F, Völker M, Gelisken F, Szurman P, Jaissle G, Grisanti S and Bartz-Schmidt KU: Intravitreal bevacizumab (Avastin) for occult choroidal neovascularization in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 245:941–948. 2007. View Article : Google Scholar : PubMed/NCBI

23 

Avery RL, Pieramici DJ, Rabena MD, Castellarin AA, Nasir MA and Giust MJ: Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration. Ophthalmology. 113:363–372.e5. 2006. View Article : Google Scholar : PubMed/NCBI

24 

Yoganathan P, Deramo VA, Lai JC, Tibrewala RK and Fastenberg DM: Visual improvement following intravitreal bevacizumab (Avastin) in exudative age-related macular degeneration. Retina. 26:994–998. 2006. View Article : Google Scholar : PubMed/NCBI

25 

Sakaguchi H, Ikuno Y, Gomi F, Kamei M, Sawa M, Tsujikawa M, Oshima Y, Kusaka S and Tano Y: Intravitreal injection of bevacizumab for choroidal neovascularisation associated with pathological myopia. Br J Ophthalmol. 91:161–165. 2007. View Article : Google Scholar : PubMed/NCBI

26 

Laud K, Spaide RF, Freund KB, Slakter J and Klancnik JM Jr: Treatment of choroidal neovascularization in pathologic myopia with intravitreal bevacizumab. Retina. 26:960–963. 2006. View Article : Google Scholar : PubMed/NCBI

27 

Tewari A, Dhalla MS and Apte RS: Intravitreal bevacizumab for treatment of choroidal neovascularization in pathologic myopia. Retina. 26:1093–1094. 2006. View Article : Google Scholar : PubMed/NCBI

28 

Teixeira A, Moraes N, Farah ME and Bonomo PP: Choroidal neovascularization treated with intravitreal injection of bevacizumab (Avastin) in angioid streaks. Acta Ophthalmol Scand. 84:835–836. 2006. View Article : Google Scholar : PubMed/NCBI

29 

Lommatzsch A, Spital G, Trieschmann M and Pauleikhoff D: Intraocular application of bevacizumab for the treatment of choroidal neovascularization secondary to angioid streaks. Ophthalmologe. 104:325–328. 2007.(In German). View Article : Google Scholar : PubMed/NCBI

30 

Jorge R, Costa RA, Calucci D and Scott IU: Intravitreal bevacizumab (Avastin) associated with the regression of subretinal neovascularization in idiopathic juxtafoveolar retinal telangiectasis. Graefes Arch Clin Exp Ophthalmol. 245:1045–1048. 2007. View Article : Google Scholar : PubMed/NCBI

31 

Munteanu M and Rosca C: Repositioning and follow-up of intralenticular dexamethasone implant. J Cataract Refract Surg. 39:1271–1274. 2013. View Article : Google Scholar : PubMed/NCBI

32 

Jianu DC, Jianu SN, Dan TF, Motoc AGM and Poenaru M: Pulsatile tinnitus caused by a dilated left petrosquamosal sinus. Rom J Morphol Embryol. 57:319–322. 2016.PubMed/NCBI

33 

Stanca HT, Suvac E, Munteanu M, Jianu DC, Motoc AGM, Roşca GC and Boruga O: Giant cell arteritis with arteritic anterior ischemic optic neuropathy. Rom J Morphol Embryol. 58:281–285. 2017.PubMed/NCBI

34 

Caruntu C, Boda D, Dumitrascu G, Constantin C and Neagu M: Proteomics focusing on immune markers in psoriatic arthritis. Biomarkers Med. 9:513–528. 2015. View Article : Google Scholar

35 

Solomon I, Voiculescu VM, Caruntu C, Lupu M, Popa A, Ilie MA, Albulescu R, Caruntu A, Tanase C, Constantin C, et al: Neuroendocrine factors and head and neck squamous cell carcinoma: An affair to remember. Dis Markers. 2018:97878312018. View Article : Google Scholar : PubMed/NCBI

36 

Ion A, Popa IM, Papagheorghe LML, Lisievici C, Lupu M, Voiculescu V, Caruntu C and Boda D: Proteomic approaches to biomarker discovery in cutaneous T-cell lymphoma. Dis Markers. 2016:96024722016. View Article : Google Scholar : PubMed/NCBI

37 

Lupu M, Caruntu A, Caruntu C, Papagheorghe LML, Ilie MA, Voiculescu V, Boda D, Constantin C, Tanase C, Sifaki M, et al: Neuroendocrine factors: The missing link in non-melanoma skin cancer (Review). Oncol Rep. 38:1327–1340. 2017. View Article : Google Scholar : PubMed/NCBI

38 

Batani A, Brănișteanu DE, Ilie MA, Boda D, Ianosi S, Ianosi G and Caruntu C: Assessment of dermal papillary and microvascular parameters in psoriasis vulgaris using in vivo reflectance confocal microscopy. Exp Ther Med. 15:1241–1246. 2018.PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Stanca HT, Stanca S, Tabacaru B, Boruga M and Balta F: Bevacizumab in Wet AMD treatment: A tribute to the thirteen years of experience from the beginning of the anti‑VEGF era in Romania. Exp Ther Med 18: 4993-5000, 2019.
APA
Stanca, H.T., Stanca, S., Tabacaru, B., Boruga, M., & Balta, F. (2019). Bevacizumab in Wet AMD treatment: A tribute to the thirteen years of experience from the beginning of the anti‑VEGF era in Romania. Experimental and Therapeutic Medicine, 18, 4993-5000. https://doi.org/10.3892/etm.2019.7858
MLA
Stanca, H. T., Stanca, S., Tabacaru, B., Boruga, M., Balta, F."Bevacizumab in Wet AMD treatment: A tribute to the thirteen years of experience from the beginning of the anti‑VEGF era in Romania". Experimental and Therapeutic Medicine 18.6 (2019): 4993-5000.
Chicago
Stanca, H. T., Stanca, S., Tabacaru, B., Boruga, M., Balta, F."Bevacizumab in Wet AMD treatment: A tribute to the thirteen years of experience from the beginning of the anti‑VEGF era in Romania". Experimental and Therapeutic Medicine 18, no. 6 (2019): 4993-5000. https://doi.org/10.3892/etm.2019.7858
Copy and paste a formatted citation
x
Spandidos Publications style
Stanca HT, Stanca S, Tabacaru B, Boruga M and Balta F: Bevacizumab in Wet AMD treatment: A tribute to the thirteen years of experience from the beginning of the anti‑VEGF era in Romania. Exp Ther Med 18: 4993-5000, 2019.
APA
Stanca, H.T., Stanca, S., Tabacaru, B., Boruga, M., & Balta, F. (2019). Bevacizumab in Wet AMD treatment: A tribute to the thirteen years of experience from the beginning of the anti‑VEGF era in Romania. Experimental and Therapeutic Medicine, 18, 4993-5000. https://doi.org/10.3892/etm.2019.7858
MLA
Stanca, H. T., Stanca, S., Tabacaru, B., Boruga, M., Balta, F."Bevacizumab in Wet AMD treatment: A tribute to the thirteen years of experience from the beginning of the anti‑VEGF era in Romania". Experimental and Therapeutic Medicine 18.6 (2019): 4993-5000.
Chicago
Stanca, H. T., Stanca, S., Tabacaru, B., Boruga, M., Balta, F."Bevacizumab in Wet AMD treatment: A tribute to the thirteen years of experience from the beginning of the anti‑VEGF era in Romania". Experimental and Therapeutic Medicine 18, no. 6 (2019): 4993-5000. https://doi.org/10.3892/etm.2019.7858
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