|
1
|
Lee J, Cuddihy MJ and Kotov NA:
Three-dimensional cell culture matrices: State of the art. Tissue
Eng Part B Rev. 14:61–86. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Haycock JW: 3D cell culture: A review of
current approaches and techniques. Methods Mol Biol. 695:1–15.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Lee SI, Yeo SI, Kim BB, Ko Y and Park JB:
Formation of size-controllable spheroids using gingiva-derived stem
cells and concave microwells: Morphology and viability tests.
Biomed Rep. 4:97–101. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Wang W, Itaka K, Ohba S, Nishiyama N,
Chung UI, Yamasaki Y and Kataoka K: 3D spheroid culture system on
micropatterned substrates for improved differentiation efficiency
of multipotent mesenchymal stem cells. Biomaterials. 30:2705–2715.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Justice BA, Badr NA and Felder RA: 3D cell
culture opens new dimensions in cell-based assays. Drug Discov
Today. 14:102–107. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Li Z, Araoka T, Wu J, Liao HK, Li M, Lazo
M, Zhou B, Sui Y, Wu MZ, Tamura I, et al: 3D culture supports
long-term expansion of mouse and human nephrogenic progenitors.
Cell Stem Cell. 19:516–529. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Jin SH, Lee JE, Yun JH, Kim I, Ko Y and
Park JB: Isolation and characterization of human mesenchymal stem
cells from gingival connective tissue. J Periodontal Res.
50:461–467. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Tae JY, Lee H, Lee H, Ko Y and Park JB:
Osteogenic potential of cell spheroids composed of varying ratios
of gingiva-derived and bone marrow stem cells using concave
microwells. Exp Ther Med. 16:2287–2294. 2018.PubMed/NCBI
|
|
9
|
Wajid N, Anwar SS, Ali F, Zahoor M, Hamid
N, Aslam MM and Ali A: Medicinal significance of lovastatin. Int J
Pharm Sci Res. 6:971–977. 2015.
|
|
10
|
Thibault A, Samid D, Tompkins AC, Figg WD,
Cooper MR, Hohl RJ, Trepel J, Liang B, Patronas N, Venzon DJ, et
al: Phase I study of lovastatin, an inhibitor of the mevalonate
pathway, in patients with cancer. Clin Cancer Res. 2:483–491.
1996.PubMed/NCBI
|
|
11
|
Maeda T, Kawane T and Horiuchi N: Statins
augment vascular endothelial growth factor expression in
osteoblastic cells via inhibition of protein prenylation.
Endocrinology. 144:681–692. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Lee H, Lee H, Na CB and Park JB: Effects
of simvastatin on the viability and secretion of vascular
endothelial growth factor of cell spheroids cultured in growth
media. Implant Dent. 27:480–487. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Maeda T, Matsunuma A, Kurahashi I,
Yanagawa T, Yoshida H and Horiuchi N: Induction of osteoblast
differentiation indices by statins in MC3T3-E1 cells. J Cell
Biochem. 92:458–471. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Yang SH, Lin HY, Changou CA, Chen CH, Liu
YR, Wang J, Jiang X, Luh F and Yen Y: Integrin β3 and LKB1 are
independently involved in the inhibition of proliferation by
lovastatin in human intrahepatic cholangiocarcinoma. Oncotarget.
7:362–373. 2016.PubMed/NCBI
|
|
15
|
Park JB, Zhang H, Lin CY, Chung CP, Byun
Y, Park YS and Yang VC: Simvastatin maintains osteoblastic
viability while promoting differentiation by partially regulating
the expressions of estrogen receptors α. J Surg Res. 174:278–283.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Lee SI, Ko Y and Park JB: Evaluation of
the maintenance of stemness, viability, and differentiation
potential of gingiva-derived stem-cell spheroids. Exp Ther Med.
13:1757–1764. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Mundy G, Garrett R, Harris S, Chan J, Chen
D, Rossini G, Boyce B, Zhao M and Gutierrez G: Stimulation of bone
formation in vitro and in rodents by statins. Science.
286:1946–1949. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Park JB: The use of simvastatin in bone
regeneration. Med Oral Patol Oral Cir Bucal. 14:e485–e488.
2009.PubMed/NCBI
|
|
19
|
Park JB: Combination of simvastatin and
bone morphogenetic protein-2 enhances the differentiation of
osteoblasts by regulating the expression of phospho-Smad1/5/8. Exp
Ther Med. 4:303–306. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Garrett IR, Gutierrez GE, Rossini G, Nyman
J, McCluskey B, Flores A and Mundy GR: Locally delivered lovastatin
nanoparticles enhance fracture healing in rats. J Orthop Res.
25:1351–1357. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Yoshii T, Hafeman AE, Nyman JS, Esparza
JM, Shinomiya K, Spengler DM, Mundy GR, Gutierrez GE and Guelcher
SA: A sustained release of lovastatin from biodegradable,
elastomeric polyurethane scaffolds for enhanced bone regeneration.
Tissue Eng Part A. 16:2369–2379. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Li Y, Müller AL, Ngo MA, Sran K, Bellan D,
Arora RC, Kirshenbaum LA and Freed DH: Statins impair survival of
primary human mesenchymal progenitor cells via mevalonate
depletion, NF-κB signaling, and Bnip3. J Cardiovasc Transl Res.
8:96–105. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Torres CG, Olivares A and Stoore C:
Simvastatin exhibits antiproliferative effects on spheres derived
from canine mammary carcinoma cells. Oncol Rep. 33:2235–2244. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Xu R, Chen J, Cong X, Hu S and Chen X:
Lovastatin protects mesenchymal stem cells against hypoxia- and
serum deprivation-induced apoptosis by activation of PI3K/Akt and
ERK1/2. J Cell Biochem. 103:256–269. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Li Y, Zhang D, Zhang Y, He G and Zhang F:
Augmentation of neovascularization in murine hindlimb ischemia by
combined therapy with simvastatin and bone marrow-derived
mesenchymal stem cells transplantation. J Biomed Sci. 17:752010.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Jeong SH, Lee JE, Kim BB, Ko Y and Park
JB: Evaluation of the effects of cimicifugae rhizoma on the
morphology and viability of mesenchymal stem cells. Exp Ther Med.
10:629–634. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Lei M, Li K, Li B, Gao LN, Chen FM and Jin
Y: Mesenchymal stem cell characteristics of dental pulp and
periodontal ligament stem cells after in vivo transplantation.
Biomaterials. 35:6332–6343. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Kim JH, Ko SY, Lee JH, Kim DH and Yun JH:
Evaluation of the periodontal regenerative properties of patterned
human periodontal ligament stem cell sheets. J Periodontal Implant
Sci. 47:402–415. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Seo BM, Miura M, Gronthos S, Bartold PM,
Batouli S, Brahim J, Young M, Robey PG, Wang CY and Shi S:
Investigation of multipotent postnatal stem cells from human
periodontal ligament. Lancet. 364:149–155. 2004. View Article : Google Scholar : PubMed/NCBI
|
