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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November-2019 Volume 18 Issue 5

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Article Open Access

High mobility group box protein 1 neutralization therapy in ovine bacteremia: Lessons learned from an ovine septic shock model incorporating intensive care support

Natalie E. Stevens, Coralie H. Nash, Cara K. Fraser, Tim R. Kuchel, Matthew J. Maiden, Marianne J. Chapman, Kerrilyn R. Diener, John D. Hayball
Pages: 3271-3280
Published online on: 30 August 2019

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Article Open Access

PKCδ promotes fertilization of mouse embryos in early development via the Cdc25B signaling pathway

Yanchun Liu, Xin Deng, Didi Wu, Minglin Jin, Bingzhi Yu
Pages: 3281-3290
Published online on: 29 August 2019

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Article Open Access

Identification of potential key genes in esophageal adenocarcinoma using bioinformatics

Zhiyu Dong, Junwen Wang, Haiqin Zhang, Tingting Zhan, Ying Chen, Shuchang Xu
Pages: 3291-3298
Published online on: 05 September 2019

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Article Open Access

MicroRNA‑204 may participate in the pathogenesis of hypoxic‑ischemic encephalopathy through targeting KLLN

Ronglin Chen, Meixia Wang, Shaopin Fu, Feng Cao, Pengkai Duan, Jiefu Lu
Pages: 3299-3306
Published online on: 26 August 2019

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Article

Adropin reduces hypoxia/reoxygenation‑induced myocardial injury via the reperfusion injury salvage kinase pathway

Lingzhen Wu, Jun Fang, Xun Yuan, Chang Xiong, Lianglong Chen
Pages: 3307-3314
Published online on: 26 August 2019

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Article Open Access

Smoking alters the evolutionary trajectory of non‑small cell lung cancer

Xiao‑Jun Yu, Gang Chen, Jun Yang, Guo‑Can Yu, Peng‑Fei Zhu, Zheng‑Ke Jiang, Kan Feng, Yong Lu, Bin Bao, Fang‑Ming Zhong
Pages: 3315-3324
Published online on: 29 August 2019

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Article Open Access

MicroRNA‑138 attenuates myocardial ischemia reperfusion injury through inhibiting mitochondria‑mediated apoptosis by targeting HIF1‑α

Yan Liu, Jianfeng Zou, Xiaoyan Liu, Quan Zhang
Pages: 3325-3332
Published online on: 05 September 2019

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Article Open Access

Cell sheets of co‑cultured BMP‑2‑modified bone marrow stromal cells and endothelial progenitor cells accelerate bone regeneration in vitro

Jia He, Xuesong Han, Songmei Wang, Ying Zhang, Xiaoming Dai, Boyan Liu, Liu Liu, Xian Zhao
Pages: 3333-3340
Published online on: 06 September 2019

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Article Open Access

Efficacy and safety of combination of magnesium sulfate, phentolamine and nifedipine in treatment of patients with hypertensive disorder complicating pregnancy

Jinggui Zhang, Jun Li
Pages: 3341-3346
Published online on: 30 August 2019

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Article Open Access

Puerarin inhibits apoptosis and inflammation in myocardial cells via PPARα expression in rats with chronic heart failure Retraction in /10.3892/etm.2025.12916

Le He, Tong Wang, Bing‑Wei Chen, Feng‑Min Lu, Jing Xu
Pages: 3347-3356
Published online on: 06 September 2019

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Article Open Access

Activation of the primary motor cortex using fully‑implanted electrical sciatic nerve stimulation

Xiaodong Lv, Rongyu Tang, Zhaolong Gao, Dingyin Hu, Guanghui Li, Yiran Lang, Jiping He
Pages: 3357-3364
Published online on: 09 September 2019

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Article Open Access

Angelicin inhibits the malignant behaviours of human cervical cancer potentially via inhibiting autophagy

Yiran Wang, Yueqi Chen, Xuedan Chen, Yan Liang, Dapeng Yang, Jiao Dong, Neng Yang, Zhiqing Liang
Pages: 3365-3374
Published online on: 06 September 2019

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Article Open Access

Factors affecting the therapeutic effect of botulinum toxin A on trigeminal neuralgia: A follow‑up retrospective study of 152 patients

Haifeng Zhang, Yajun Lian, Nanchang Xie, Xuan Cheng, Chen Chen, Hongliang Xu, Yake Zheng
Pages: 3375-3382
Published online on: 09 September 2019

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Article Open Access

Clinical efficacy of acetylcysteine combined with tetrandrine tablets in the treatment of silicosis and the effect on serum IL-6 and TNF-α

Jianling Sun, Pingping Song, Yan Wang, Yanxia Chen
Pages: 3383-3388
Published online on: 30 August 2019

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Article Open Access

Detection of ctDNA in the plasma of patients with papillary thyroid carcinoma

Huiqiang Li, Jiangman Zhao, Jianhua Zhang, Congren Wang, Mingzhu Li, Shouxin Wu, Zijian Su, Qunxiong Pan
Pages: 3389-3396
Published online on: 11 September 2019

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Article Open Access

Resveratrol ameliorates brain injury via the TGF‑β‑mediated ERK signaling pathway in a rat model of cerebral hemorrhage

Riguang Zhao, Kun Zhao, Hongjun Su, Peng Zhang, Na Zhao
Pages: 3397-3404
Published online on: 26 August 2019

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Article Open Access

Application of nomograms in the prediction of overall survival and cancer‑specific survival in patients with T1 high‑grade bladder cancer

Fucai Tang, Zhaohui He, Zechao Lu, Weijia Wu, Yiwen Chen, Genggeng Wei, Yangzhou Liu
Pages: 3405-3414
Published online on: 06 September 2019

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Article Open Access

Sphingosine‑1‑phosphate induces islet β‑cell proliferation and decreases cell apoptosis in high‑fat diet/streptozotocin diabetic mice

Yizhi He, Bingyin Shi, Xinrui Zhao, Jing Sui
Pages: 3415-3424
Published online on: 11 September 2019

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Article Open Access

Lovastatin increases the proliferation and osteoblastic differentiation of human gingiva‑derived stem cells in three‑dimensional cultures

Bo‑Bae Kim, Jae‑Yong Tae, Youngkyung Ko, Jun‑Beom Park
Pages: 3425-3430
Published online on: 05 September 2019

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Article Open Access

Wnt/β‑catenin signaling pathway regulates asthma airway remodeling by influencing the expression of c‑Myc and cyclin D1 via the p38 MAPK‑dependent pathway

Xiao‑Xiao Jia, Ting‑Ting Zhu, Yue Huang, Xin‑Xin Zeng, Hong Zhang, Wei‑Xi Zhang
Pages: 3431-3438
Published online on: 09 September 2019

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Article Open Access

Identification of key candidate genes and pathways in glioblastoma by integrated bioinformatical analysis

Lei Li, Xiaohui Liu, Xiaoye Ma, Xianyu Deng, Tao Ji, Pingping Hu, Ronghao Wan, Huijia Qiu, Daming Cui, Liang Gao
Pages: 3439-3449
Published online on: 05 September 2019

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Article Open Access

Decreased expression of microRNA‑145 promotes the biological functions of fibroblasts in hypertrophic scar tissues by upregulating the expression of transcription factor SOX‑9

Shoujie Wang, Caiyun Li, Yijia Yu, Jianjun Qiao
Pages: 3450-3460
Published online on: 05 September 2019

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Article Open Access

Dysbiosis of Gram‑negative gut microbiota and the associated serum lipopolysaccharide exacerbates inflammation in type 2 diabetic patients with chronic kidney disease

Maria V. Salguero, Mohammed A. I. Al‑Obaide, Ruchi Singh, Timo Siepmann, Tetyana L. Vasylyeva
Pages: 3461-3469
Published online on: 26 August 2019

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Article Open Access

Efficacy of electroacupuncture combined with probiotics for depression and chronic diarrhea in patients and effect on serum inflammatory cytokines, NE and BDNF

Wei Huang, Wei Gan, An Huang, Yulei Fu, Yuzhi Shang, Yue Chen, Zhao Tian, Yun Zhang, Gang Fang
Pages: 3470-3474
Published online on: 06 September 2019

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Article Open Access

Long non‑coding RNA XIST promotes cell proliferation and migration through targeting miR‑133a in bladder cancer

Keqin Zhou, Jinrui Yang, Xurui Li, Wenjie Chen
Pages: 3475-3483
Published online on: 29 August 2019

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Article Open Access

Exposure to atmospheric pollutants is associated with alterations of gut microbiota in spontaneously hypertensive rats

Dongmei Chen, Chunling Xiao, Huanrong Jin, Biao Yang, Jiayu Niu, Siyuan Yan, Ye Sun, Yuan Zhou, Xiangming Wang
Pages: 3484-3492
Published online on: 23 August 2019

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Article Open Access

KLF4 overexpression decreases the viability, invasion and migration of papillary thyroid cancer cells

Qianzhu Wang, Jian Xu, Yong Chen, Limin Liu
Pages: 3493-3501
Published online on: 02 September 2019

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Article Open Access

Expression of TGF‑β1 and VEGF in patients with Achilles tendon rupture and the clinical efficacy

Juncheng Cui, Zhiwei Chen, Wente Wu
Pages: 3502-3508
Published online on: 30 August 2019

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Article Open Access

Associations between the severity of reflux esophagitis in children and changes in oxidative stress, serum inflammation, vasoactive intestinal peptide and motilin

Yingqin Deng, Li Pan, Wenjie Qian
Pages: 3509-3513
Published online on: 06 September 2019

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Article Open Access

Germacrone cooperates with dexmedetomidine to alleviate high‑fat diet‑induced type 2 diabetes mellitus via upregulating AMPKα1 expression Retraction in /10.3892/etm.2024.12406

Yang Sun, Lanlan Li, Jun Wu, Bing Gong, Haiyan Liu
Pages: 3514-3524
Published online on: 09 September 2019

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Article Open Access

miR‑205‑5p downregulation decreases gemcitabine sensitivity of breast cancer cells via ERp29 upregulation

Changpo Ma, Xuejun Shi, Wenchao Guo, Fukai Feng, Guangshun Wang
Pages: 3525-3533
Published online on: 30 August 2019

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Article Open Access

Knockdown of lncRNA CCEPR suppresses colorectal cancer progression

Yuxia Duan, Zhixue Fang, Zeya Shi, Ling Zhang
Pages: 3534-3542
Published online on: 26 August 2019

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Article Open Access

MicroRNA‑21‑5p targeting PDCD4 suppresses apoptosis via regulating the PI3K/AKT/FOXO1 signaling pathway in tongue squamous cell carcinoma

Changfu Liu, Zhou Tong, Jingyu Tan, Zengxi Xin, Zhiying Wang, Luming Tian
Pages: 3543-3551
Published online on: 02 September 2019

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Article Open Access

Application of a modified optical fiber in targeted percutaneous laser disc decompression of lumbar disc herniation: A retrospective study

Chao Meng, Yujun Li, Shijie Wang, Junmin Yu, Dewei Kou, Chuansheng Liu
Pages: 3552-3562
Published online on: 06 September 2019

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Case Report Open Access

Cystic adventitial disease of femoral vein presenting as enlarging lower limb swelling and pain: Two case reports and review of the literature

Peng Liu, Bin Yan, Yanhui Zhang, Jingwei Yan, Chong Ma, Guodong Wang, Tao Jian, Ziqiang Sun
Pages: 3563-3567
Published online on: 09 September 2019

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Article Open Access

Effect of HCV treatment response on insulin resistance: A systematic review and meta‑analysis Corrigendum in /10.3892/etm.2019.8334

Jing‑Hong Hu, Ming‑Ling Chang, Nai‑Jen Liu, Chau‑Ting Yeh, Tung‑Jung Huang
Pages: 3568-3578
Published online on: 11 September 2019

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Article Open Access

Screening and identification of biomarkers associated with clinicopathological parameters and prognosis in oral squamous cell carcinoma

Qiqi Wu, Ruoyan Cao, Juan Chen, Xiaoli Xie
Pages: 3579-3587
Published online on: 11 September 2019

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Article Open Access

Effect of laparoscopic myomectomy on serum levels of IL‑6 and TAC, and ovarian function

Yanling Hu, Liyao Yu, Fen Xia, Fengqi Liang, Chao Cheng, Yuhua Huang, Linqi Xiao
Pages: 3588-3594
Published online on: 26 August 2019

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Article

Changes of fractional anisotropy and RGMa in crossed cerebellar diaschisis induced by middle cerebral artery occlusion

Yong Zhang, Xiao Wang, Jingliang Cheng, Yanan Lin, Lu Yang, Zhenghao Cao, Yunjun Yang
Pages: 3595-3602
Published online on: 09 September 2019

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Article

Sphingolipid metabolism in type 2 diabetes and associated cardiovascular complications

Jing Sui, Mingqian He, Yue Wang, Xinrui Zhao, Yizhi He, Bingyin Shi
Pages: 3603-3614
Published online on: 06 September 2019

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Article

Efficacy of unilateral transverse process‑pedicle and bilateral puncture techniques in percutaneous kyphoplasty for Kummell disease

Xiao‑Ming Xiong, Yu‑Liang Sun, Si‑Mao Song, Mao‑Yi Yang, Jie Zhou, Dun Wan, Xuan‑Geng Deng, Hua‑Gang Shi
Pages: 3615-3621
Published online on: 06 September 2019

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Article

Effect and mechanism of microRNA‑10b on proliferation and invasion of esophageal cancer cells

Yi Liu, Adili Salai, Dan He, Shengli Gao, Wei Zeng
Pages: 3622-3630
Published online on: 26 August 2019

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Article

Evaluation and prognostic value of Cv‑aCO2/Da‑vO2 in patients with septic shock receiving fluid resuscitation Cv‑aCO2/Ca‑vO2

Huiling Zang, Xiaohui Shen, Shengchi Wang, Zhihong He, Hui Cheng
Pages: 3631-3635
Published online on: 28 August 2019

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Article

Protease‑activated receptor 2 protects against myocardial ischemia‑reperfusion injury through the lipoxygenase pathway and TRPV1 channels

Beihua Zhong, Shuangtao Ma, Donna H. Wang
Pages: 3636-3642
Published online on: 09 September 2019

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Article

Wnt1 silencing enhances neurotoxicity induced by paraquat and maneb in SH‑SY5Y cells

Cui Huang, Jing Ma, Bai‑Xiang Li, Yan Sun
Pages: 3643-3649
Published online on: 30 August 2019

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Article

MicroRNA‑877 is downregulated in cervical cancer and directly targets MACC1 to inhibit cell proliferation and invasion

Fanxu Meng, Jian Ou, Jinyu Liu, Xindi Li, Yanli Meng, Ling Yan, Ping Deng, Baosheng Sun
Pages: 3650-3658
Published online on: 09 September 2019

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Article

MicroRNA‑410 participates in the pathological process of postmenopausal osteoporosis by downregulating bone morphogenetic protein‑2

Hao Zhang, Wenbin Ding, Fang Ji, Dajiang Wu
Pages: 3659-3666
Published online on: 11 September 2019

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Article

Feasibility of low‑dose infusion of alteplase for unsuccessful thrombolysis with urokinase in deep venous thrombosis

Maofeng Gong, Boxiang Zhao, Xu He, Jianping Gu, Guoping Chen
Pages: 3667-3674
Published online on: 26 August 2019

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Article

Factors affecting pregnancy outcomes following the surgical removal of intrauterine adhesions and subsequent in vitro fertilization and embryo transfer

Xuechun Wang, Jingsong Yi, Xi Xie, Shengrong Du, Liying Li, Xiuqiong Zheng
Pages: 3675-3680
Published online on: 23 August 2019

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Article

Tetrahydrocurcumin protects against spinal cord injury and inhibits the oxidative stress response by regulating FOXO4 in model rats

Jiancheng Xi, Xiaobo Luo, Yipeng Wang, Jinglong Li, Lixin Guo, Guangseng Wu, Qingui Li
Pages: 3681-3687
Published online on: 05 September 2019

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Correction Open Access

[Erratum] Changes in expression of p53 and inflammatory factors in patients with ulcerative colitis

Hui Su, Qian Kang, Haihong Wang, Hui Yin, Linghui Duan, Yuli Liu, Ruying Fan
Pages: 3688-3688
Published online on: 10 September 2019

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Article Open Access

Mechanism associated with aberrant lncRNA MEG3 expression in gestational diabetes mellitus

Hailing Zhang
Pages: 3699-3706
Published online on: 27 September 2019

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Article Open Access

Carnosic acid protects against lipopolysaccharide‑induced acute lung injury in mice

Quan Li, Ling Liu, Haijun Sun, Kunyue Cao
Pages: 3707-3714
Published online on: 23 September 2019

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Article Open Access

Jatrorrhizine suppresses the antimicrobial resistance of methicillin‑resistant Staphylococcus aureus

Haiming Yu, Yuefei Wang, Xiaoqing Wang, Junjie Guo, Hui Wang, Hao Zhang, Fengxia Du
Pages: 3715-3722
Published online on: 23 September 2019

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Article Open Access

Misdiagnosed and mismanaged atypical spinal tuberculosis: A case series report

Feifei Pu, Jing Feng, Lin Yang, Lin Zhang, Ping Xia
Pages: 3723-3728
Published online on: 17 September 2019

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Article Open Access

Downregulation of microRNA‑3934‑5p induces apoptosis and inhibits the proliferation of neuroblastoma cells by targeting TP53INP1

Wei Ye, Fulv Liang, Chen Ying, Maolin Zhang, Dongbo Feng, Xinyu Jiang
Pages: 3729-3736
Published online on: 13 September 2019

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Case Report Open Access

A novel mutation in a common pathogenic gene (SETD5) associated with intellectual disability: A case report

Yu‑Lian Fang, Rui‑Ping Zhang, Yi‑Zheng Wang, Li‑Rong Cao, Yu‑Qin Zhang, Chun‑Quan Cai
Pages: 3737-3740
Published online on: 27 September 2019

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Article Open Access

Astragaloside IV regulates NF‑κB‑mediated cellular senescence and apoptosis of hepatic stellate cells to suppress PDGF‑BB‑induced activation

Zhiwei Chen, Ling Yao, Yuanyuan Liu, Zheng Pan, Shuang Peng, Guoguo Wan, Junxiong Cheng, Jianwei Wang, Wenfu Cao
Pages: 3741-3750
Published online on: 25 September 2019

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Article Open Access

Knockdown of interferon‑stimulated gene 15 affects the sensitivity of hepatocellular carcinoma cells to norcantharidin

Baoxiang Chen, Shuqiang Jin, Bin Bai, Zhi Li, Caifang Ni, Yansen Liu
Pages: 3751-3758
Published online on: 19 September 2019

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Article Open Access

Overexpression of thymosin β10 correlates with disease progression and poor prognosis in bladder cancer

Bingwei Wang, Zhenwei Wang, Tao Zhang, Guosheng Yang
Pages: 3759-3766
Published online on: 13 September 2019

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Article Open Access

β‑asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal‑regulated kinase signaling pathway Retraction in /10.3892/etm.2026.13063

Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong Li
Pages: 3767-3774
Published online on: 18 September 2019

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Article Open Access

Crocetin protects against fulminant hepatic failure induced by lipopolysaccharide/D‑galactosamine by decreasing apoptosis, inflammation and oxidative stress in a rat model

Ke Gao, Faquan Liu, Xi Chen, Mengxue Chen, Qingwen Deng, Xingjian Zou, Hongxing Guo
Pages: 3775-3782
Published online on: 19 September 2019

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Article Open Access

Mechanism of H2S‑mediated ROCK inhibition of total flavones of Rhododendra against myocardial ischemia injury

Yi Jiao, Ya‑Nan Li, Zhi‑Wu Chen, Yan Guo
Pages: 3783-3792
Published online on: 13 September 2019

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Article Open Access

Inhibitory effects of genistein in combination with gefitinib on the hepatocellular carcinoma Hep3B cell line

Yongxi Tong, Mingshan Wang, Haijun Huang, Jiajie Zhang, Yicheng Huang, Yingjun Chen, Hongying Pan
Pages: 3793-3800
Published online on: 19 September 2019

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Article Open Access

TAF‑Iβ deficiency inhibits proliferation and promotes apoptosis by rescuing PP2A and inhibiting the AKT/GSK‑3β pathway in leukemic cells

Yanfeng Liu, Yan Jia, Xiao Fu, Pengcheng He
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Smoking cessation affects human platelet activation induced by collagen

Yuko Kito, Mami Iida, Kumiko Tanabe, Takashi Onuma, Masanori Tsujimoto, Kiyoshi Nagase, Haruhiko Tokuda, Toru Iwama, Osamu Kozawa, Hiroki Iida
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Effect of vegetable juice consumption prior to eating rice on postprandial blood glucose and insulin levels

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Clinical relevance of a CD4+ T cell immune function assay in the diagnosis of infection in pediatric living‑donor liver transplantation

Wei Liu, Kai Wang, Yi‑He Zhao, Guang‑Ping Song, Wei Gao, Dai‑Hong Li
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Downregulation of miR‑552 in hepatocellular carcinoma inhibits cell migration and invasion, and promotes cell apoptosis via RUNX3

Ying Ma, Ming Ma, Ling Ma, Fengbo Zhang, Yumei Liu, Xiumin Ma
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Exogenous brain‑derived neurotrophic factor attenuates neuronal apoptosis and neurological deficits after subarachnoid hemorrhage in rats

Huayun Chen, Yanwei Dang, Xiao Liu, Junwei Ren, Hongquan Wang
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Senescent hepatocytes enhance natural killer cell activity via the CXCL‑10/CXCR3 axis

Jinfeng Zang, Jun Ye, Chi Zhang, Min Sha, Junye Gao
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Integrated bioinformatics analysis reveals role of the LINC01093/miR‑96‑5p/ZFAND5/NF‑κB signaling axis in hepatocellular carcinoma

Yahui Zheng, Kangkang Yu, Chong Huang, Lu Liu, Hao Zhao, Meisi Huo, Jubo Zhang
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Effect of ulinastatin combined with mild therapeutic hypothermia on intestinal barrier dysfunction following cardiopulmonary resuscitation in rats

Fang‑Jie Zhang, Hua‑Qiang Song, Xiang‑Min Li
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Outcome prediction for patients with anterior circulation acute ischemic stroke following endovascular treatment: A single‑center study

Xiao Wu, Guoqing Liu, Wu Zhou, Aihua Ou, Xian Liu, Yuhan Wang, Sifan Zhou, Wenting Luo, Bo Liu
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Altered spontaneous brain activity in patients with strabismic amblyopia: A resting‑state fMRI study using regional homogeneity analysis

Xubo Yang, Lu Lu, Qian Li, Xiaoqi Huang, Qiyong Gong, Longqian Liu
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Use of pre‑operative anxiety score to determine the precise dose of butorphanol for intra‑operative sedation under regional anesthesia: A double‑blinded randomized trial

Bijia Song, Yanchao Yang, Xiufei Teng, Yang Li, Wenya Bai, Junchao Zhu
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Safety and efficacy of self‑expandable Evolut R vs. balloon‑expandable Sapien 3 valves for transcatheter aortic valve implantation: A systematic review and meta‑analysis

Chenglin He, Lang Xiao, Junli Liu
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Analysis of the long‑term beneficial effects of menopausal hormone therapy on sleep quality and menopausal symptoms

Caixia Li, Li Wang, Xiaohua Sun, Xiaomei Yang
Pages: 3905-3912
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Homocysteine inhibits the viability and migration ability of human umbilical vein endothelial cells by downregulating the expression of vascular endothelial growth factor

Jian Yu, Ling‑Ling Zhang, Xiao‑Peng Wu, Rui Zhao, Zhi‑Xin Meng, Kun Wang, Bin Wang, Hui Wang, Zuo‑Lei Shi, Guang‑Xin Li
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MicroRNA‑146a protects against intracerebral hemorrhage by inhibiting inflammation and oxidative stress Retraction in /10.3892/etm.2025.12970

Xin Qu, Ning Wang, Weitao Cheng, Yueqiao Xue, Wenjin Chen, Meng Qi
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Mechanism and role of nitric oxide signaling in periodontitis

Yan Wang, Xiangdao Huang, Fuming He
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Inhibition of miRNA‑34a promotes triple negative cancer cell proliferation by promoting glucose uptake

Zhen Li, Xiaoxuan Gong, Wei Zhang, Jian Zhang, Li Ding, Hao Li, Daoyuan Tu, Jinhai Tang
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High lncRNA MEG3 expression is associated with high mortality rates in patients with sepsis and increased lipopolysaccharide‑induced renal epithelial cell and cardiomyocyte apoptosis

Kang Chen, Xiaojun Shi, Ye Jin, Feng Wang, Qing Shen, Weiming Xu
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Exogenous hydrogen sulfide protects against high glucose‑induced apoptosis and oxidative stress by inhibiting the STAT3/HIF‑1α pathway in H9c2 cardiomyocytes Retraction in /10.3892/etm.2024.12479

Jing Li, Yi‑Qiang Yuan, Li Zhang, Hua Zhang, Shen‑Wei Zhang, Yu Zhang, Xue‑Xi Xuan, Ming‑Jie Wang, Jin‑Ying Zhang
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Long non‑coding RNA‑HOTAIR promotes the progression of sepsis by acting as a sponge of miR‑211 to induce IL‑6R expression

Jianan Chen, Xingsheng Gu, Li Zhou, Shuguang Wang, Limei Zhu, Yangneng Huang, Feng Cao
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Differential expression of miR‑4492 and IL‑10 is involved in chronic rhinosinusitis with nasal polyps

Linge Li, Juan Feng, Dinghao Zhang, Jun Yong, Yan Wang, Jianfeng Yao, Rongfu Huang
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Inhibition of growth and migration of cholangiocarcinoma cells by pamidronate

Benjaporn Buranrat, Auemduan Prawan, Laddawan Senggunprai, Veerapol Kukongviriyapan
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Clinicopathological features and prognostic analysis of 49 cases with crescentic glomerulonephritis

Ting Wu, Jiajia Peng, Ting Meng, Qianqian Liu, Xiang Ao, Wei Lin, Hongling Yin, Jinbiao Chen, Jiaxi Pu, Zhangzhe Peng, Weisheng Peng, Xiaozhao Li, Xiangcheng Xiao, Qiaoling Zhou, Yong Zhong, Ping Xiao
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Histological changes in patients who developed hepatocellular carcinoma after hepatitis C virus eradication by interferon‑based therapy

Toshihiro Kawaguchi, Tatsuya Ide, Reiichiro Kondo, Yoriko Nomura, Teruko Arinaga‑Hino, Reiichiro Kuwahara, Keisuke Amano, Tomoya Sano, Jun Akiba, Koichi Ohshima, Hirohisa Yano, Takuji Torimura
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Characterization of DNA hydroxymethylation in the hypothalamus of elderly mice with post‑operative cognitive dysfunction

Jiang Zhong, Wei Xu
Pages: 4002-4010
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Construction of a lncRNA‑miRNA‑mRNA network to determine the regulatory roles of lncRNAs in psoriasis

Qianqian Zhou, Qian Yu, Yu Gong, Zhicui Liu, Hui Xu, Yao Wang, Yuling Shi
Pages: 4011-4021
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Platelet‑derived growth factor‑BB promotes proliferation and migration of retinal microvascular pericytes by up‑regulating the expression of C‑X‑C chemokine receptor types 4

Dan‑Ni Xiang, Yi‑Fan Feng, Jing Wang, Xi Zhang, Jing‑Jing Shen, Rong Zou, Yuan‑Zhi Yuan
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miR‑454‑3p promotes of human glioma cell growth by targeting EGR3

Guoliang Shen, Jian Wu, Zhaohui Mou, Danlong Chen, Li Liu, Xing Li
Pages: 4031-4039
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Low‑frequency ultrasound enhances vascular endothelial growth factor expression, thereby promoting the wound healing in diabetic rats

Lang Chen, Qian Zheng, Xianzhuo Chen, Jun Wang, Lan Wang
Pages: 4040-4048
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MicroRNA‑139‑5p regulates chronic inflammation by suppressing nuclear factor‑κB activity to inhibit cell proliferation and invasion in colorectal cancer

Mingming Zhu, Wen Zhang, Jun Ma, Youguo Dai, Qi Zhang, Qin Liu, Burong Yang, Gang Li
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Role of bile acids in the diagnosis and progression of liver cirrhosis: A prospective observational study

Ning Liu, Jiao Feng, Yang Lv, Qing Liu, Jingfan Deng, Yujing Xia, Chuanyong Guo, Yingqun Zhou
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Increased expression of hub gene CXCL10 in peripheral blood mononuclear cells of patients with systemic lupus erythematosus

Ruixian Zhang, Ya Li, Bangpin Pan, Yi Li, Aimin Liu, Xiaolan Li
Pages: 4067-4075
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Disseminated mucormycosis with cerebellum involvement due to Rhizomucor pusillus in a patient with multiple myeloma and secondary myelodysplastic syndrome: A case report

Qiong Chen, Kuang Chen, Shenxian Qian, Shenghai Wu, Lihui Xu, Xilian Huang, Pengfei Shi, Kaile Wang, Minmin Wang, Xianjun Wang
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Determination of whether supplemental oxygen therapy is beneficial during exercise training in patients with COPD: A systematic review and meta‑analysis

Ying Liu, Fanghua Gong
Pages: 4081-4089
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Modified keyhole technique for the treatment of biceps long head tendon rupture

Yao Huang, Hao Shu, Bing He, Fucheng Zhang, Chunsheng Zhang, Chengjian Peng, Luning Sun
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High serum miR‑484 expression is associated with the diagnosis and prognosis of patients with non‑small cell lung cancer

Zhenli Zhuang, Cuiling Sun, Haitao Gong
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Comprehensive analysis of competing endogenous RNA networks associated with cholangiocarcinoma

Fangting Xu, Yuchong Zhao, Gang Qin, Ye Huan, Longyan Li, Wei Gao
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Necrostatin‑1 ameliorates the pathogenesis of experimental autoimmune encephalomyelitis by suppressing apoptosis and necroptosis of oligodendrocyte precursor cells

Ying Wang, Li Guo, Jueqiong Wang, Wei Shi, Zhilun Xia, Bin Li
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Possible role of BMP‑4 in the hyper‑pigmentation of psoriatic plaques after anti‑TNF‑α treatment

Luisa Di Costanzo, Emanuele Scala, Giuseppina Caiazzo, Serena Lembo, Rita Marino, Matteo Megna, Angela Patrì, Roberta Di Caprio, Anna Balato
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Lidocaine protects H9c2 cells from hypoxia‑induced injury through regulation of the MAPK/ERK/NF‑κB signaling pathway

Haibin Jin, Jin Yu
Pages: 4125-4131
Published online on: 26 September 2019

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Article

Outcome of intra‑articular lumbar facet joint corticosteroid injection according to the severity of facet joint arthritis

Dong Gyu Kwak, Sang Gyu Kwak, Ah Young Lee, Min Cheol Chang
Pages: 4132-4136
Published online on: 20 September 2019

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Article

Salidroside prevents tumor necrosis factor‑α‑induced vascular inflammation by blocking mitogen‑activated protein kinase and NF‑κB signaling activation

Ruoshui Li, Zhen Dong, Xinyu Zhuang, Rongchen Liu, Fangying Yan, Yufei Chen, Xiufang Gao, Haiming Shi
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Treatment of failing arterio‑venous dialysis graft by angioplasty, stent, and stent graft: Two‑years analysis of patency rates and cost‑effectiveness

Jan Kavan, Jaroslav Kudlicka, Jan Malik, Eva Chytilova, Lukas Lambert, Marcela Slavikova, Patrik Matras, Andrea Burgetova
Pages: 4144-4150
Published online on: 25 September 2019

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Failure of initial superselective renal arterial embolization in the treatment of renal hemorrhage after percutaneous nephrolithotomy: A respective analysis of risk factors

Qiqi Mao, Chaojun Wang, Geming Chen, Fuqing Tan, Bohua Shen
Pages: 4151-4156
Published online on: 20 September 2019

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Lipopolysaccharide enhances DNA‑induced IFN‑β expression and autophagy by upregulating cGAS expression in A549 cells

Rong Wang, Wei Wang, Aili Li, Yongqin Wang, Junfei Jin, Zhaoquan Huang, Guojin Huang
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The prognostic performance of Sepsis‑3 and SIRS criteria for patients with urolithiasis‑associated sepsis transferred to ICU following surgical interventions

Bowen Shi, Fei Shi, Ke Xu, Liuhui Shi, Haixiao Tang, Ning Wang, Yanyuan Wu, Jun Gu, Jie Ding, Yunteng Huang
Pages: 4165-4172
Published online on: 26 September 2019

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Correction Open Access

[Corrigendum] Anti‑inflammatory effect of Resolvin D1 on LPS‑treated MG‑63 cells

Dan Cao, Jing Pi, Yihong Shan, Yuping Tang, Ping Zhou
Pages: 4173-4173
Published online on: 18 September 2019

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FCER1G: A multifunctional regulator in the immune microenvironment (Review)

Yuyu Zhang, Jinglan Wang, Wenting He, Tao Liu
Article Number: 146
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A nomogram for predicting recurrence‑free survival in patients with high‑risk GIST receiving adjuvant imatinib: A nationwide registry study

Chun-Nan Yeh, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh, Li-Yaun Bai, Jun-Te Hsu, I-Shu Chen, Li-Tzong Chen, Hui-Jen Tsai, The Taiwan Cooperative Oncology Group Gist Study Group
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[Retracted] MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 144
Published online on: 23 March 2026

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Risk factors for severe retinopathy of prematurity: A retrospective case‑control study

Qingmin Ma, Xi Lv, Jiangya Wang, Kejun Li, Wenwen Τang
Article Number: 143
Published online on: 20 March 2026

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Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial

Dawei Wang, Jingya Dai, Shumei Li, Yaping Liu, Xiaofeng Xing, Lei Huang, Qijun Pang
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Maresin 1 activates autophagy through SIRT1/PPAR‑γ signaling to mitigate high glucose‑induced pyroptosis in human retinal pigment epithelial cells

Jun Zhang, Ding Zhao, Yuanqing Zhang, Haoxiang Sun, Zhipeng Yan, Haiyan Sun
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Advances in new ultrasound technologies in targeted prostate biopsy (Review)

Tingting Jin, Liying Wang, Shusen Zheng
Article Number: 140
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Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review)

Min Liu, Kui Su
Article Number: 139
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Immunohistochemical evaluation of gastric‑type markers in primary extramammary Paget disease: Differential MUC5AC expression between in situ and invasive lesions

Naoto Kohno, Mitsuaki Ishida, Shizuka Ono, Yoshinobu Hirose
Article Number: 138
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Disrupted beginnings: Neurodevelopmental outcomes of COVID‑19 lockdowns in early childhood (Review)

Ioanna Giannopoulou, Vasiliki Efstathiou, Maria-Ioanna Stefanou, Panagiota Korkoliakou, James N. Tsoporis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 137
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[Retracted] Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF‑κB and PI3K/AKT pathways

Ling Sun, Jing Zhang
Article Number: 136
Published online on: 16 March 2026

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Effects of fullerenol C60 on the liver, heart and brain tissues of streptozotocin‑induced diabetic rats with sepsis

Necmiye Şengel, Ömer Kubat, Laman Farajsoylu, Ahmet Çağri Büyükkasap, Muharrem Atli, Şaban Cem Sezen, Hasan Bostanci, Kürşat Dikmen, Işin Güneş, Fatma Er, Mustafa Kavutçu, Mustafa Arslan
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Long non‑coding RNA KCNQ1OT1 promotes ovarian cancer cell malignant characteristics by targeting the miR‑140‑5p/KLK10 axis

Renjie Duan, Zhenyu Tao, Shun Tao, Aichen Yang, Xu Yang, Changzheng Li, Xiaoxiang Zhu, Kexin Zhang, Zhuofu Li, Shanjun Tao
Article Number: 134
Published online on: 11 March 2026

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Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
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Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
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Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
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Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report

Yajun Yao, Ge-Hong Dong, De-Cai Tian
Article Number: 129
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Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta‑analysis

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
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Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Management after two consecutive suction losses during small‑incision lenticule extraction: A case report

Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
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Hematemesis resulting from mesenteric venous thrombosis: A case report

Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
Article Number: 125
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Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
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A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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Factors affecting central sensitization inventory score before surgery for distal radius fractures

Shoichiro Ishii, Kiyohito Naito, Norizumi Imazu, Takamaru Suzuki, Kenjiro Kawamura, So Kawakita, Tatsuki Itoh, Muneaki Ishijima
Article Number: 162
Published online on: 09 April 2026

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Systemic immune‑inflammation index and neutrophil‑to‑lymphocyte ratio predict treatment responses in elderly patients with profound sudden deafness

Chong Li, Huili Wu, Hongxia Cui, Yue Li, Zhiming Sun, Siqi Haoliu, Xinfa Wei
Article Number: 161
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Efficacy analysis of percutaneous cannulated paravertebral approach for microscopic resection of intraspinal schwannomas: A case series

Shaobo Yang, Nianhua Wang
Article Number: 160
Published online on: 09 April 2026

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3D‑printed customized semi‑restrictive elbow prosthesis for severe pseudoarthritis following comminuted fractures of the distal humerus: A case report and review

Bo Zheng, Xiu-Li Zhang, Yu-Xiang Cheng, Ze-Bi He, Peng Li
Article Number: 159
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α‑tocopherol in the prevention of ischemic or hemorrhagic stroke: A meta‑analysis

Peng Xu, Pengfei Cheng
Article Number: 158
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Preliminary study on symptoms and signs of patients with laryngopharyngeal reflux disease infected with Helicobacter pylori

Haixiang Zhang, Huanhuan Dang, Xin Wang, Yuxiang Zhao, Jinping Wang
Article Number: 157
Published online on: 09 April 2026

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Autophagy‑epithelial‑mesenchymal transition crosstalk in acute respiratory distress syndrome: Mechanistic insights and therapeutic perspectives (Review)

Yue Zhang, Hongzhi He, Chufan Dong, Qing Guo, Jiuwen Tan, Yonggui Yang, Zhuangbo Guo, Rui Zhang
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Analysis of low‑benefit subgroups in breast‑conserving surgery: Implications for clinical decision‑making (Review)

Weicheng Lin, Lan Luo, Guiping Guo, Huan Lin
Article Number: 155
Published online on: 08 April 2026

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Plexiform fibromyxoma of the lesser curvature of the stomach in a 16‑year‑old adolescent: A case report and literature review

Zhenhua Fu, Peiyao Tao, Da Sun, Xiang Chen
Article Number: 154
Published online on: 08 April 2026

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Retroperitoneal ovarian venous hemangioma: A case report

Jie Tian, Hong Hu, Siyi Chen, Junping Li
Article Number: 153
Published online on: 08 April 2026

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[Retracted] MicroRNA‑140‑5p regulates the proliferation, apoptosis and inflammation of RA FLSs by repressing STAT3

Jiehua Zhu, Jianglin Wang, Jialin Huang, Wensheng Du, Yingzhong He, Hongfei Pan, Junmin Luo
Article Number: 152
Published online on: 07 April 2026

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Effects of rok1 gene deletion on mitosis in fission yeast at appropriate and stressful temperatures and the molecular mechanisms

Jiayi He, Mengnan Liu, Jiani Xu, Xiang Ding, Yiling Hou
Article Number: 151
Published online on: 02 April 2026

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Therapeutic potential of allicin against viral infections: Mechanisms and safety profile (Review)

Ming-Jun Yu, Yong Zhu, Wei Zhang, Qiao-Ping Xu, Hai-Ming Wang, Zhao Ma
Article Number: 150
Published online on: 02 April 2026

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Interacting proteins of AMPK studied using TurboID proximity labeling technology

Xiaoshan Liu, Jieyu Guo, Qiongyao Wang, Wu Liu, Yan Xue, Shuang Guo, Miao Li
Article Number: 149
Published online on: 02 April 2026

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Multi‑omics analysis of glutamine and fish collagen peptides in alleviating post‑antibiotic Streptococcus pneumoniae injury in feline lung cells

Huasong Bai, Tong Liu, Hengyan Wang, Hongchen Jin, Yunliang Li, Zhanzhong Wang
Article Number: 148
Published online on: 30 March 2026

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[Retracted] MicroRNA‑1236‑3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis

Tingting Meng, Shiman Shen, Cheng Li, Xuehua Liu
Article Number: 147
Published online on: 30 March 2026

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