|
1
|
Joyal JS, Sun Y, Gantner ML, Shao Z, Evans
LP, Saba N, Fredrick T, Burnim S, Kim J, Patel G, et al: Retinal
lipid and glucose metabolism dictates angiogenesis through the
lipid sensor Ffar1. Nat Med. 22:439–445. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ciulla TA, Amador AG and Zinman B:
Diabetic retinopathy and diabetic macular edema: Pathophysiology,
screening, and novel therapies. Diabetes Care. 26:2653–2664. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Zhang M, Chu S, Zeng F and Xu H:
Bevacizumab modulates the process of fibrosis in vitro. Clin Exp
Ophthalmol. 43:173–179. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Amoaku WM, Chakravarthy U, Gale R, Gavin
M, Ghanchi F, Gibson J, Harding S, Johnston RL, Kelly SP, Lotery A,
et al: Defining response to anti-VEGF therapies in neovascular AMD.
Eye (Lond). 29:721–731. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Cao R, Brakenhielm E, Li X, Pietras K,
Widenfalk J, Ostman A, Eriksson U and Cao Y: Angiogenesis
stimulated by PDGF-CC, a novel member in the PDGF family, involves
activation of PDGFR-alphaalpha and -alphabeta receptors. FASEB J.
16:1575–1583. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Hou X, Kumar A, Lee C, Wang B, Arjunan P,
Dong L, Maminishkis A, Tang Z, Li Y, Zhang F, et al: PDGF-CC
blockade inhibits pathological angiogenesis by acting on multiple
cellular and molecular targets. Proc Natl Acad Sci USA.
107:12216–12221. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Park DY, Lee J, Kim J, Kim K, Hong S, Han
S, Kubota Y, Augustin HG, Ding L, Kim JW, et al: Plastic roles of
pericytes in the blood-retinal barrier. Nat Commun. 8:152962017.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Strittmatter K, Pomeroy H and Marneros AG:
Targeting platelet-derived growth factor receptor β(+) scaffold
formation inhibits choroidal neovascularization. Am J Pathol.
186:1890–1899. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Jaffe GJ, Ciulla TA, Ciardella AP, Devin
F, Dugel PU, Eandi CM, Masonson H, Mones J, Pearlman JA,
Quaranta-El Maftouhi M, et al: Dual antagonism of PDGF and VEGF in
neovascular age-related macular degeneration: A phase Iib,
multicenter, randomized controlled trial. Ophthalmology.
124:224–234. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Dunn EN, Hariprasad SM and Sheth VS: An
overview of the fovista and rinucumab trials and the fate of
anti-PDGF medications. Ophthalmic Surg Lasers Imaging Retina.
48:100–104. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Lee E and Rewolinski D: Evaluation of
CXCR4 inhibition in the prevention and intervention model of
laser-induced choroidal neovascularization. Invest Ophthalmol Vis
Sci. 51:3666–3672. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Sengupta N, Caballero S, Mames RN, Timmers
AM, Saban D and Grant MB: Preventing stem cell incorporation into
choroidal neovascularization by targeting homing and attachment
factors. Invest Ophthalmol Vis Sci. 46:343–348. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Feng Y, Wang J, Yuan Y, Zhang X, Shen M
and Yuan F: miR-539-5p inhibits experimental choroidal
neovascularization by targeting CXCR7. Faseb J. 32:1626–1639. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Feng YF, Yuan F, Guo H and Wu WZ: TGF-β1
enhances SDF-1-induced migration and tube formation of
choroid-retinal endothelial cells by up-regulating CXCR4 and CXCR7
expression. Mol Cell Biochem. 397:131–138. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Feng YF, Guo H, Yuan F and Shen MQ:
Lipopolysaccharide promotes choroidal neovascularization by
up-regulation of CXCR4 and CXCR7 expression in choroid endothelial
cell. PLoS One. 10:e01361752015. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Hamdan R, Zhou Z and Kleinerman ES:
Blocking SDF-1α/CXCR4 downregulates PDGF-B and inhibits bone
marrow-derived pericyte differentiation and tumor vascular
expansion in Ewing tumors. Mol Cancer Ther. 13:483–491. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Song N, Huang Y, Shi H, Yuan S, Ding Y,
Song X, Fu Y and Luo Y: Overexpression of platelet-derived growth
factor-BB increases tumor pericyte content via stromal-derived
factor-1alpha/CXCR4 axis. Cancer Res. 69:6057–6064. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Livak K and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Gaceb A, Ozen I, Padel T, Barbariga M and
Paul G: Pericytes secrete pro-regenerative molecules in response to
platelet-derived growth factor-BB. J Cereb Blood Flow Metab.
38:45–57. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Arimura K, Ago T, Kamouchi M, Nakamura K,
Ishitsuka K, Kuroda J, Sugimori H, Ooboshi H, Sasaki T and Kitazono
T: PDGF receptor β signaling in pericytes following ischemic brain
injury. Curr Neurovasc Res. 9:1–9. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Moench R, Grimmig T, Kannen V, Tripathi S,
Faber M, Moll EM, Chandraker A, Lissner R, Germer CT Waaga-Gasser
AM and Gasser M: Exclusive inhibition of PI3K/Akt/mTOR signaling is
not sufficient to prevent PDGF-mediated effects on glycolysis and
proliferation in colorectal cancer. Oncotarget. 7:68749–68767.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Zhang L, Shao J, Zhou Y, Chen H, Qi H,
Wang Y, Chen L, Zhu Y, Zhang M, Chen L, et al: Inhibition of
PDGF-BB-induced proliferation and migration in VSMCs by
proanthocyanidin A2: Involvement of KDR and Jak-2/STAT-3/cPLA2
signaling pathways. Biomed Pharmacother. 98:847–855. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Lim R, Li L, Chew N and Yong EL: The
prenylflavonoid Icaritin enhances osteoblast proliferation and
function by signal transducer and activator of transcription factor
3 (STAT-3) regulation of C-X-C chemokine receptor type 4 (CXCR4)
expression. Bone. 105:122–133. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Liu CH, Wang Z, Sun Y and Chen J: Animal
models of ocular angiogenesis: From development to pathologies.
FASEB J. 31:4665–4681. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Motiejūnaite R and Kazlauskas A: Pericytes
and ocular diseases. Exp Eye Res. 86:171–177. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Genové G, Mollick T and Johansson K:
Photoreceptor degeneration, structural remodeling and glial
activation: A morphological study on a genetic mouse model for
pericyte deficiency. Neuroscience. 279:269–284. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Chantrain CF, Henriet P, Jodele S, Emonard
H, Feron O, Courtoy PJ, DeClerck YA and Marbaix E: Mechanisms of
pericyte recruitment in tumour angiogenesis: A new role for
metalloproteinases. Eur J Cancer. 42:310–318. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Tomkowicz B, Rybinski K, Sebeck D, Sass P,
Nicolaides NC, Grasso L and Zhou Y: Endosialin/TEM-1/CD248
regulates pericyte proliferation through PDGF receptor signaling.
Cancer Biol Ther. 9:908–915. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Yokota J, Chosa N, Sawada S, Okubo N,
Takahashi N, Hasegawa T, Kondo H and Ishisaki A: PDGF-induced
PI3K-mediated signaling enhances the TGF-β-induced osteogenic
differentiation of human mesenchymal stem cells in a
TGF-β-activated MEK-dependent manner. Int J Mol Med. 33:534–542.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Li L, Xu M, Li X, Lv C, Zhang X, Yu H,
Zhang M, Fu Y, Meng H and Zhou J: Platelet-derived growth factor-B
(PDGF-B) induced by hypoxia promotes the survival of pulmonary
arterial endothelial cells through the PI3K/Akt/Stat3 pathway. Cell
Physiol Biochem. 35:441–451. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Lennartsson J, Ma H, Wardega P, Pelka K,
Engstrom U, Hellberg C and Heldin CH: The Fer tyrosine kinase is
important for platelet-derived growth factor-BB-induced signal
transducer and activator of transcription 3 (STAT3) protein
phosphorylation, colony formation in soft agar, and tumor growth in
vivo. J Biol Chem. 288:15736–15744. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Simeone-Penney MC, Severgnini M, Rozo L,
Takahashi S, Cochran BH and Simon AR: PDGF-induced human airway
smooth muscle cell proliferation requires STAT3 and the small
GTPase Rac1. Am J Physiol Lung Cell Mol Physiol. 294:L698–L704.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Vij N, Sharma A, Thakkar M, Sinha S and
Mohan RR: PDGF-driven proliferation, migration, and IL8 chemokine
secretion in human corneal fibroblasts involve JAK2-STAT3 signaling
pathway. Mol Vis. 14:1020–1027. 2008.PubMed/NCBI
|
|
34
|
Furtek SL, Backos DS, Matheson CJ and
Reigan P: Strategies and approaches of targeting STAT3 for cancer
treatment. ACS Chem Biol. 11:308–318. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Lo HW, Hsu SC, Ali-Seyed M, Gunduz M, Xia
W, Wei Y, Bartholomeusz G, Shih JY and Hung MC: Nuclear interaction
of EGFR and STAT3 in the activation of the iNOS/NO pathway. Cancer
Cell. 7:575–589. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Yu YC, Yang PM, Chuah QY, Huang YH, Peng
CW, Lee YJ and Chiu SJ: Radiation-induced senescence in
securin-deficient cancer cells promotes cell invasion involving the
IL-6/STAT3 and PDGF-BB/PDGFR pathways. Sci Rep. 3:16752013.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Levy DE and Darnell JE Jr: Stats:
Transcriptional control and biological impact. Nat Rev Mol Cell
Bio. 3:651–662. 2002. View
Article : Google Scholar
|
|
38
|
Jin J, Zhao WC and Yuan F:
CXCR7/CXCR4/CXCL12 axis regulates the proliferation, migration,
survival and tube formation of choroid-retinal endothelial cells.
Ophthalmic Res. 50:6–12. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Zhao Z, Ma X, Ma J, Sun X, Li F and Lv J:
Naringin enhances endothelial progenitor cell (EPC) proliferation
and tube formation capacity through the CXCL12/CXCR4/PI3K/Akt
signaling pathway. Chem Biol Interact. 286:45–51. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Bialopiotrowicz E, Gorniak P,
Noyszewska-Kania M, Pula B, Makuch-Lasica H, Nowak G, Bluszcz A,
Szydlowski M, Jabłonska E, Piechna K, et al:
Microenvironment-induced PIM kinases promote CXCR4-triggered mTOR
pathway required for chronic lymphocytic leukaemia cell migration.
J Cell Mol Med. 22:3548–3559. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Burns JM, Summers BC, Wang Y, Melikian A,
Berahovich R, Miao Z, Penfold ME, Sunshine MJ, Littman DR, Kuo CJ,
et al: A novel chemokine receptor for SDF-1 and I-TAC involved in
cell survival, cell adhesion, and tumor development. J Exp Med.
203:2201–2213. 2006. View Article : Google Scholar : PubMed/NCBI
|
