Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
December-2019 Volume 18 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
December-2019 Volume 18 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Gastroprotective activity and pharmacological safety evaluation of Eupatorium aschenbornianum

  • Authors:
    • José Miguel Flores‑Fernández
    • Eduardo Padilla‑Camberos
    • Ofelia Fernández‑Flores
    • Nestor Emmanuel Diaz‑Martínez
    • Carla Patricia Barragán‑Álvarez
    • Patricia Berenice Ramírez‑Rodríguez
  • View Affiliations / Copyright

    Affiliations: División de Ingeniería en Industrias Alimentarias e Innovación Agrícola Sustentable, Tecnológico de Estudios Superiores de Villa Guerrero, Carretera Toluca‑Ixtapan de la Sal, Villa Guerrero, Estado de México 51760, México, Unidad de Biotecnología Médica y Farmacéutica, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, Guadalajara, Jalisco 44270, México
  • Pages: 4467-4472
    |
    Published online on: October 10, 2019
       https://doi.org/10.3892/etm.2019.8093
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Eupatorium aschenbornianum has been widely used in traditional Mexican and folk medicine for the treatment of wounds, skin lesions, hemorrhages and gastric ulcers in humans. Phytochemical studies have indicated that hexane extracts of E. aschenbornianum have anti‑microbial and anti‑fungal activities. In the present study, an accurate and reliable approach using a murine model was pursued to evaluate the anti‑ulcer activity, lipid peroxidation properties and acute toxicity of powdered dried stem of E. aschenbornianum. The results indicated that administration of E. aschenbornianum exerted an anti‑ulcerative effect and decreased lipid peroxidation in gastric ulcers induced by acetylsalicylic acid. An acute toxicity assay indicated normal behavior and no significant variations in the weight and food consumption of animals. In addition, quantitative analysis of biochemical parameters did not indicate any liver or kidney damage. The results indicated that E. aschenbornianum may be a safe therapeutic agent for the prevention of gastric ulcers.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Badillo LMD, Espinosa-Madrigal RM, Martínez-Muñoz RE, Ron-Echeverría OA, Salgado-Garciglia R, Flores-García A, Gonzalez DR and Pacheco MMM: The Mexican medicinal plants with antifungal properties are an economic and health opportunity area. Pharmacologyonline. 3:61–77. 2008.

2 

Palma-Tenango M, Miguel-Chávez RS and Soto-Hernández RM: Aromatic and medicinal plants in Mexico, aromatic and medicinal plants Hany El-ShemyIntechOpen; 2017

3 

Alonso-Castro AJ, Domínguez F, Maldonado-Miranda JJ, Castillo-Pérez LJ, Carranza-Álvarez C, Solano E, Isiordia-Espinoza MA, Del Carmen Juárez-Vázquez M, Zapata-Morales JR, Argueta-Fuertes MA, et al: Use of medicinal plants by health professionals in Mexico. J Ethnopharmacol. 198:81–86. 2017. View Article : Google Scholar : PubMed/NCBI

4 

Sobrinho ACN, de Souza EB, Rocha MFG, Albuquerque MRJR, Bandera PN, dos Santos HS, Morais SM, Raquel ODS and Carolina SPC: Cytotoxicity, antifungal and antioxidant activities of the essential oil from Eupatorium ballotifolium Kunth (Asteraceae). Afr J Pharm Pharmacol. 10:346–355. 2016. View Article : Google Scholar

5 

Heinrich M, Frei Haller B and Leonti M: A perspective on natural products research and ethnopharmacology in Mexico: The eagle and the serpent on the prickly pear cactus. J Nat Prod. 77:678–689. 2014. View Article : Google Scholar : PubMed/NCBI

6 

Madaleno IM: A comparative study of medicinal plant cultivation and uses in six Latin American cities. Adv Environ Biol. 5:307–314. 2011.

7 

Sánchez-Mendoza ME, Reyes-Trejo B, Sánchez-Gómez P, Rodríguez-Silverio J, Castillo-Henkel C, Cervantes-Cuevas H and Arrieta J: Bioassay-guided isolation of an anti-ulcer chromene from Eupatorium aschenbornianum: Role of nitric oxide, prostaglandins and sulfydryls. Fitoterapia. 81:66–71. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Navarro García VM, Gonzalez A, Fuentes M, Aviles M, Rios MY, Zepeda G and Rojas MG: Antifungal activities of nine traditional Mexican medicinal plants. J Ethnopharmacol. 87:85–88. 2003. View Article : Google Scholar : PubMed/NCBI

9 

Rios MY, Aguilar-Guadarrama AB and Navarro V: Two new benzofuranes from Eupatorium aschenbornianum and their antimicrobial activity. Planta Med. 69:967–970. 2003. View Article : Google Scholar : PubMed/NCBI

10 

Garcia S, Lopez R, Torres R and Pacheco M: A revision of Eupatorium (Compositae omEupatorieae) from Michoacan. Phyton (B Aires). 80:139–146. 2011.

11 

Liu PY, Liu D, Li WH, Zhao T, Sauriol F, Gu YC, Shi QW and Zhang ML: Chemical Constituents of Plants from the Genus Eupatorium (1904–2014). Chem Biodivers. 12:1481–1515. 2015. View Article : Google Scholar : PubMed/NCBI

12 

Zhang ML, Wu M, Zhang JJ, Irwin D, Gu YC and Shi QW: Chemical constituents of plants from the genus Eupatorium. Chem Biodivers. 5:40–55. 2008. View Article : Google Scholar : PubMed/NCBI

13 

Lanas A and Chan FKL: Peptic ulcer disease. Lancet. 390:613–624. 2017. View Article : Google Scholar : PubMed/NCBI

14 

Ford AC, Gurusamy KS, Delaney B, Forman D and Moayyedi P: Eradication therapy for peptic ulcer disease in Helicobacter pylori-positive people. Cochrane Database Syst Rev. 4:CD0038402016.PubMed/NCBI

15 

Boeing T, da Silva LM, Somensi LB, Cury BJ, Michels Costa AP, Petreanu M, Niero R and de Andrade SF: Antiulcer mechanisms of Vernonia condensata Baker: A medicinal plant used in the treatment of gastritis and gastric ulcer. J Ethnopharmacol. 184:196–207. 2016. View Article : Google Scholar : PubMed/NCBI

16 

Cárdenas-Mondragón MG, Torres J, Flores-Luna L, Carreón-Talavera R, Camorlinga-Ponce M and Fuentes-Pananá EM: Epstein-Barr virus association with peptic ulcer disease. Anal Cell Pathol (Amst). 2015:1648402015.PubMed/NCBI

17 

Paguigan ND, Castillo DH and Chichioco-Hernandez CL: Anti-ulcer activity of leguminosae plants. Arq Gastroenterol. 51:64–67. 2014. View Article : Google Scholar : PubMed/NCBI

18 

Toma W, Gracioso Jde S, de Andrade FD, Hiruma-Lima CA, Vilegas W and Souza Brito AR: Antiulcerogenic activity of four extracts obtained from the bark wood of Quassia amara L. (Simaroubaceae). Biol Pharm Bull. 25:1151–1155. 2002. View Article : Google Scholar : PubMed/NCBI

19 

Tsamakidis K, Panotopoulou E, Dimitroulopoulos D, Xinopoulos D, Christodoulou M, Papadokostopoulou A, Karagiannis I, Kouroumalis E and Paraskevas E: Herpes simplex virus type 1 in peptic ulcer disease: An inverse association with Helicobacter pylori. World J Gastroenterol. 11:6644–6649. 2005. View Article : Google Scholar : PubMed/NCBI

20 

Panda VS and Khambat PD: Antiulcer activity of Garcinia indica fruit rind (kokum berry) in rats. Biomed Aging Pathol. 4:309–316. 2014. View Article : Google Scholar

21 

Yuet Ping K, Darah I, Chen Y, Sreeramanan S and Sasidharan S: Acute and subchronic toxicity study of Euphorbia hirta L. methanol extract in rats. BioMed Res Int. 2013:1820642013. View Article : Google Scholar : PubMed/NCBI

22 

Padilla-Camberos E, Fernández-Flores O, Canales-Aguirre A and Flores-Fernández JM: Subchronic toxicological evaluation of Eupatorium Aschenbornianum in wistar rats. IOSR J Environ Sci. 10:1–3. 2016.

23 

Wang Y, Huang S, Wang Z, Chen F, Chen P, Zhao X, Lin H, Ge R, Zirkin B and Chen H: Long-term maintenance of luteinizing hormone-responsive testosterone formation by primary rat Leydig cells in vitro. Mol Cell Endocrinol. 476:48–56. 2018. View Article : Google Scholar : PubMed/NCBI

24 

Konturek SJ, Brzozowski T, Drozdowicz D and Beck G: Role of leukotrienes in acute gastric lesions induced by ethanol, taurocholate, aspirin, platelet-activating factor and stress in rats. Dig Dis Sci. 33:806–813. 1988. View Article : Google Scholar : PubMed/NCBI

25 

Lewis DA and Shaw GP: A natural flavonoid and synthetic analogues protect the gastric mucosa from aspirin-induced erosions. J Nutr Biochem. 12:95–100. 2001. View Article : Google Scholar : PubMed/NCBI

26 

Narayan S, Devi RS, Jainu M, Sabitha KE and Shyamala Devi CS: Protective effect of a polyherbal drug, ambrex in ethanolinduced gastric mucosal lesions in experimental rats. Indian J Pharmacol. 36:34–37. 2004.

27 

Ajaikumar KB, Asheef M, Babu BH and Padikkala J: The inhibition of gastric mucosal injury by Punicagranatum L. (pomegranate) methanolic extract. J Ethnopharmacol. 96:171–176. 2005. View Article : Google Scholar : PubMed/NCBI

28 

Main IH and Whittle BJ: Investigation of the vasodilator and antisecretory role of prostaglandins in the rat gastric mucosa by use of non-steroidal anti-inflammatory drugs. Br J Pharmacol. 53:217–224. 1975. View Article : Google Scholar : PubMed/NCBI

29 

OECD, . 425: Acute oral toxicity: Up-and-down procedure. OECD Guidelines for the testing of chemicalsParis: OECD Publishing; 2008

30 

Jendrassik L and Grof P: Vereinfachte photo-metrische Methoden zur Bestimmung des Blutbilirubins. Biochemische Z Band. 297:81–89. 1938.

31 

Reitman S and Frankel S: A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am J Clin Pathol. 28:56–63. 1957. View Article : Google Scholar : PubMed/NCBI

32 

Doumas BT, Watson WA and Biggs HG: Albumin standards and the measurement of serum albumin with bromcresol green. 1971. Clin Chim Acta. 31:87–96. 1977. View Article : Google Scholar

33 

Bessey OA, Lowry OH and Brock MJ: A method for the rapid determination of alkaline phosphates with five cubic millimeters of serum. J Biol Chem. 164:321–329. 1946.PubMed/NCBI

34 

Giknis M and Clifford C: Clinical laboratory parameters for Crl:WI(Han) rats. Accel Drug Dev. 1–14. 2008.

35 

El-Shinnawy NA, Abd-Elmageid SA and Alshailabi EM: Evaluation of antiulcer activity of indole-3-carbinol and/or omeprazole on aspirin-induced gastric ulcer in rats. Toxicol Ind Health. 30:357–375. 2014. View Article : Google Scholar : PubMed/NCBI

36 

Jainu M and Devi CS: Effect of ambrex (an amber based formulation) on gastric mucosal damage: Role of antioxidant enzymes and lipid profile. Indian J Physiol Pharmacol. 48:343–347. 2004.PubMed/NCBI

37 

Tuluce Y, Ozkol H, Koyuncu I and Ine H: Gastroprotective effect of small centaury (Centaurium erythraea L) on aspirin-induced gastric damage in rats. Toxicol Ind Health. 27:760–768. 2011. View Article : Google Scholar : PubMed/NCBI

38 

Jain P: Secondary metabolites for antiulcer activity. Nat Prod Res. 30:640–656. 2016. View Article : Google Scholar : PubMed/NCBI

39 

Krishnan M, Jayaraj RL, Megala J and Elangovan N: Antioxidant mediated antiulcer effect of Eupatorium triplinerve Vahl against acetic acid induced ulcerative colitis in mice. Biomed Aging Pathol. 4:153–160. 2014. View Article : Google Scholar

40 

Das SK and Roy C: The protective role of Aegle marmelos on aspirin-induced gastro-duodenal ulceration in albino rat model: A possible involvement of antioxidants. Saudi J Gastroenterol. 18:188–194. 2012. View Article : Google Scholar : PubMed/NCBI

41 

Firenzuoli F and Gori L: Herbal medicine today: Clinical and research issues. Evid Based Complement Alternat Med. 4 (Suppl 1):S37–S40. 2007. View Article : Google Scholar

42 

Santos SR, Rangel ET, Lima JC, Silva RM, Lopes L, Noldin VF, Cechinel Filho V, Delle Monache F and Martins DT: Toxicological and pheytochemical studies of Aspidosperma subincanum Mart. stem bark (Guatambu). Pharmazie. 64:836–839. 2009.PubMed/NCBI

43 

Gowda S, Desai PB, Hull VV, Math AA, Vernekar SN and Kulkarni SS: A review on laboratory liver function tests. Pan Afr Med J. 3:172009.PubMed/NCBI

44 

Wang L, Li Z, Li L, Li Y, Yu M, Zhou Y, Lv X, Arai H and Xu Y: Acute and sub-chronic oral toxicity profiles of the aqueous extract of Cortex Dictamni in mice and rats. J Ethnopharmacol. 158:207–215. 2014. View Article : Google Scholar : PubMed/NCBI

45 

Adeyemo-Salami OA and Makinde JM: Acute and sub-acute toxicity studies of the methanol extract of the leaves of Paullinia pinnata (Linn.) in Wistar albino mice and rats. Afr J Med Med Sci. 42:81–90. 2013.PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Flores‑Fernández JM, Padilla‑Camberos E, Fernández‑Flores O, Diaz‑Martínez NE, Barragán‑Álvarez CP and Ramírez‑Rodríguez PB: Gastroprotective activity and pharmacological safety evaluation of Eupatorium aschenbornianum. Exp Ther Med 18: 4467-4472, 2019.
APA
Flores‑Fernández, J.M., Padilla‑Camberos, E., Fernández‑Flores, O., Diaz‑Martínez, N.E., Barragán‑Álvarez, C.P., & Ramírez‑Rodríguez, P.B. (2019). Gastroprotective activity and pharmacological safety evaluation of Eupatorium aschenbornianum. Experimental and Therapeutic Medicine, 18, 4467-4472. https://doi.org/10.3892/etm.2019.8093
MLA
Flores‑Fernández, J. M., Padilla‑Camberos, E., Fernández‑Flores, O., Diaz‑Martínez, N. E., Barragán‑Álvarez, C. P., Ramírez‑Rodríguez, P. B."Gastroprotective activity and pharmacological safety evaluation of Eupatorium aschenbornianum". Experimental and Therapeutic Medicine 18.6 (2019): 4467-4472.
Chicago
Flores‑Fernández, J. M., Padilla‑Camberos, E., Fernández‑Flores, O., Diaz‑Martínez, N. E., Barragán‑Álvarez, C. P., Ramírez‑Rodríguez, P. B."Gastroprotective activity and pharmacological safety evaluation of Eupatorium aschenbornianum". Experimental and Therapeutic Medicine 18, no. 6 (2019): 4467-4472. https://doi.org/10.3892/etm.2019.8093
Copy and paste a formatted citation
x
Spandidos Publications style
Flores‑Fernández JM, Padilla‑Camberos E, Fernández‑Flores O, Diaz‑Martínez NE, Barragán‑Álvarez CP and Ramírez‑Rodríguez PB: Gastroprotective activity and pharmacological safety evaluation of Eupatorium aschenbornianum. Exp Ther Med 18: 4467-4472, 2019.
APA
Flores‑Fernández, J.M., Padilla‑Camberos, E., Fernández‑Flores, O., Diaz‑Martínez, N.E., Barragán‑Álvarez, C.P., & Ramírez‑Rodríguez, P.B. (2019). Gastroprotective activity and pharmacological safety evaluation of Eupatorium aschenbornianum. Experimental and Therapeutic Medicine, 18, 4467-4472. https://doi.org/10.3892/etm.2019.8093
MLA
Flores‑Fernández, J. M., Padilla‑Camberos, E., Fernández‑Flores, O., Diaz‑Martínez, N. E., Barragán‑Álvarez, C. P., Ramírez‑Rodríguez, P. B."Gastroprotective activity and pharmacological safety evaluation of Eupatorium aschenbornianum". Experimental and Therapeutic Medicine 18.6 (2019): 4467-4472.
Chicago
Flores‑Fernández, J. M., Padilla‑Camberos, E., Fernández‑Flores, O., Diaz‑Martínez, N. E., Barragán‑Álvarez, C. P., Ramírez‑Rodríguez, P. B."Gastroprotective activity and pharmacological safety evaluation of Eupatorium aschenbornianum". Experimental and Therapeutic Medicine 18, no. 6 (2019): 4467-4472. https://doi.org/10.3892/etm.2019.8093
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team