|
1
|
Glyn-Jones S, Palmer AJ, Agricola R, Price
AJ, Vincent TL, Weinans H and Carr AJ: Osteoarthritis. Lancet.
386:376–387. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Scanzello CR and Goldring SR: The role of
synovitis in osteoarthritis pathogenesis. Bone. 51:249–257. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Kapoor M, Martel-Pelletier J, Lajeunesse
D, Pelletier JP and Fahmi H: Role of proinflammatory cytokines in
the pathophysiology of osteoarthritis. Nat Rev Rheumatol. 7:33–42.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Robinson WH, Lepus CM, Wang Q, Raghu H,
Mao R, Lindstrom TM and Sokolove J: Low-grade inflammation as a key
mediator of the pathogenesis of osteoarthritis. Nat Rev Rheumatol.
12:580–592. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Del Rey MJ, Usategui A, Izquierdo E,
Cañete JD, Blanco FJ, Criado G and Pablos JL: Transcriptome
analysis reveals specific changes in osteoarthritis synovial
fibroblasts. Ann Rheum Dis. 71:275–280. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Lee CS, Buttitta L and Fan CM: Evidence
that the WNT-inducible growth arrest-specific gene 1 encodes an
antagonist of sonic hedgehog signaling in the somite. Proc Natl
Acad Sci USA. 98:11347–11352. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Schneider C, King RM and Philipson L:
Genes specifically expressed at growth arrest of mammalian cells.
Cell. 54:787–793. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Benitez JA, Arregui L, Vergara P and
Segovia J: Targeted-simultaneous expression of Gas1 and p53 using a
bicistronic adenoviral vector in gliomas. Cancer Gene Ther.
14:836–846. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Jiménez A, López-Ornelas A, Estudillo E,
González-Mariscal L, González RO and Segovia J: A soluble form of
GAS1 inhibits tumor growth and angiogenesis in a triple negative
breast cancer model. Exp Cell Res. 327:307–317. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Evdokiou A and Cowled PA:
Tumor-suppressive activity of the growth arrest-specific gene GAS1
in human tumor cell lines. Int J Cancer. 75:568–577. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Wang H, Zhou X, Zhang Y, Zhu H, Zhao L,
Fan L, Wang Y, Gang Y, Wu K, Liu Z and Fan D: Growth
arrest-specific gene 1 is downregulated and inhibits tumor growth
in gastric cancer. FEBS J. 279:3652–3664. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Jiang Z, Xu Y and Cai S: Down-regulated
GAS1 expression correlates with recurrence in stage II and III
colorectal cancer. Hum Pathol. 42:361–368. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Zamorano A, Lamas M, Vergara P, Naranjo JR
and Segovia J: Transcriptionally mediated gene targeting of gas1 to
glioma cells elicits growth arrest and apoptosis. J Neurosci Res.
71:256–263. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Cabrera JR, Sanchez-Pulido L, Rojas AM,
Valencia A, Mañes S, Naranjo JR and Mellström B: Gas1 is related to
the glial cell-derived neurotrophic factor family receptors alpha
and regulates Ret signaling. J Biol Chem. 281:14330–14339. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Ma Y, Qin H and Cui Y: MiR-34a targets
GAS1 to promote cell proliferation and inhibit apoptosis in
papillary thyroid carcinoma via PI3K/Akt/Bad pathway. Biochem
Biophys Res Commun. 441:958–963. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Bartel DP: MicroRNAs: Genomics,
biogenesis, mechanism, and function. Cell. 116:281–297. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Urbich C, Kuehbacher A and Dimmeler S:
Role of microRNAs in vascular diseases, inflammation, and
angiogenesis. Cardiovasc Res. 79:581–588. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Stanczyk J, Pedrioli DM, Brentano F,
Sanchez-Pernaute O, Kolling C, Gay RE, Detmar M, Gay S and Kyburz
D: Altered expression of MicroRNA in synovial fibroblasts and
synovial tissue in rheumatoid arthritis. Arthritis Rheum.
58:1001–1009. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Nakamachi Y, Kawano S, Takenokuchi M,
Nishimura K, Sakai Y, Chin T, Saura R, Kurosaka M and Kumagai S:
MicroRNA-124a is a key regulator of proliferation and monocyte
chemoattractant protein 1 secretion in fibroblast-like synoviocytes
from patients with rheumatoid arthritis. Arthritis Rheum.
60:1294–1304. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Gao J, Zhou XL, Kong RN, Ji LM, He LL and
Zhao DB: microRNA-126 targeting PIK3R2 promotes rheumatoid
arthritis synovial fibro-blasts proliferation and resistance to
apoptosis by regulating PI3K/AKT pathway. Exp Mol Pathol.
100:192–198. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Li YH, Tavallaee G, Tokar T, Nakamura A,
Sundararajan K, Weston A, Sharma A, Mahomed NN, Gandhi R, Jurisica
I and Kapoor M: Identification of synovial fluid microRNA signature
in knee osteoarthritis: Differentiating early- and late-stage knee
osteoarthritis. Osteoarthritis Cartilage. 24:1577–1586. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Murata K, Yoshitomi H, Tanida S, Ishikawa
M, Nishitani K, Ito H and Nakamura T: Plasma and synovial fluid
microRNAs as potential biomarkers of rheumatoid arthritis and
osteoarthritis. Arthritis Res Ther. 12:R862010. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kung LHW, Ravi V, Rowley L, Bell KM,
Little CB and Bateman JF: Comprehensive expression analysis of
microRNAs and mRNAs in synovial tissue from a mouse model of early
post-traumatic osteoarthritis. Sci Rep. 7:177012017. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Inoue H, Takamori M, Nagata N, Nishikawa
T, Oda H, Yamamoto S and Koshihara Y: An investigation of cell
proliferation and soluble mediators induced by interleukin 1beta in
human synovial fibroblasts: Comparative response in osteoarthritis
and rheumatoid arthritis. Inflamm Res. 50:65–72. 2001.PubMed/NCBI
|
|
26
|
Li L, Ittmann MM, Ayala G, Tsai MJ, Amato
RJ, Wheeler TM, Miles BJ, Kadmon D and Thompson TC: The emerging
role of the PI3-K-Akt pathway in prostate cancer progression.
Prostate Cancer Prostatic Dis. 8:108–118. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Sarris EG, Saif MW and Syrigos KN: The
biological role of PI3K pathway in lung cancer. Pharmaceuticals.
5:1236–1264. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Feng Y, Qian W, Zhang Y, Peng W, Li J, Gu
Q, Ji D, Zhang Z, Wang Q, Zhang D and Sun Y: CDCA2 promotes the
proliferation of colorectal cancer cells by activating the
AKT/CCND1 pathway in vitro and in vivo. BMC Cancer. 19:5762019.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Oehler S, Neureiter D, Meyer-Scholten C
and Aigner T: Subtyping of osteoarthritic synoviopathy. Clin Exp
Rheumatol. 20:633–640. 2002.PubMed/NCBI
|
|
30
|
Ayral X, Pickering EH, Woodworth TG,
Mackillop N and Dougados M: Synovitis: A potential predictive
factor of structural progression of medial tibiofemoral knee
osteoarthritis-results of a 1 year longitudinal arthroscopic study
in 422 patients. Osteoarthritis Cartilage. 13:361–367. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Sieghart D, Liszt M, Wanivenhaus A, Bröll
H, Kiener H, Klösch B and Steiner G: Hydrogen sulphide decreases
IL-1β-induced activation of fibroblast-like synoviocytes from
patients with osteoarthritis. J Cell Mol Med. 19:187–197. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Eymard F, Pigenet A, Citadelle D,
Flouzat-Lachaniette CH, Poignard A, Benelli C, Berenbaum F,
Chevalier X and Houard X: Induction of an inflammatory and
prodegradative phenotype in autologous fibroblast-like synoviocytes
by the infrapatellar fat pad from patients with knee
osteoarthritis. Arthritis Rheumatol. 66:2165–2174. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Del Sal G, Ruaro EM, Utrera R, Cole CN,
Levine AJ and Schneider C: Gas1-induced growth suppression requires
a transactivation-independent p53 function. Mol Cell Biol.
15:7152–7160. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Huang Y, Prasad M, Lemon WJ, Hampel H,
Wright FA, Kornacker K, LiVolsi V, Frankel W, Kloos RT, Eng C, et
al: Gene expression in papillary thyroid carcinoma reveals highly
consistent profiles. Proc Natl Acad Sci USA. 98:15044–15049. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Moriarty HT and Webster LR: Fragile sites
and bladder cancer. Cancer Genet Cytogenet. 140:89–98. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Konstantinova LN, Fleischman EW, Knisch
VI, Perevozchikov AG and Kopnin BP: Karyotype peculiarities of
human colorectal adenocarcinomas. Hum Genet. 86:491–496. 1991.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Lee TC, Li L, Philipson L and Ziff EB: Myc
represses transcription of the growth arrest gene gas1. Proc Natl
Acad Sci USA. 94:12886–12891. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Zhao L, Pan Y, Gang Y, Wang H, Jin H, Tie
J, Xia L, Zhang Y, He L, Yao L, et al: Identification of GAS1 as an
epirubicin resistance-related gene in human gastric cancer cells
with a partially randomized small interfering RNA library. J Biol
Chem. 284:26273–26285. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Spagnuolo R, Corada M, Orsenigo F, Zanetta
L, Deuschle U, Sandy P, Schneider C, Drake CJ, Breviario F and
Dejana E: Gas1 is induced by VE-cadherin and vascular endothelial
growth factor and inhibits endothelial cell apoptosis. Blood.
103:3005–3012. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Airaksinen MS, Holm L and Hätinen T:
Evolution of the GDNF family ligands and receptors. Brain Behav
Evol. 68:181–190. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Hayer S, Pundt N, Peters MA, Wunrau C,
Kühnel I, Neugebauer K, Strietholt S, Zwerina J, Korb A, Penninger
J, et al: PI3Kgamma regulates cartilage damage in chronic
inflammatory arthritis. FASEB J. 23:4288–4298. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Mograbi B, Bocciardi R, Bourget I, Busca
R, Rochet N, Farahi-Far D, Juhel T and Rossi B: Glial cell
line-derived neurotrophic factor-stimulated phosphatidylinositol
3-kinase and Akt activities exert opposing effects on the ERK
pathway: Importance for the rescue of neuroectodermic cells. J Biol
Chem. 276:45307–45319. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Zhou Y, Ding BZ, Lin YP and Wang HB:
MiR-34a, as a suppressor, enhance the susceptibility of gastric
cancer cell to luteolin by directly targeting HK1. Gene. 644:56–65.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Li T, Li L, Li D, Wang S and Sun J:
MiR-34a inhibits oral cancer progression partially by repression of
interleukin-6-receptor. Int J Clin Exp Pathol. 8:1364–1373.
2015.PubMed/NCBI
|
|
45
|
Zhao J, Guerrero A, Kelnar K, Peltier HJ
and Bader AG: Synergy between next generation EGFR tyrosine kinase
inhibitors and miR-34a in the inhibition of non-small cell lung
cancer. Lung Cancer. 108:96–102. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Shi H, Zhou S, Liu J, Zhu J, Xue J, Gu L
and Chen Y: miR-34a inhibits the in vitro cell proliferation and
migration in human esophageal cancer. Pathol Res Pract.
212:444–449. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Yan S, Wang M, Zhao J, Zhang H, Zhou C,
Jin L, Zhang Y, Qiu X, Ma B and Fan Q: MicroRNA-34a affects
chondrocyte apoptosis and proliferation by targeting the SIRT1/p53
signaling pathway during the pathogenesis of osteoarthritis. Int J
Mol Med. 38:201–209. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Yang B, Ni J, Long H, Huang J, Yang C and
Huang X: IL-1β-induced miR-34a up-regulation inhibits Cyr61 to
modulate osteoarthritis chondrocyte proliferation through ADAMTS-4.
J Cell Biochem. 119:7959–7970. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Zhang W, Hsu P, Zhong B, Guo S and Zhang
C, Wang Y, Luo C, Zhan Y and Zhang C: MiR-34a enhances chondrocyte
apoptosis, senescence and facilitates development of osteoarthritis
by targeting DLL1 and regulating PI3K/AKT pathway. Cell Physiol
Biochem. 48:1304–1316. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Zhang L, He X, Li F, Pan H, Huang X, Wen
X, Zhang H, Li B, Ge S, Xu X, et al: The miR-181 family promotes
cell cycle by targeting CTDSPL, a phosphatase-like tumor suppressor
in uveal melanoma. J Exp Clin Cancer Res. 37:152018. View Article : Google Scholar : PubMed/NCBI
|
