1
|
Ursu RG, Danciu M, Spiridon IA, Ridder R,
Rehm S, Maffini F, McKay-Chopin S, Carreira C, Lucas E, Costan VV,
et al: Role of mucosal high-risk human papillomavirus types in head
and neck cancers in Romania. PLoS One. 13:e01996632018. View Article : Google Scholar : PubMed/NCBI
|
2
|
Forman D, Bray F, Brewster DH, Gombe
Mbalawa C, Kohler B, Piñeros M, Steliarova-Foucher E, Swaminathan R
and Ferlay J: Cancer Incidence in Five Continents VolX.
International Agency for Research on Cancer; Lyon: 2014
|
3
|
Ferlay J, Shin HR, Bray F, Forman D,
Mathers C and Parkin DM: Estimates of worldwide burden of cancer in
2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar : PubMed/NCBI
|
4
|
Kumar M, Nanavati R, Modi TG and Dobariya
C: Oral cancer: Etiology and risk factors: A review. J Cancer Res
Ther. 12:458–463. 2016. View Article : Google Scholar : PubMed/NCBI
|
5
|
Vigneswaran N and Williams MD:
Epidemiologic trends in head and neck cancer and aids in diagnosis.
Oral Maxillofac Surg Clin North Am. 26:123–141. 2014. View Article : Google Scholar : PubMed/NCBI
|
6
|
Vermorken JB, Remenar E, van Herpen C,
Gorlia T, Mesia R, Degardin M, Stewart JS, Jelic S, Betka J, Preiss
JH, et al EORTC 24971/TAX 323 Study Group, : Cisplatin,
fluorouracil, and docetaxel in unresectable head and neck cancer. N
Engl J Med. 357:1695–1704. 2007. View Article : Google Scholar : PubMed/NCBI
|
7
|
Jimenez L, Jayakar SK, Ow TJ and Segall
JE: Mechanisms of invasion in head and neck cancer. Arch Pathol Lab
Med. 139:1334–1348. 2015. View Article : Google Scholar : PubMed/NCBI
|
8
|
Voiculescu VM, Caruntu C, Solomon I, Lupu
M, Ilie MA, Boda D, Constantin C and Neagu M: Squamous cell
carcinoma: Biomarkers and potential therapeutic targetsHuman Skin
Cancers - Pathways, Mechanisms, Targets and Treatments. Blumenberg
M: IntechOpen; London: pp. 135–159. 2018
|
9
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
10
|
Zhai TT, van Dijk LV, Huang BT, Lin ZX,
Ribeiro CO, Brouwer CL, Oosting SF, Halmos GB, Witjes MJH,
Langendijk JA, et al: Improving the prediction of overall survival
for head and neck cancer patients using image biomarkers in
combination with clinical parameters. Radiother Oncol. 124:256–262.
2017. View Article : Google Scholar : PubMed/NCBI
|
11
|
Lupu M, Caruntu A, Caruntu C, Boda D,
Moraru L, Voiculescu V and Bastian A: Non-invasive imaging of
actinic cheilitis and squamous cell carcinoma of the lip. Mol Clin
Oncol. 8:640–646. 2018.PubMed/NCBI
|
12
|
Boda D, Docea AO, Calina D, Ilie MA,
Caruntu C, Zurac S, Neagu M, Constantin C, Branisteanu DE,
Voiculescu V, et al: Human papilloma virus: Apprehending the link
with carcinogenesis and unveiling new research avenues (Review).
Int J Oncol. 52:637–655. 2018.PubMed/NCBI
|
13
|
Hassan M, Watari H, AbuAlmaaty A, Ohba Y
and Sakuragi N: Apoptosis and molecular targeting therapy in
cancer. BioMed Res Int. 2014:1508452014. View Article : Google Scholar : PubMed/NCBI
|
14
|
Neagu M, Constantin C, Popescu ID, Zipeto
D, Tzanakakis G, Nikitovic D, Fenga C, Stratakis CA, Spandidos DA
and Tsatsakis AM: Inflammation and metabolism in cancer cell -
mitochondria key player. Front Oncol. 9:3482019. View Article : Google Scholar : PubMed/NCBI
|
15
|
Cagnol S and Chambard JC: ERK and cell
death: Mechanisms of ERK-induced cell death - apoptosis, autophagy
and senescence. FEBS J. 277:2–21. 2010. View Article : Google Scholar : PubMed/NCBI
|
16
|
Huang J, Zhang J, Shi C, Liu L and Wei Y:
Survival, recurrence and toxicity of HNSCC in comparison of a
radiotherapy combination with cisplatin versus cetuximab: A
meta-analysis. BMC Cancer. 16:6892016. View Article : Google Scholar : PubMed/NCBI
|
17
|
Neagu M, Caruntu C, Constantin C, Boda D,
Zurac S, Spandidos DA and Tsatsakis AM: Chemically induced skin
carcinogenesis: Updates in experimental models (Review). Oncol Rep.
35:2516–2528. 2016. View Article : Google Scholar : PubMed/NCBI
|
18
|
Kass JI, Moskowitz HS and Grandis JR:
Oncogenomics/Proteomics of Head and Neck Cancers. Head and Neck
CancerMultimodality Management. 2nd. Springer International
Publishing; New York, NY: pp. 101–114. 2016
|
19
|
Chen L and Tweddle DA: p53, SKP2, DKK3 as
MYCN target genes and their potential therapeutic significance.
Cancer Molecular Targets and Therapeutic. Front Oncol. 2:1732012.
View Article : Google Scholar : PubMed/NCBI
|
20
|
Boda D: Cellomics as integrative omics for
cancer. Curr Proteomics. 10:237–245. 2013. View Article : Google Scholar
|
21
|
Powell E, Piwnica-Worms D and
Piwnica-Worms H: Contribution of p53 to metastasis. Cancer Discov.
4:405–414. 2014. View Article : Google Scholar : PubMed/NCBI
|
22
|
Samatar AA and Poulikakos PI: Targeting
RAS-ERK signalling in cancer: Promises and challenges. Nat Rev Drug
Discov. 13:928–942. 2014. View Article : Google Scholar : PubMed/NCBI
|
23
|
Solomon I, Voiculescu VM, Caruntu C, Lupu
M, Popa A, Ilie MA, Albulescu R, Caruntu A, Tanase C, Constantin C,
et al: Neuroendocrine factors and head and neck squamous cell
carcinoma: An affair to remember. Dis Markers. 2018:97878312018.
View Article : Google Scholar : PubMed/NCBI
|
24
|
Yang SH, Sharrocks AD and Whitmarsh AJ:
MAP kinase signalling cascades and transcriptional regulation.
Gene. 513:1–13. 2013. View Article : Google Scholar : PubMed/NCBI
|
25
|
Lupu M, Caruntu A, Caruntu C, Papagheorghe
LM, Ilie MA, Voiculescu V, Boda D, Constantin C, Tanase C, Sifaki
M, et al: Neuroendocrine factors: The missing link in non melanoma
skin cancer (Review). Oncol Rep. 38:1327–1340. 2017. View Article : Google Scholar : PubMed/NCBI
|
26
|
Burotto M, Chiou VL, Lee JM and Kohn EC:
The MAPK pathway across different malignancies: A new perspective.
Cancer. 120:3446–3456. 2014. View Article : Google Scholar : PubMed/NCBI
|
27
|
Urosevic J, Nebreda AR and Gomis RR: MAPK
signaling control of colon cancer metastasis. Cell Cycle.
13:2641–2642. 2014. View Article : Google Scholar : PubMed/NCBI
|
28
|
Tanase CP, Neagu M and Albulescu R: Key
signaling molecules in pituitary tumors. Expert Rev Mol Diagn.
9:859–877. 2009. View Article : Google Scholar : PubMed/NCBI
|
29
|
Yang M and Huang CZ: Mitogen-activated
protein kinase signaling pathway and invasion and metastasis of
gastric cancer. World J Gastroenterol. 21:11673–11679. 2015.
View Article : Google Scholar : PubMed/NCBI
|
30
|
Peng Q, Deng Z, Pan H, Gu L, Liu O and
Tang Z: Mitogen-activated protein kinase signaling pathway in oral
cancer. Oncol Lett. 15:1379–1388. 2018.PubMed/NCBI
|
31
|
Kumari R, Chouhan S, Singh S, Chhipa RR,
Ajay AK and Bhat MK: Constitutively activated ERK sensitizes cancer
cells to doxorubicin: Involvement of p53-EGFR-ERK pathway. J
Biosci. 42:31–41. 2017. View Article : Google Scholar : PubMed/NCBI
|
32
|
Wang J, Luo L, Wang D, Guo B, Li J, Yang Z
and Tang D: Combination adjuvant chemotherapy with targeted drugs
for treatment of colorectal cancer: A network meta-analysis. J Cell
Biochem. 119:1521–1537. 2018. View Article : Google Scholar : PubMed/NCBI
|
33
|
Bailon-Moscoso N, Cevallos-Solorzano G,
Romero-Benavides JC and Orellana MI: Natural compounds as
modulators of cell cycle arrest: Application for anticancer
chemotherapies. Curr Genomics. 18:106–131. 2017. View Article : Google Scholar : PubMed/NCBI
|
34
|
Seca AM and Pinto DC: Plant secondary
metabolites as anticancer agents: Successes in clinical trials and
therapeutic application. Int J Mol Sci. 19:E2632018. View Article : Google Scholar : PubMed/NCBI
|
35
|
Shanmugam MK, Rane G, Kanchi MM, Arfuso F,
Chinnathambi A, Zayed ME, Alharbi SA, Tan BK, Kumar AP and Sethi G:
The multifaceted role of curcumin in cancer prevention and
treatment. Molecules. 20:2728–2769. 2015. View Article : Google Scholar : PubMed/NCBI
|
36
|
Miao Y, Zhao S, Gao Y, Wang R, Wu Q, Wu H
and Luo T: Curcumin pretreatment attenuates inflammation and
mitochondrial dysfunction in experimental stroke: The possible role
of Sirt1 signaling. Brain Res Bull. 121:9–15. 2016. View Article : Google Scholar : PubMed/NCBI
|
37
|
Shi D, Xu Y, Du X, Chen X, Zhang X, Lou J,
Li M and Zhuo J: Co-treatment of THP-1 cells with naringenin and
curcumin induces cell cycle arrest and apoptosis via numerous
pathways. Mol Med Rep. 12:8223–8228. 2015. View Article : Google Scholar : PubMed/NCBI
|
38
|
Patel PB, Thakkar VR and Patel JS:
Cellular effect of curcumin and citral combination on breast cancer
cells: Induction of apoptosis and cell cycle arrest. J Breast
Cancer. 18:225–234. 2015. View Article : Google Scholar : PubMed/NCBI
|
39
|
Neagu M, Constantin C, Tanase C and Boda
D: Patented biomarker panels in early detection of cancer. Recent
Pat Biomark. 1:10–24. 2011. View Article : Google Scholar
|
40
|
Chen XY, Cai HZ, Wang XY, Chen QY, Yang H,
Chen YJ and Tang YP: Application of the ERK signaling pathway
inhibitor PD98059 in long-term in vivo experiments. Genet Mol Res.
14:18325–33. 2015. View Article : Google Scholar : PubMed/NCBI
|
41
|
Barltrop JA, Owen TC, Cory AH and Cory JG:
5-(3-carboxymethoxyphenyl)-2-(4,5-dimenthylthiazoly)-3-(4-sulfophenyl)tetrazolium,
inner salt (MTS) and related analogs of
3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium bromide (MTT)
reducing to purple water-soluble formazans as cell-viability
indicators. Bioorg Med Chem Lett. 1:611–614. 1991. View Article : Google Scholar
|
42
|
Petrică-Matei GG, Iordache F, Hainăroşie R
and Bostan M: Characterization of the tumor cells from human head
and neck cancer. Rom J Morphol Embryol. 57 (Suppl 2):791–799.
2016.PubMed/NCBI
|
43
|
Hirshberg A, Yarom N, Amariglio N, Yahalom
R, Adam I, Stanchescu R, Ben-Dov I, Taicher S, Rechavi G and
Trakhtenbrot L: Detection of non-diploid cells in premalignant and
malignant oral lesions using combined morphological and FISH
analysis - a new method for early detection of suspicious oral
lesions. Cancer Lett. 253:282–290. 2007. View Article : Google Scholar : PubMed/NCBI
|
44
|
Salido M, Tusquets I, Corominas JM, Suarez
M, Espinet B, Corzo C, Bellet M, Fabregat X, Serrano S and Solé F:
Genetic alterations of chromosome 17 in human breast carcinoma
studied by fluorescence in situ hybridization and molecular DNA
techniques. Breast Cancer Res. 7:267–273. 2005. View Article : Google Scholar
|
45
|
Sunahori K, Nagpal K, Hedrich CM, Mizui M,
Fitzgerald LM and Tsokos GC: The catalytic subunit of protein
phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing
the phosphorylated mitogen-activated protein kinase/extracellular
signal-regulated kinase (ERK) kinase (MEK)/phosphorylated ERK/DNMT1
protein pathway in T-cells from controls and systemic lupus
erythematosus patients. J Biol Chem. 288:21936–21944. 2013.
View Article : Google Scholar : PubMed/NCBI
|
46
|
Bundscherer A, Malsy M, Lange R, Hofmann
P, Metterlein T, Graf BM and Gruber M: Cell harvesting method
influences results of apoptosis analysis by Annexin V staining.
Anticancer Res. 33:3201–3204. 2013.PubMed/NCBI
|
47
|
Zedan W, Mourad MI, El-Aziz SMA, Salamaa
NM and Shalaby AA: Cytogenetic significance of chromosome 17
aberrations and P53 gene mutations as prognostic markers in oral
squamous cell carcinoma. Diagn Pathol. 10:22015. View Article : Google Scholar : PubMed/NCBI
|
48
|
Jin C, Jin Y, Wennerberg J, Akervall J,
Dictor M and Mertens F: Karyotypic heterogeneity and clonal
evolution in squamous cell carcinomas of the head and neck. Cancer
Genet Cytogenet. 132:85–96. 2002. View Article : Google Scholar : PubMed/NCBI
|
49
|
Papavasileiou D, Tosios K, Christopoulos
P, Goutas N and Vlachodimitropoulos D: Her-2 immunohistochemical
expression in oral squamous cell carcinomas is associated with
polysomy of chromosome 17, not Her-2 amplification. Head Neck
Pathol. 3:263–270. 2009. View Article : Google Scholar : PubMed/NCBI
|
50
|
Wang L, Liu T, Nishioka M, Aguirre RL, Win
SS and Okada N: Activation of ERK1/2 and cyclin D1 expression in
oral tongue squamous cell carcinomas: Relationship between
clinicopathological appearances and cell proliferation. Oral Oncol.
42:625–631. 2006. View Article : Google Scholar : PubMed/NCBI
|
51
|
Chambard JC, Lefloch R, Pouysségur J and
Lenormand P: ERK implication in cell cycle regulation. Biochim
Biophys Acta. 1773:1299–1310. 2007. View Article : Google Scholar : PubMed/NCBI
|
52
|
Aguzzi A, Maggioni D, Nicolini G, Tredici
G, Gaini RM and Garavello W: MAP kinase modulation in squamous cell
carcinoma of the oral cavity. Anticancer Res. 29:303–308.
2009.PubMed/NCBI
|
53
|
Kim EK and Choi EJ: Pathological roles of
MAPK signaling pathways in human diseases. Biochim Biophys Acta.
1802:396–405. 2010. View Article : Google Scholar : PubMed/NCBI
|
54
|
Engelbrecht AM, Gebhardt S and Louw L: Ex
vivo study of MAPK profiles correlated with parameters of apoptosis
during cervical carcinogenesis. Cancer Lett. 235:93–99. 2006.
View Article : Google Scholar : PubMed/NCBI
|
55
|
Squatrito M, Brennan CW, Helmy K, Huse JT,
Petrini JH and Holland EC: Loss of ATM/Chk2/p53 pathway components
accelerates tumor development and contributes to radiation
resistance in gliomas. Cancer Cell. 18:619–629. 2010. View Article : Google Scholar : PubMed/NCBI
|
56
|
Hasima N and Aggarwal BB: Cancer-linked
targets modulated by curcumin. Int J Biochem Mol Biol. 3:328–351.
2012.PubMed/NCBI
|
57
|
Baharuddin P, Satar N, Fakiruddin KS,
Zakaria N, Lim MN, Yusoff NM, Zakaria Z and Yahaya BH: Curcumin
improves the efficacy of cisplatin by targeting cancer stem-like
cells through p21 and cyclin D1-mediated tumour cell inhibition in
non-small cell lung cancer cell lines. Oncol Rep. 35:13–25. 2016.
View Article : Google Scholar : PubMed/NCBI
|
58
|
Borges GÁ, Rêgo DF, Assad DX, Coletta RD,
De Luca Canto G and Guerra EN: In vivo and in vitro effects of
curcumin on head and neck carcinoma: A systematic review. J Oral
Pathol Med. 46:3–20. 2017. View Article : Google Scholar : PubMed/NCBI
|