Open Access

Color‑coded duplex sonography vs. 3.0 Tesla magnetic resonance angiography for detection of intracranial stenosis of the internal carotid artery: A prospective cohort study

  • Authors:
    • Lu Xiao
    • Wen Chu
    • Hua Wang
  • View Affiliations

  • Published online on: November 29, 2019     https://doi.org/10.3892/etm.2019.8255
  • Pages: 473-480
  • Copyright: © Xiao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Hemodynamic changes may provide important information for clinical decision‑making in internal carotid artery (ICA) stenosis. The degree of stenosis is responsible for the hemodynamic changes. For detection of intracranial stenosis, each diagnostic method has its own advantages and disadvantages. The goal of the present study was to compare the sensitivity and accuracy of color‑coded duplex sonography with that of magnetic resonance angiography (MRA) for the detection of intracranial stenosis. Patients with 3 vessels and/or left stem coronary artery disease were subjected to transcranial and extracranial color‑coded duplex sonography (n=998), MRA (n=998) and invasive catheter angiography (n=939). The degree of stenosis was defined according to the Warfarin‑Aspirin Symptomatic Intracranial Disease methodology. A ≥50% reduction in artery diameter was considered as a positive obstructive lesion. The benefits of each imaging method were assessed by clinical decision‑making analysis. Color‑coded duplex sonography and MRA, had sensitivities of 0.935 and 0.957 and accuracies of 0.92 and 0.974, respectively, when using invasive catheter angiography as a gold standard. The number of false‑positive obstructive lesions detected by MRA was significantly higher than that for color‑coded duplex sonography (53 vs. 13, P<0.0001). Color‑coded duplex sonography was able to detect an obstructive lesion in one single image for ICAs with ≥57% stenosis, while MRA was only capable of detecting an obstructive lesion in one single image for ICAs with ≥80% stenosis. In conclusion, color‑coded duplex sonography is a reliable method for the detection of intracranial stenosis in patients with coronary artery disease.
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January-2020
Volume 19 Issue 1

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Spandidos Publications style
Xiao L, Chu W and Wang H: Color‑coded duplex sonography vs. 3.0 Tesla magnetic resonance angiography for detection of intracranial stenosis of the internal carotid artery: A prospective cohort study. Exp Ther Med 19: 473-480, 2020.
APA
Xiao, L., Chu, W., & Wang, H. (2020). Color‑coded duplex sonography vs. 3.0 Tesla magnetic resonance angiography for detection of intracranial stenosis of the internal carotid artery: A prospective cohort study. Experimental and Therapeutic Medicine, 19, 473-480. https://doi.org/10.3892/etm.2019.8255
MLA
Xiao, L., Chu, W., Wang, H."Color‑coded duplex sonography vs. 3.0 Tesla magnetic resonance angiography for detection of intracranial stenosis of the internal carotid artery: A prospective cohort study". Experimental and Therapeutic Medicine 19.1 (2020): 473-480.
Chicago
Xiao, L., Chu, W., Wang, H."Color‑coded duplex sonography vs. 3.0 Tesla magnetic resonance angiography for detection of intracranial stenosis of the internal carotid artery: A prospective cohort study". Experimental and Therapeutic Medicine 19, no. 1 (2020): 473-480. https://doi.org/10.3892/etm.2019.8255