Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
February-2020 Volume 19 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
February-2020 Volume 19 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Effects of surgery and radiofrequency ablation in the treatment of spinal metastases and analysis of the influencing factors of prognosis

  • Authors:
    • Meiling Li
    • Yan Zhang
    • Xiujuan Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Gynecology, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China, Department of General Surgery, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China
    Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1072-1078
    |
    Published online on: December 10, 2019
       https://doi.org/10.3892/etm.2019.8310
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Effects of surgery and radiofrequency ablation in the treatment of spinal metastases were explored to analyze the influencing factors of prognosis. A total of 132 patients with spinal metastases admitted to Weifang People's Hospital were selected, 67 patients who underwent simple surgery were selected as the control group, and 65 patients who underwent radiofrequency ablation assisted surgery were the research group. The time of operation and intraoperative blood loss of patients in the two groups were recorded and compared. The visual analogue pain score (VAS), Karnofsky (KPS) score, Frankel spinal cord injury grading, and complications within 6 months after surgery were compared. The patients were followed up for 36 months and the survival rates were analyzed. Cox regression model was used to analyze the factors affecting the prognosis of patients. The time of operation and blood loss in the research group was significantly lower than that in the control group (P<0.05). The VAS, KPS scores, and Frankel grading of patients in the two groups after treatment were significantly improved compared with those before treatment, but the VAS and KPS scores of patients in the research group were significantly improved compared with those in the control group (P<0.05). The incidence rate of complications and 3-year recurrence rate in the research group were lower than those in the control group, and the 3-year survival rate was significantly higher than that in the control group (P<0.05). The number of pathological cones, visceral metastasis, malignant degree, and radiofrequency ablation therapy are independent risk factors for poor prognosis of patients. Radiofrequency ablation assisted surgery can effectively improve the clinical efficacy of patients with spinal metastases, reduce postoperative complications and recurrence rate of patients, and prolong the survival time of patients compared with simple surgical treatment. It is worthy of clinical application.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Wang J, Fang Z, Lang N, Yuan H, Su MY and Baldi P: A multi-resolution approach for spinal metastasis detection using deep Siamese neural networks. Comput Biol Med. 84:137–146. 2017. View Article : Google Scholar : PubMed/NCBI

2 

Roser S, Maharaj MM, Taylor MA, Kuru R, Hansen MA and Ferch R: Vertebrectomy in metastatic spinal tumours: A 10 year, single-centre review of outcomes and survival. J Clin Neurosci. 68:218–223. 2019. View Article : Google Scholar : PubMed/NCBI

3 

Gharzai LA, Beeler WH, Hayman JA, Mancini B, Jagsi R, Pierce L, Moran JM, Dominello MM, Boike T, Griffith K, et al Michigan Radiation Oncology Quality Consortium, : Recommendations for single faction radiation therapy and stereotactic body radiation therapy in palliative treatment of bone metastases: A statewide practice patterns survey. Pract Radiat Oncol. 9:e541–e548. 2019. View Article : Google Scholar : PubMed/NCBI

4 

Pennington Z, Ahmed AK, Cottrill E, Westbroek EM, Goodwin ML and Sciubba DM: Intra- and interobserver reliability of the Spinal Instability Neoplastic Score system for instability in spine metastases: A systematic review and meta-analysis. Ann Transl Med. 7:2182019. View Article : Google Scholar : PubMed/NCBI

5 

Schaub SK, Tseng YD, Chang EL, Sahgal A, Saigal R, Hofstetter CP, Foote M, Ko AL, Yuh WTC, Mossa-Basha M, et al: Strategies to mitigate toxicities from stereotactic body radiation therapy for spine metastases. Neurosurgery. 85:729–740. 2019. View Article : Google Scholar : PubMed/NCBI

6 

Zhang Y, Zhang MB, Luo YK, Li J, Zhang Y and Tang J: Effect of chronic lymphocytic thyroiditis on the efficacy and safety of ultrasound-guided radiofrequency ablation for papillary thyroid microcarcinoma. Cancer Med. 8:5450–5458. 2019. View Article : Google Scholar : PubMed/NCBI

7 

Leto G: Current status and future directions in the treatment of bone metastases from breast cancer. Clin Exp Pharmacol Physiol. 46:968–971. 2019. View Article : Google Scholar : PubMed/NCBI

8 

van Amerongen MJ, van der Stok EP, Fütterer JJ, Jenniskens SFM, Moelker A, Verhoef C, Grünhagen DJ and de Wilt JHW: Results after simultaneous surgery and RFA liver ablation for patients with colorectal carcinoma and synchronous liver metastases. Eur J Surg Oncol. Jul 7–2019.(Epub ahead of print). View Article : Google Scholar : PubMed/NCBI

9 

Wallace AN, Tomasian A, Vaswani D, Vyhmeister R, Chang RO and Jennings JW: Radiographic local control of spinal metastases with percutaneous radiofrequency ablation and vertebral augmentation. AJNR Am J Neuroradiol. 37:759–765. 2016. View Article : Google Scholar : PubMed/NCBI

10 

Cooke ME, Welch T, Gusakov O and Tornetta P III: Are continuous femoral nerve catheters beneficial for pain management after operative fixation of tibial plateau fractures? A randomized controlled trial. J Orthop Trauma. 33:e447–e451. 2019. View Article : Google Scholar : PubMed/NCBI

11 

Barbetta C, Allgar V, Maddocks M, Ribeiro C, Wilcock A, Currow DC, Phillips J and Johnson MJ: Australia-modified Karnofsky Performance Scale and physical activity in COPD and lung cancer: An exploratory pooled data analysis. BMJ Support Palliat Care. Jul 11–2019.(Epub ahead of print). View Article : Google Scholar : PubMed/NCBI

12 

Capaul M, Zollinger H, Satz N, Dietz V, Lehmann D and Schurch B: Analyses of 94 consecutive spinal cord injury patients using ASIA definition and modified Frankel score classification. Paraplegia. 32:583–587. 1994.PubMed/NCBI

13 

Buergy D, Sharfo AW, Heijmen BJ, Voet PW, Breedveld S, Wenz F, Lohr F and Stieler F: Fully automated treatment planning of spinal metastases - A comparison to manual planning of Volumetric Modulated Arc Therapy for conventionally fractionated irradiation. Radiat Oncol. 12:332017. View Article : Google Scholar : PubMed/NCBI

14 

Hamad A, Vachtsevanos L, Cattell A, Ockendon M and Balain B: Minimally invasive spinal surgery for the management of symptomatic spinal metastasis. Br J Neurosurg. 31:526–530. 2017. View Article : Google Scholar : PubMed/NCBI

15 

Guzik G: Oncological and functional results of the surgical treatment of vertebral metastases in patients with multiple myeloma. BMC Surg. 17:922017. View Article : Google Scholar : PubMed/NCBI

16 

Patchell RA, Tibbs PA, Regine WF, Payne R, Saris S, Kryscio RJ, Mohiuddin M and Young B: Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: A randomised trial. Lancet. 366:643–648. 2005. View Article : Google Scholar : PubMed/NCBI

17 

de Ruiter GC, Nogarede CO, Wolfs JF and Arts MP: Quality of life after different surgical procedures for the treatment of spinal metastases: Results of a single-center prospective case series. Neurosurg Focus. 42:E172017. View Article : Google Scholar : PubMed/NCBI

18 

Kam NM, Maingard J, Kok HK, Ranatunga D, Brooks D, Torreggiani WC, Munk PL, Lee MJ, Chandra RV and Asadi H: Combined vertebral augmentation and radiofrequency ablation in the management of spinal metastases: An update. Curr Treat Options Oncol. 18:742017. View Article : Google Scholar : PubMed/NCBI

19 

Griessenauer CJ, Salem M, Hendrix P, Foreman PM, Ogilvy CS and Thomas AJ: Preoperative embolization of spinal tumors: A systematic review and meta-analysis. World Neurosurg. 87:362–371. 2016. View Article : Google Scholar : PubMed/NCBI

20 

Stephenson MB, Glaenzer B and Malamis A: Percutaneous minimally invasive techniques in the treatment of spinal metastases. Curr Treat Options Oncol. 17:562016. View Article : Google Scholar : PubMed/NCBI

21 

Toyota N, Naito A, Kakizawa H, Hieda M, Hirai N, Tachikake T, Kimura T, Fukuda H and Ito K: Radiofrequency ablation therapy combined with cementoplasty for painful bone metastases: Initial experience. Cardiovasc Intervent Radiol. 28:578–583. 2005. View Article : Google Scholar : PubMed/NCBI

22 

Wang GW, Han XX, Ma YL, Duo J, Yang JL and Liao ZC: Radiofrequency ablation combined with subtotal corpectomy for spinal metastases. Chin J Orthop. 31:938–943. 2011.(In Chinese).

23 

Hu H, Yang HL, Wang GL, Chen KW, Zhou QS and Zhou M: The decision-making and survival prediction role of Tomita score in the management spinal metastases. Chin J Spin Spin Cord. 22:673–677. 2012.(In Chinese).

24 

Hibberd CS and Quan GMY: Accuracy of preoperative scoring systems for the prognostication and treatment of patients with spinal metastases. Int Sch Res Notices. 2017:13206842017.PubMed/NCBI

25 

Pointillart V, Vital JM, Salmi R, Diallo A and Quan GM: Survival prognostic factors and clinical outcomes in patients with spinal metastases. J Cancer Res Clin Oncol. 137:849–856. 2011. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Li M, Zhang Y and Zhang X: Effects of surgery and radiofrequency ablation in the treatment of spinal metastases and analysis of the influencing factors of prognosis. Exp Ther Med 19: 1072-1078, 2020.
APA
Li, M., Zhang, Y., & Zhang, X. (2020). Effects of surgery and radiofrequency ablation in the treatment of spinal metastases and analysis of the influencing factors of prognosis. Experimental and Therapeutic Medicine, 19, 1072-1078. https://doi.org/10.3892/etm.2019.8310
MLA
Li, M., Zhang, Y., Zhang, X."Effects of surgery and radiofrequency ablation in the treatment of spinal metastases and analysis of the influencing factors of prognosis". Experimental and Therapeutic Medicine 19.2 (2020): 1072-1078.
Chicago
Li, M., Zhang, Y., Zhang, X."Effects of surgery and radiofrequency ablation in the treatment of spinal metastases and analysis of the influencing factors of prognosis". Experimental and Therapeutic Medicine 19, no. 2 (2020): 1072-1078. https://doi.org/10.3892/etm.2019.8310
Copy and paste a formatted citation
x
Spandidos Publications style
Li M, Zhang Y and Zhang X: Effects of surgery and radiofrequency ablation in the treatment of spinal metastases and analysis of the influencing factors of prognosis. Exp Ther Med 19: 1072-1078, 2020.
APA
Li, M., Zhang, Y., & Zhang, X. (2020). Effects of surgery and radiofrequency ablation in the treatment of spinal metastases and analysis of the influencing factors of prognosis. Experimental and Therapeutic Medicine, 19, 1072-1078. https://doi.org/10.3892/etm.2019.8310
MLA
Li, M., Zhang, Y., Zhang, X."Effects of surgery and radiofrequency ablation in the treatment of spinal metastases and analysis of the influencing factors of prognosis". Experimental and Therapeutic Medicine 19.2 (2020): 1072-1078.
Chicago
Li, M., Zhang, Y., Zhang, X."Effects of surgery and radiofrequency ablation in the treatment of spinal metastases and analysis of the influencing factors of prognosis". Experimental and Therapeutic Medicine 19, no. 2 (2020): 1072-1078. https://doi.org/10.3892/etm.2019.8310
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team