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Article

DSA‑guided percutaneous sclerotherapy for children with oropharyngeal low‑flow venous malformation

  • Authors:
    • Dan Song
    • Lei Guo
    • Hui Sheng
    • Jing Li
    • Liang Wang
    • Changhua Wu
    • Changfeng Wang
    • Yanli Niu
    • Qingshi Zeng
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China, Department of Vascular Anomalies and Interventional Radiology, Jinan, Shandong 250022, P.R. China, Department of Radiology, Qilu Children’s Hospital of Shandong University, Jinan, Shandong 250022, P.R. China
  • Pages: 3405-3410
    |
    Published online on: March 6, 2020
       https://doi.org/10.3892/etm.2020.8581
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Abstract

The present study investigated the efficacy and safety of digital subtraction angiography‑guided 3% polidocanol foam sclerosing agent, as well as the combination of pingyangmycin and dexamethasone, for the treatment of children with oropharyngeal low‑flow venous malformation. A total of 27 children with 35 lesions with oropharyngeal low‑flow venous malformation were included. The subjects were randomly divided into Groups A (13 patients with 16 lesions, treated with 3% polidocanol foam sclerosing agent) and B (14 patients with 19 lesions, treated with pingyangmycin + dexamethasone), respectively. The clinical efficacies and adverse reactions were analyzed and compared between these two groups. The average number of treatment times for Group A was 2.45±0.6, with an efficacy rate of 87.50%, while the average number of treatment times for Group B was 2.07±0.4, with an efficacy rate of 84.21%. No significant difference was found in the average treatment times or efficacy rates between Groups A and B. In addition, the adverse reaction incidence for Groups A and B were 38.46 and 14.29%, respectively, with statistically significant differences between these two groups. The combination of pingyangmycin and dexamethasone was safe and effective in treating children with oropharyngeal low‑flow venous malformation, with fewer adverse reactions and is worthy of clinical promotion.
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1 

Rabe E and Pannier F: Sclerotherapy in venous malformation. Phlebology. 28 (Suppl 1):S188–S191. 2013.PubMed/NCBI View Article : Google Scholar

2 

Bai N, Chen YZ, Fu YJ, Wu P and Zhang WN: A clinical study of pingyangmycin sclerotherapy for venous malformation: An evaluation of 281 consecutive patients. J Clin Pharm Ther. 39:521–526. 2014.PubMed/NCBI View Article : Google Scholar

3 

Lee BB, Baumgartner I, Berlien P, Bianchini G, Burrows P, Gloviczki P, Huang Y, Laredo J, Loose DA, Markovic J, et al: Diagnosis and treatment of venous malformations. Consensus document of the international union of phlebology (IUP): Updated 2013. Int Angiol. 34:97–149. 2015.PubMed/NCBI

4 

Greene AK and Alomari AI: Management of venous malformations. Clin Plast Surg. 38:83–93. 2011.PubMed/NCBI View Article : Google Scholar

5 

Berenguer B, Burrows PE, Zurakowski D and Mulliken JB: Sclerotherapy of craniofacial venous malformations: Complications and results. Plast Reconstr Surg. 104:1–11, Discussion 12-15. 1999.PubMed/NCBI

6 

Van der Vleuten CJ, Kater A, Wijnen MH, Schultze Kool LJ and Rovers MM: Effectiveness of sclerotherapy, surgery, and laser therapy in patients with venous malformations: A systematic review. Cardiovasc Intervent Radiol. 37:977–989. 2014.PubMed/NCBI View Article : Google Scholar

7 

Jing Z, Haibo L and Shaoyi Z: Comparative study of sclerotherapy of venous malformation in children using absolute ethanol and pingyangmycin. Chin J Radiol. 46:350–353. 2012.

8 

Xue-Guo LI, Ren-Rong L, Feng X, et al: Meta analysis of treatment of superficial venous malformation with Bleomycin injection treatment. Chin J Aesth Plast Surg, 2016.

9 

Ribeiro MC, de Mattos Camargo Grossmann S, do Amaral MBF, de Castro WH, Navarro TP, Procopio RJ, da Silva TA, de Nazaré Alvesde, Oliveira Kato C and Mesquita RA: Effectiveness and safety of foam sclerotherapy with 5% ethanolamine oleate in the treatment of low-flow venous malformations in the head and neck region: A case series. Int J Oral Maxillofac Surg. 47:900–907. 2018.PubMed/NCBI View Article : Google Scholar

10 

Kumar S, Bhavana K, Kumar S and Kumar P: Ultrasound-guided polidocanol foam sclerotherapy for treating venous malformations. J Clin Ultrasound. 46:23–31. 2018.PubMed/NCBI View Article : Google Scholar

11 

Department of Vascular Diseases OaMS, Chinese Academy of Stomatology: Guide to the treatment of oral and maxillofacial hemangioma and vascular malformations. Nat Med J China 88: 3102.3107, 2008.

12 

McCafferty I: Management of low-flow vascular malformations: Clinical presentation, classification, patient selection, imaging and treatment. Cardiovasc Intervent Radiol. 38:1082–1104. 2015.PubMed/NCBI View Article : Google Scholar

13 

Tessari L, Cavezzi A and Frullini A: Preliminary experience with a new sclerosing foam in the treatment of varicose veins. Dermatol Surg. 27:58–60. 2001.PubMed/NCBI

14 

Murakami T, Ogata D, Miyano K and Tsuchida T: An enlarged intramuscular venous malformation in the femoral region successfully treated with complete resection. Int J Surg Case Rep. 21:83–86. 2016.PubMed/NCBI View Article : Google Scholar

15 

Lee BB, Laredo J, Kim YW and Neville R: Congenital vascular malformations: General treatment principles. Phlebology. 22:258–263. 2007.PubMed/NCBI View Article : Google Scholar

16 

Puig S, Aref H, Chigot V, Bonin B and Brunelle F: Classification of venous malformations in children and implications for sclerotherapy. Pediatr Radiol. 33:99–103. 2003.PubMed/NCBI View Article : Google Scholar

17 

Zhenyin L, Haibo L, Shaoyi Z, Kaunshan C, Chuanqiang N, Tao Z and Jing Z: Clinical study on sclerotherapy using absolute ethanol combined with polidocanol injectable foam in treatment of venous malformation in maxillofacial region of children. Chin J Intervent. 5:235–240. 2017.

18 

Aboelatta YA, Nagy E, Shaker M and Massoud KS: Venous malformations of the head and neck: A diagnostic approach and a proposed management approach based on clinical, radiological, and histopathology findings. Head Neck. 36:1052–1057. 2014.PubMed/NCBI View Article : Google Scholar

19 

Chen AW, Liu YR, Li K, Zhang K, Wang T and Liu S: Efficacy of sclerotherapy with radio-opaque foam guided by digital subtraction angiography for the treatment of complex venous malformations of the head and neck. Br J Oral Maxillofac Surg. 53:809–813. 2015.PubMed/NCBI View Article : Google Scholar

20 

Ouvry P, Allaert FA, Desnos P and Hamel-Desnos C: Efficacy of polidocanol foam ver-sus 1iquid in sclerotherapy of the great saphenous vein: A multicenter randomized controlled trial with a 2 year follow-up. Eur J Vasc Endovasc Surg. 36:366–370. 2008.PubMed/NCBI View Article : Google Scholar

21 

Blaise S, Charavin-Cocuzza M, Riom H, Brix M, Seinturier C, Diamand JM, Gachet G and Carpentier PH: Treatment of low-flow vascular malformations by ultrasound-guided sclerotherapy with polidocanol foam: 24 cases and literature review. Eur J Vasc Endovasc Surg. 41:412–417. 2011.PubMed/NCBI View Article : Google Scholar

22 

Cabrera J, Cabrera J Jr, Garcia-Olmedo MA and Redondo P: Treatment of venous malformations with sclerosant in microfoam form. Arch Dermatol. 139:1409–1416. 2003.PubMed/NCBI View Article : Google Scholar

23 

Zhai J and Zhai XD: Combined injection of pingyangmycin & dexamethasone for the treatment of maxillofacial and cervical venous malformations. Zhonghua Zheng Xing Wai Ke Za Zhi. 28:168–171. 2012.PubMed/NCBI(In Chinese).

24 

Spence J, Krings T, TerBrugge KG and Agid R: Percutaneous treatment of facial venous: Malformations: A matched comparison of alcohol and Bleomycin sclerotherapy. Head Neck. 33:125–130. 2011.PubMed/NCBI View Article : Google Scholar

25 

Gao Y, Chen H, Jin Y, et al: Retrospective analysis of neuropathy following sclerotherapy for treating venous malformations. J Tissue Eng Reconstruct Surgery, 2016.

26 

Zheng JW, Yang XJ, Wang YA, He Y, Ye WM and Zhang ZY: Intralesional injection of Pingyangmycin for vascular malformations in oral and maxillofacial regions: An evaluation of 297 consecutive patients. Oral Oncol. 45:872–876. 2009.PubMed/NCBI View Article : Google Scholar

27 

Hsu TS and Weiss RA: Foam sclerotherapy: A new era. Arch Dermatol. 139:1494–1496. 2003.PubMed/NCBI View Article : Google Scholar

28 

Wenxian Z, Fangfang L, Yifan Y, Huiling Y and Xue L: Clinical efficacy of combination therapy with ethanol +foam sclerotherapy +bleomycin A5 +medical elastic sleeve for venous malformation in children. Chin J Intervent Radiol (Electronic Edition). 4:227–230. 2017.

29 

Steiner F, FitzJohn T and Tan ST: Ethanol sclerotherapy for venous malformation. ANZ J Surg. 86:790–795. 2016.PubMed/NCBI View Article : Google Scholar

30 

Weitz-Tuoretmaa A, Keski-Nisula L, Rautio R and Laranne J: Quality of life after endovascular sclerotherapy of low-flow venous malformations: The efficacy of polidocanol compared with ethanol. Acta Radiol. 59:946–952. 2018.PubMed/NCBI View Article : Google Scholar

31 

Jingwei WU: Pingyangmycin in combination with dexamethasone injection in the treatment of oral and maxillofacial and neck venous malformations of clinical effect assessment. China Continuing Medical Education, 2016.

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Copy and paste a formatted citation
Spandidos Publications style
Song D, Guo L, Sheng H, Li J, Wang L, Wu C, Wang C, Niu Y and Zeng Q: DSA‑guided percutaneous sclerotherapy for children with oropharyngeal low‑flow venous malformation. Exp Ther Med 19: 3405-3410, 2020.
APA
Song, D., Guo, L., Sheng, H., Li, J., Wang, L., Wu, C. ... Zeng, Q. (2020). DSA‑guided percutaneous sclerotherapy for children with oropharyngeal low‑flow venous malformation. Experimental and Therapeutic Medicine, 19, 3405-3410. https://doi.org/10.3892/etm.2020.8581
MLA
Song, D., Guo, L., Sheng, H., Li, J., Wang, L., Wu, C., Wang, C., Niu, Y., Zeng, Q."DSA‑guided percutaneous sclerotherapy for children with oropharyngeal low‑flow venous malformation". Experimental and Therapeutic Medicine 19.5 (2020): 3405-3410.
Chicago
Song, D., Guo, L., Sheng, H., Li, J., Wang, L., Wu, C., Wang, C., Niu, Y., Zeng, Q."DSA‑guided percutaneous sclerotherapy for children with oropharyngeal low‑flow venous malformation". Experimental and Therapeutic Medicine 19, no. 5 (2020): 3405-3410. https://doi.org/10.3892/etm.2020.8581
Copy and paste a formatted citation
x
Spandidos Publications style
Song D, Guo L, Sheng H, Li J, Wang L, Wu C, Wang C, Niu Y and Zeng Q: DSA‑guided percutaneous sclerotherapy for children with oropharyngeal low‑flow venous malformation. Exp Ther Med 19: 3405-3410, 2020.
APA
Song, D., Guo, L., Sheng, H., Li, J., Wang, L., Wu, C. ... Zeng, Q. (2020). DSA‑guided percutaneous sclerotherapy for children with oropharyngeal low‑flow venous malformation. Experimental and Therapeutic Medicine, 19, 3405-3410. https://doi.org/10.3892/etm.2020.8581
MLA
Song, D., Guo, L., Sheng, H., Li, J., Wang, L., Wu, C., Wang, C., Niu, Y., Zeng, Q."DSA‑guided percutaneous sclerotherapy for children with oropharyngeal low‑flow venous malformation". Experimental and Therapeutic Medicine 19.5 (2020): 3405-3410.
Chicago
Song, D., Guo, L., Sheng, H., Li, J., Wang, L., Wu, C., Wang, C., Niu, Y., Zeng, Q."DSA‑guided percutaneous sclerotherapy for children with oropharyngeal low‑flow venous malformation". Experimental and Therapeutic Medicine 19, no. 5 (2020): 3405-3410. https://doi.org/10.3892/etm.2020.8581
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