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Ultrasound, X‑ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study

  • Authors:
    • Yurong Ge
    • Shuchun Liu
  • View Affiliations / Copyright

    Affiliations: Department of Ultrasonic Medicine, Guiyang Maternal and Child Health Hospital, Guiyang, Guizhou 550003, P.R. China, Department of Anesthesiology, Guizhou Provincial People's Hospital, Guiyang, Guizhou 550002, P.R. China
    Copyright: © Ge et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3559-3564
    |
    Published online on: April 3, 2020
       https://doi.org/10.3892/etm.2020.8643
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Abstract

Imaging modalities are not included in The European League Against Rheumatism, The Pediatric Rheumatology International Trials Organization and The Pediatric Rheumatology European Society 2010 criteria for the evaluation of abdominal purpura. The objective of the present study was to compare diagnostic parameters of ultrasound, X‑ray and computed tomography (CT) for diagnosis of abdominal purpura considering the American College of Rheumatology (ACR) criteria as ‘reference standard’ in children with acute abdominal pain. Medical records of 215 children with acute abdominal pain were reviewed. Data regarding demographics and clinical characteristics, laboratory tests, X‑ray, ultrasound findings, and computed tomographic images were collected and analyzed. Decision curve analysis was used for evaluation of the beneficial score for each diagnostic modality. Among diagnostic modalities, CT had the highest sensitivity (0.939); however, ultrasound findings had the highest accuracy (0.861) for diagnosis of abdominal purpura. Unlike X‑ray and laboratory tests, ultrasound and CT were successful at detecting abdominal purpura when children had only colicky pain and were aged <20 years; however, occult blood stool test and granulocytes in the walls of small venules and arterioles (biopsy results) were negative. With respect to the ACR criteria, there were seven and three inconclusive results for ultrasound and CT, respectively. Abdominal ultrasound is an easy, non‑invasive and safe method for the detection of abdominal purpura in children.
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1 

Başaran Ö, Cakar N, Uncu N, Celikel BA, Kara A, Cayci FS, Taktak A and Gür G: Plasma exchange therapy for severe gastrointestinal involvement of henoch schönlein purpura in children. Clin Exp Rheumatol. 33 (Suppl 89):S176–S180. 2015.PubMed/NCBI

2 

Srivali N, Ungprasert P, Ahmed S, Cheungpasitporn W and Bischof EF: A case of childhood vasculitis presenting in adulthood. Am J Emerg Med. 31:254–255. 2013.PubMed/NCBI View Article : Google Scholar

3 

Lim CJ, Chen JH, Chen WL, Shen YS and Huang CC: Jejunojejunum intussusception as the single initial manifestation of Henoch-Schönlein purpura in a teenager. Am J Emerg Med. 30(2085)2012.PubMed/NCBI View Article : Google Scholar

4 

McPartland K and Wright G: Acute abdominal pain: Henoch-Schönlein purpura case in a young adult, a rare but important diagnosis. Clin Med (Lond). 19:77–79. 2019.PubMed/NCBI View Article : Google Scholar

5 

Zhang Q, Guo Q, Gui M, Ren Z, Hu B, Lu L and Deng F: Henoch-Schönlein purpura with acute pancreatitis: Analysis of 13 cases. BMC Pediatr. 18(159)2018.PubMed/NCBI View Article : Google Scholar

6 

Yang YH, Yu HH and Chiang BL: The diagnosis and classification of Henoch-Schönlein purpura: An updated review. Autoimmun Rev. 13:355–358. 2014.PubMed/NCBI View Article : Google Scholar

7 

Keenswijk W, Van Renterghem K and Vande Walle J: A case report of a child with purpura, severe abdominal pain, and hematochezia. Gastroenterology. 153:e10–e11. 2017.PubMed/NCBI View Article : Google Scholar

8 

Yang Z, Guo L, Xiong H, Gang Z, Li JX, Deng YP, Dawa QZ, Pubu ZX and Li H: Clinical analysis of childhood Henoch-Schonlein purpura on the Tibetan Plateau, China. Zhongguo Dang Dai Er Ke Za Zhi. 16:1231–1235. 2014.PubMed/NCBI(In Chinese).

9 

Batu ED and Ozen S: Vasculitis: Do we know more to classify better? Pediatr Nephrol. 30:1425–1432. 2015.PubMed/NCBI View Article : Google Scholar

10 

Reamy BV, Williams PM and Lindsay TJ: Henoch-Schönlein purpura. Am Fam Physician. 80:697–704. 2009.PubMed/NCBI

11 

BMJ Best Practice. Evaluation of abdominal pain in children. https://bestpractice.bmj.com/topics/en-us/787/diagnosis-approach. Accessed December 1, 2018.

12 

Brody AS, Frush DP, Huda W and Brent RL: American academy of pediatrics section on radiology. Radiation risk to children from computed tomography. Pediatrics. 120:677–682. 2007.PubMed/NCBI View Article : Google Scholar

13 

Chang WL, Yang YH, Lin YT and Chiang BL: Gastrointestinal manifestations in Henoch-Schönlein purpura: A review of 261 patients. Acta Paediatr. 93:1427–1431. 2004.PubMed/NCBI View Article : Google Scholar

14 

Teng X, Gao C, Sun M and Wu J: Clinical significance of fecal calprotectin for the early diagnosis of abdominal type of Henoch-Schonlein purpura in children. Clin Rheumatol. 37:1667–1673. 2018.PubMed/NCBI View Article : Google Scholar

15 

Ozen S, Pistorio A, Iusan SM, Bakkaloglu A, Herlin T, Brik R, Buoncompagni A, Lazar C, Bilge I, Uziel Y, et al: Paediatric rheumatology international trials organisation (PRINTO). EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood wegener granulomatosis and childhood takayasu arteritis: Ankara 2008. Part II: Final classification criteria. Ann Rheum Dis. 69:798–806. 2010.PubMed/NCBI View Article : Google Scholar

16 

Kirpalani H and Nahmias C: Letter: Radiation risk to children from computed tomography. Pediatrics. 121:449–450. 2008.

17 

Pelin M, Paquette B, Revel L, Landecy M, Bouveresse S and Delabrousse E: Acute appendicitis: Factors associated with inconclusive ultrasound study and the need for additional computed tomography. Diagn Interv Imaging. 99:809–814. 2018.PubMed/NCBI View Article : Google Scholar

18 

Chen O, Zhu XB, Ren P, Wang YB, Sun RP and Wei DE: Henoch schonlein purpura in children: Clinical analysis of 120 cases. Afr Health Sci. 13:94–99. 2013.PubMed/NCBI View Article : Google Scholar

19 

Liu LJ, Yu J and Li YN: Clinical characteristics of Henoch-Schönlein purpura in children. Zhongguo Dang Dai Er Ke Za Zhi. 17:1079–1083. 2015.PubMed/NCBI(In Chinese).

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Copy and paste a formatted citation
Spandidos Publications style
Ge Y and Liu S: Ultrasound, X‑ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study . Exp Ther Med 19: 3559-3564, 2020.
APA
Ge, Y., & Liu, S. (2020). Ultrasound, X‑ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study . Experimental and Therapeutic Medicine, 19, 3559-3564. https://doi.org/10.3892/etm.2020.8643
MLA
Ge, Y., Liu, S."Ultrasound, X‑ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study ". Experimental and Therapeutic Medicine 19.6 (2020): 3559-3564.
Chicago
Ge, Y., Liu, S."Ultrasound, X‑ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study ". Experimental and Therapeutic Medicine 19, no. 6 (2020): 3559-3564. https://doi.org/10.3892/etm.2020.8643
Copy and paste a formatted citation
x
Spandidos Publications style
Ge Y and Liu S: Ultrasound, X‑ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study . Exp Ther Med 19: 3559-3564, 2020.
APA
Ge, Y., & Liu, S. (2020). Ultrasound, X‑ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study . Experimental and Therapeutic Medicine, 19, 3559-3564. https://doi.org/10.3892/etm.2020.8643
MLA
Ge, Y., Liu, S."Ultrasound, X‑ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study ". Experimental and Therapeutic Medicine 19.6 (2020): 3559-3564.
Chicago
Ge, Y., Liu, S."Ultrasound, X‑ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study ". Experimental and Therapeutic Medicine 19, no. 6 (2020): 3559-3564. https://doi.org/10.3892/etm.2020.8643
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