|
1
|
Kearney PM, Whelton M, Reynolds K, Muntner
P, Whelton PK and He J: Global burden of hypertension: Analysis of
worldwide data. Lancet. 365:217–223. 2005.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Writing Group Members. Mozaffarian D,
Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, de
Ferranti S, Després JP, et al: Heart Disease and Stroke
Statistics-2016 Update: A Report From the American Heart
Association. Circulation. 133:e338–e360. 2016.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Svetkey LP, Harris EL, Eden M, Vollmer WM,
Meltesen GT, Ricchiuti V, Williams G, Appel LJ, Bray GA, Moore TJ,
et al: Modulation of the BP response to diet by genes in the
renin-angiotensin system and the adrenergic nervous system. Am J
Hypertens. 24:209–217. 2011.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Cai X: Regulation of smooth muscle cells
in development and vascular disease: Current therapeutic
strategies. Expert Rev Cardiovasc Ther. 4:789–800. 2006.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Haudenschild CC, Grunwald J and Chobanian
AV: Effects of hypertension on migration and proliferation of
smooth muscle in culture. Hypertension. 7:I101–1104.
1985.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Belo VA, Guimarães DA and Castro MM:
Matrix metalloproteinase 2 as a potential mediator of vascular
smooth muscle cell migration and chronic vascular remodeling in
hypertension. J Vasc Res. 52:221–231. 2016.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Bavishi C, Bangalore S and Messerli FH:
Renin angiotensin aldosterone system inhibitors in hypertension: Is
there evidence for benefit independent of blood pressure reduction?
Prog Cardiovasc Dis. 59:253–261. 2016.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Churchill PC: Second messengers in renin
secretion. Am J Physiol. 249:175–184. 1985.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Genest J, Nowaczynski W, Boucher R, Kuchel
O and Rojo-Ortega JM: Aldosterone and renin in essential
hypertension. Can Med Assoc J. 113:421–431. 1975.PubMed/NCBI
|
|
10
|
Touyz RM: The role of angiotensin II in
regulating vascular structural and functional changes in
hypertension. Curr Hypertens Rep. 5:155–164. 2003.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Allender PS, Cutler JA, Follmann D,
Cappuccio FP, Pryer J and Elliott P: Dietary calcium and blood
pressure: A meta-analysis of randomized clinical trials. Ann Intern
Med. 124:825–831. 1996.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Atchison DK, Ortiz-Capisano MC and
Beierwaltes WH: Acute activation of the calcium-sensing receptor
inhibits plasma renin activity in vivo. Am J Physiol Regul Integr
Comp Physiol. 299:R1020–R1026. 2010.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Ayachi S: Increased dietary calcium lowers
blood pressure in the spontaneously hypertensive rat. Metabolism.
28:1234–1238. 1979.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Wang R, Xu C, Zhao W, Zhang J, Cao K, Yang
B and Wu L: Calcium and polyamine regulated calcium-sensing
receptors in cardiac tissues. Eur J Biochem. 270:2680–2688.
2003.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Yamamura A, Yamamura H, Guo Q, Zimnicka
AM, Wan J, Ko EA, Smith KA, Pohl NM, Song S, Zeifman A, et al:
Dihydropyridine Ca(2+) channel blockers increase cytosolic [Ca(2+)]
by activating Ca(2+)-sensing receptors in pulmonary arterial smooth
muscle cells. Circ Res. 112:640–650. 2013.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Guo J, Li HZ, Zhang WH, Wang LC, Wang LN,
Zhang L, Li GW, Li HX, Yang BF, Wu L, et al: Increased expression
of calcium-sensing receptors induced by ox-LDL amplifies apoptosis
of cardiomyocytes during simulated ischaemia-reperfusion. Clin Exp
Pharmacol Physiol. 37:e128–e135. 2010.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Weston AH, Geraghty A, Egner I and Edwards
G: The vascular extracellular calcium-sensing receptor: An update.
Acta Physiol (Oxf). 203:127–137. 2011.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Rybczynska A, Jurska-Jasko A, Boblewski K,
Lehmann A and Orlewska C: Blockade of calcium channels and AT1
receptor prevents the hypertensive effect of calcilytic NPS 2143 in
rats. J Physiol Pharmacol. 61:163–170. 2010.PubMed/NCBI
|
|
19
|
Rybczynska A, Lehmann A, Jurska-Jasko A,
Boblewski K, Orlewska C, Foks H and Drewnowska K: Hypertensive
effect of calcilytic NPS 2143 administration in rats. J Endocrinol.
191:189–195. 2006.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Ogata H, Ritz E, Odoni G, Amann K and Orth
SR: Beneficial effects of calcimimetics on progression of renal
failure and cardiovascular risk factors. J Am Soc Nephrol.
14:959–967. 2003.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Ortiz-Capisano MC, Reddy M, Mendez M,
Garvin JL and Beierwaltes WH: Juxtaglomerular cell CaSR stimulation
decreases renin release via activation of the PLC/IP(3) pathway and
the ryanodine receptor. Am J Physiol Renal Physiol. 304:F248–F256.
2013.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Qu YY, Hui J, Wang LM, Tang N, Zhong H,
Liu YM, Li Z, Feng Q and He F: Reduced expression of the
extracellular calcium-sensing receptor (CaSR) is associated with
activation of the renin-angiotensin system (RAS) to promote
vascular remodeling in the pathogenesis of essential hypertension.
PLoS One. 11(e0157456)2016.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Sun R, Zhang W, Zhong H, Wang L, Tang N,
Liu Y, Zhao Y, Zhang T and He F: Calcimimetic R568 reduced the
blood pressure and improved aortic remodeling in spontaneously
hypertensive rats by inhibiting local renin-angiotensin system
activity. Exp Ther Med. 16:4089–4099. 2018.PubMed/NCBI View Article : Google Scholar
|
|
24
|
U.S. National Institutes of Health.
Laboratory animal welfare: Public Health Service policy on humane
care and use of laboratory animals by awardee institutions; notice.
Fed Regist. 50:19584–19585. 1985.PubMed/NCBI
|
|
25
|
Chi J, Meng L, Pan S, Lin H, Zhai X, Liu
L, Zhou C, Jiang C and Guo H: Primary culture of rat aortic
vascular smooth muscle cells: A New Method. Med Sci Monit.
23:4014–4020. 2017.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Valero MS, Pereboom D, Barcelo-Batllory S,
Brines L, Garay RP and Alda JO: Protein kinase A signalling is
involved in the relaxant responses to the selective β-oestrogen
receptor agonist diarylpropionitrile in rat aortic smooth muscle in
vitro. J Pharm Pharmacol. 63:222–229. 2011.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Yamaguchi T, Ida T, Hiraga M, Oishi K,
Uchida MK and Echizen H: Effects of angiotensin II receptor
blockers, angiotensin converting enzyme inhibitors,
3-hydroxy-3-methyl glutaryl (HMG) CoA reductase inhibitors,
amlodipine and epalrestat on cultured basilar artery smooth muscle
cell proliferation. Yakugaku Zasshi. 124:159–163. 2004.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Kim JE and Choi HC: Losartan inhibits
vascular smooth muscle cell proliferation through activation of
AMP-activated protein kinase. Korean J Physiol Pharmacol.
14:299–304. 2010.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Yamamura A, Ohara N and Tsukamoto K:
Inhibition of excessive cell proliferation by calcilytics in
idiopathic pulmonary arterial hypertension. PLoS One.
10(e0138384)2015.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Method. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Kobayashi-Torii M, Takahashi Y, Sunanaga
J, Fujita M, Lee EY, Ichimaru Y, Fujita T, Kanmura Y and Kuwaki T:
Possible participation of extracellular calcium-sensing receptor in
blood presure regulation in rats. Brain Res. 1367:181–187.
2011.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Smajilovic S, Hansen JL, Christoffersen
TE, Lewin E, Sheikh SP, Terwilliger EF, Brown EM, Haunso S and
Tfelt-Hansen J: Extracellular calcium sensing in rat aortic
vascular smooth muscle cells. Biochem Biophys Res Commun.
348:1215–1223. 2006.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Maillard MP, Tedjani A, Perregaux C and
Burnier M: Calcium-sensing receptors modulate renin release in vivo
and in vitro in the rat. J Hypertens. 27:1980–1997. 2009.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Ström A, Franzén A, Wängnerud C, Knutsson
AK, Heinegård D and Hultgårdh-Nilsson A: Altered vascular
remodeling in osteopontin-deficient atherosclerotic mice. J Vasc
Res. 41:314–322. 2004.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Lai YM, Fukuda N, Su JZ, Suzuki R, Ikeda
Y, Takagi H, Tahira Y and Kanmatsuse K: Novel mechanisms of the
antiproliferative effects of amlodipine in vascular smooth muscle
cells from spontaneously hypertensive rats. Hypertens Res.
25:109–115. 2002.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Yi B, Cui J, Ning JN, Wang GS, Qian GS and
Lu KZ: Over-expression of PKGIα inhibits hypoxia-induced
proliferation, Akt activation, and phenotype modulation of human
PASMCs: The role of phenotype modulation of PASMCs in pulmonary
vascular remodeling. Gene. 492:354–360. 2012.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Dickhout JG and Lee RM: Apoptosis in the
muscular arteries from young spontaneously hypertensive rats. J
Hypertens. 17:1413–1419. 1999.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Song L, Gao LN, Wang J, Thapa S, Li Y,
Zhong XB, Zhao HW, Xiang XR, Zhang FG and Ji P: Stromal
Cell-derived factor-1αalleviates calcium-sensing receptor
activation-mediated ischemia/reperfusion injury by inhibiting
caspase-3/caspase-9-induced cell apoptosis in rat free flaps.
Biomed Res Int. 2018(8945850)2018.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Mcconkey DJ and Orrenius S: The role of
calcium in the regulation of apoptosis. Biochem Biophys Res Commun.
239:357–366. 1997.PubMed/NCBI View Article : Google Scholar
|
|
40
|
McConkey DJ and Orrenius S: Signal
transduction pathways to apoptosis. Trends Cell Biol. 4:370–375.
1994.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Schiffrin EL and Touyz RM: From bedside to
bench to bedside: Role of renin-angiotensin-aldosterone system in
remodeling of resistance arteries in hypertension. Am J Physiol
Heart Circ Physiol. 287:H435–H446. 2004.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Gomes RA, Teodoro Ld, Lopes IC, Bersanetti
PA, Carmona AK and Hial V: Angiotensin-converting enzyme in
pericardial fluid: Comparative study with serum activity. Arq Bras
Cardiol. 91:156–161. 2008.PubMed/NCBI(In English, Portuguese).
|
|
43
|
Intengan HD and Schiffrin EL: Vascular
remodeling in hypertension: Roles of apoptosis, inflammation, and
fibrosis. Hypertension. 38:581–587. 2001.PubMed/NCBI View Article : Google Scholar
|
|
44
|
deBlois D, Orlov SN and Hamet P: Apoptosis
in cardiovascular remodeling-effect of medication. Cardiovasc Drugs
Ther. 15:539–545. 2001.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Tea BS, Der Sarkissian S, Touyz RM, Hamet
P and deBlois D: Proapoptotic and growth-inhibitory role of
angiotensin II type 2 receptor in vascular smooth muscle cells of
spontaneously hypertensive rats in vivo. Hypertension.
35:1069–1073. 2000.PubMed/NCBI View Article : Google Scholar
|
