Journal Articles

Open Access

Respiratory diseases in the era of Covid‑19: Pearls and pitfalls

Maria Bolaki, Eliza Tsitoura, Demetrios A. Spandidos, Emmanouil K. Symvoulakis, Katerina M. Antoniou

Pages: 691-693 Published online on: 20 May 2020
Open Access

Rivaroxaban treatment for young patients with pulmonary embolism (Review)

Haidi Wu, Hongyan Cao, Zikai Song, Xiaoyan Xu, Minglong Tang, Shuo Yang, Yang Liu, Ling Qin

Pages: 694-704 Published online on: 25 May 2020
Open Access

Radix Puerariae rebalances vasomotor factors and improves left ventricular diastolic dysfunction in patients with essential hypertension

Yan Liu, Su Liang, Peili Bu, Ershun Liang, Fangfang Yan, Yifan Xing, Pengfei Zhang

Pages: 705-713 Published online on: 13 May 2020
Open Access

Mast cell‑mediated neuroinflammation may have a role in attention deficit hyperactivity disorder (Review)

Yuchen Song, Manqi Lu, Haixia Yuan, Tianyi Chen, Xinmin Han

Pages: 714-726 Published online on: 25 May 2020
Open Access

Interpretable artificial intelligence framework for COVID‑19 screening on chest X‑rays

Nikos Tsiknakis, Eleftherios Trivizakis, Evangelia E. Vassalou, Georgios Z. Papadakis, Demetrios A. Spandidos, Aristidis Tsatsakis, Jose Sánchez‑García, Rafael López‑González, Nikolaos Papanikolaou, Apostolos H. Karantanas, Kostas Marias

Pages: 727-735 Published online on: 27 May 2020
Open Access

STIM1 controls calcineurin/Akt/mTOR/NFATC2‑mediated osteoclastogenesis induced by RANKL/M‑CSF

Yanjiao Huang, Qiang Li, Zunyong Feng, Lanrong Zheng

Pages: 736-747 Published online on: 19 May 2020
Open Access

Characterization of novel intramedullary nailing method for treating femoral shaft fracture through finite element analysis

Yunwei Cui, Wenzhao Xing, Zhenhua Pan, Zhigang Kong, Liang Sun, Lei Sun, Xiaodong Cheng, Changcheng Liu

Pages: 748-753 Published online on: 18 May 2020
Open Access

Serum levels of 14‑3‑3η are associated with increased disease risk, activity and duration of rheumatoid arthritis in Chinese patients

Jianxin Tu, Xiaowei Chen, Meijie Dai, Axiao Pan, Cailong Liu, Yan Zhou, Xiaoru Xia, Li Sun

Pages: 754-761 Published online on: 17 May 2020
Open Access

Evaluation of the TRPM protein family as potential biomarkers for various types of human cancer using public database analyses

Fuchuang Qin, Lingdi Lao, Minhua Huang, Hang Tan, Xuhong Jin, Xilie Ma, Jianping Zeng

Pages: 770-785 Published online on: 12 May 2020
Open Access

Three‑year clinical observation of the outcomes of transepithelial and epithelial‑off accelerated corneal collagen crosslinking treatment for different types of progressive keratoconus

Jin‑Rong Huang, Hong‑Fei Liao, Chun‑Hong Wan, Li‑Miao Gong, Liang‑Fei He, Hong‑Ji Jiang, Biao Li, Yi Shao

Pages: 786-795 Published online on: 12 May 2020
Open Access

Protective effect of hypothermia and vitamin E on spermatogenic function after reduction of testicular torsion in rats

Xuejun Bo, Ping Wang, Yan Nie, Rongfen Li, Jiru Lu, Haiying Wang

Pages: 796-801 Published online on: 27 May 2020
Open Access

TRIM31 enhances chemoresistance in glioblastoma through activation of the PI3K/Akt signaling pathway

Ming‑De Fan, Xue‑Ying Zhao, Jian‑Ni Qi, Yang Jiang, Bing‑Yu Liu, Zhi‑Ping Dun, Rui Zhang, Cheng‑Wei Wang, Qi Pang

Pages: 802-809 Published online on: 21 May 2020
Open Access

Analysis of indications for pulmonary peripheral lesions diagnosed using radial endobronchial ultrasound‑guided transbronchial lung biopsy

Shu‑Hong Guan, Ming Zhang, Su‑Juan Zhang, Qiu‑Di Zhang, Qian‑Qian Xu, Jun Zhou

Pages: 810-817 Published online on: 12 May 2020
Open Access

Calcilytic NPS2143 promotes proliferation and inhibits apoptosis of spontaneously hypertensive rat vascular smooth muscle cells via activation of the renin‑angiotensin system

Yongli Zhao, Na Tang, Dongmei Xi, Zhen Huang, Tian Zhang, Yongmin Liu, Lamei Wang, Yan Tang, Hua Zhong, Fang He

Pages: 818-829 Published online on: 15 May 2020
Open Access

Role of pulmonary function and FeNO detection in early screening of patients with ACO

Jing Wang, Wenting Wang, Huan Lin, Cheng Huan, Shujuan Jiang, Dianjie Lin, Naiqing Cao, Hongsheng Ren

Pages: 830-837 Published online on: 17 May 2020
Open Access

Metformin attenuates cardiac remodeling in mice through the Nrf2/Keap1 signaling pathway

Jingxia Du, Mengxi Zhu, Hongchao Li, Gaofeng Liang, Yan Li, Shuying Feng

Pages: 838-845 Published online on: 18 May 2020
Open Access

H2Mab‑19, an anti‑human epidermal growth factor receptor 2 monoclonal antibody exerts antitumor activity in mouse oral cancer xenografts

Junko Takei, Mika Kato Kaneko, Tomokazu Ohishi, Manabu Kawada, Hiroyuki Harada, Yukinari Kato

Pages: 846-853 Published online on: 18 May 2020
Open Access

Ameliorating effect of quercetin on epilepsy by inhibition of inflammation in glial cells

Dongmei Wu, Zihui Zheng, Shaohua Fan, Xin Wen, Xinrui Han, Shan Wang, Yongjian Wang, Zifeng Zhang, Qun Shan, Mengqiu Li, Bin Hu, Yuanlin Zheng, Jun Lu

Pages: 854-859 Published online on: 13 May 2020
Open Access

Evaluation of the role of Nrf2/Keap1 pathway‑associated novel mutations and gene expression on antioxidant status in patients with deep vein thrombosis

Di̇lara Fatma Akin‑Bali, Tamer Eroglu, Sedef Ilk, Yonca Egi̇n, Teoman Kankilic

Pages: 868-881 Published online on: 25 May 2020
Open Access

Investigation of the health effects on workers exposed to respirable crystalline silica during outdoor and underground construction projects

Dimitrios Keramydas, Petros Bakakos, Manos Alchanatis, Petros Papalexis, Ioannis Konstantakopoulos, Kyriaki Tavernaraki, Vasileios Dracopoulos, Antonios Papadakis, Eugenia Pantazi, Georgios Chelidonis, Elias Chaidoutis, Theodoros C. Constantinidis, Christina Tsitsimpikou, Nikolaos Kavantzas, Efstratios Patsouris, Konstantinos Tsarouhas, Demetrios A. Spandidos, Andreas Ch. Lazaris

Pages: 882-889 Published online on: 25 May 2020
Open Access

Paxillin promotes the migration and angiogenesis of HUVECs and affects angiogenesis in the mouse cornea

Wan‑Ju Yang, Jiang‑Bo Yan, Li Zhang, Fang Zhao, Zhong‑Ming Mei, Yan‑Ning Yang, Yi Xiang, Yi‑Qiao Xing

Pages: 901-909 Published online on: 14 May 2020
Open Access

Serum COX‑2 and FOXO3a in patients with rheumatoid arthritis and correlation with disease activity

Bangqin Wang, Xinxiang Huang, Jinying Lin

Pages: 910-916 Published online on: 21 May 2020
Open Access

Dexmedetomidine‑mediated regulation of miR‑17‑3p in H9C2 cells after hypoxia/reoxygenation injury

Tianhui Yuan, Zhongqi Yang, Shaoxiang Xian, Yang Chen, Lingjun Wang, Weitao Chen, Wenjie Long, Yuanyuan Che

Pages: 917-925 Published online on: 20 May 2020
Open Access

Knockdown of Mg2+/Mn2+ dependent protein phosphatase 1A promotes apoptosis in BV2 cells infected with Brucella suis strain 2 vaccine

Juan Yang, Guowei Wang, Haining Li, Wenli Zheng, Burui Guo, Zhenhai Wang

Pages: 926-932 Published online on: 13 May 2020
Open Access

Radiographic study of Sever's disease

Yan Gao, Jia Liu, Yifang Li, Qing Liu, Shuhua Xu

Pages: 933-937 Published online on: 26 May 2020
Open Access

miR‑187‑3p increases gemcitabine sensitivity in breast cancer cells by targeting FGF9 expression

Yingqi Wu, Li Tao, Junwei Liang, Yashun Qiao, Weiwei Liu, Haina Yu, Xinghui Yu, Lanfang Liu

Pages: 952-960 Published online on: 19 May 2020
Open Access

Updates on the molecular genetics of primary congenital glaucoma (Review)

Chen Ling, Dingding Zhang, Jing Zhang, Huanxin Sun, Qiu Du, Xuefei Li

Pages: 968-977 Published online on: 18 May 2020
Open Access

lncRNA MCM3AP‑AS1 promotes the development of oral squamous cell carcinoma by inhibiting miR‑363‑5p

Chao Hou, Xu Wang, Bo Du

Pages: 978-984 Published online on: 12 May 2020
Open Access

Comparison of serum fibrosis biomarkers for diagnosing significant liver fibrosis in patients with chronic hepatitis B

Yuki Tsuji, Tadashi Namisaki, Kosuke Kaji, Hiroaki Takaya, Keisuke Nakanishi, Shinya Sato, Soichiro Saikawa, Yasuhiko Sawada, Kou Kitagawa, Naotaka Shimozato, Hideto Kawaratani, Kei Moriya, Ryuichi Noguchi, Takemi Akahane, Akira Mitoro, Hitoshi Yoshiji

Pages: 985-995 Published online on: 27 May 2020
Open Access

Systemic lupus erythematosus with hypothyroidism as the initial clinical manifestation: A case report

Xuejiao Zhang, Baofeng Xu, Ziwei Liu, Yuanyuan Gao, Qing Wang, Rui Liu

Pages: 996-1002 Published online on: 25 May 2020
Open Access

Interleukin‑22 is elevated in the atrium and plasma of patients with atrial fibrillation and increases collagen synthesis in transforming growth factor‑β1‑treated cardiac fibroblasts via the JNK pathway

Yongxin Wu, Lihua Tan, Lei Shi, Zicong Yang, Yan Xue, Tao Zeng, Ying Shi, Yingzhong Lin, Ling Liu

Pages: 1012-1020 Published online on: 21 May 2020
Open Access

Interaction between ICAM1 in endothelial cells and LFA1 in T cells during the pathogenesis of experimental Parkinson's disease

Wenjie Li, Sheng Chen, Yuan Luo, Yezi Xia, Qianqian Ma, Qi Yao, Jianqing Wu

Pages: 1021-1029 Published online on: 15 May 2020
Open Access

CCR3‑shRNA promotes apoptosis and inhibits chemotaxis and degranulation of mouse mast cells

Haisen Peng, Bing Liao, Xinhua Zhu, Yuehui Liu, Yinli Jiang, Shuhong Wu

Pages: 1030-1038 Published online on: 12 May 2020
Open Access

Retrospective analysis of 19 papulopustular rosacea cases treated with oral minocycline and supramolecular salicylic acid 30% chemical peels

Lian Wang, Xiao‑Hua Li, Xiang Wen, Xiao‑Xue Li, Dan Du, Yong Li, Xian Jiang

Pages: 1048-1052 Published online on: 12 May 2020
Open Access

Ulinastatin attenuates lipopolysaccharide‑induced cardiac dysfunction by inhibiting inflammation and regulating autophagy

Pin Zhao, Li Zhang, Longfei Gao, Qian Ding, Qian Yang, Jianke Kuai

Pages: 1064-1072 Published online on: 15 May 2020
Open Access

Efficient detection of differentially methylated regions in the genome of patients with thoracic aortic dissection and association with MMP2 hypermethylation

Ni Li, Hangjuan Lin, Hua Zhou, Dawei Zheng, Guodong Xu, Huoshun Shi, Xiuying Zhu, Jianqing Gao, Guofeng Shao, Lebo Sun

Pages: 1073-1081 Published online on: 15 May 2020
Open Access

Cognitive improvements and reduction in amyloid plaque deposition by saikosaponin D treatment in a murine model of Alzheimer's disease

Li Zhou, Jin‑Yuan Huang, Di Zhang, Ya‑Liang Zhao

Pages: 1082-1090 Published online on: 17 May 2020
Open Access

Prognosis of distal pancreatic cancers controlled by stage

Guopei Luo, Kaizhou Jin, He Cheng, Meng Guo, Yitao Gong, Zhiyao Fan, Chao Yang, Qiuyi Huang, Quanxing Ni, Chen Liu, Xianjun Yu

Pages: 1091-1097 Published online on: 26 May 2020
Open Access

Cardiac injury after acute carbon monoxide poisoning and its clinical treatment scheme

Shoumeng Geng, Xiaoyan Hao, Haicang Xu, Jian Yao, Dongyong He, Hui Xin, Xingji Gong, Rui Zhang

Pages: 1098-1104 Published online on: 27 May 2020

Neutrophil‑to‑lymphocyte ratio and red blood cell distribution width‑to‑platelet ratio predict cardiovascular events in hemodialysis patients

Xiangjun Zhu, Gongqi Li, Shujuan Li, Zhuang Gong, Jun Liu, Shu Song

Pages: 1105-1114 Published online on: 15 May 2020

Application of capsular bag relaxation for capsular contraction syndrome

De‑Jian Xu, Hai‑Jian Wu, Ling‑Jie Zhang

Pages: 1115-1120 Published online on: 19 May 2020

miR‑181a‑5p regulates the proliferation and apoptosis of glomerular mesangial cells by targeting KLF6

Xinyue Liang, Wen Xu

Pages: 1121-1128 Published online on: 21 May 2020

Comparison of FlowGate2 and Merci as balloon guide catheters used in mechanical thrombectomies for stroke intervention

Ho Jun Yi, Dong Hoon Lee, Jae Hoon Sung

Pages: 1129-1136 Published online on: 15 May 2020

Macleaya cordata extracts exert antiviral effects in newborn mice with rotavirus‑induced diarrhea via inhibiting the JAK2/STAT3 signaling pathway

Chunmao Jiang, Haifeng Yang, Xiaolan Chen, Shulei Qiu, Caihong Wu, Bin Zhang, Liqin Jin

Pages: 1137-1144 Published online on: 18 May 2020

Synedrella nodiflora (Linn.) Gaertn. inhibits inflammatory responses through the regulation of Syk in RAW 264.7 macrophages

Hien Thi Thu Le, Jiyoung Park, Jain Ha, Susi Kusumaningrum, Jin Hyub Paik, Sayeon Cho

Pages: 1153-1162 Published online on: 13 May 2020

Ultrasound‑guided transversus abdominis plane block using ropivacaine and dexmedetomidine in patients undergoing caesarian sections to relieve post‑operative analgesia: A randomized controlled clinical trial

Haitao Qian, Qingwei Zhang, Pin Zhu, Xiaobao Zhang, Liang Tian, Jiying Feng, Yong Wu, Zhibin Zhao, Hengfei Luan

Pages: 1163-1168 Published online on: 21 May 2020

Identification of a lncRNA‑miRNA‑mRNA network based on competitive endogenous RNA theory reveals functional lncRNAs in hypertrophic cardiomyopathy

Lichan Tao, Jia Shi, Xiaoli Huang, Fei Hua, Ling Yang

Pages: 1176-1190 Published online on: 13 May 2020
Open Access

Effects of regulating miR-132 mediated GSK-3β on learning and memory function in mice

Gang Liu, Fengwei Yin, Congli Zhang, Yang Zhang, Xiaohong Li, Yunzhi Ling

Pages: 1191-1197 Published online on: 19 May 2020
Open Access

C‑reactive protein and cardiovascular disease: From animal studies to the clinic (Review)

Yu Fu, Yi Wu, Enqi Liu

Pages: 1211-1219 Published online on: 04 June 2020

Pathophysiology of hepatic Na+/H+ exchange (Review)

Tingting Li, Biguang Tuo

Pages: 1220-1229 Published online on: 12 June 2020
Open Access

Acute coronary syndrome with ST segment elevation in a patient with Addison disease: Case report and brief review of physiopathological mechanisms: A case study

Minela Aida Maranduca, Cristian Statescu, Radu Andy Sascau, Nicoleta Dima, Loredana Liliana Hurjui, Dragomir Nicolae Serban, Ionela Lacramioara Serban

Pages: 1230-1236 Published online on: 10 June 2020
Open Access

Clinical diagnosis, treatment and screening of the VHL gene in three von Hippel‑Lindau disease pedigrees

Guobing Lin, Yihua Zhao, Zhewei Zhang, Huijiang Zhang

Pages: 1237-1244 Published online on: 03 June 2020
Open Access

Ginsenoside Rg1 protects against Sca‑1+ HSC/HPC cell aging by regulating the SIRT1‑FOXO3 and SIRT3‑SOD2 signaling pathways in a γ‑ray irradiation‑induced aging mice model

Yan‑Long Tang, Yue Zhou, Ya‑Ping Wang, Ying‑Hong He, Ji‑Chao Ding, Yuan Li, Cui‑Li Wang

Pages: 1245-1252 Published online on: 28 May 2020
Open Access

Trp53 regulates platelets in bone marrow via the PI3K pathway

Mingming Yang, Qing Liu, Ting Niu, Jianbiao Kuang, Xiaohan Zhang, Lingbi Jiang, Siqi Li, Xiaodong He, Lijing Wang, Jiangchao Li

Pages: 1253-1260 Published online on: 09 June 2020
Open Access

SIRT3 is a downstream target of PPAR-α implicated in high glucose-induced cardiomyocyte injury in AC16 cells

Xiaojuan Zong, Kuan Cheng, Guizhi Yin, Zhaodi Wu, Qian Su, Dong Yu, Pengfei Liao, Wei Hu, Yueguang Chen

Pages: 1261-1268 Published online on: 10 June 2020
Open Access

TLR‑4, TLR‑5 and IRF4 are diagnostic markers of knee osteoarthritis in the middle-aged and elderly patients and related to disease activity and inflammatory factors

Wenchao Han, Xiumin Chen, Xianyin Wang, Zhen Shen, Xiaobing Wang, Zuofeng Zhang, Huiru Wang

Pages: 1291-1298 Published online on: 30 May 2020
Open Access

Effects of diabetes on the rebleeding rate following endoscopic treatment in patients with liver cirrhosis

Xi Wang, Xuecan Mei, Derun Kong

Pages: 1299-1306 Published online on: 11 June 2020
Open Access

In vitro induction and in vivo engraftment of kidney organoids derived from human pluripotent stem cells

Denglu Zhang, Xiaohang Du, Xufeng Zhang, Kailin Li, Feng Kong, Guanghui Cheng, Shengtian Zhao

Pages: 1307-1314 Published online on: 05 June 2020
Open Access

Low‑dose dobutamine stress myocardial contrast echocardiography for the evaluation of myocardial microcirculation and prediction of overall cardiac function recovery

Yunjia Lin, Xin Guan, Kai Ren, Yanbo Zhu, Yaping Lu, Yanwen Shang

Pages: 1315-1320 Published online on: 28 May 2020
Open Access

Effect of valproic acid on oxidative stress parameters of glutamate‑induced excitotoxicity in SH‑SY5Y cells

Berna Terzi̇oğlu Bebi̇toğlu, Eli̇f Oğuz, Gökçe Acet

Pages: 1321-1328 Published online on: 27 May 2020
Open Access

Apigenin induces apoptosis and counteracts cisplatin‑induced chemoresistance via Mcl‑1 in ovarian cancer cells

Yuyan Qi, Zhaoxia Ding, Yushuang Yao, Feifei Ren, Min  Yin, Songbin Yang, Aiping Chen

Pages: 1329-1336 Published online on: 11 June 2020
Open Access

Application of blood pre-albumin and NT-pro BNP levels in evaluating prognosis of elderly chronic heart failure patients

Linying Shi, Yuan Zhang, Jing Zhang, Yuanfeng Gao, Jiamei Liu, Mulei Chen, Xinchun Yang

Pages: 1337-1342 Published online on: 10 June 2020
Open Access

miR-331 inhibits CLDN2 expression and may alleviate the vascular endothelial injury induced by sepsis

Lingchen Kong, Peng Wu, Jianzhong Li

Pages: 1343-1352 Published online on: 10 June 2020
Open Access

Value of Dyna CT in guiding embolization during transarterial uterine artery embolization of fibroids

Cao‑Ye Wang, Jin‑Guo Xia, Wen‑Hua Chen, Yi‑Feng Lu, Zong‑Hong Han, Qi Wang

Pages: 1353-1358 Published online on: 11 June 2020
Open Access

Integrative transcriptomics and metabolomics analyses provide hepatotoxicity mechanisms of asarum

Sa Cao, Lintao Han, Yamin Li, Shiqi Yao, Shuaihong Hou, Shi‑Shi Ma, Wangqiang  Dai, Jingjing Li, Zhenxiang Zhou, Qiong Wang, Fang Huang

Pages: 1359-1370 Published online on: 28 May 2020
Open Access

ZMIZ1 promotes the proliferation and migration of melanocytes in vitiligo

Meng Li, Yibin Fan, Yutong Wang, Jinhua Xu, Hui Xu

Pages: 1371-1378 Published online on: 05 June 2020
Open Access

miR-30 inhibits proliferation of trophoblasts in preeclampsia rats partially related to MAPK/ERK pathway

Yufeng Wang, Luo Jie, Haifeng Gong, Yuqin Li, Anxia Xie, Yanjun Li, Hong Guo

Pages: 1379-1384 Published online on: 10 June 2020
Open Access

Treatment with Pluchea indica (L.) Less. leaf ethanol extract alleviates liver injury in multiple low‑dose streptozotocin‑induced diabetic BALB/c mice

Jongdee Nopparat, Aekkaraj Nualla‑Ong, Amornrat Phongdara

Pages: 1385-1396 Published online on: 11 June 2020
Open Access

CacyBP/SIP promotes tumor progression by regulating apoptosis and arresting the cell cycle in osteosarcoma

Ming Zhao, Run‑Zi Zhang, Dian‑Wen Qi, Hong‑Yi Chen, Guo‑Chuan Zhang

Pages: 1397-1404 Published online on: 05 June 2020
Open Access

Collagen triple helix repeat containing 1 promotes endometrial cancer cell migration by activating the focal adhesion kinase signaling pathway

Xiang Hu, Yiding Bian, Xiaoli Wen, Mengfei Wang, Yiran Li, Xiaoping Wan

Pages: 1405-1414 Published online on: 04 June 2020
Open Access

TP53 mutation influences the efficacy of treatment of colorectal cancer cell lines with a combination of sirtuin inhibitors and chemotherapeutic agents

Hao Yang, Ya Chen, Yuan Jiang, Dongliang Wang, Jun Yan, Zhaoli Zhou

Pages: 1415-1422 Published online on: 29 May 2020
Open Access

Population pharmacokinetics model and initial dose optimization of tacrolimus in children and adolescents with lupus nephritis based on real‑world data

Xiao Chen, Dong‑Dong Wang, Hong Xu, Zhi‑Ping Li

Pages: 1423-1430 Published online on: 30 May 2020
Open Access

Oblongifolin C reverses GEM resistance via suppressing autophagy flux in bladder cancer cells

Zhilong Huang, Tingting Wang, Wenjun Xia, Qing Li, Xinlei Chen, Xiaoli Liu, Peng Wei, Wenping Xu, Meirong Lv

Pages: 1431-1440 Published online on: 10 June 2020
Open Access

Use of the modified Glasgow Coma Scale score to guide sequential invasive‑noninvasive mechanical ventilation weaning in patients with AECOPD and respiratory failure

Jin‑Bo Zhang, Jin‑Qiang Zhu, Lie‑Xiang Cao, Xiao‑Hong Jin, Li‑Li Chen, Yu‑Kang Song, Shi‑Fang Zhou, Ji‑Hong Ma, Hui Fu, Jin‑Zhong Xu, Mei‑Ping Dong, Lai‑Chao Yan, Xian‑Dan Wu, Hui‑Ping Wang, Jun‑Yang Zhou, Yan‑Qiu Wang

Pages: 1441-1446 Published online on: 12 June 2020
Open Access

Identification of a novel mutation in CRYM in a Chinese family with hearing loss using whole‑exome sequencing

Min Wang, Qian Li, Anchun Deng, Xianbai Zhu, Junjie Yang

Pages: 1447-1454 Published online on: 12 June 2020
Open Access

Carboxyamidotriazole exerts anti‑inflammatory activity in lipopolysaccharide‑induced RAW264.7 macrophages by inhibiting NF‑κB and MAPKs pathways

Shan Lu, Mengyuan Duan, Zehao Guo, Yongting Zhou, Danwei Wu, Xiaojuan Zhang, Yicheng Wang, Caiying Ye, Rui Ju, Juan Li, Dechang Zhang, Lei Zhu

Pages: 1455-1466 Published online on: 12 June 2020
Open Access

MicroRNA‑654‑3p enhances cisplatin sensitivity by targeting QPRT and inhibiting the PI3K/AKT signaling pathway in ovarian cancer cells

Yi‑Chao Niu, Jing Tong, Xiao‑Fei Shi, Ting Zhang

Pages: 1467-1479 Published online on: 11 June 2020
Open Access

Effects of fast‑track anesthesia on miR‑1 and neuropeptides in serum of patients undergoing cardiac surgery

Hongxia Zhang, Yongjian Chai, Qinggang Li, Qingtao Han, Zhenqian Lv

Pages: 1480-1486 Published online on: 30 May 2020
Open Access

Correlation between fecal calprotectin, ulcerative colitis endoscopic index of severity and clinical outcome in patients with acute severe colitis

Rong Ma, Rui Meng, Xiang Zhang, Zhijuan Sun, Yuanyuan Lei

Pages: 1498-1504 Published online on: 10 June 2020
Open Access

Gene expression profile analysis on different stages of hypertrophic scarring in a rabbit ear model

Ji Zhu, Mengyan Sun, Yuchong Wang, Hongda Bi, Chunyu Xue

Pages: 1505-1513 Published online on: 11 June 2020
Open Access

miR‑223‑3p reduces high glucose and high fat‑induced endothelial cell injury in diabetic mice by regulating NLRP3 expression

Bo Deng, Ying Hu, Xia Sheng, Huijun Zeng, Yanan Huo

Pages: 1514-1520 Published online on: 10 June 2020
Open Access

Construction of a 14‑lncRNA risk score system predicting survival of children with acute myelocytic leukemia

Shuli Guo, Bo Li, Xiaoyan Xu, Wanli Wang, Songyun Wang, Tao Lv, Huirui Wang

Pages: 1521-1531 Published online on: 05 June 2020
Open Access

Mechanism of TGF‑β1 inhibiting Kupffer cell immune responses in cholestatic cirrhosis

Jun Qian, Yuwen Jiao, Guangyao Wang, Hanyang Liu, Xiang Cao, Haojun Yang

Pages: 1541-1549 Published online on: 30 May 2020
Open Access

miR‑205 regulates bone turnover in elderly female patients with type 2 diabetes mellitus through targeted inhibition of Runx2

Guangfeng Zhang, Huafeng Li, Wenjie Zhao, Min Li, Linlin Tian, Wenwen Ju, Xiaobing Li

Pages: 1557-1565 Published online on: 10 June 2020
Open Access

Clinical efficacy of MVD combined with PSR in the treatment of primary trigeminal neuralgia

Guangyu Zhao, Xiaojun Sun, Zhen Zhang, Hongan Yang, Xiangrong Zheng, Bin Feng

Pages: 1582-1588 Published online on: 10 June 2020
Open Access

Added value of circulating miRNA expression profiling to sonographic TI‑RADS classification in the diagnosis of thyroid nodules

Yu Mao, Fengjiao Zhang, Li He, Fang Luo, Lei Li, Yajie Huo, Zhiqiang Kang

Pages: 1589-1595 Published online on: 10 June 2020
Open Access

Comparison of oral and nasal immunization with inactivated porcine epidemic diarrhea virus on intestinal immunity in piglets

En Zhang, Jialu Wang, Yuchen Li, Lulu Huang, Yongheng Wang, Qian Yang

Pages: 1596-1606 Published online on: 03 June 2020
Open Access

Effects of Eurya japonica extracts on human corneal epithelial cells and experimental dry eye

Lan Li, Rujun Jin, Ying Li, Jong Hyun Nho, Won Choi, Yong Sok Ji, Hyeon Jeong Yoon, Kyung Chul Yoon

Pages: 1607-1615 Published online on: 03 June 2020
Open Access

Application of rib surface positioning ruler combined with volumetric CT measurement technique in endoscopic minimally invasive thoracic wall fixation surgery

Honggang Xia, Zhongyi Sun, Juping Wang, Aixian Tian, Jing Li, Xuan Li, Shan Zhu, Jun Miao, Dongbin Wang

Pages: 1616-1620 Published online on: 10 June 2020
Open Access

Epigallocatechin‑3‑gallate ameliorates LPS‑induced inflammation by inhibiting the phosphorylation of Akt and ERK signaling molecules in rat H9c2 cells

Zhi Hui Li, Zhanli Shi, Shengjie Tang, Hang Ping Yao, Xihua Lin, Fang Wu

Pages: 1621-1629 Published online on: 03 June 2020
Open Access

Elevated estrogen receptor β expression in triple negative breast cancer cells is associated with sensitivity to doxorubicin by inhibiting the PI3K/AKT/mTOR signaling pathway

Shanshan Lei, Peizhi Fan, Mengchuan Wang, Chaojie Zhang, Yu Jiang, Shulin Huang, Meng Fang, Zili He, Aiguo Wu

Pages: 1630-1636 Published online on: 28 May 2020
Open Access

miR‑365b regulates the development of non‑small cell lung cancer via GALNT4

Lei Xing, Xiaodong Hong, Liang Chang, Ping Ren, Hong Zhang

Pages: 1637-1643 Published online on: 10 June 2020
Open Access

Atenolol vs. propranolol for the treatment of infantile haemangiomas: A systematic review and meta‑analysis

Zhuang Liu, Changhua Wu, Dan Song, Liang Wang, Jing Li, Changfeng Wang, Lei Guo

Pages: 1644-1652 Published online on: 05 June 2020
Open Access

miR‑17‑5p and miR‑19b‑3p prevent osteoarthritis progression by targeting EZH2

Yong Li, Fangchang Yuan, Yuxi Song, Xiliang Guan

Pages: 1653-1663 Published online on: 12 June 2020
Open Access

miR‑140‑3p enhances cisplatin sensitivity and attenuates stem cell‑like properties through repressing Wnt/β‑catenin signaling in lung adenocarcinoma cells

Shuoming Wu, Haoran Wang, Yinpeng Pan, Xiangbao Yang, Duoguang Wu

Pages: 1664-1674 Published online on: 05 June 2020
Open Access

Role of Smad3 inhibitor and the pyroptosis pathway in spinal cord injury

Jiajun Zhu, Yu Fu, Guanjun Tu

Pages: 1675-1681 Published online on: 03 June 2020
Open Access

Lipoxin A4 attenuates uric acid‑activated, NADPH oxidase‑dependent oxidative stress by interfering with translocation of p47phox in human umbilical vein endothelial cells

You Zhou, Hui You, Aijie Zhang, Xingliang Jiang, Zheyan Pu, Guoqiang Xu, Mingcai Zhao

Pages: 1682-1692 Published online on: 28 May 2020
Open Access

LncRNA MIR4435‑2HG inhibits the progression of osteoarthritis through miR‑510‑3p sponging

Yingli Liu, Yun Yang, Liangjia Ding, Yuqin Jia, Yuntao Ji

Pages: 1693-1701 Published online on: 05 June 2020
Open Access

Comparative evaluation of 15‑minute rapid diagnosis of ischemic heart disease by high‑sensitivity quantification of cardiac biomarkers

Shengnan He, Long Qu, Xi He, Dan Zhang, Ni Xie

Pages: 1702-1708 Published online on: 10 June 2020

Predictive effect of five hepatitis B virus markers on re-vaccination time of hepatitis B vaccine

Qiuhua Jia, Fei Yu, Qi Zhou, Xiaoyan Chen, Zhaoqi Gu, Chunling Ma

Pages: 1709-1715 Published online on: 10 June 2020
Open Access

A single genetic locus associated with pediatric fractures: A genome-wide association study on 3,230 patients

Roope Parviainen, Sini Skarp, Linda Korhonen, Willy Serlo, Minna Männikkö, Juha-Jaakko Sinikumpu

Pages: 1716-1724 Published online on: 12 June 2020
Open Access

Overexpression of MUC16 predicts favourable prognosis in MUC16-mutant cervical cancer related to immune response

Hao Wang, Chao Yan, Hong Ye

Pages: 1725-1733 Published online on: 04 June 2020

Tumor suppressor REIC/Dkk‑3 and its interacting protein SGTA inhibit glucocorticoid receptor to nuclear transport

Takehiro Iwata, Takuya Sadahira, Kazuhiko Ochiai, Hideo Ueki, Takanori Sasaki, Peng Haung, Motoo Araki, Toyohiko Watanabe, Yasutomo Nasu, Masami Watanabe

Pages: 1739-1745 Published online on: 29 May 2020

MicroRNA‑1307‑3p accelerates the progression of colorectal cancer via regulation of TUSC5

Na Yue, Ming Ye, Ran Zhang, Miao Wang

Pages: 1746-1751 Published online on: 28 May 2020

Stab incision mitomycin C‑assisted rapid trabeculectomy: A ‘SMART’ trabeculectomy alternative

Chryssa Terzidou, Alexandra Trivli, Georgios Dalianis

Pages: 1752-1757 Published online on: 10 June 2020

Anti-tumor peptide SA12 inhibits metastasis of MDA-MB-231 and MCF-7 breast cancer cells via increasing expression of the tumor metastasis suppressor genes, CDH1, nm23-H1 and BRMS1

Longfei Yang, Fang Lin, Zhaowei Gao, Xi Chen, Huizhong Zhang, Ke Dong

Pages: 1758-1763 Published online on: 12 June 2020

Clinical, neuroelectrophysiological and muscular pathological analysis of chronic progressive external ophthalmoplegia

Haidong Lv, Qianqian Qu, Haiyan Liu, Qi Qian, Xianzhao Zheng, Yan Zhang

Pages: 1770-1774 Published online on: 30 May 2020

Vitamin D3 protects articular cartilage by inhibiting the Wnt/β‑catenin signaling pathway

Tao Yang, Wei Sun, Yuan‑Hui Duan, Yun‑Bo Sun, Yi‑Ming Ren, Wei‑Yu Hou, Meng‑Qiang Tian

Pages: 1775-1781 Published online on: 04 June 2020

Changes in the levels of IL‑1β, cortisol and chromogranin A in saliva of subjects with occupational fatigue

Min Ding, Chaoxian Zhao, Yan Li, Xiaoxia Liu, Xueling Wang, Fengli Liu, Jian Wang, Nanyan Xiong, Yonghong Song, Yanli Xu

Pages: 1782-1788 Published online on: 27 May 2020

Effects of rivastigmine hydrogen tartrate and donepezil hydrochloride on the cognitive function and mental behavior of patients with Alzheimer's disease

Xiaohong Zhang, Ronghua Yu, Huilin Wang, Ruifeng Zheng

Pages: 1789-1795 Published online on: 10 June 2020

Quantification evaluation of structural autograft versus morcellized fragments autograft in patients who underwent single‑level lumbar laminectomy

Xiaobin Yang, Dezhi Wang, Yuan He, Liang Yan, Dingjun Hao, Baorong He

Pages: 1803-1807 Published online on: 03 June 2020

Association of MUC2, MUC5AC and MUC5B genes with the recurrence of nasal polyps

Lei Liu, Chaohui Yan, Shudong Tao

Pages: 1808-1814 Published online on: 04 June 2020

Intense pulsed light for the treatment of Meibomian gland dysfunction: A systematic review and meta‑analysis

Shuang Liu, Shaohua Tang, Hong Dong, Xiaohan Huang

Pages: 1815-1821 Published online on: 04 June 2020

Clinical value of color Doppler ultrasound combined with serum CA153, CEA and TSGF detection in the diagnosis of breast cancer

Xiuqin Song, Bo Liang, Chenghong Wang, Shan Shi

Pages: 1822-1828 Published online on: 10 June 2020
Journal Cover

August-2020
Volume 20 Issue 2

Print ISSN: 1792-0981
Online ISSN: 1792-1015

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