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Role of pulmonary function and FeNO detection in early screening of patients with ACO

  • Authors:
    • Jing Wang
    • Wenting Wang
    • Huan Lin
    • Cheng Huan
    • Shujuan Jiang
    • Dianjie Lin
    • Naiqing Cao
    • Hongsheng Ren
  • View Affiliations / Copyright

    Affiliations: Department of Respiration, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China, Department of Intensive Care Unit, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China, Department of Respiration, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China, Department of Allergy, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 830-837
    |
    Published online on: May 17, 2020
       https://doi.org/10.3892/etm.2020.8762
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Abstract

Measurement of fractional exhaled nitric oxide (FeNO) is a quantitative and non-invasive approach to examine airway inflammation, which is a powerful aid in diagnosing chronic disorders of airways like asthma. Diagnostic value of FeNO and relevant indices on pulmonary function in the patients with asthma and chronic obstructive pulmonary disease (COPD) was evaluated. A total of 164 patients [58 asthma, 49 COPD and 57 asthma‑COPD overlap (ACO)] were randomly recruited. FeNO, pulmonary ventilation function, and bronchial diastolic function were performed. Eight indicators including FeNO, vital capacity percentage (VC%), forced vital capacity percentage (FVC%), forced expiratory volume in one second percentage (FEV1%), forced expiratory volume in one second to forced vital capacity percentage (FEV1/FVC%), maximum independent ventilation volume percentage (MVV%), the increased percentage of FEV1 after bronchial diastolic test, the increased absolute value of FEV1 after bronchial diastolic test were examined. Significant difference in VC%, FVC%, FEV1%, FEV1/FVC%, MVV%, the increased absolute value of FEV1 after bronchial diastolic test and FeNO were significantly different between patients with asthma and patients with COPD (P<0.05). There were significant differences of VC%, FVC%, FEV1%, FEV1/FVC%, MVV% and the increased percentage of FEV1 after bronchial diastolic test in cases of patients with asthma compared to ACO patients (P<0.05). There was no statistical significance on VC%, FVC%, FEV1%, FEV1/FVC%, MVV% between COPD patients and ACO patients (P>0.05). However, more importantly, the increased percentage of FEV1 after bronchial diastolic test, the increased absolute value of FEV1 after bronchial diastolic test and the alterations on FeNO were found significantly different in ACO group compared with COPD alone (P<0.05). We compared the results from pulmonary ventilation function, bronchial diastolic function examination as well as FeNO detection among 3 groups of asthma, COPD and ACO. The examination of pulmonary ventilation function and bronchial diastolic function combined with FeNO detection is helpful in the early screening of ACO.
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1 

Postma DS and Boezen HM: Rationale for the Dutch hypothesis. Allergy and airway hyperresponsiveness as genetic factors and their interaction with environment in the development of asthma and COPD. Chest. 126 (Suppl)(S96-S104): discussion S159-S161. 2004.PubMed/NCBI View Article : Google Scholar

2 

Bleecker ER: Similarities and differences in asthma and COPD. The Dutch hypothesis. Chest. 126 (Suppl)(S93-S95): discussion S159-S161. 2004.PubMed/NCBI View Article : Google Scholar

3 

Hunninghake GM, Cho MH, Tesfaigzi Y, Soto-Quiros ME, Avila L, Lasky-Su J, Stidley C, Melén E, Söderhäll C, Hallberg J, et al: MMP12, lung function, and COPD in high-risk populations. N Engl J Med. 361:2599–2608. 2009.PubMed/NCBI View Article : Google Scholar

4 

Shaya FT, Dongyi D, Akazawa MO, Blanchette CM, Wang J, Mapel DW, Dalal A and Scharf SM: Burden of concomitant asthma and COPD in a Medicaid population. Chest. 134:14–19. 2008.PubMed/NCBI View Article : Google Scholar

5 

Aaron SD: Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (Updated 2014). BMJ. 349:1–11. 2014.PubMed/NCBI View Article : Google Scholar

6 

Deng DD, Zhou AY, Shuang QC and Chen P: The value of fractionated exhaled nitric oxide in the diagnosis of asthma-chronic obstructive pulmonary disease overlap syndrome. Zhonghua Jie He He Hu Xi Za Zhi. 40:98–101. 2017.(In Chinese). PubMed/NCBI View Article : Google Scholar

7 

Feng XK, Lin JT, Su N, Liu GL, Chen P, Zhou X, Wan HY, Yin KS and Ma LJ: Investigation and analysis of risk factors of bronchial asthma among people over 14 years old in China. Chin Med J (Engl). 94:1209–1214. 2014.

8 

de Marco R, Pesce G, Marcon A, Accordini S, Antonicelli L, Bugiani M, Casali L, Ferrari M, Nicolini G, Panico MG, et al: The coexistence of asthma and chronic obstructive pulmonary disease (COPD): Prevalence and risk factors in young, middle-aged and elderly people from the general population. PLoS One. 8(e62985)2013.PubMed/NCBI View Article : Google Scholar

9 

Hardin M, Cho M, McDonald ML, Beaty T, Ramsdell J, Bhatt S, van Beek EJ, Make BJ, Crapo JD, Silverman EK, et al: The clinical and genetic features of COPD-asthma overlap syndrome. Eur Respir J. 44:341–350. 2014.PubMed/NCBI View Article : Google Scholar

10 

Menezes AMB, Montes de Oca M, Pérez-Padilla R, Nadeau G, Wehrmeister FC, Lopez-Varela MV, Muiño A, Jardim JRB, Valdivia G and Tálamo C: PLATINO Team. Increased risk of exacerbation and hospitalization in subjects with an overlap phenotype: COPD-asthma. Chest. 145:297–304. 2014.PubMed/NCBI View Article : Google Scholar

11 

Milanese M, Di Marco F, Corsico AG, Rolla G, Sposato B, Chieco-Bianchi F, Costantino MT, Crivellaro MA, Guarnieri G and Scichilone N: ELSA Study Group. Asthma control in elderly asthmatics. An Italian observational study. Respir Med. 108:1091–1099. 2014.PubMed/NCBI View Article : Google Scholar

12 

Alshabanat A, Zafari Z, Albanyan O, Dairi M and FitzGerald JM: Asthma and COPD overlap syndrome (ACOS): A systematic review and meta analysis. PLoS One. 10(e0136065)2015.PubMed/NCBI View Article : Google Scholar

13 

Bonten TN, Kasteleyn MJ, de Mutsert R, Hiemstra PS, Rosendaal FR, Chavannes NH, Slats AM and Taube C: Defining asthma-COPD overlap syndrome: A population-based study. Eur Respir J. 49(1602008)2017.PubMed/NCBI View Article : Google Scholar

14 

Slats A and Taube C: Asthma and chronic obstructive pulmonary disease overlap: Asthmatic chronic obstructive pulmonary disease or chronic obstructive asthma? Ther Adv Respir Dis. 10:57–71. 2016.PubMed/NCBI View Article : Google Scholar

15 

Cosio BG, Soriano JB, López-Campos JL, Calle-Rubio M, Soler-Cataluna JJ, de-Torres JP, Marín JM, Martínez-Gonzalez C, de Lucas P, Mir I, et al: CHAIN Study. Defining the asthma - COPD overlap syndrome in a COPD cohort. Chest. 149:45–52. 2016.PubMed/NCBI View Article : Google Scholar

16 

Boulet LP, FitzGerald JM and Reddel HK: The revised 2014 GINA strategy report: opportunities for change. Curr Opin Pulm Med. 21:1–7. 2015.PubMed/NCBI View Article : Google Scholar

17 

Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, et al: Global strategy for the diagnosis, management and prevention of chronic obstructive lung disease 2017 report: GOLD executive summary. Respirology. 22:575–601. 2017.PubMed/NCBI View Article : Google Scholar

18 

Soler-Cataluña JJ, Cosío B, Izquierdo JL, López-Campos JL, Marín JM, Agüero R, Baloira A, Carrizo S, Esteban C, Galdiz JB, et al: Consensus document on the overlap phenocype COPD-Asthma in COPD. Arch Bronconeumol. 48:331–337. 2012.(In English, Spanish). PubMed/NCBI View Article : Google Scholar

19 

Miller MR, Crapo R, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Enright P, van der Grinten CP, Gustafsson P, et al: ATS/ERS Task Force. General considerations for lung function testing. Eur Respir J. 26:153–161. 2005.PubMed/NCBI View Article : Google Scholar

20 

Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, et al: ATS/ERS Task Force. Standardisation of spirometry. Eur Respir J. 26:319–338. 2005.PubMed/NCBI View Article : Google Scholar

21 

Jiang M, Chen WQ and Zheng JP: Research progress on normal pulmonary ventilation function. Sinochem J Tuberc Respir. 36:973–976. 2013.(In Chinese).

22 

Pulmonary Function Professional Group, Society of Respiratory Diseases, Chinese Medical Association. Pulmonary Function Examination (Part 2)-Spirometry Examination.Chin J Tuberc Respir Dis. 37:481–486. 2014.(In Chinese).

23 

Pulmonary Function Professional Group, Society of Respiratory Diseases, Chinese Medical Association. Pulmonary function examination (part IV) - bronchial diastolic test. Chin J Tuberc Respir Dis. 37:655–658. 2014.(In Chinese).

24 

Deng TT, Zhou AY, Shuang QC and Cheng P: Value of exhaled nitric oxide in the diagnosis of bronchial asthma - chronic obstructive pulmonary disease overlap syndrome. Chin J Tuberc Respir Dis. 40:98–101. 2017.(In Chinese). PubMed/NCBI View Article : Google Scholar

25 

Postma DS and Rabe KF: The asthma - COPD overlap syndrome. N Engl J Med. 373:1241–1249. 2015.PubMed/NCBI

26 

Mendy A, Salo PM, Cohn RD, Wilkerson J, Zeldin DC and Thorne PS: House dust endotoxin association with chronic bronchitis and emphysema. Environ Health Perspect. 126(037007)2018.PubMed/NCBI View Article : Google Scholar

27 

Montes de Oca M and Pérez-Padilla R: Global initiative for chronic obstructive lung disease (GOLD)-2017: The alat perspective. Arch Bronconeumol. 53:87–88. 2017.PubMed/NCBI View Article : Google Scholar

28 

Barrecheguren M, Esquinas C and Miravitlles M: The asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS): Opportunities and challenges. Curr Opin Pulm Med. 21:74–79. 2015.(In English, Spanish). PubMed/NCBI View Article : Google Scholar

29 

Sin DD, Miravitlles M, Mannino DM, Soriano JB, Price D, Celli BR, Leung JM, Nakano Y, Park HY, Wark PA, et al: What is asthma-COPD overlap syndrome? Towards a consensus definition from a round table discussion. Eur Respir J. 48:664–673. 2016.PubMed/NCBI View Article : Google Scholar

30 

Li C, Fang Y and Li ZK: Asthma - COPD overlap syndrome related diseases analysis of 166 cases. Chin J Lung Dis. 6:704–708. 2015.(In Chinese).

31 

Kitaguchi Y, Yasuo M and Hanaoka M: Comparison of pulmonary function in patients with COPD, asthma - COPD overlap syndrome, and asthma with airflow limitation. Int J COPD. 11:99l–997. 2016.(In Chinese). PubMed/NCBI View Article : Google Scholar

32 

Gibson PG and Simpson JL: The overlap syndrome of asthma and COPD: What are its features and how important is it? Thorax. 64:728–735. 2009.PubMed/NCBI View Article : Google Scholar

33 

Zhu L and Shen QJ: Routine pulmonary function parameters and clinical significance in adults. Chin J Tuberc Respir. 35:75–77. 2012.(In Chinese).

34 

Koblizek V, Chlumsky J, Zindr V, Neumannova K, Zatloukal J, Zak J, Sedlak V, Kocianova J, Zatloukal J, Hejduk K, et al: Czech Pneumological and Phthisiological Society. Chronic Obstructive Pulmonary Disease: Official diagnosis and treatment guidelines of the Czech Pneumological and Phthisiological Society; a novel phenotypic approach to COPD with patient-oriented care. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 157:189–201. 2013.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Wang J, Wang W, Lin H, Huan C, Jiang S, Lin D, Cao N and Ren H: Role of pulmonary function and FeNO detection in early screening of patients with ACO. Exp Ther Med 20: 830-837, 2020.
APA
Wang, J., Wang, W., Lin, H., Huan, C., Jiang, S., Lin, D. ... Ren, H. (2020). Role of pulmonary function and FeNO detection in early screening of patients with ACO. Experimental and Therapeutic Medicine, 20, 830-837. https://doi.org/10.3892/etm.2020.8762
MLA
Wang, J., Wang, W., Lin, H., Huan, C., Jiang, S., Lin, D., Cao, N., Ren, H."Role of pulmonary function and FeNO detection in early screening of patients with ACO". Experimental and Therapeutic Medicine 20.2 (2020): 830-837.
Chicago
Wang, J., Wang, W., Lin, H., Huan, C., Jiang, S., Lin, D., Cao, N., Ren, H."Role of pulmonary function and FeNO detection in early screening of patients with ACO". Experimental and Therapeutic Medicine 20, no. 2 (2020): 830-837. https://doi.org/10.3892/etm.2020.8762
Copy and paste a formatted citation
x
Spandidos Publications style
Wang J, Wang W, Lin H, Huan C, Jiang S, Lin D, Cao N and Ren H: Role of pulmonary function and FeNO detection in early screening of patients with ACO. Exp Ther Med 20: 830-837, 2020.
APA
Wang, J., Wang, W., Lin, H., Huan, C., Jiang, S., Lin, D. ... Ren, H. (2020). Role of pulmonary function and FeNO detection in early screening of patients with ACO. Experimental and Therapeutic Medicine, 20, 830-837. https://doi.org/10.3892/etm.2020.8762
MLA
Wang, J., Wang, W., Lin, H., Huan, C., Jiang, S., Lin, D., Cao, N., Ren, H."Role of pulmonary function and FeNO detection in early screening of patients with ACO". Experimental and Therapeutic Medicine 20.2 (2020): 830-837.
Chicago
Wang, J., Wang, W., Lin, H., Huan, C., Jiang, S., Lin, D., Cao, N., Ren, H."Role of pulmonary function and FeNO detection in early screening of patients with ACO". Experimental and Therapeutic Medicine 20, no. 2 (2020): 830-837. https://doi.org/10.3892/etm.2020.8762
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