Open Access

Clinical efficacy of MVD combined with PSR in the treatment of primary trigeminal neuralgia

  • Authors:
    • Guangyu Zhao
    • Xiaojun Sun
    • Zhen Zhang
    • Hongan Yang
    • Xiangrong Zheng
    • Bin Feng
  • View Affiliations

  • Published online on: June 10, 2020     https://doi.org/10.3892/etm.2020.8871
  • Pages: 1582-1588
  • Copyright: © Zhao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Clinical efficacy of microvascular decompression (MVD) combined with percutaneous stereotactic radiofrequency rhizotomy (PSR) in the treatment of primary trigeminal neuralgia was investigated. The medical records of 141 patients with primary trigeminal neuralgia admitted to Shandong Provincial Hospital from May 2011 to June 2013 were collected. Among them, 63 patients received MVD surgery and were set as group A, while the other 78 received MVD combined with PSR and were as group B. The efficacy and complication of the two treatment methods were compared. Multivariate logistic regression was performed to analyze the risk factors for treatment efficacy. The total effective rate was 96.15% in group B, higher than that in group A (88.89%), but the difference was not statistically significant (P>0.05). The complications in group B were statistically less than that in group A (P<0.05). Risk factors for the onset of primary trigeminal neuralgia included the degree of decompression, duration of disease, degree of compression, and clinical symptoms. Patients treated with MVD combined with PSR had a better quality of life and lower 5-year recurrence rate than patients treated with MVD (both P<0.05). In conclusion, MVD combined with PSR treatment has good clinical efficacy in primary trigeminal neuralgia and low incidence of complications. The possible risk factors for the onset of primary trigeminal neuralgia include the degree of decompression, duration of disease, degree of compression, and clinical symptoms.

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August-2020
Volume 20 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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APA
Zhao, G., Sun, X., Zhang, Z., Yang, H., Zheng, X., & Feng, B. (2020). Clinical efficacy of MVD combined with PSR in the treatment of primary trigeminal neuralgia. Experimental and Therapeutic Medicine, 20, 1582-1588. https://doi.org/10.3892/etm.2020.8871
MLA
Zhao, G., Sun, X., Zhang, Z., Yang, H., Zheng, X., Feng, B."Clinical efficacy of MVD combined with PSR in the treatment of primary trigeminal neuralgia". Experimental and Therapeutic Medicine 20.2 (2020): 1582-1588.
Chicago
Zhao, G., Sun, X., Zhang, Z., Yang, H., Zheng, X., Feng, B."Clinical efficacy of MVD combined with PSR in the treatment of primary trigeminal neuralgia". Experimental and Therapeutic Medicine 20, no. 2 (2020): 1582-1588. https://doi.org/10.3892/etm.2020.8871