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Relationship between chemokines and T lymphocytes in the context of respiratory allergies (Review)

  • Authors:
    • Nicolae Ovidiu Berghi
    • Mihai Dumitru
    • Daniela Vrinceanu
    • Radu Constantin Ciuluvica
    • Anca Simioniuc-Petrescu
    • Ramona Caragheorgheopol
    • Catalin Tucureanu
    • Roxana Sfrent Cornateanu
    • Calin Giurcaneanu
  • View Affiliations / Copyright

    Affiliations: Department of Oncologic Dermatology, ‘Elias’ Emergency University Hospital, ‘Carol Davila’ University of Medicine and Pharmacy, 011461 Bucharest, Romania, Anatomy Department, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, ENT Department, ‘Carol Davila’ University of Medicine and Pharmacy, 010271 Bucharest, Romania, Immunology Laboratory, ‘Cantacuzino’ National Military-Medical Institute for Research and Development, 050096 Bucharest, Romania, Department of Physiopathology and Immunology, ‘Carol Davila’ University of Medicine and Pharmacy, 041914 Bucharest, Romania
    Copyright: © Berghi et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2352-2360
    |
    Published online on: June 29, 2020
       https://doi.org/10.3892/etm.2020.8961
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Abstract

Allergic diseases have been classified in the last decades using various theories. The main classes of the newest classification in allergic respiratory diseases focus on the characterization of the endotype (which takes into account biomarkers related to determinant pathophysiological mechanisms) and of the phenotype (based on the description of the disease). Th2, Th1 and Th17 lymphocytes and the type of inflammatory response mediated by them represent the basis for Th2 and non‑Th2 endotype classification. In addition, new lymphocytes were also used to characterize allergic diseases: Th9 lymphocytes, Th22 lymphocytes, T follicular helper cells (TFh) lymphocytes and invariant natural killer T (iNKT) lymphocytes. In the last decade, a growing body of evidence focused on chemokines, chemoattractant cytokines, which seems to have an important contribution to the pathogenesis of this pathology. This review presents the interactions between chemokines and Th lymphocytes in the context of Th2/non‑Th2 endotype classification of respiratory allergies.
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Copy and paste a formatted citation
Spandidos Publications style
Berghi NO, Dumitru M, Vrinceanu D, Ciuluvica RC, Simioniuc-Petrescu A, Caragheorgheopol R, Tucureanu C, Cornateanu RS and Giurcaneanu C: Relationship between chemokines and T lymphocytes in the context of respiratory allergies (Review). Exp Ther Med 20: 2352-2360, 2020.
APA
Berghi, N.O., Dumitru, M., Vrinceanu, D., Ciuluvica, R.C., Simioniuc-Petrescu, A., Caragheorgheopol, R. ... Giurcaneanu, C. (2020). Relationship between chemokines and T lymphocytes in the context of respiratory allergies (Review). Experimental and Therapeutic Medicine, 20, 2352-2360. https://doi.org/10.3892/etm.2020.8961
MLA
Berghi, N. O., Dumitru, M., Vrinceanu, D., Ciuluvica, R. C., Simioniuc-Petrescu, A., Caragheorgheopol, R., Tucureanu, C., Cornateanu, R. S., Giurcaneanu, C."Relationship between chemokines and T lymphocytes in the context of respiratory allergies (Review)". Experimental and Therapeutic Medicine 20.3 (2020): 2352-2360.
Chicago
Berghi, N. O., Dumitru, M., Vrinceanu, D., Ciuluvica, R. C., Simioniuc-Petrescu, A., Caragheorgheopol, R., Tucureanu, C., Cornateanu, R. S., Giurcaneanu, C."Relationship between chemokines and T lymphocytes in the context of respiratory allergies (Review)". Experimental and Therapeutic Medicine 20, no. 3 (2020): 2352-2360. https://doi.org/10.3892/etm.2020.8961
Copy and paste a formatted citation
x
Spandidos Publications style
Berghi NO, Dumitru M, Vrinceanu D, Ciuluvica RC, Simioniuc-Petrescu A, Caragheorgheopol R, Tucureanu C, Cornateanu RS and Giurcaneanu C: Relationship between chemokines and T lymphocytes in the context of respiratory allergies (Review). Exp Ther Med 20: 2352-2360, 2020.
APA
Berghi, N.O., Dumitru, M., Vrinceanu, D., Ciuluvica, R.C., Simioniuc-Petrescu, A., Caragheorgheopol, R. ... Giurcaneanu, C. (2020). Relationship between chemokines and T lymphocytes in the context of respiratory allergies (Review). Experimental and Therapeutic Medicine, 20, 2352-2360. https://doi.org/10.3892/etm.2020.8961
MLA
Berghi, N. O., Dumitru, M., Vrinceanu, D., Ciuluvica, R. C., Simioniuc-Petrescu, A., Caragheorgheopol, R., Tucureanu, C., Cornateanu, R. S., Giurcaneanu, C."Relationship between chemokines and T lymphocytes in the context of respiratory allergies (Review)". Experimental and Therapeutic Medicine 20.3 (2020): 2352-2360.
Chicago
Berghi, N. O., Dumitru, M., Vrinceanu, D., Ciuluvica, R. C., Simioniuc-Petrescu, A., Caragheorgheopol, R., Tucureanu, C., Cornateanu, R. S., Giurcaneanu, C."Relationship between chemokines and T lymphocytes in the context of respiratory allergies (Review)". Experimental and Therapeutic Medicine 20, no. 3 (2020): 2352-2360. https://doi.org/10.3892/etm.2020.8961
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