Open Access

Proteus syndrome of the foot: A case report and literature review

  • Authors:
    • Min He
    • Weijia Zhao
  • View Affiliations

  • Published online on: July 10, 2020     https://doi.org/10.3892/etm.2020.8986
  • Pages: 2716-2720
  • Copyright: © He et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Proteus syndrome (PS) is an extremely rare and sporadic disorder characterized by asymmetric and/or disproportionate overgrowth of limbs, hamartomas, and vascular malformations. The onset of overgrowth usually involves the skin, bone, fat, and other connective tissues in a patchy or mosaic pattern. Partial gigantism of the affected limb or digit is a pathognomonic sign of PS. Thus far, only a few cases of PS have been recorded in the literature. In the present report, a case of PS in a 35‑year old woman with classic cerebriform plantar hyperplasia and macrodactyly of the left foot was documented. The clinical and molecular characteristics and differential diagnosis of PS are also discussed in this report.

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September-2020
Volume 20 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
He M and He M: Proteus syndrome of the foot: A case report and literature review. Exp Ther Med 20: 2716-2720, 2020
APA
He, M., & He, M. (2020). Proteus syndrome of the foot: A case report and literature review. Experimental and Therapeutic Medicine, 20, 2716-2720. https://doi.org/10.3892/etm.2020.8986
MLA
He, M., Zhao, W."Proteus syndrome of the foot: A case report and literature review". Experimental and Therapeutic Medicine 20.3 (2020): 2716-2720.
Chicago
He, M., Zhao, W."Proteus syndrome of the foot: A case report and literature review". Experimental and Therapeutic Medicine 20, no. 3 (2020): 2716-2720. https://doi.org/10.3892/etm.2020.8986