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Experimental and Therapeutic Medicine
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2026 Volume 31 Issue 3

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Impact Factor: 2.3

Article Open Access

Effect of SGLT2 inhibitors on heart failure outcomes in patients with and without diabetes: A systematic review and meta‑analysis of randomized controlled trials

Duaa Abdullah Bafail, Noura Hamdi Alhalees
Article Number: 84
Published online on: 28 January 2026

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Article Open Access

Exploring the protective mechanisms and therapeutic potential of carnosic acid against acute respiratory distress syndrome through molecular docking, molecular dynamics and experimental verification

Quan Li, Lili Ding, Haijun Sun, Weichao Ding, Mengmeng Wang, Zhaorui Sun, Congxue Ma
Article Number: 83
Published online on: 28 January 2026

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Review

Exploring the roots of schizophrenia: Current research and future directions (Review)

Shuang Lv, Chunxia Luo
Article Number: 82
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] miR‑146a‑5p protects against renal injury in MRL/lpr mice via improvement of the Treg/Th17 imbalance by targeting the TRAF6/NF‑κB axis

Jiajia Teng, Feng Yang, Xiaoling Li
Article Number: 81
Published online on: 28 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑24‑3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl‑2‑like protein 11

Huanxin Zhang, Shizhen Xue, Yi Feng, Jun Shen, Jixian Zhao
Article Number: 80
Published online on: 26 January 2026

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Article Open Access

Efficacy and safety of unilateral biportal endoscopy vs. percutaneous endoscopic interlaminar approach in lumbar disc herniation: A meta‑analysis​

Yuhao Gao, Fangzheng He, Ji Wen, Shilei Qin, Pengfei Han, Yunfeng Xu
Article Number: 79
Published online on: 23 January 2026

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Case Report Open Access

Intralobar pulmonary sequestration coexisting with pulmonary cryptococcosis: A case report and literature review

Dan Cheng, Yue Wang, Jun Li, Dan Yu, Yunyun Wang, Jinbo Fan, Jiankun Wang, Liqun He
Article Number: 78
Published online on: 23 January 2026

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Article Open Access

Tumor‑associated macrophages suppress estrogen receptor‑β expression in triple‑negative breast cancer through the PI3K/AKT pathway

Qiulei Zhang, Di Guo, Gaoran Xu, Rong Xie, Yuqing Deng, Peng Fu, Jinnan Wan
Article Number: 77
Published online on: 21 January 2026

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Article Open Access

Development of a diagnostic model for esophageal achalasia assessed by esophageal high‑resolution manometry using artificial intelligence

Maiko Tabuchi, Yasuhiko Nakao, Hitomi Minami, Hiroko Inomata, Junya Shiota, Taro Akashi, Keiichi Hashiguchi, Moto Kitayama, Kayoko Matsushima, Naoyuki Yamaguchi, Yuko Akazawa, Hisamitsu Miyaaki
Article Number: 76
Published online on: 21 January 2026

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Case Report

Use of metagenomic next‑generation sequencing to diagnose Tropheryma whipplei infection‑related pneumonia: A case report

Yutu Luo, Haibing Ding, Jiahua Pan, Guangyang Xu
Article Number: 75
Published online on: 21 January 2026

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Article Open Access

Effect of rivaroxaban on DNA damage in an ischemia-reperfusion model: Evaluation of 8‑OHdG levels

Ceren Sayarer, Abidin Cenk Erdal, Tuğra Gençpinar, Özlem Gürsoy Doruk, Tuncay Küme
Article Number: 74
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Hepatoprotective activity of chrysin is mediated through TNF‑α in chemically‑induced acute liver damage: An in vivo study and molecular modeling 

Anca Hermenean, Teodora Mariasiu, Inmaculada Navarro-González, Josefina Vegara-Meseguer, Eftimie Miuțescu, Sandipan Chakraborty, Horacio Pérez-Sánchez
Article Number: 73
Published online on: 21 January 2026

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Retraction Open Access

[Retracted] Gambogic acid suppresses colon cancer cell activity in vitro

Zailong Zhou, Jian Ma
Article Number: 72
Published online on: 19 January 2026

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Case Report

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review

Burak Menekse, Enes Ucgul, Abdullatif Bakir, Sema Hepsen, Ilknur Ozturk Unsal, Muhammed Kizilgul, Takako Araki, Erman Cakal
Article Number: 71
Published online on: 16 January 2026

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Case Report Open Access

Postoperative hypofractionated intensity-modulated proton therapy to control recurrent paraganglioma at the jugular foramen: A case report and literature review

Wei Wang, Yingxia Yuan, Jiwei Bai, Yue Zou, Dongxue Zhou, Jun Zhao, Shuyan Zhang, Zishen Wang, Jie Wang, Jingjing Kong, Lu Yang, Masashi Mizumoto, Hideyuki Sakurai, Shosei Shimizu
Article Number: 70
Published online on: 16 January 2026

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Article

Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury

Ruoran Wang, Min He, Jianguo Xu
Article Number: 69
Published online on: 16 January 2026

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Retraction Open Access

[Retracted] β‑asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal‑regulated kinase signaling pathway

Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong Li
Article Number: 68
Published online on: 12 January 2026

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Case Report Open Access

Rare co‑occurrence of gastrointestinal stromal tumors and leiomyomas: A case report and review of the literature

Yu Zhang, Xiaoqiong Shi, Wenfu Xie, Meilin He, Shan Zhang, Xue Peng, Hao Lei, Xulei Li, Haiying Liu, Qiao Shu, Fangyuan Zou, Mingyong Wei
Article Number: 67
Published online on: 09 January 2026

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Article Open Access

No increased risk of hepatic enzyme abnormalities with non‑peptidic thrombopoietin receptor agonists in immune thrombocytopenia: A meta‑analysis of randomized controlled trials

Nan Shen, Rang Wu, Tiantian Lu, Song Liu, Yazhou Jiang, Jingjing Yan, Tao Ning, Chang Dong, Jianqin Li, Suyue Zhu
Article Number: 66
Published online on: 09 January 2026

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Case Report

Submucosal colonic fecalith mimicking a submucosal malignant tumor at the anastomotic site after colon cancer: A case report

Motoaki Yuhi, Masatsugu Hiraki, Shin Takesue, Mariko Hashiguchi, Megumi Nishiyama, Yoshiaki Egashira, Tatsuya Manabe, Hirokazu Noshiro
Article Number: 65
Published online on: 08 January 2026

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Article

Clinical characteristics of acute primary angle closure following COVID‑19 during the Omicron outbreak in China

Jianhui Zhang, Yingying Xue, Liu Zhang, Yuhong Wang, Shancheng Si
Article Number: 64
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Aberrant expression and mechanism of miR‑130b‑3p/phosphatase and tensin homolog in nephroblastoma in children

Yifeng Hu, Jingtie Yan
Article Number: 63
Published online on: 05 January 2026

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.3

Article Open Access

Surgical treatment of extrahepatic intraabdominal hydatid cysts: A single‑centre retrospective analysis

Fatih Dal, Tutkun Talih, Muhammet Akyüz, Uğur Topal, Gökhan Sönmez, Erdoğan Mütevelli Sözüer, Hizir Yakup Akyildiz, Mustafa Karaağaç, Sedat Çarkit, Doğan Gürkan İslam
Article Number: 102
Published online on: 09 February 2026

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Article Open Access

Analysis of independent prognostic factors for the occurrence and severity of heart failure after chemotherapy in patients with small cell lung cancer 

Jieqiong Zhao, Xiao Wang, Xiaoxue Liu, Wei Zhao, Xia Lu, Ruijie Li, Xiang Sun
Article Number: 101
Published online on: 09 February 2026

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Case Report

Sagittal sinus thrombosis in pregnancy: A case report

Zaheera Saadia, Misbah Ilyas, Jayd Saud Althwiny, Fai Alaqel, Alanoud Abdullah Alsufayri, Lujain Husain Almutairi
Article Number: 100
Published online on: 05 February 2026

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Article

Elevated PGE2 and COX‑2 expression in villous adenoma: Implications for electrolyte depletion syndrome

Shiki Fujino, Hiroyuki Fukuda, Katsuki Danno, Takashi Takeda, Masaya Higashiguchi, Kozo Noguchi, Takefumi Hirao, Aya Ito, Norikatsu Miyoshi, Yoshio Oka
Article Number: 99
Published online on: 04 February 2026

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Article Open Access

Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation

Yu Lu, Xiaomei Zhou, Yiyu Guo, Fengrui Zhang, Jirong Wang, Jinhong Ge, Yan Xiao, Dengke Yang
Article Number: 98
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Glibenclamide exacerbates adriamycin‑induced cardiotoxicity by activating oxidative stress‑induced endoplasmic reticulum stress in rats

Meng-Lin Liu, Meng-Long Wang, Jing-Jun Lv, Jie Wei, Jun Wan
Article Number: 97
Published online on: 04 February 2026

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Review

Key role of the autonomic nervous system in breast cancer (Review)

Min Wu, Zhiwu Zhang, Lu Zhou, Shiqi Liu, Qing Chen, Cui Guo, Shasha Zhao, Xuedan Chen
Article Number: 96
Published online on: 04 February 2026

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Review Open Access

Senescent hepatic stellate cells drive inflammation and disease progression in MASH (Review)

Zhiqi Han, Yiran She, Di Wu, Nuo Zhang, Zheyuan Liu, Zhongyuan Wang, Xiaoying Zhou, Shuo Li
Article Number: 95
Published online on: 04 February 2026

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Article Open Access

PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

Zilong Zhang, Hangyu Zhou, Diliyaer Adili, Wei Zhu, Yong Liu, Wenzheng Zhou, Zhao Wang, Jie Li
Article Number: 94
Published online on: 04 February 2026

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Case Report

A novel human papillomavirus‑induced ‘doughnut wart’ lesion treated with 5‑aminolevulinic acid photodynamic therapy: A case report

Ke Li, Yitao Qian, Wenjing Zha, Lei Shi
Article Number: 93
Published online on: 04 February 2026

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Case Report Open Access

Comprehensive diagnosis and individualized treatment of multiple primary lung cancer: A case report

Guoxiong Zeng, Yunyan Zhou, Wang Wan, Biao Deng, Chunyuan Chen, Zhu Liang
Article Number: 92
Published online on: 03 February 2026

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Review Open Access

Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review)

Hong Zhou, Wenwen Yu, Jiaming Lei, Runzhi Chang, Yingjia Cheng, Guorui Wang, Li Lin
Article Number: 91
Published online on: 03 February 2026

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Case Report Open Access

A rare upstream regulatory region mutation in APC presenting as classical familial adenomatous polyposis: A case report and literature review

Chi-Han Yang, Yen-Cheng Chen, Tsung-Kun Chang, Wei-Chih Su, Ching-Wen Huang, Hsiang-Lin Tsai, Jaw-Yuan Wang
Article Number: 90
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] lncRNA MIAT promote cell invasion and migration in esophageal cancer

Weiguo Zhang, Qiang Chen, Caipeng Lei
Article Number: 89
Published online on: 02 February 2026

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Review Open Access

Mitochondria‑driven ferroptosis in intervertebral disc degeneration: A novel target in age‑related spinal diseases (Review)

Yang Hou, Xiaolei Yang, Duorun Qiu, Lei Liu, Jiangang Shi, Yongfei Guo
Article Number: 88
Published online on: 02 February 2026

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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

Jingxian Li, Fang Wang, Yuanshu Du, Yonghui Wang
Article Number: 87
Published online on: 02 February 2026

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Case Report Open Access

Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report

Bin He, Lin Ling Li, Ting Yu, Yu Tan, Ling Zhang
Article Number: 86
Published online on: 29 January 2026

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Article Open Access

Myrrh ameliorates endometriosis by enhancing ER stress‑related apoptotic cell death

Bo-Sung Kim, Minkyoung Cho, Jung Ho Han, Jung-Sook Jin, Sung-Jin Bae, Yunju Jo, Dongryeol Ryu, Yerim Joo, Seon Beom Kim, Jongkil Joo, Inhye Kim, Ki-Tae Ha
Article Number: 85
Published online on: 29 January 2026

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Review Open Access

ERK/MAPK signalling pathway and tumorigenesis (Review)

Yan‑Jun Guo, Wei‑Wei Pan, Sheng‑Bing Liu, Zhong‑Fei Shen, Ying Xu, Ling‑Ling Hu

Pages: 1997-2007
Published online on: 15 January 2020
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Article Open Access

Beneficial effects of dried pomegranate juice concentrated powder on ultraviolet B-induced skin photoaging in hairless mice

Su‑Jin Kang, Beom‑Rak Choi, Seung‑Hee Kim, Hae‑Yeon Yi, Hye‑Rim Park, Chang‑Hyun Song, Sae‑Kwang Ku, Young‑Joon Lee

Pages: 1023-1036
Published online on: 16 June 2017
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Article Open Access

Synergistic inhibitory effects of low‑dose decitabine in combination with bortezomib in the AML cell line Kasumi‑1

Vassiliki Mpakou, Aris Spathis, Anthi Bouhla, Efthimia Mpazani, Sotirios Papageorgiou, Konstantinos Gkontopoulos, Eirini Glezou, Thomas Thomopoulos, Periklis Foukas, Vasiliki Pappa

Article Number: 195
Published online on: 08 January 2021
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Article Open Access

Prevalence of Helicobacter pylori infection among dyspeptic patients in Northwestern Romania: A decreasing epidemiological trend in the last 30 years

Alexandra Loor Corojan, Dan‑Lucian Dumitrașcu, Petrică Ciobanca, Daniel‑Corneliu Leucuta

Pages: 3488-3492
Published online on: 17 July 2020
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Article

New treatment strategies for uterine sarcoma using secreted frizzled‑related proteins

Tomohiro Kagawa, Ayuka Mineda, Tomotaka Nakagawa, Ayaka Shinohara, Ryosuke Arakaki, Hiroaki Inui, Hiroki Noguchi, Atsuko Yoshida, Riyo Kinouchi, Yuri Yamamoto, Kanako Yoshida, Takashi Kaji, Masato Nishimura, Takeshi Iwasa

Article Number: 231
Published online on: 26 March 2024
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Article Open Access

Lung histomorphological alterations in rats exposed to cigarette smoke and electronic cigarette vapour

Ewelina Wawryk‑Gawda, Patrycja Chylińska‑Wrzos, Michał K. Zarobkiewicz, Katarzyna Chłapek, Barbara Jodłowska‑Jędrych

Pages: 2826-2832
Published online on: 17 February 2020
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Article

Prebiotics and probiotics in atopic dermatitis (Review)

Emilia Rusu, Georgiana Enache, Raluca Cursaru, Alexandra Alexescu, Raluca Radu, Oana Onila, Teodora Cavallioti, Florin Rusu, Mihaela Posea, Mariana Jinga, Gabriela Radulian

Pages: 926-931
Published online on: 14 June 2019
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Article

Triterpenoids from Ganoderma lucidum inhibit the activation of EBV antigens as telomerase inhibitors

Dong‑Shu Zheng, Liang‑Shu Chen

Pages: 3273-3278
Published online on: 03 August 2017
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Review

Benefits of crenotherapy in digestive tract pathology (Review)

Magdalena Dumitrescu, Madalina Gabriela Iliescu, Laura Mazilu, Sergiu Ioan Micu, Adrian Paul Suceveanu, Felix Voinea, Claudia Voinea, Anca Pantea Stoian, Andra-Iulia Suceveanu

Article Number: 122
Published online on: 07 December 2021
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Article Open Access

Efficacy of Sildenafil on healthy humans in high‑altitude hypoxia at rest and during exercise: A meta‑analysis

Zhan-Cui Dang, Zhiquan Yang, Shou Liu, Guo-Mei Du, Linde Jin, Zhong-Zhi Zhao

Article Number: 88
Published online on: 08 January 2024
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Article

Elevated levels of alanine transaminase and triglycerides within normal limits are associated with fatty liver

Minoru Tomizawa, Yuji Kawanabe, Fuminobu Shinozaki, Sumihiko Sato, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Makoto Sueishi

Pages: 759-762
Published online on: 23 June 2014
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Article

Photoprotective and immunoregulatory capacity of ginsenoside Rg1 in chronic ultraviolet B-irradiated BALB/c mouse skin

Jin-Shu Lou, Xiao-E Chen, Yan Zhang, Zuo-Wen Gao, Tai-Ping Chen, Guo‑Qiang Zhang, Chang Ji

Pages: 1022-1028
Published online on: 25 July 2013
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Article

Immunohistochemical analysis of collagen expression in uterine leiomyomata during the menstrual cycle

Masaaki Iwahashi, Yasuteru Muragaki, Makoto Ikoma, Yasushi Mabuchi, Aya Kobayashi, Yuuko Tanizaki, Kazuhiko Ino

Pages: 287-290
Published online on: 05 January 2011
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Article

Hpyerglycemic and anti-diabetic nephritis activities of polysaccharides separated from Auricularia auricular in diet-streptozotocin-induced diabetic rats

Xinyu Hu, Chungang Liu, Xue Wang, Dongxu Jia, Wenqian Lu, Xiaoqi Sun, Yang Liu, Lijia Yuan

Pages: 352-358
Published online on: 01 December 2016
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Article Open Access

Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in the hair cycle

Chun Hou, Yong Miao, Xue Wang, Chaoyue Chen, Bojie Lin, Zhiqi Hu

Pages: 231-237
Published online on: 09 May 2016
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Article Open Access

Dandelion root extracts and taraxasterol inhibit LPS‑induced colorectal cancer cell viability by blocking TLR4‑NFκB‑driven ACE2 and TMPRSS2 pathways

Kerry Yang, Yuehong Wang

Article Number: 256
Published online on: 19 April 2024
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Article Open Access

Medicinal mushroom Phellinus linteus as an alternative cancer therapy (Review)

Daniel Sliva

Pages: 407-411
Published online on: 01 May 2010
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Article

Ostrich produce cross-reactive neutralization antibodies against pandemic influenza virus A/H1N1 following immunization with a seasonal influenza vaccine

Kazuhide Adachi, Kentaro Takama, Masaya Tsukamoto, Marie Inai, Ekowati Handharyani, Satoshi Hiroi, Yasuhiro Tsukamoto

Pages: 41-45
Published online on: 02 December 2010
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Review

Non-sexual HPV transmission and role of vaccination for a better future (Review)

Aida Petca, Andreea Borislavschi, Mona Elena Zvanca, Razvan-Cosmin Petca, Florica Sandru, Mihai Cristian Dumitrascu

Article Number: 186
Published online on: 13 October 2020
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Review Open Access

Nutrient insufficiencies and deficiencies involved in the pathogenesis of bruxism (Review)

Ioannis A. Pavlou, Demetrios A. Spandidos, Vassilis Zoumpourlis, Maria Adamaki

Article Number: 563
Published online on: 19 October 2023
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