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Cardiac CT scanning in coronary artery disease: Epicardial fat volume and its correlation with coronary artery lesions and left ventricular function

  • Authors:
    • Ruohan Yin
    • Xiaoqiang Tang
    • Tao Wang
    • Haifeng Shi
    • Xiang Wang
    • Xiaoqin Wang
    • Changjie Pan
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, Jiangsu 213164, P.R. China
    Copyright: © Yin et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2961-2968
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    Published online on: July 28, 2020
       https://doi.org/10.3892/etm.2020.9064
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Abstract

Coronary artery disease (CAD) is a major and common disease that poses a threat to human health. Recent studies suggested that epicardial fat may have an important role in the pathogenesis of CAD. Therefore, the association between epicardial fat volume (EFV) and left ventricular function with CAD was investigated in the present study. A total of 61 patients with suspected CAD who underwent CT scanning were enrolled. Baseline data, parameters of left heart function and EFV of the subjects were collected and analyzed. The degree of coronary artery lesions was assessed using the Gensini score. Pearson's correlation analysis and a logistic regression model were applied to assess the association between EFV and risk factors for CAD, the Gensini score and left ventricular function index. A total of 29 female and 32 male subjects with a median age of 63 years were enrolled. The median body mass index (BMI) of the subjects was 23.37 kg/m2 and the median EFV was 86.41 cm3. It was revealed that risk factors of CAD, specially hypertension, diabetes mellitus, dyslipidemia, history of myocardial infarction and smoking, had no significant association with the EFV (P>0.05); however, the EFV was significantly positively correlated with the BMI (r=0.479, P<0.0001), interventricular septal thickness (r=0.436, P=0.004), left ventricular posterior wall thickness (r=0.350, P=0.0058), left ventricular end diastolic diameter (r=0.265, P=0.0388), left ventricular mass (r=0.445, P=0.0003) and left ventricular mass index (r=0.371, P=0.0035). However, no correlation was identified between the EFV and the Gensini score (r=0.131, P=0.3137). In conclusion, the EFV measured by cardiac CT scanning was positively correlated with the BMI and left ventricular function, but was not associated with the presence of CAD according to the Gensini scores.
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1 

Potz BA, Parulkar AB, Abid RM, Sodha NR and Sellke FW: Novel molecular targets for coronary angiogenesis and ischemic heart disease. Coron Artery Dis. 28:605–613. 2017.PubMed/NCBI View Article : Google Scholar

2 

Marateb HR and Goudarzi S: A noninvasive method for coronary artery diseases diagnosis using a clinically-interpretable fuzzy rule-based system. J Res Med Sci. 20:214–223. 2015.PubMed/NCBI

3 

Olie RH, van der Meijden PEJ and Ten Cate H: The coagulation system in atherothrombosis: Implications for new therapeutic strategies. Res Pract Thromb Haemost. 2:188–198. 2018.PubMed/NCBI View Article : Google Scholar

4 

Goyal V, Jassal DS and Dhalla NS: Pathophysiology and prevention of sudden cardiac death. Can J Physiol Pharmacol. 94:237–244. 2016.PubMed/NCBI View Article : Google Scholar

5 

Zulkifli Amin H, Zulkifli Amin L and Zulkifli Amin F: Paramount importance of angiotensin receptor neprilysin inhibitor in heart failure management. Acta Med Iran. 54:823–824. 2016.PubMed/NCBI

6 

Han D, Lee JH, Hartaigh BO and Min JK: Role of computed tomography screening for detection of coronary artery disease. Clin Imaging. 40:307–310. 2016.PubMed/NCBI View Article : Google Scholar

7 

Dalager MG, Bøttcher M, Thygesen J, Andersen G and Bøtker HE: Different plaque composition and progression in patients with stable and unstable coronary syndromes evaluated by cardiac CT. Biomed Res Int. 2015(401357)2015.PubMed/NCBI View Article : Google Scholar

8 

Saba L, Anzidei M, Piga M, Ciolina F, Mannelli L, Catalano C, Suri JS and Raz E: Multi-modal CT scanning in the evaluation of cerebrovascular disease patients. Cardiovasc Diagn Ther. 4:245–262. 2014.PubMed/NCBI View Article : Google Scholar

9 

Matsuzawa Y: The metabolic syndrome and adipocytokines. Expert Rev Clin Immunol. 3:39–46. 2007.PubMed/NCBI View Article : Google Scholar

10 

Vidal H: Obesity and inflammation: The adipocytokines. Ann Endocrinol (Paris). 64:S40–S44. 2003.PubMed/NCBI(In French).

11 

Vacca M, Di Eusanio M, Cariello M, Graziano G, D'Amore S, Petridis FD, D'orazio A, Salvatore L, Tamburro A, Folesani G, et al: Integrative miRNA and whole-genome analyses of epicardial adipose tissue in patients with coronary atherosclerosis. Cardiovasc Res. 109:228–239. 2016.PubMed/NCBI View Article : Google Scholar

12 

Fitzgibbons TP and Czech MP: Epicardial and perivascular adipose tissues and their influence on cardiovascular disease: Basic mechanisms and clinical associations. J Am Heart Assoc. 3(e000582)2014.PubMed/NCBI View Article : Google Scholar

13 

Yang TT, Fish AF, Kong WM, Gao X, Huang J, Feng JT, Zhu JY, Chen T and Lou QQ: Correlates of pericardial adipose tissue volume using multidetector CT scanning in cardiac patients in China. Int J Cardiol. 244:285–289. 2017.PubMed/NCBI View Article : Google Scholar

14 

Nagy E, Jermendy AL, Merkely B and Maurovich-Horvat P: Clinical importance of epicardial adipose tissue. Arch Med Sci. 13:864–874. 2017.PubMed/NCBI View Article : Google Scholar

15 

Kitagawa T, Yamamoto H, Sentani K, Takahashi S, Tsushima H, Senoo A, Yasui W, Sueda T and Kihara Y: The relationship between inflammation and neoangiogenesis of epicardial adipose tissue and coronary atherosclerosis based on computed tomography analysis. Atherosclerosis. 243:293–299. 2015.PubMed/NCBI View Article : Google Scholar

16 

Bertaso AG, Bertol D, Duncan BB and Foppa M: Epicardial fat: Definition, measurements and systematic review of main outcomes. Arq Bras Cardiol. 101:e18–e28. 2013.PubMed/NCBI View Article : Google Scholar : (In English, Portuguese).

17 

Fatma E, Bunyamin K, Savas S, Mehmet U, Selma Y, Ismail B, Sabri C, Gulzade O, Ibrahim D and Mehmet Y: Epicardial fat thickness in patients with rheumatoid arthritis. Afr Health Sci. 15:489–495. 2015.PubMed/NCBI View Article : Google Scholar

18 

Kocyigit I, Gungor O, Unal A, Yasan M, Orscelik O, Tunca O, Eroglu E, Sipahioglu MH, Tokgoz B, Ozdogru I, et al: A low serum free triiodothyronine level is associated with epicardial adipose tissue in peritoneal dialysis patients. J Atheroscler Thromb. 21:1066–1074. 2014.PubMed/NCBI View Article : Google Scholar

19 

Hartiala O, Magnussen CG, Bucci M, Kajander S, Knuuti J, Ukkonen H, Saraste A, Rinta-Kiikka I, Kainulainen S, Kähönen M, et al: Coronary heart disease risk factors, coronary artery calcification and epicardial fat volume in the Young Finns Study. Eur Heart J Cardiovasc Imaging. 16:1256–1263. 2015.PubMed/NCBI View Article : Google Scholar

20 

Wu J, Zhang X, Li X and Yang L: Adipose tissue volume differences around the heart between subjects without coronary atherosclerosis and coronary heart disease patients. Acta Cardiol. 71:291–298. 2016.PubMed/NCBI View Article : Google Scholar

21 

Sironi AM, Petz R, De Marchi D, Buzzigoli E, Ciociaro D, Positano V, Lombardi M, Ferrannini E and Gastaldelli A: Impact of increased visceral and cardiac fat on cardiometabolic risk and disease. Diabet Med. 29:622–627. 2012.PubMed/NCBI View Article : Google Scholar

22 

Taylor AJ, Cerqueira M, Hodgson JM, Mark D, Min J, O'Gara P and Rubin GD: American College of Cardiology Foundation Appropriate Use Criteria Task Force; Society of Cardiovascular Computed Tomography; American College of Radiology et al. ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 appropriate use criteria for cardiac computed tomography. A report of the American College of Cardiology Foundation appropriate use criteria task force, the society of cardiovascular computed tomography, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the American Society of Nuclear Cardiology, the North American Society for cardiovascular imaging, the society for cardiovascular angiography and interventions, and the society for cardiovascular magnetic resonance. J Am Coll Cardiol. 56:1864–1894. 2010.PubMed/NCBI View Article : Google Scholar

23 

Gensini GG: A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol. 51(606)1983.PubMed/NCBI View Article : Google Scholar

24 

Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, Gutgesell H, Reichek N, Sahn D, Schnittger I, et al: Recommendations for quantitation of the left ventricle by two-dimensional echocardiography American Society of Echocardiography Committee on standards, subcommittee on quantitation of two-dimensional echocardiograms. J Am Soc Echocardiogr. 2:358–367. 1989.PubMed/NCBI View Article : Google Scholar

25 

Wang G, Li Y, Peng Y, Tang J and Li H: Association of polymorphisms in MALAT1 with risk of coronary atherosclerotic heart disease in a Chinese population. Lipids Health Dis. 17(75)2018.PubMed/NCBI View Article : Google Scholar

26 

Hajar R: Diabetes as ʻcoronary artery disease risk equivalentʼ: A historical perspective. Heart Views. 18:34–37. 2017.PubMed/NCBI View Article : Google Scholar

27 

Florido R, Zhao D, Ndumele CE, Lutsey PL, McEvoy JW, Windham BG, Pankow JS, Guallar E and Michos ED: Physical activity, parental history of premature coronary heart disease, and incident atherosclerotic cardiovascular disease in the atherosclerosis risk in communities (ARIC) study. J Am Heart Assoc. 5(e003505)2016.PubMed/NCBI View Article : Google Scholar

28 

Aydin AM, Kayali A, Poyraz AK and Aydin K: The relationship between coronary artery disease and pericoronary epicardial adipose tissue thickness. J Int Med Res. 43:17–25. 2015.PubMed/NCBI View Article : Google Scholar

29 

Topaloglu O, Sayki Arslan M, Turak O, Ginis Z, Sahin M, Cebeci M, Ucan B, Cakir E, Karbek B, Ozbek M, et al: Three noninvasive methods in the evaluation of subclinical cardiovascular disease in patients with acromegaly: Epicardial fat thickness, aortic stiffness and serum cell adhesion molecules. Clin Endocrinol (Oxf). 80:726–734. 2014.PubMed/NCBI View Article : Google Scholar

30 

Tanaka K and Sata M: Roles of perivascular adipose tissue in the pathogenesis of atherosclerosis. Front Physiol. 9(3)2018.PubMed/NCBI View Article : Google Scholar

31 

Izgi C: Epicardial adipose tissue: Just a predictor or a local player for coronary atherosclerosis? Anatol J Cardiol. 15:360–362. 2015.PubMed/NCBI View Article : Google Scholar

32 

Douglass E, Greif S and Frishman WH: Epicardial fat: Pathophysiology and clinical significance. Cardiol Rev. 25:230–235. 2017.PubMed/NCBI View Article : Google Scholar

33 

Yuce G, Türkvatan A and Yener Ö: Can aortic atherosclerosis or epicardial adipose tissue volume be used as a marker for predicting coronary artery disease? J Cardiol. 65:143–149. 2015.PubMed/NCBI View Article : Google Scholar

34 

Romijn MA, Danad I, Bakkum MJ, Stuijfzand WJ, Tulevski II, Somsen GA, Lammertsma AA, van Kuijk C, van de Ven PM, Min JK, et al: Incremental diagnostic value of epicardial adipose tissue for the detection of functionally relevant coronary artery disease. Atherosclerosis. 242:161–166. 2015.PubMed/NCBI View Article : Google Scholar

35 

Kim SH, Chung JH, Kwon BJ, Song SW and Choi WS: The associations of epicardial adipose tissue with coronary artery disease and coronary atherosclerosis. Int Heart J. 55:197–203. 2014.PubMed/NCBI View Article : Google Scholar

36 

Ghaderi F, Eshraghi A, Shamloo AS and Mousavi S: Assosiation of epicardial and pericardial fat thickness with coronary artery disease. Electron Physician. 8:2982–2989. 2016.PubMed/NCBI View Article : Google Scholar

37 

Yang C, Li L, Zha Y and Peng Z: Correlation between epicardial adipose tissue and severity of coronary artery stenosis evaluated by 64-MDCT. Clin Imaging. 40:477–480. 2016.PubMed/NCBI View Article : Google Scholar

38 

Tanami Y, Jinzaki M, Kishi S, Matheson M, Vavere AL, Rochitte CE, Dewey M, Chen MY, Clouse ME, Cox C, et al: Lack of association between epicardial fat volume and extent of coronary artery calcification, severity of coronary artery disease, or presence of myocardial perfusion abnormalities in a diverse, symptomatic patient population: Results from the CORE320 multicenter study. Circ Cardiovasc Imaging. 8(e002676)2015.PubMed/NCBI View Article : Google Scholar

39 

Bo X, Ma L, Fan J, Jiang Z, Zhou Y, Zhang L and Li W: Epicardial fat volume is correlated with coronary lesion and its severity. Int J Clin Exp Med. 8:4328–4334. 2015.PubMed/NCBI

40 

Hell MM, Ding X, Rubeaux M, Slomka P, Gransar H, Terzopoulos D, Hayes S, Marwan M, Achenbach S, Berman DS and Dey D: Epicardial adipose tissue volume but not density is an independent predictor for myocardial ischemia. J Cardiovasc Comput Tomogr. 10:141–149. 2016.PubMed/NCBI View Article : Google Scholar

41 

Hajsadeghi F, Nabavi V, Bhandari A, Choi A, Vincent H, Flores F, Budoff M and Ahmadi N: Increased epicardial adipose tissue is associated with coronary artery disease and major adverse cardiovascular events. Atherosclerosis. 237:486–489. 2014.PubMed/NCBI View Article : Google Scholar

42 

Mahabadi AA, Berg MH, Lehmann N, Kälsch H, Bauer M, Kara K, Dragano N, Moebus S, Jöckel KH, Erbel R and Möhlenkamp S: Association of epicardial fat with cardiovascular risk factors and incident myocardial infarction in the general population: The Heinz Nixdorf Recall Study. J Am Coll Cardiol. 61:1388–1395. 2013.PubMed/NCBI View Article : Google Scholar

43 

Hachiya K, Fukuta H, Wakami K, Goto T, Tani T and Ohte N: Relation of epicardial fat to central aortic pressure and left ventricular diastolic function in patients with known or suspected coronary artery disease. Int J Cardiovasc Imaging. 30:1393–1398. 2014.PubMed/NCBI View Article : Google Scholar

44 

Sinha SK, Thakur R, Jha MJ, Goel A, Kumar V, Kumar A, Mishra V, Varma CM, Krishna V, Singh AK and Sachan M: Epicardial adipose tissue thickness and its association with the presence and severity of coronary artery disease in clinical setting: A cross-sectional observational study. J Clin Med Res. 8:410–419. 2016.PubMed/NCBI View Article : Google Scholar

45 

Antonopoulos AS, Oikonomou EK, Antoniades C and Tousoulis D: From the BMI paradox to the obesity paradox: The obesity-mortality association in coronary heart disease. Obes Rev. 17:989–1000. 2016.PubMed/NCBI View Article : Google Scholar

46 

Sharma S, Batsis JA, Coutinho T, Somers VK, Hodge DO, Carter RE, Sochor O, Kragelund C, Kanaya AM, Zeller M, et al: Normal-weight central obesity and mortality risk in older adults with coronary artery disease. Mayo Clin Proc. 91:343–351. 2016.PubMed/NCBI View Article : Google Scholar

47 

Sequeira DI, Ebert LC, Flach PM, Ruder TD, Thali MJ and Ampanozi G: The correlation of epicardial adipose tissue on postmortem CT with coronary artery stenosis as determined by autopsy. Forensic Sci Med Pathol. 11:186–192. 2015.PubMed/NCBI View Article : Google Scholar

48 

Shaheen S, Hassan N, Awan M, Zehra N and Manzoor A: Epicardial adipose tissue (EAT) thickness and its association with BMI and waist circumference in healthy adults and coronary artery disease (CAD) patients. Br J Med Med Res. 11:1–10. 2016.

49 

Iacobellis G, Mohseni M, Bianco SD and Banga PK: Liraglutide causes large and rapid epicardial fat reduction. Obesity (Silver Spring). 25:311–316. 2017.PubMed/NCBI View Article : Google Scholar

50 

Fontes-Carvalho R, Fontes-Oliveira M, Sampaio F, Mancio J, Bettencourt N, Teixeira M, Rocha Gonçalves F, Gama V and Leite-Moreira A: Influence of epicardial and visceral fat on left ventricular diastolic and systolic functions in patients after myocardial infarction. Am J Cardiol. 114:1663–1669. 2014.PubMed/NCBI View Article : Google Scholar

51 

Ng AC, Goo SY, Roche N, van der Geest RJ and Wang WY: Epicardial adipose tissue volume and left ventricular myocardial function using 3-dimensional speckle tracking echocardiography. Can J Cardiol. 32:1485–1492. 2016.PubMed/NCBI View Article : Google Scholar

52 

Wang Y, Ma H, Hao X, Yang J, Chen Q, Lu L and Zhang R: Low serum calcium is associated with left ventricular systolic dysfunction in a Chinese population with coronary artery disease. Sci Rep. 6(22283)2016.PubMed/NCBI View Article : Google Scholar

53 

Topuz M and Dogan A: The effect of epicardial adipose tissue thickness on left ventricular diastolic functions in patients with normal coronary arteries. Kardiol Pol. 75:196–203. 2017.PubMed/NCBI View Article : Google Scholar

54 

Kırış A, Kırış G, Turan OE, Öztürk M, Şahin M, İlter A, Bektaş O, Kutlu M, Kaplan Ş and Gedikli Ö: Relationship between epicardial fat tissue and left ventricular synchronicity: An observational study. Anatol J Cardiol. 15:990–994. 2015.PubMed/NCBI View Article : Google Scholar

55 

Bakkum MJ, Danad I, Romijn MA, Stuijfzand WJ, Leonora RM, Tulevski II, Somsen GA, Lammertsma AA, van Kuijk C, van Rossum AC, et al: The impact of obesity on the relationship between epicardial adipose tissue, left ventricular mass and coronary microvascular function. Eur J Nucl Med Mol Imaging. 42:1562–1573. 2015.PubMed/NCBI View Article : Google Scholar

56 

Doğan M, Turak O, Akyel A, Grboviç E, Mendi MA, Oksüz F, Doğan A, Cimen T, Bilgin M, Sunman H, et al: Increased epicardial adipose tissue thickness is linked to aortic stiffness in patients with primary hypertension. Blood Press. 23:222–227. 2014.PubMed/NCBI View Article : Google Scholar

57 

Vural M, Talu A, Sahin D, Elalmis OU, Durmaz HA, Uyanık S and Dolek BA: Evaluation of the relationship between epicardial fat volume and left ventricular diastolic dysfunction. Jpn J Radiol. 32:331–339. 2014.PubMed/NCBI View Article : Google Scholar

58 

Nerlekar N, Muthalaly RG, Wong N, Thakur U, Wong DTL, Brown AJ and Marwick TH: Association of volumetric epicardial adipose tissue quantification and cardiac structure and function. J Am Heart Assoc. 7(e009975)2018.PubMed/NCBI View Article : Google Scholar

59 

Fernandes-Cardoso A, Santos-Furtado M, Grindler J, Ferreira LA, Andrade JL and Santo MA: Epicardial fat thickness correlates with P-wave duration, left atrial size and decreased left ventricular systolic function in morbid obesity. Nutr Metab Cardiovasc Dis. 27:731–738. 2017.PubMed/NCBI View Article : Google Scholar

60 

Kankaanpää M, Lehto HR, Pärkkä JP, Komu M, Viljanen A, Ferrannini E, Knuuti J, Nuutila P, Parkkola R and Iozzo P: Myocardial triglyceride content and epicardial fat mass in human obesity: Relationship to left ventricular function and serum free fatty acid levels. J Clin Endocrinol Metab. 91:4689–4695. 2006.PubMed/NCBI View Article : Google Scholar

61 

Lin HH, Lee JK, Yang CY, Lien YC, Huang JW and Wu CK: Accumulation of epicardial fat rather than visceral fat is an independent risk factor for left ventricular diastolic dysfunction in patients undergoing peritoneal dialysis. Cardiovasc Diabetol. 12(127)2013.PubMed/NCBI View Article : Google Scholar

62 

Peng-Hui Jian L-FX and Tie-Jun Zhang: Study on ultrasound evaluation of carotid atherosclerosis and its predicting value for coronary heart disease. 22 12: 4, 2016.

63 

Neeland IJ, Ayers CR, Rohatgi AK, Turer AT, Berry JD, Das SR, Vega GL, Khera A, McGuire DK, Grundy SM and de Lemos JA: Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults. Obesity (Silver Spring). 21:E439–E447. 2013.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Yin R, Tang X, Wang T, Shi H, Wang X, Wang X and Pan C: Cardiac CT scanning in coronary artery disease: Epicardial fat volume and its correlation with coronary artery lesions and left ventricular function. Exp Ther Med 20: 2961-2968, 2020.
APA
Yin, R., Tang, X., Wang, T., Shi, H., Wang, X., Wang, X., & Pan, C. (2020). Cardiac CT scanning in coronary artery disease: Epicardial fat volume and its correlation with coronary artery lesions and left ventricular function. Experimental and Therapeutic Medicine, 20, 2961-2968. https://doi.org/10.3892/etm.2020.9064
MLA
Yin, R., Tang, X., Wang, T., Shi, H., Wang, X., Wang, X., Pan, C."Cardiac CT scanning in coronary artery disease: Epicardial fat volume and its correlation with coronary artery lesions and left ventricular function". Experimental and Therapeutic Medicine 20.4 (2020): 2961-2968.
Chicago
Yin, R., Tang, X., Wang, T., Shi, H., Wang, X., Wang, X., Pan, C."Cardiac CT scanning in coronary artery disease: Epicardial fat volume and its correlation with coronary artery lesions and left ventricular function". Experimental and Therapeutic Medicine 20, no. 4 (2020): 2961-2968. https://doi.org/10.3892/etm.2020.9064
Copy and paste a formatted citation
x
Spandidos Publications style
Yin R, Tang X, Wang T, Shi H, Wang X, Wang X and Pan C: Cardiac CT scanning in coronary artery disease: Epicardial fat volume and its correlation with coronary artery lesions and left ventricular function. Exp Ther Med 20: 2961-2968, 2020.
APA
Yin, R., Tang, X., Wang, T., Shi, H., Wang, X., Wang, X., & Pan, C. (2020). Cardiac CT scanning in coronary artery disease: Epicardial fat volume and its correlation with coronary artery lesions and left ventricular function. Experimental and Therapeutic Medicine, 20, 2961-2968. https://doi.org/10.3892/etm.2020.9064
MLA
Yin, R., Tang, X., Wang, T., Shi, H., Wang, X., Wang, X., Pan, C."Cardiac CT scanning in coronary artery disease: Epicardial fat volume and its correlation with coronary artery lesions and left ventricular function". Experimental and Therapeutic Medicine 20.4 (2020): 2961-2968.
Chicago
Yin, R., Tang, X., Wang, T., Shi, H., Wang, X., Wang, X., Pan, C."Cardiac CT scanning in coronary artery disease: Epicardial fat volume and its correlation with coronary artery lesions and left ventricular function". Experimental and Therapeutic Medicine 20, no. 4 (2020): 2961-2968. https://doi.org/10.3892/etm.2020.9064
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