Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
December-2020 Volume 20 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
December-2020 Volume 20 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Assessment of sun‑related behavior and serum vitamin D in basal cell carcinoma: Preliminary results

  • Authors:
    • Corina Vornicescu
    • Loredana Ungureanu
    • Simona Corina Șenilă
    • Ștefan Cristian Vesa
    • Rodica Cosgarea
    • Corina Iulia Baican
    • Mihaela Carmen Mihu
  • View Affiliations / Copyright

    Affiliations: Department of Morphological Sciences‑Histology, ‘Iuliu Hațieganu’ University of Medicine and Pharmacy, 400012 Cluj‑Napoca, Romania, Department of Dermatology, ‘Iuliu Hațieganu’ University of Medicine and Pharmacy, 400012 Cluj‑Napoca, Romania, Department of Pharmacology, Toxicology and Clinical Pharmacology, ‘Iuliu Hațieganu’ University of Medicine and Pharmacy, 400012 Cluj‑Napoca, Romania
    Copyright: © Vornicescu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 187
    |
    Published online on: October 13, 2020
       https://doi.org/10.3892/etm.2020.9317
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Ultraviolet radiation (UV), mainly from sunlight, is the main risk factor of the most common human skin cancer, basal cell carcinoma (BCC). A positive effect of UV on the skin is its contribution to the synthesis of vitamin D, which is important in sustaining general health, but having high levels of vitamin D is considered a risk factor for BCC. However, vitamin D receptor has antagonistic effects to UV radiation in regulating Sonic Hedgehog pathway. This is a pilot study aimed at characterizing the sun‑related behavior and vitamin D status of 52 BCC patients and 59 controls from our geographical area. Patients were included in 4 subgroups: Single, multiple, recurrent, and both multiple and recurrent BCCs. Patients, more than controls, had at least one sunburn in childhood and lentigines (P<0.001). Also, they spent daily, on average, more time in the sun than controls (P<0.001) (3.00‑8.00 and 1.50‑4.00 h respectively). Outdoor work was similar in both groups. Participants had lower vitamin D serum levels than expected. Due to the small number of cases, no statistically significant differences were found between the subgroups but some tendencies were noted. Patients with only one recurrent BCC had less sunburns than the ones who also developed tumors at multiple sites (P=0.2). Patients with multiple and recurrent tumors had slightly lower vitamin D levels compared with single BCC patients (P=0.1) although they used more vitamin D supplements after the BCC diagnosis (P=0.2). Having a diagnosis of BCC, made patients more compliant to the use of sunscreen cream, but even so, half of them still did not use it. In conclusion, more effort should be invested in sun‑related education and public health actions should focus on vitamin D deficiencies.
View Figures
View References

1 

Lomas A, Leonardi-Bee J and Bath-Hextall F: A systematic review of worldwide incidence of nonmelanoma skin cancer. Br J Dermatol. 166:1069–1080. 2012.PubMed/NCBI View Article : Google Scholar

2 

Lupu M, Caruntu C, Popa MI, Voiculescu VM, Zurac S and Boda D: Vascular patterns in basal cell carcinoma: Dermoscopic, confocal and histopathological perspectives. Oncol Lett. 17:4112–4125. 2019.PubMed/NCBI View Article : Google Scholar

3 

Ilie MA, Caruntu C, Lupu M, Lixandru D, Tampa M, Georgescu SR, Bastian A, Constantin C, Neagu M, Zurac SA and Boda D: Current and future applications of confocal laser scanning microscopy imaging in skin oncology. Oncol Lett. 17:4102–4111. 2019.PubMed/NCBI View Article : Google Scholar

4 

Lupu M, Popa IM, Voiculescu VM, Boda D, Caruntu C, Zurac S and Giurcaneanu C: A retrospective study of the diagnostic accuracy of in vivo reflectance confocal microscopy for basal cell carcinoma diagnosis and subtyping. J Clin Med. 8(449)2019.PubMed/NCBI View Article : Google Scholar

5 

Small J, Barton V, Peterson B and Alberg AJ: Keratinocyte carcinoma as a marker of a high cancer-risk phenotype. Adv Cancer Res. 130:257–291. 2016.PubMed/NCBI View Article : Google Scholar

6 

Leiter U and Garbe C: Epidemiology of melanoma and nonmelanoma skin cancer - the role of sunlight. Adv Exp Med Biol. 624:89–103. 2008.PubMed/NCBI View Article : Google Scholar

7 

Reinau D, Surber C, Jick SS and Meier CR: Epidemiology of basal cell carcinoma in the United Kingdom: Incidence, lifestyle factors, and comorbidities. Br J Cancer. 111:203–206. 2014.PubMed/NCBI View Article : Google Scholar

8 

Neamtiu I, Bloom MS, Gati G, Goessler W, Surdu S, Pop C, Braeuer S, Fitzgerald EF, Baciu C, Lupsa IR, et al: Pregnant women in Timis county, Romania are exposed primarily to low-level (<10 µg/l) arsenic through residential drinking water consumption. Int J Hyg Environ Health. 218:371–379. 2015.PubMed/NCBI View Article : Google Scholar

9 

Iannacone MR, Gheit T, Waterboer T, Giuliano AR, Messina JL, Fenske NA, Cherpelis BS, Sondak VK, Roetzheim RG, Ferrer-Gil S, et al: Case-control study of cutaneous human papillomavirus infection in basal cell carcinoma of the skin. J Invest Dermatol. 133:1512–1520. 2013.PubMed/NCBI View Article : Google Scholar

10 

Rotaru M, Iancu G, Mihalache M, Anton G and Morariu S: α-HPV positivity analysis in a group of patients with melanoma and non-melanoma skin cancers. Rev Rom Med Lab: Dec 30, 2014 (Epub ahead of print). doi: urihttps://doi.org/10.2478/rrlm-2014-0044simplehttps://doi.org/10.2478/rrlm-2014-0044.

11 

Holick MF and Chen TC: Vitamin D deficiency: A worldwide problem with health consequences. Am J Clin Nutr. 87:1080S–1086S. 2008.PubMed/NCBI View Article : Google Scholar

12 

Bersani FS, Ghezzi F, Maraone A, Vicinanza R, Cavaggioni G, Biondi M and Pasquini M: The relationship between vitamin D and depressive disorders. Riv Psichiatr. 54:229–234. 2019.PubMed/NCBI View Article : Google Scholar

13 

Holick MF: Vitamin D deficiency. N Engl J Med. 357:266–281. 2007.PubMed/NCBI View Article : Google Scholar

14 

Heaney RP: Vitamin D in health and disease. Clin J Am Soc Nephrol. 3:1535–1541. 2008.PubMed/NCBI View Article : Google Scholar

15 

de la Puente Yagüe M, Collado Yurrita L, Ciudad Cabañas MJ and Cuadrado Cenzual MA: Role of vitamin D in athletes and their performance: Current concepts and new trends. Nutrients. 12(579)2020.PubMed/NCBI View Article : Google Scholar

16 

MacLaughlin J and Holick MF: Aging decreases the capacity of human skin to produce vitamin D3. J Clin Invest. 76:1536–1538. 1985.PubMed/NCBI View Article : Google Scholar

17 

Caini S, Boniol M, Tosti G, Magi S, Medri M, Stanganelli I, Palli D, Assedi M, Del Marmol V and Gandini S: Vitamin D and melanoma and non-melanoma skin cancer risk and prognosis: A comprehensive review and meta-analysis. Eur J Cancer. 50:2649–2658. 2014.PubMed/NCBI View Article : Google Scholar

18 

Soares AM, Szejnfeld VL, Enokihara MY, Michalany N and Castro CH: High serum 25-hydroxyvitamin D concentration in patients with a recent diagnosis of non-melanoma skin cancer: A case-control study. Eur J Dermatol. 28:649–653. 2018.PubMed/NCBI View Article : Google Scholar

19 

Lesiak A, Norval M, Wodz-Naskiewicz K, Pawliczak R, Rogowski-Tylman M, Sysa-Jedrzejowska A, Sobjanek M, Wlodarkiewicz A and Narbutt J: An enhanced risk of basal cell carcinoma is associated with particular polymorphisms in the VDR and MTHFR genes. Exp Dermatol. 20:800–804. 2011.PubMed/NCBI View Article : Google Scholar

20 

Brouwer-Brolsma EM, Vaes AMM, van der Zwaluw NL, van Wijngaarden JP, Swart KMA, Ham AC, van Dijk SC, Enneman AW, Sohl E, van Schoor NM, et al: Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study. J Steroid Biochem Mol Biol. 164:168–176. 2016.PubMed/NCBI View Article : Google Scholar

21 

Vishlaghi N and Lisse TS: Exploring vitamin D signalling within skin cancer. Clin Endocrinol (Oxf). 92:273–281. 2020.PubMed/NCBI View Article : Google Scholar

22 

Bijlsma MF and Roelink H: Skin-derived vitamin D3 protects against basal cell carcinoma. J Invest Dermatol. 137:2469–2471. 2017.PubMed/NCBI View Article : Google Scholar

23 

Spiro A and Buttriss JL: Vitamin D: An overview of vitamin D status and intake in Europe. Nutr Bull. 39:322–350. 2014.PubMed/NCBI View Article : Google Scholar

24 

Belbasis L, Stefanaki I, Stratigos AJ and Evangelou E: Non-genetic risk factors for cutaneous melanoma and keratinocyte skin cancers: An umbrella review of meta-analyses. J Dermatol Sci. 84:330–339. 2016.PubMed/NCBI View Article : Google Scholar

25 

Makris K, Sempos C and Cavalier E: The measurement of vitamin D metabolites: Part I-metabolism of vitamin D and the measurement of 25-hydroxyvitamin D. Hormones (Athens). 19:81–96. 2020.PubMed/NCBI View Article : Google Scholar

26 

Itkonen ST, Andersen R, Björk AK, Brugård Konde Å, Eneroth H, Erkkola M, Holvik K, Madar AA, Meyer HE, Tetens I, et al: Vitamin D status and current policies to achieve adequate vitamin D intake in the Nordic countries. Scand J Public Health: Jan 9, 2020 (Epub ahead of print). doi: 10.1177/1403494819896878.

27 

Dimakopoulos I, Magriplis E, Mitsopoulou AV, Karageorgou D, Bakogianni I, Micha R, Michas G, Chourdakis M, Chrousos GP, Roma E, et al: Intake and contribution of food groups to vitamin D intake in a representative sample of adult Greek population. Nutrition. 72(110641)2020.PubMed/NCBI View Article : Google Scholar

28 

Wu S, Powers S, Zhu W and Hannun YA: Substantial contribution of extrinsic risk factors to cancer development. Nature. 529:43–47. 2016.PubMed/NCBI View Article : Google Scholar

29 

Guidance on Cancer Services: Improving outcomes for people with skin tumours including melanoma (update). The management of low-risk basal cell carcinomas in the community: NICE guidance on cancer services update (May 2010). National Collaborating Centre for Cancer, pp57, 2010.

30 

Wu S, Han J, Li WQ, Li T and Qureshi AA: Basal-cell carcinoma incidence and associated risk factors in U.S. women and men. Am J Epidemiol. 178:890–897. 2013.PubMed/NCBI View Article : Google Scholar

31 

Verkouteren JA, Ramdas KHR, Wakkee M and Nijsten T: Epidemiology of basal cell carcinoma: Scholarly review. Br J Dermatol. 177:359–372. 2017.PubMed/NCBI View Article : Google Scholar

32 

Ciążyńska M, Narbutt J, Woźniacka A and Lesiak A: Trends in basal cell carcinoma incidence rates: A 16-year retrospective study of a population in central Poland. Postepy Dermatol Alergol. 35:47–52. 2018.PubMed/NCBI View Article : Google Scholar

33 

Vlǎdescu C, Galan A, Olsavszky V and Scîntee SG: Romanian health system strategic directions for the next decade. Ital J Public Health. 6:21–29. 2009.

34 

Naldi L, DiLandro A, D'Avanzo B and Parazzini F: Host-related and environmental risk factors for cutaneous basal cell carcinoma: Evidence from an Italian case-control study. J Am Acad Dermatol. 42:446–452. 2000.PubMed/NCBI View Article : Google Scholar

35 

Iannacone MR, Wang W, Stockwell HG, O'Rourke K, Giuliano AR, Sondak VK, Messina JL, Roetzheim RG, Cherpelis BS, Fenske NA and Rollison DE: Patterns and timing of sunlight exposure and risk of basal cell and squamous cell carcinomas of the skin - a case-control study. BMC Cancer. 12(417)2012.PubMed/NCBI View Article : Google Scholar

36 

Richmond-Sinclair NM, Pandeya N, Williams GM, Neale RE, van der Pols JC and Green AC: Clinical signs of photodamage are associated with basal cell carcinoma multiplicity and site: A 16-year longitudinal study. Int J cancer. 127:2622–2629. 2010.PubMed/NCBI View Article : Google Scholar

37 

Verkouteren JAC, Pardo LM, Uitterlinden AG and Nijsten T: Non-genetic and genetic predictors of a superficial first basal cell carcinoma. J Eur Acad Dermatol Venereol. 33:533–540. 2019.PubMed/NCBI View Article : Google Scholar

38 

Lovatt TJ, Lear JT, Bastrilles J, Wong C, Griffiths CE, Samarasinghe V, Roebuck J, Ramachandran S, Smith AG, Jones PW, et al: Associations between ultraviolet radiation, basal cell carcinoma site and histology, host characteristics, and rate of development of further tumors. J Am Acad Dermatol. 52:468–473. 2005.PubMed/NCBI View Article : Google Scholar

39 

Husein-Elahmed H, Gutierrez-Salmeron MT, Aneiros-Cachaza J and Naranjo-Sintes R: Basal cell carcinoma arising in outdoor workers versus indoor workers: A retrospective study. Cutis. 99:55–60. 2017.PubMed/NCBI

40 

Surdu S, Fitzgerald EF, Bloom MS, Boscoe FP, Carpenter DO, Haase RF, Gurzau E, Rudnai P, Koppova K, Févotte J, et al: Occupational exposure to ultraviolet radiation and risk of non-melanoma skin cancer in a multinational European study. PLoS One. 8(e62359)2013.PubMed/NCBI View Article : Google Scholar

41 

Chesnut C and Kim J: Is there truly no benefit with sunscreen use and Basal cell carcinoma? A critical review of the literature and the application of new sunscreen labeling rules to real-world sunscreen practices. J Skin Cancer. 2012(480985)2012.PubMed/NCBI View Article : Google Scholar

42 

Perugini P, Bonetti M, Cozzi AC and Colombo GL: Topical sunscreen application preventing skin cancer: Systematic review. Cosmetics. 6(42)2019.

43 

Savoye I, Olsen CM, Whiteman DC, Bijon A, Wald L, Dartois L, Clavel-Chapelon F, Boutron-Ruault MC and Kvaskoff M: Patterns of ultraviolet radiation exposure and skin cancer risk: The E3N-sunexp study. J Epidemiol. 28:27–33. 2018.PubMed/NCBI View Article : Google Scholar

44 

van Deventer L, Kannenberg SMH and du Toit J: Vitamin D status in adult patients with nonmelanoma skin cancer in Cape Town, South Africa: A cross-sectional study. Int J Dermatol. 57:922–927. 2018.PubMed/NCBI View Article : Google Scholar

45 

Manios Y, Moschonis G, Lambrinou CP, Tsoutsoulopoulou K, Binou P, Karachaliou A, Breidenassel C, Gonzalez-Gross M, Kiely M and Cashman KD: A systematic review of vitamin D status in southern European countries. Eur J Nutr. 57:2001–2036. 2018.PubMed/NCBI View Article : Google Scholar

46 

Saad RK, Akiki VC, Rahme M, Ajjour S, Assaad M and El-Hajj Fuleihan GA: Time trends and predictors of hypovitaminosis D across the life course: 2009-2016. Metabolism. 105(154138)2020.PubMed/NCBI View Article : Google Scholar

47 

Ince B, Yildirim MEC and Dadaci M: Assessing the effect of vitamin D replacement on basal cell carcinoma occurrence and recurrence rates in patients with vitamin D deficiency. Horm Cancer. 10:145–149. 2019.PubMed/NCBI View Article : Google Scholar

48 

Webb AR, Kline L and Holick MF: Influence of season and latitude on the cutaneous synthesis of vitamin D3: Exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin. J Clin Endocrinol Metab. 67:373–378. 1988.PubMed/NCBI View Article : Google Scholar

49 

Leary PF, Zamfirova I, Au J and McCracken WH: Effect of latitude on vitamin D levels. J Am Osteopath Assoc. 117:433–439. 2017.PubMed/NCBI View Article : Google Scholar

50 

Niculescu DA, Capatina CAM, Dusceac R, Caragheorgheopol A, Ghemigian A and Poiana C: Seasonal variation of serum vitamin D levels in Romania. Arch Osteoporos. 12(113)2017.PubMed/NCBI View Article : Google Scholar

51 

Chirita-Emandi A, Socolov D, Haivas C, Calapiș A, Gheorghiu C and Puiu M: Vitamin D status: A different story in the very young versus the very old Romanian patients. PLoS One. 10(e0128010)2015.PubMed/NCBI View Article : Google Scholar

52 

Eide MJ, Johnson DA, Jacobsen GR, Krajenta RJ, Rao DS, Lim HW and Johnson CC: Vitamin D and nonmelanoma skin cancer in a health maintenance organization cohort. Arch Dermatol. 147:1379–1384. 2011.PubMed/NCBI View Article : Google Scholar

53 

Liang G, Nan H, Qureshi AA and Han J: Pre-diagnostic plasma 25-hydroxyvitamin D levels and risk of non-melanoma skin cancer in women. PLoS One. 7(e35211)2012.PubMed/NCBI View Article : Google Scholar

54 

Asgari MM, Tang J, Warton ME, Chren MM, Quesenberry CP Jr, Bikle D, Horst RL, Orentreich N, Vogelman JH and Friedman GD: Association of prediagnostic serum vitamin D levels with the development of basal cell carcinoma. J Invest Dermatol. 130:1438–1443. 2010.PubMed/NCBI View Article : Google Scholar

55 

Tang JY, Parimi N, Wu A, Boscardin WJ, Shikany JM, Chren MM, Cummings SR, Epstein EH and Bauer DC: Osteoporotic Fractures in Men (MrOS) Study Group. Inverse association between serum 25(OH) vitamin D levels and non-melanoma skin cancer in elderly men. Cancer Causes Control. 21:387–391. 2010.PubMed/NCBI View Article : Google Scholar

56 

Young AR, Narbutt J, Harrison GI, Lawrence KP, Bell M, O'Connor C, Olsen P, Grys K, Baczynska KA, Rogowski-Tylman M, et al: Optimal sunscreen use, during a sun holiday with a very high ultraviolet index, allows vitamin D synthesis without sunburn. Br J Dermatol. 181:1052–1062. 2019.PubMed/NCBI View Article : Google Scholar

57 

Whiteman DC, Neale RE, Aitken J, Gordon L, Green AC, Janda M, Olsen CM and Soyer HP: Sunscreen Summit Policy Group. When to apply sunscreen: A consensus statement for Australia and New Zealand. Aust N Z J Public Health. 43:171–175. 2019.PubMed/NCBI View Article : Google Scholar

58 

Koch S, Pettigrew S, Minto C, Slevin T, Strickland M, Lin C and Jalleh G: Trends in sun-protection behaviour in Australian adults 2007-2012. Australas J Dermatol. 58:111–116. 2017.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Vornicescu C, Ungureanu L, Șenilă SC, Vesa ȘC, Cosgarea R, Baican CI and Mihu MC: Assessment of sun‑related behavior and serum vitamin&nbsp;D in basal cell carcinoma: Preliminary results. Exp Ther Med 20: 187, 2020.
APA
Vornicescu, C., Ungureanu, L., Șenilă, S.C., Vesa, Ș.C., Cosgarea, R., Baican, C.I., & Mihu, M.C. (2020). Assessment of sun‑related behavior and serum vitamin&nbsp;D in basal cell carcinoma: Preliminary results. Experimental and Therapeutic Medicine, 20, 187. https://doi.org/10.3892/etm.2020.9317
MLA
Vornicescu, C., Ungureanu, L., Șenilă, S. C., Vesa, Ș. C., Cosgarea, R., Baican, C. I., Mihu, M. C."Assessment of sun‑related behavior and serum vitamin&nbsp;D in basal cell carcinoma: Preliminary results". Experimental and Therapeutic Medicine 20.6 (2020): 187.
Chicago
Vornicescu, C., Ungureanu, L., Șenilă, S. C., Vesa, Ș. C., Cosgarea, R., Baican, C. I., Mihu, M. C."Assessment of sun‑related behavior and serum vitamin&nbsp;D in basal cell carcinoma: Preliminary results". Experimental and Therapeutic Medicine 20, no. 6 (2020): 187. https://doi.org/10.3892/etm.2020.9317
Copy and paste a formatted citation
x
Spandidos Publications style
Vornicescu C, Ungureanu L, Șenilă SC, Vesa ȘC, Cosgarea R, Baican CI and Mihu MC: Assessment of sun‑related behavior and serum vitamin&nbsp;D in basal cell carcinoma: Preliminary results. Exp Ther Med 20: 187, 2020.
APA
Vornicescu, C., Ungureanu, L., Șenilă, S.C., Vesa, Ș.C., Cosgarea, R., Baican, C.I., & Mihu, M.C. (2020). Assessment of sun‑related behavior and serum vitamin&nbsp;D in basal cell carcinoma: Preliminary results. Experimental and Therapeutic Medicine, 20, 187. https://doi.org/10.3892/etm.2020.9317
MLA
Vornicescu, C., Ungureanu, L., Șenilă, S. C., Vesa, Ș. C., Cosgarea, R., Baican, C. I., Mihu, M. C."Assessment of sun‑related behavior and serum vitamin&nbsp;D in basal cell carcinoma: Preliminary results". Experimental and Therapeutic Medicine 20.6 (2020): 187.
Chicago
Vornicescu, C., Ungureanu, L., Șenilă, S. C., Vesa, Ș. C., Cosgarea, R., Baican, C. I., Mihu, M. C."Assessment of sun‑related behavior and serum vitamin&nbsp;D in basal cell carcinoma: Preliminary results". Experimental and Therapeutic Medicine 20, no. 6 (2020): 187. https://doi.org/10.3892/etm.2020.9317
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team