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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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December-2020 Volume 20 Issue 6

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Impact Factor: 2.3

Review Open Access

The foundation of the Institute of Paediatric Virology on the island of Euboea, Greece (Review)

Ioannis N. Mammas, Anne Greenough, Maria Theodoridou, Demetrios A. Spandidos
Article Number: 302
Published online on: 30 October 2020

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Comment Open Access

[Comment] Paediatric virology and medical terminology

Ioannis N. Mammas, Simon B. Drysdale, Maria Theodoridou, Anne Greenough, Demetrios A. Spandidos
Article Number: 301
Published online on: 30 October 2020

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Comment Open Access

[Comment] Viruses, vaccinations and RSV: Exploring terminology in paediatric virology

Ioannis N. Mammas, Simon B. Drysdale, Maria Theodoridou, Anne Greenough, Demetrios A. Spandidos
Article Number: 300
Published online on: 30 October 2020

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Editorial Open Access

[Editorial] HPV infection in children, astrometry and the end of a Greek legend

Ioannis N. Mammas, Chryssie Koutsaftiki, Alexia Papatheodoropoulou, Demetrios A. Spandidos
Article Number: 299
Published online on: 30 October 2020

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Editorial Open Access

[Editorial] Creating the Institute of Paediatric Virology: In honor of Professor Anne Greenough

Ioannis N. Mammas
Article Number: 298
Published online on: 30 October 2020

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Opinion Open Access

[Opinion] Creating the ‘George N. Papanicolaou Medal’ by the Academy of Athens: An interview with Professor of Sculpture Theodoros Papagiannis (Athens School of Fine Arts, Athens, Greece)

Ioannis N. Mammas, Chryssie Koutsaftiki, Alexia Papatheodoropoulou, Demetrios A. Spandidos
Article Number: 297
Published online on: 30 October 2020

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Opinion Open Access

[Opinion] COVID‑19 and paediatric challenges: An interview with Professor of Paediatrics Vana Papaevangelou (University of Athens School of Medicine)

Ioannis N. Mammas, Maria Theodoridou, Demetrios A. Spandidos
Article Number: 296
Published online on: 30 October 2020

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Opinion Open Access

[Opinion] The challenge of paediatric epilepsy nursing: An interview with Mrs. Jenny O'Brien, paediatric epilepsy nursing specialist at the Wirral University Teaching Hospital, UK

Ioannis N. Mammas, Demetrios A. Spandidos
Article Number: 295
Published online on: 30 October 2020

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Opinion Open Access

[Opinion] Retinopathy of prematurity and neonatal gut microbiome: An interview with Professor Dimitra Skondra, Associate Professor of Ophthalmology and Vitreoretinal Surgeon at The University of Chicago (USA)

Ioannis N. Mammas, Demetrios A. Spandidos
Article Number: 294
Published online on: 30 October 2020

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Review Open Access

Update on COVID‑19: A teleconference with the Paediatric Virology Study Group (Review)

Vasilios Tzilas, Demosthenes Bouros
Article Number: 293
Published online on: 30 October 2020

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Comment Open Access

[Comment] COVID-19 threat and the 1918 Spanish flu outbreak: The following day

Ioannis N. Mammas, Maria Theodoridou, Demetrios A. Spandidos
Article Number: 292
Published online on: 30 October 2020

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Comment Open Access

[Comment] COVID‑19 threat and frontline paediatric care professionals

Chryssie Koutsaftiki, Alexia Papatheodoropoulou, Georgia Papaioannou, Paraskevi Korovessi, Ioannis N. Mammas, Maria Theodoridou, Demetrios A. Spandidos
Article Number: 291
Published online on: 30 October 2020

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Review Open Access

Training in paediatric virology in the UK: A brief overview (Review)

Simon B. Drysdale, Aisleen M. Bennett, Anne Greenough
Article Number: 290
Published online on: 30 October 2020

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Editorial Open Access

[Editorial] An idea, an aim, an institute devoted to medical education on paediatric virology

Ioannis N. Mammas
Article Number: 289
Published online on: 30 October 2020

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Editorial Open Access

[Editorial] Paediatric infectious diseases in Greece: Insights from a tertiary reference unit and perspectives for the future

Maria Theodoridou
Article Number: 288
Published online on: 30 October 2020

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Editorial Open Access

[Editorial] The newly founded Institute of Paediatric Virology and the 1918 flu outbreak: From mnemosyne to scientific truth

Demetrios A. Spandidos
Article Number: 287
Published online on: 30 October 2020

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Article Open Access

Efficacy of atovaquone on EpCAM+CD44+ HCT‑116 human colon cancer stem cells under hypoxia

Changhao Fu, Xu Xiao, Hao Xu, Weifei Lu, Yi Wang
Article Number: 286
Published online on: 29 October 2020

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Review Open Access

Engineered Akkermansia muciniphila: A promising agent against diseases (Review)

Yixuan Zou, Tingtao Chen
Article Number: 285
Published online on: 29 October 2020

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Article Open Access

Small molecule CDS-3078 induces G2/M phase arrest and mitochondria-mediated apoptosis in HeLa cells Corrigendum in /10.3892/etm.2025.12938

Yuanxin Zhang, Pengcheng Li, Jiamin Rong, Yakun Ge, Chenming Hu, Xu Bai, Wei Shi
Article Number: 284
Published online on: 29 October 2020

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Article Open Access

Low‑dose X‑ray irradiation induces morphological changes and cytoskeleton reorganization in osteoblasts

Qun Huang, Zhiping Zhou, Fei Yan, Qirong Dong, Liming Wang, Weiping Sha, Qin Xu, Xianwei Zhu, Lei Zhao
Article Number: 283
Published online on: 29 October 2020

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Correction Open Access

[Corrigendum] miR‑26b inhibits isoproterenol‑induced cardiac fibrosis via the Keap1/Nrf2 signaling pathway

Shaohua Xiang, Jing Li, Zhengfu Zhang
Article Number: 282
Published online on: 29 October 2020

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Article Open Access

Analysis on the pathogenic fungi in patients with superficial mycosis in the Northeastern China during 10 years

Xiufen Wang, Changrui Ding, Yulong Xu, Haomiao Yu, Songdi Zhang, Cuiyun Yang
Article Number: 281
Published online on: 27 October 2020

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Article

Quercetin modulates AMPK/SIRT1/NF‑κB signaling to inhibit inflammatory/oxidative stress responses in diabetic high fat diet‑induced atherosclerosis in the rat carotid artery

Fengwei Zhang, Jia Feng, Jingyu Zhang, Xin Kang, Dun Qian
Article Number: 280
Published online on: 27 October 2020

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Article Open Access

Autogenous bone particles combined with platelet‑rich plasma can stimulate bone regeneration in rabbits

Huanxin Xie, Lei Cao, Linlin Ye, Jubao Du, Guixiang Shan, Jie Hu, Chunjing Jiang, Weiqun Song
Article Number: 279
Published online on: 27 October 2020

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Article Open Access

Early radiologic and bronchoscopic changes after bronchial thermoplasty in patients with severe asthma

Minzhi Qiu, Shushan Wei, Zhengdao Lai, Peikai Huang, Zhiqiang Wang, Changhao Zhong, Yu Chen, Xiaoxian Zhang, Xiaofeng Lin, Qingsi Zeng, Kian Fan Chung, Qingling Zhang, Jiaxing Xie, Shiyue Li
Article Number: 278
Published online on: 27 October 2020

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Article

Efficacy and prognosis of surgical treatment in ARMM and its effects on immune and inflammatory profiles

Mei Huan, Wei Tian, Zhixia Zhang
Article Number: 277
Published online on: 27 October 2020

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Article Open Access

Effect of magnesium sulfate combined with labetalol on serum sFlt‑1/PlGF ratio in patients with early‑onset severe pre‑eclampsia

Ying Wang, Jing Bao, Min Peng
Article Number: 276
Published online on: 27 October 2020

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Article

Effect of dexmedetomidine combined with etomidate on IL‑17A and S‑100β expression levels in rats with postoperative cognitive dysfunction

Xiaoli Yu, Yunfang Xie
Article Number: 275
Published online on: 27 October 2020

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Article

Efficacy of neurointervention combined with intravenous thrombolysis in the treatment of ischemic cerebrovascular disease and its influence on neurological function and prognosis of patients

Shixing Li, Xuelei Lou, Zukuan Chang, Chaoheng Shi, Huilin Lu, Jiankui Han
Article Number: 274
Published online on: 27 October 2020

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Article Open Access

Effect of chronic obstructive pulmonary disease combined with ventilator‑associated pneumonia on patient outcomes: A systematic review and meta‑analysis

Mingyuan Yin, Meirong Liu
Article Number: 273
Published online on: 27 October 2020

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Review Open Access

Lactoferrin for the treatment of COVID‑19 (Review)

Yidan Wang, Puxiu Wang, Haoran Wang, Yifan Luo, Long Wan, Mingyan Jiang, Yang Chu
Article Number: 272
Published online on: 27 October 2020

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Article Open Access

Beneficial role of microRNA‑328‑3p in fracture healing by enhancing osteoblastic viability through the PTEN/PI3K/AKT pathway

Wei Xie, Zhuqing Wang, Yanbo Zhang, Zhenpeng Zhang
Article Number: 271
Published online on: 27 October 2020

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Article

Puerarin protects vascular smooth muscle cells from oxidized low‑density lipoprotein‑induced reductions in viability via inhibition of the p38 MAPK and JNK signaling pathways

Yanwu Hu, Haitao Li, Ruili Li, Zijing Wu, Wenxin Yang, Wei Qu
Article Number: 270
Published online on: 27 October 2020

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Article Open Access

Dimethyl fumarate protects nucleus pulposus cells from inflammation and oxidative stress and delays the intervertebral disc degeneration

Hainian Zhu, Gang Chen, Yuhua Wang, Xuchen Lin, Jingyuan Zhou, Zengshun Wang, Nanangxiu Suo
Article Number: 269
Published online on: 27 October 2020

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Review Open Access

Endoplasmic reticulum stress serves an important role in cardiac ischemia/reperfusion injury (Review)

Yongxue Ruan, Jingjing Zeng, Qike Jin, Maoping Chu, Kangting Ji, Zhongyu Wang, Lei Li
Article Number: 268
Published online on: 27 October 2020

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Article Open Access

Effect of sericin on the p38MAPK signaling pathway and NLRP3 inflammasome in the kidney of type 2 diabetic rats

Donghui Liu, Cheng Chen, Dandan Wang, Zhihong Chen, Chengjun Song
Article Number: 267
Published online on: 27 October 2020

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Review Open Access

Mitochondrial dysfunction and pancreatic islet β‑cell failure (Review)

Wenxin Sha, Fei Hu, Shizhong Bu
Article Number: 266
Published online on: 27 October 2020

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Article Open Access

Diagnostic accuracy of transvaginal ultrasound examination for assigning a specific diagnosis to adnexal masses: A meta‑analysis

Xiya Zhang, Xuan Meng, Ting Dou, Hui Sun
Article Number: 265
Published online on: 27 October 2020

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Case Report

Missed diagnosis and delayed treatment of acromegaly in a patient with severe diabetes: A case report

Kota Nishihama, Yutaka Yano, Taro Yasuma, Esteban C. Gabazza
Article Number: 264
Published online on: 27 October 2020

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Article Open Access

Genotype‑phenotype analysis in Mowat‑Wilson syndrome associated with two novel and two recurrent ZEB2 variants

Dongfang Zou, Lin Wang, Feiqiu Wen, Hongdou Xiao, Jing Duan, Tongda Zhang, Zhenzhen Yin, Qiwen Dong, Jian Guo, Jianxiang Liao
Article Number: 263
Published online on: 27 October 2020

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Article Open Access

Combined effects on leukemia cell growth by targeting sphingosine kinase 1 and sirtuin 1 signaling

Yuxiang Li, Yuxia Gao, Bing Liang, Wenbo Nie, Lijing Zhao, Lisheng Wang
Article Number: 262
Published online on: 27 October 2020

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Article Open Access

Long non‑coding RNA ATB is associated with metastases and promotes cell invasion in colorectal cancer via sponging miR‑141‑3p Corrigendum in /10.3892/etm.2022.11163

Xianming Liu, Cunchuan Wang
Article Number: 261
Published online on: 27 October 2020

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Article Open Access

Comprehensive evaluation of differential long non‑coding RNA and gene expression in patients with cartilaginous endplate degeneration of cervical vertebra

Jinghong Yuan, Jingyu Jia, Tianlong Wu, Xijuan Liu, Shen Hu, Jian Zhang, Rui Ding, Chongzhi Pang, Xigao Cheng
Article Number: 260
Published online on: 27 October 2020

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Article Open Access

Impact of prior endovascular interventions on outcomes of lower limb bypass surgery: A systematic review and meta‑analysis

Hai Xin, Yongxin Li, Xiaomei Guan, Yuewei Wang, Junjun Liu, Xukui Liu, Jinping Wang, Liyuan Niu, Jun Li
Article Number: 259
Published online on: 27 October 2020

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Article

Influence of cataract surgery on macular vascular density in patients with myopia using optical coherence tomography angiography

Tingting Li, Awoke Guadie, Le Feng, Jianwu Fan, Ziyuan Jiang, Fang Liu
Article Number: 258
Published online on: 27 October 2020

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Article Open Access

Human umbilical cord mesenchymal stem cells ameliorate skin fibrosis development in a mouse model of bleomycin‑induced systemic sclerosis

Yuan Yang, Shuai Zhu, Yanhong Li, Qian Lu, Qiuyi Zhang, Linchong Su, Qiuping Zhang, Yi Zhao, Yubin Luo, Yi Liu
Article Number: 257
Published online on: 27 October 2020

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Article

Radiological‑prognostic correlation of diffusion tensor imaging in a mild traumatic brain injury model

Yuting Zhang, Lusheng Li, Ling He
Article Number: 256
Published online on: 27 October 2020

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Article Open Access

MicroRNA‑208a‑3p promotes osteosarcoma progression via targeting PTEN

Yutuo Fu, Yan Wang, Ke Bi, Lei Yang, Yi Sun, Boyuan Li, Zhenzhong Liu, Fulin Zhang, Yuan Li, Chao Feng, Zhenggang Bi
Article Number: 255
Published online on: 23 October 2020

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Article Open Access

Expression profiles of the Wnt/β‑catenin signaling‑related extracellular antagonists during proliferation and differentiation in human osteoblast‑like cells

Alma Y. Parra‑Torres, Juana Enríquez, Rogelio F. Jiménez‑Ortega, Nelly Patiño, Manuel De Jesús Castillejos‑López, Luz M. Torres‑Espíndola, Eric G. Ramírez‑Salazar, Rafael Velázquez‑Cruz
Article Number: 254
Published online on: 23 October 2020

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Article Open Access

Tear proteomics of orbital decompression for disfiguring exophthalmos in inactive thyroid‑associated ophthalmopathy

Lihong Jiang, Ao Rong, Ruili Wei, Jiale Diao, Hui Ding, Wei Wang
Article Number: 253
Published online on: 23 October 2020

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Article Open Access

Clinical outcomes of MED and iLESSYS® Delta for the treatment of lumbar central spinal stenosis and lateral recess stenosis: A comparison study

Boyu Wu, Chengjie Xiong, Linying Tan, Dongdong Zhao, Feng Xu, Hui Kang
Article Number: 252
Published online on: 23 October 2020

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Article Open Access

Biochanin A alleviates gingival inflammation and alveolar bone loss in rats with experimental periodontitis

Shengdan Zhang, Yulong Niu, Zhuo Yang, Yuwei Zhang, Qiang Guo, Yi Yang, Xuedong Zhou, Yi Ding, Chengcheng Liu
Article Number: 251
Published online on: 23 October 2020

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Article Open Access

Effect of dexmedetomidine on hemodynamic changes and inflammatory responses in patients undergoing off‑pump coronary‑artery bypass grafting

Wenqian Zhai, Lieming Yang, Peng Sun, Yunfei Li, Jiange Han, Guolin Wang
Article Number: 250
Published online on: 23 October 2020

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Article Open Access

Sophocarpine attenuates septic liver injury through suppression of the NLRP3 inflammasome via autophagy‑mediated degradation

Nianguo Hou, Xiaofeng Dai, Wenqing Lu, Hongguang Yang, Haida Yu, Junchao Liu, Hui Li, Xunjun Shuai, Dengbin Ai
Article Number: 249
Published online on: 23 October 2020

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Article Open Access

Application of interventional embolization in the treatment of iatrogenic pseudoaneurysms

Hao Xu, Cong Jing, Jie Zhou, Xuli Min, Jing Zhao, Lin Yang, Yongjun Ren
Article Number: 248
Published online on: 22 October 2020

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Article Open Access

MicroRNA‑122 regulates docetaxel resistance of prostate cancer cells by regulating PKM2

Zhirong Zhu, Guiliang Tang, Jiajun Yan
Article Number: 247
Published online on: 22 October 2020

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Article

Long non‑coding RNA RPSAP52 upregulates Timp3 by serving as the endogenous sponge of microRNA‑365 in diabetic retinopathy

Tongtong Niu, Yan An, Tingting Lv, Dongning Liu
Article Number: 246
Published online on: 22 October 2020

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Article Open Access

Comparison of regulatory networks of E74‑like factor 1 and cold‑shock domain‑containing E1 in breast cancer cell lines using ChIP datasets

Haibo Duan, Huafang He, Qian Hu, Yingxin Lin, Shuo Cao, Xiaoshan Lan, Litao Li, Danmei Pang
Article Number: 245
Published online on: 22 October 2020

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Article Open Access

Selection and validation of optimal endogenous reference genes for analysis of quantitative PCR in four tissues pathologically associated with Kidney‑yang deficiency syndrome following influenza A infection

Yepei Fu, Jia Yang, Shanshan Fan, Shaozhe Zhao, Ruikun Du, Syed Muhammad Ali Shah, Muhammad Akram, Rong Rong, Yong Yang
Article Number: 244
Published online on: 22 October 2020

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Article

Associations of BRAF V600E, clinical pathology and imaging factors with the recurrence rate of papillary thyroid microcarcinoma

Kun Huang, Ningning Gao, Donglin Bian, Qixi Zhai, Puxu Yang, Yunfei Zhang
Article Number: 243
Published online on: 22 October 2020

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Article

MBD2 and EZH2 regulate the expression of SFRP1 without affecting its methylation status in a colorectal cancer cell line

Jun Yu, Yang Xie, Yuting Liu, Feng Wang, Mengying Li, Jian Qi
Article Number: 242
Published online on: 22 October 2020

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Article Open Access

Lack of sphingomyelin synthase 2 reduces cerebral ischemia/reperfusion injury by inhibiting microglial inflammation in mice

Yu Yang, Fengxian Hu, Guifeng Yang, Qingmei Meng
Article Number: 241
Published online on: 22 October 2020

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Article Open Access

Paroxetine combined with fluorouracil plays a therapeutic role in mouse models of colorectal cancer with depression through inhibiting IL‑22 expression to regulate the MAPK signaling pathway

Huijie Zhang, Meixv Chen, Ying Liu, Xiaomei Dong, Chan Zhang, Han Jiang, Xue Chen
Article Number: 240
Published online on: 22 October 2020

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Article Open Access

MicroRNA‑342‑5p activates the Akt signaling pathway by downregulating PIK3R1 to modify the proliferation and differentiation of vascular smooth muscle cells

Sisi Bi, Qingling Peng, Wenxue Liu, Chenglong Zhang, Zhaoya Liu
Article Number: 239
Published online on: 22 October 2020

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Article Open Access

Ginsenoside Rg3 alleviates inflammation in a rat model of myocardial infarction via the SIRT1/NF-κB pathway

Chenchen Tu, Baoyan Wan, Yong Zeng
Article Number: 238
Published online on: 22 October 2020

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Article

Direct oral anticoagulant treatment of deep vein thrombosis reduces IL‑6 expression in peripheral mono‑nuclear blood cells

Saverio Candido, Giovanni Lumera, Giuliana Barcellona, Davide Vetri, Elda Tumino, Ingrid Platania, Evelise Frazzetto, Graziella Privitera, Carmela Incognito, Agostino Gaudio, Salvatore Santo Signorelli
Article Number: 237
Published online on: 21 October 2020

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MicroRNA‑210 improves perfusion recovery following hindlimb ischemia via suppressing reactive oxygen species

Jinfeng Zhang, Guotao Rao, Junying Qiu, Ronghua He, Qiongtao Wang
Article Number: 236
Published online on: 16 October 2020

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Article

Rapid method for direct identification of positive blood cultures by MALDI‑TOF MS

Yueling Wang, Yan Jin, Yuanyuan Bai, Zhen Song, Wenjun Chu, Mengqi Zhao, Yingying Hao, Zhiming Lu
Article Number: 235
Published online on: 16 October 2020

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Review

Research and prospect of peptides for use in obesity treatment (Review)

Yao Gao, Xuewen Yuan, Ziyang Zhu, Dandan Wang, Qianqi Liu, Wei Gu
Article Number: 234
Published online on: 16 October 2020

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Clinical study on repair of metacarpal bone defects using titanium alloy implantation and autologous bone grafting

Yue Zheng, Jinliang Wang, Bolun Chang, Li Zhang
Article Number: 233
Published online on: 16 October 2020

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Predictive value of serum VEGF, IL‑1 and TNF‑α in the treatment of thromboangiitis obliterans by revascularization

Zheng-Fei Li, Xiao-Jun Shu, Wen-Hui Wang, Sheng-Ye Liu, Lei Dang, Yan-Qiang Shi, Yan-Wen Bai
Article Number: 232
Published online on: 16 October 2020

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HMGB‑1/RAGE signaling inhibition by dioscin attenuates hippocampal neuron damage induced by oxygen‑glucose deprivation/reperfusion

Aijun Liu, Wenqian Zhang, Shuwei Wang, Yuan Wang, Jun Hong
Article Number: 231
Published online on: 15 October 2020

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lncRNA uc.48+ regulates immune and inflammatory reactions mediated by the P2X7 receptor in type 2 diabetic mice

Hong Wu, Mei Jiang, Qiang Liu, Fang Wen, Yijun Nie
Article Number: 230
Published online on: 15 October 2020

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Ginseng polysaccharide inhibits MDA‑MB‑231 cell proliferation by activating the inflammatory response

Haoliang Zhou, Yuxiang Yan, Xianbo Zhang, Ting Zhao, Jiangang Xu, Ruokuo Han
Article Number: 229
Published online on: 15 October 2020

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CD14+ monocytes and CD163+ macrophages correlate with the severity of liver fibrosis in patients with chronic hepatitis C

Su-Xian Zhao, Wen-Cong Li, Na Fu, Ling-Bo Kong, Qing-Shan Zhang, Fang Han, Wei-Guang  Ren, Po Cui, Jing-Hua Du, Bao-Yu Wang, Yu-Guo Zhang, Rong-Qi Wang, Li Kong, Yue-Min Nan
Article Number: 228
Published online on: 15 October 2020

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MicroRNA‑124 regulates cell pyroptosis during cerebral ischemia‑reperfusion injury by regulating STAT3

Hui Sun, Jing-Jing Li, Zi-Ren Feng, Hai-Ying Liu, Ai-Guo Meng
Article Number: 227
Published online on: 15 October 2020

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Article

Baicalin promotes extracellular matrix synthesis in chondrocytes via the activation of hypoxia‑inducible factor‑1α

Pengzhen Wang, Pingping Zhu, Ruijia Liu, Qingqi Meng, Siming Li
Article Number: 226
Published online on: 15 October 2020

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lncRNA ZEB1‑AS1 is downregulated in diabetic lung and regulates lung cell apoptosis

Lizhi Gu, Hong Sun, Zhuan Yan
Article Number: 225
Published online on: 15 October 2020

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Expression of CD27 and CD28 on γδ T cells from the peripheral blood of patients with allergic rhinitis

Qiong Wang, Qun Sun, Qiguo Chen, Hao Li, Ding Liu
Article Number: 224
Published online on: 15 October 2020

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Review Open Access

COVID‑19 in China: From epidemiology to treatment (Review)

Hongtao Chen, Shipin Wu, Xiaoyong Zhang
Article Number: 223
Published online on: 15 October 2020

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Article

miR‑15b, a diagnostic biomarker and therapeutic target, inhibits oesophageal cancer progression by regulating the PI3K/AKT signalling pathway

Jie Liu, Haiyan Xu, Nan Wang, Mingyan Sun
Article Number: 222
Published online on: 15 October 2020

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Daphnetin suppresses experimental abdominal aortic aneurysms in mice via inhibition of aortic mural inflammation

Shiyun Xie, Li Ma, Hongliang Guan, Su Guan, Lijuan Wen, Chanchan Han
Article Number: 221
Published online on: 15 October 2020

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Efficacy and safety of interferon on neonates with respiratory syncytial virus pneumonia

Lingyun He, Lu Yang, Hua Zhang, Qian Luo
Article Number: 220
Published online on: 15 October 2020

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Article

Combined use of thyroid stimulating hormone plus free thyroxine levels and gestational age at birth for the prediction of neonatal hypothyroidism and associated risk factors

Junqi Li, Jing Cheng, Qiuyue Li
Article Number: 219
Published online on: 15 October 2020

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Case Report Open Access

Cumulative visual impact of two coagulability disorders: A case report

Horia T. Stanca, Bogdana Tăbăcaru, Florian Baltă, Monica Mălăescu, Simona Stanca, Mihnea Munteanu, Diana-Maria Dărăbuș, Cosmin Roșca, Adrian Cosmin Teodoru
Article Number: 218
Published online on: 15 October 2020

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Review

Vaccination in multiple sclerosis ‑ Challenging practices (Review)

Carmen Adella Sirbu, Anca Alexandra Florea, Minerva Claudia Ghinescu, Any Docu‑Axelerad, Anca Maria Sirbu, Ovidiu Gabriel Bratu, Florentina Ionita Radu
Article Number: 217
Published online on: 15 October 2020

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A new perspective towards failure of gamma nail systems

Şerban Dragosloveanu, Christiana D.M. Dragosloveanu, Horia T. Stanca, Dragoş C. Cotor, Călin I. Dragosloveanu, Cristian I. Stoica
Article Number: 216
Published online on: 15 October 2020

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Article

Tricalcium phosphate and hydroxyapatite treatment for benign cavitary bone lesions: A prospective clinical trial

Şerban Dragosloveanu, Christiana D.Μ. Dragosloveanu, Horia T. Stanca, Dragoş C. Cotor, Adrian C. Andrei, Călin I. Dragosloveanu, Cristian I. Stoica
Article Number: 215
Published online on: 15 October 2020

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Endurance of erythrocyte series in chemotherapy

Sorin Săftescu, Dorel Popovici, Cristina Oprean, Alina Negru, Adina Croitoru, Mihail Zemba, Ionela Yasar, Maria Preda, Șerban Negru
Article Number: 214
Published online on: 15 October 2020

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Review

Recent advances in surface‑enhanced Raman spectroscopy based liquid biopsy for colorectal cancer (Review)

Lucretia Avram, Andrei Stefancu, Dana Crisan, Nicolae Leopold, Valer Donca, Elena Buzdugan, Rares Craciun, David Andras, Ioan Coman
Article Number: 213
Published online on: 14 October 2020

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Mutations of filament‑aggregating protein gene in Romanian children diagnosed with atopic dermatitis

Anca E. Chiriac, Roxana Popescu, Lăcrămioara Butnariu, Alina Murgu, Liliana Foia, Doina Azoicai
Article Number: 212
Published online on: 15 October 2020

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Review Open Access

Mental health and immunity (Review)

Cristian Vasile
Article Number: 211
Published online on: 14 October 2020

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Article

Predictive factors in early onset schizophrenia

Magdalena Budisteanu, Emanuela Andrei, Florentina Linca, Diana Stefania Hulea, Alexandra Catalina Velicu, Ilinca Mihailescu, Sorin Riga, Aurora Arghir, Sorina Mihaela Papuc, Carmen Adella Sirbu, Marian Mitrica, Any Docu‑Axelerad, Minerva Claudia Ghinescu, Iuliana Dobrescu, Florina Rad
Article Number: 210
Published online on: 14 October 2020

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Effect of Lactobacillus plantarum ACTT 8014 on 5‑fluorouracil induced intestinal mucositis in Wistar rats

Lidia Ciobanu, Cristian Tefas, Diana Maria Oancea, Cristian Berce, Dan Vodnar, Alexandru Mester, Sorina Onica, Corina Toma, Marian Taulescu
Article Number: 209
Published online on: 14 October 2020

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Case Report Open Access

Subretinal alteplase injections in massive subretinal hemorrhage due to age‑related macular degeneration: A case report series

Radu Ochinciuc, Florian Balta, Daniel Constantin Branisteanu, Marian Burcea, Mihail Zemba, Uliana Ochinciuc, Ramona Barac
Article Number: 208
Published online on: 14 October 2020

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Article

Current practices in haemophilic patients undergoing orthopedic surgery ‑ a systematic review

Oana Viola Badulescu, Nina Filip, Paul Dan Sirbu, Iris Bararu‑Bojan, Maria Vladeanu, Andrei Bojan, Manuela Ciocoiu
Article Number: 207
Published online on: 14 October 2020

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Article

Importance of food in the control of inflammation in atopic dermatitis

Maria Rotaru, Gabriela Mariana Iancu, Irina Mihaela Matran
Article Number: 206
Published online on: 14 October 2020

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Article

Reducing upper digestive bleeding risk in patients treated with direct oral anticoagulants and concomitant infection with Helicobacter pylori

Andra-Iulia Suceveanu, Adrian-Paul Suceveanu, Irinel Parepa, Laura  Mazilu, Anca Pantea‑Stoian, Camelia Diaconu, Florin Botea, Vlad Herlea, Sergiu  Ioan Micu, Liliana Ana Tuta, Daniel Ovidiu Costea, Felix Voinea
Article Number: 205
Published online on: 14 October 2020

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Review Open Access

Intraocular pressure changes during and after silicone oil endotamponade (Review)

Daniel Constantin Branisteanu, Andreea Dana Moraru, Minela Aida Maranduca, Daciana Elena Branisteanu, Gabriela Stoleriu, Catalina Ioana Branisteanu, Florian Balta
Article Number: 204
Published online on: 14 October 2020

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Follicle‑stimulating hormone receptor gene polymorphisms of ovarian reserve markers in Romanian population

Adina-Elena Tănase, Dragos Nemescu, Roxana Popescu, Alexandru  Carauleanu, Raluca Anamaria Mogos, Alexandru Luca, Mircea Onofriescu
Article Number: 203
Published online on: 14 October 2020

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Article

Implications of self‑esteem in the quality of life in patients with psoriasis

Ilarie Brihan, Simona Laura Ianoși, Daniel Boda, Angelica Hălmăjan, Mihaela Zdrîncă, László Gyula Fekete
Article Number: 202
Published online on: 14 October 2020

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A qualitative and semiquantitative SEM study of the morphology of the biofilm on root surfaces of human teeth with endodontic‑periodontal lesions

Darian Rusu, Stefan-Ioan Stratul, Horia Calniceanu, Marius Boariu, Alexandru Ogodescu, Stefan Milicescu, Andreea Didilescu, Alexandra Roman, Petra Surlin, Cosmin Locovei, Monica Chiperi, Sorina Solomon, Luminita Nica
Article Number: 201
Published online on: 14 October 2020

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Article

Neuroendocrine syndrome in bronchial carcinoid tumors

Cornel Savu, Alexandru Melinte, Joseph Lula Lukadi, Cristian Mirvald, Carmen Savu, Emil Belu, Camelia Diaconu, Laura Iliescu, Irina Balescu, Ovidiu Stiru, Ovidiu Bratu, Gabriel Gorecki, Nicolae Bacalbasa
Article Number: 200
Published online on: 14 October 2020

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Changes in clinical and microbiological parameters of the periodontium during initial stages of orthodontic movement in patients with treated severe periodontitis: A longitudinal site‑level analysis

Horia Calniceanu, Stefan-Ioan Stratul, Darian Rusu, Alexandru Jianu, Marius Boariu, Luminita Nica, Alexandru Ogodescu, Laurentiu Sima, Sorin Bolintineanu, Andrei Anghel, Stefan Milicescu, Andreea Didilescu, Alexandra Roman, Petra Surlin, Sorina Solomon, Mirona Tudor, Anne Marie Rauten
Article Number: 199
Published online on: 14 October 2020

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Review Open Access

Treatment trends in oral lichen planus and oral lichenoid lesions (Review)

Doina Rotaru, Radu Chisnoiu, Alina Monica Picos, Andrei Picos, Andrea Chisnoiu
Article Number: 198
Published online on: 14 October 2020

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Article

Interactions between leptin and insulin resistance in patients with prediabetes, with and without NAFLD

Simona Bungau, Tapan Behl, Delia Mirela Tit, Florin Banica, Ovidiu G. Bratu, Camelia C. Diaconu, Carmen D. Nistor‑Cseppento, Cristiana Bustea, Raluca A. Corb Aron, Cosmin Mihai Vesa
Article Number: 197
Published online on: 14 October 2020

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Review

Autonomic dysfunctions in multiple sclerosis: Challenges of clinical practice (Review)

Carmen Adella Sirbu, Raluca-Mihaela Mezei, Cristian Falup‑Pecurariu, Ovidiu Gabriel Bratu, Anca Maria Sirbu, Minerva Claudia Ghinescu, Florentina Ionita Radu
Article Number: 196
Published online on: 14 October 2020

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Article

Different clinical significance of ASAP/HGPIN pattern in systematic vs. MRI‑US fusion guided prostate biopsy

Iulia Andras, Teodora Telecan, Dana Crisan, Emanuel Cata, Pierre Kadula, David Andras, Maria Bungardean, Ioan Coman, Nicolae Crisan
Article Number: 195
Published online on: 14 October 2020

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Review

COVID‑19 and diabetes mellitus: Unraveling the hypotheses that worsen the prognosis (Review)

Radu Albulescu, Simona Olimpia Dima, Ioana Raluca Florea, Daniela Lixandru, Andreea Madalina Serban, Veronica Madalina Aspritoiu, Cristiana Tanase, Irinel Popescu, Sarah Ferber
Article Number: 194
Published online on: 14 October 2020

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Case Report

Left heart hypoplasia operated using double pulmonary arterial banding with double arterial duct stenting: A case report

Cristina Dragomir, Aniko-Maria Manea, Virgil Radu Enatescu, Alina Adriana Mara Lacatusu, Adrian Lacatusu, Osakwe Ifeanyi Henry, Marioara Boia, Constantin Ilie
Article Number: 193
Published online on: 14 October 2020

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Review

Antimicrobial peptides as an argument for the involvement of innate immunity in psoriasis (Review)

Mihail Alecu, Gabriela Coman, Alina Mușetescu, Oana Andreia Coman
Article Number: 192
Published online on: 14 October 2020

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Case Report Open Access

Hydroxyurea‑induced superinfected ulcerations: Two case reports and review of the literature

Gabriela Mariana Iancu, Anca Ocneanu, Maria Rotaru
Article Number: 191
Published online on: 14 October 2020

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Article

Prediction of NAFLD occurrence in prediabetes patients

Cosmin Mihai Vesa, Tapan Behl, Sebestian Nemeth, Ovidiu G. Bratu, Camelia C. Diaconu, Radu Dumitru Moleriu, Nicoleta Negrut, Dana C. Zaha, Cristiana Bustea, Florentina Ionita Radu, Simona Bungau
Article Number: 190
Published online on: 13 October 2020

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Article

Correlation between quality of life and disease severity of pediatric patients with atopic dermatitis

Mara Sur, Andreea Nicoleta Boca, Roxana Flavia Ilies, Emanuela Floca, Alexandru Tataru, Lucia Sur
Article Number: 189
Published online on: 13 October 2020

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Article

Role of osteodensitometry in osteoporosis and osteopenia in psoriatic arthritis

Ilarie Brihan, Angelica Hălmăjan, Daniel Boda, Simona Laura Ianoși, Gyula László Fekete, Mihaela Zdrîncă
Article Number: 188
Published online on: 13 October 2020

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Assessment of sun‑related behavior and serum vitamin D in basal cell carcinoma: Preliminary results

Corina Vornicescu, Loredana Ungureanu, Simona Corina Șenilă, Ștefan Cristian Vesa, Rodica Cosgarea, Corina Iulia Baican, Mihaela Carmen Mihu
Article Number: 187
Published online on: 13 October 2020

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Review

Non-sexual HPV transmission and role of vaccination for a better future (Review)

Aida Petca, Andreea Borislavschi, Mona Elena Zvanca, Razvan-Cosmin Petca, Florica Sandru, Mihai Cristian Dumitrascu
Article Number: 186
Published online on: 13 October 2020

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Review

Effect of inulin in the treatment of irritable bowel syndrome with constipation (Review)

Oana-Bogdana Bărboi, Irina Ciortescu, Ioan  Chirilă, Carmen Anton, Vasile Drug
Article Number: 185
Published online on: 13 October 2020

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Article

Measurement of skin viscoelasticity: A non‑invasive approach in allergic contact dermatitis

Maria-Magdalena Constantin, Stefana Bucur, Elena-Daniela Serban, Rodica Olteanu, Ovidiu Gabriel Bratu, Traian Constantin
Article Number: 184
Published online on: 13 October 2020

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Article Open Access

Outcomes of simultaneous vs. sequential pars plana vitrectomy and cataract surgery

Andreea Dana Moraru, Dănuț Costin, Radu Lucian Moraru, Daniel Constantin Branisteanu
Article Number: 183
Published online on: 13 October 2020

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Review Open Access

Influence of unilateral intravitreal bevacizumab injection on the incidence of symptomatic choroidal neovascularization in the fellow eye in patients with neovascular age‑related macular degeneration (Review)

Daniel Constantin Branisteanu, Daciana Elena Branisteanu, Crenguta Ioana Feraru, Catalina Ioana Branisteanu, Andreea Moraru, Mihail Zemba, Florian Balta
Article Number: 182
Published online on: 13 October 2020

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Article Open Access

Associated risk factors of lower limb lymphedema after treatment of cervical and endometrial cancer

Laura Florentina Rebegea, Gabriela Stoleriu, Nicuta Manolache, Cristina Serban, Mihaela Craescu, Mary-Nicoleta Lupu, Doina Carina Voinescu, Dorel Firescu, Oana Roxana Ciobotaru
Article Number: 181
Published online on: 13 October 2020

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Article Open Access

Immune cell infiltration and related core genes expression characteristics in eosinophilic and non‑eosinophilic chronic rhinosinusitis with nasal polyps

Gaoyun Xiong, Xiaoxing Xie, Qingliang Wang, Yanyan Zhang, Yanping Ge, Wei Lin, Mingqian Li
Article Number: 180
Published online on: 12 October 2020

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Article Open Access

SIRT1 promotes pulmonary artery endothelial cell proliferation by targeting the Akt signaling pathway

Liandong Xi, Lin Ruan, Xiaoguang Yao, Dong Zhang, Hongwei Yuan, Qiang Li, Cuihuan Yan
Article Number: 179
Published online on: 12 October 2020

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Endometrial changes in estrogen and progesterone receptor expression during implantation in an oocyte donation program

Eleftherios Klonos, Periklis Katopodis, Emmanouil Karteris, Evangelos Papanikolaou, Basil Tarlatzis, George Pados
Article Number: 178
Published online on: 12 October 2020

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Antiepileptic effects of exogenous β‑hydroxybutyrate on kainic acid‑induced epilepsy

Jianping Si, Yingyan Wang, Jing Xu, Jiwen Wang
Article Number: 177
Published online on: 09 October 2020

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Article Open Access

Small interfering RNA‑mediated knockdown of KRT80 suppresses colorectal cancer proliferation

Jiatian Lin, Xiaoqin Fan, Junhui Chen, Xina Xie, Hongjian Yu
Article Number: 176
Published online on: 09 October 2020

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Article Open Access

Effectiveness of transcutaneous electrical stimulation combined with artificial tears for the treatment of dry eye: A randomized controlled trial

Ming-Ming Cai, Jie Zhang
Article Number: 175
Published online on: 09 October 2020

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Incidence, laboratory diagnosis and predictors of tracheobronchial tuberculosis in patients with pulmonary tuberculosis in Chongqing, China

An-Zhou Peng, Ao Yang, Si-Ju Li, Qian Qiu, Song Yang, Yong Chen
Article Number: 174
Published online on: 09 October 2020

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Article Open Access

Clinical and molecular findings in a family expressing a novel heterozygous variant of the G elongation factor mitochondrial 1 gene

Chang Su, Fangfang Wang
Article Number: 173
Published online on: 09 October 2020

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Article Open Access

miR‑1225‑5p inhibits non‑small cell lung cancer cell proliferation, migration and invasion, and may be a prognostic biomarker

Bin Li, Fengmin Zhang, Hong Li
Article Number: 172
Published online on: 09 October 2020

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Article Open Access

HIPK2 sustains inflammatory cytokine production by promoting endoplasmic reticulum stress in macrophages

Long Xu, He Fang, Dayuan Xu, Guangyi Wang
Article Number: 171
Published online on: 09 October 2020

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Article Open Access

Sarpogrelate and rosuvastatin synergistically ameliorate aortic damage induced by hyperlipidemia in apolipoprotein E‑deficient mice

Hongyang Liu, Siwei Xu, Guihua Li, Dayuan Lou, Xiaodan Fu, Qin Lu, Liman Hao, Jingsi Zhang, Jiajie Mei, Zheng Sui, Yu Lou
Article Number: 170
Published online on: 09 October 2020

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Article Open Access

Effect of arsenic trioxide on cervical cancer and its mechanisms

Liping Zhang, Yanan Zhou, Jing Kong, Li Zhang, Mengqin Yuan, Shu Xian, Yanqing Wang, Yanxiang Cheng, Xiaofeng Yang
Article Number: 169
Published online on: 09 October 2020

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Article Open Access

Observation of hemodynamic parameters using a non-invasive cardiac output monitor system to identify predictive indicators for post-spinal anesthesia hypotension in parturients undergoing cesarean section

Pin-Hung Yeh, Yu-Jun Chang, Sheng-En Tsai
Article Number: 168
Published online on: 09 October 2020

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Article

Glutamate receptor ionotropic, kainate 1 serves as a novel tumor suppressor of colorectal carcinoma and predicts clinical prognosis

Zhong Ren, Jingzheng Liu, Liqing Yao, Jian Li, Zhipeng Qi, Bing Li
Article Number: 167
Published online on: 09 October 2020

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Case Report Open Access

Bronchogenic cyst of the stomach: A case report and literature review

Bo Sun, An-Kang Wang, Hao Chen, Bao-Lin Qian, Xiao-Kang Yi, Yu Jiang, Qiu Li, Wen-Guang Fu, Jing Li
Article Number: 166
Published online on: 09 October 2020

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Article

Impairment in locomotor activity as an objective measure of pain and analgesia in a rat model of osteoarthritis

Mohammad Alsalem, Mansour Haddad, Ahmad Altarifi, Sara A. Aldossary, Heba Kalbouneh, Ala M. Abojaradeh, Khalid El‑Salem
Article Number: 165
Published online on: 09 October 2020

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Review Open Access

Emerging role of long non‑coding RNAs in pulmonary hypertension and their molecular mechanisms (Review)

Yuhan Qin, Gaoliang Yan, Yong Qiao, Dong Wang, Erfei  Luo, Jiantong Hou, Chengchun Tang
Article Number: 164
Published online on: 09 October 2020

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Article Open Access

Circular RNA expression profiles significantly altered in UVA‑irradiated human dermal fibroblasts

Mengbi Lin, Yue Zheng, Qian Li, Yufang Liu, Qingfang Xu, Yuying Li, Wei Lai
Article Number: 163
Published online on: 09 October 2020

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Article Open Access

Safety and clinical effectiveness of intravitreal administration of bevacizumab (Lumiere®) in patients with neovascular age‑related macular degeneration

Daniel A. Benisek, Julio Manzitti, Daniel Scorsetti, Andres M. Rousselot Ascarza, Amalia A. Ascarza, Diego Gomez Rancaño, Romina Quercia, Matias Ramirez Gismondi, Mateo A. Carpio Total, María L. Scorsetti, Eduardo Spitzer, Carola Lombas, Matías Deprati, María Ines Penna, Francisco Fernández, Marcelo A. Tinelli
Article Number: 162
Published online on: 09 October 2020

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Case Report Open Access

Moyamoya disease concurrent with dural arteriovenous fistula: A case report and literature review

Kun Hou, Yuhao Zhao, Xuan Chen, Kan Xu, Jinlu Yu
Article Number: 161
Published online on: 09 October 2020

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Article Open Access

Implantable collamer lens with a central hole for residual refractive error correction after corneal refractive surgery

Jing Zhang, Fanglin He, Yan Liu, Xianqun Fan
Article Number: 160
Published online on: 07 October 2020

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Article Open Access

miR‑132 improves the cognitive function of rats with Alzheimer's disease by inhibiting the MAPK1 signal pathway

Yiming Deng, Jingyu Zhang, Xuan Sun, Gaoting Ma, Gang Luo, Zhongrong Miao, Ligang Song
Article Number: 159
Published online on: 07 October 2020

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Article Open Access

Clinical implication of serum CA125 for the prediction of malignancy in mucinous cystic neoplasms of the pancreas

Shengming Deng, Zhiyao Fan, Yitao Gong, He Cheng, Kaizhou Jin, Yunzhen Qian, Zhiwen Xiao, Yu Liu, Ruijie Wang, Yuwei Zheng, Quanxing Ni, Xianjun Yu, Chen Liu, Guopei Luo
Article Number: 158
Published online on: 07 October 2020

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Article Open Access

Influence of a combination of triptolide and ferulic acid on the activities of CYP450 enzymes and oxidative stress in HaCaT cells

Jianlin Zhang, Yongmei Guan, Liangfei He, Ling Tao, Zhenhzong Zang, Weifeng Zhu, Lihua Chen, Chen Jin
Article Number: 157
Published online on: 06 October 2020

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Article

A modified protocol for the isolation, culture, and cryopreservation of rat embryonic neural stem cells

Hengxing Zhou, Huan Yang, Lu Lu, Xueying Li, Bin Pan, Zheng Fu, Tianci Chu, Jun Liu, Yi Kang, Lu Liu, Guangzhi Ning, Wenyuan Ding, Ping Wu, Xiaohong Kong, Shiqing Feng
Article Number: 156
Published online on: 06 October 2020

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Article Open Access

Inhibition of miRNA‑29a regulates intestinal barrier function in diarrhea‑predominant irritable bowel syndrome by upregulating ZO‑1 and CLDN1

He Zhu, Xi Xiao, Yuying Shi, Yingxiu Wu, Yusheng Huang, Detang Li, Fen Xiong, Guodong He, Yuna Chai, Hongmei Tang
Article Number: 155
Published online on: 06 October 2020

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Article Open Access

TUG1 knockdown promoted viability and inhibited apoptosis and cartilage ECM degradation in chondrocytes via the miR‑17‑5p/FUT1 pathway in osteoarthritis

Zhichao Li, Jin Wang, Jing Yang
Article Number: 154
Published online on: 06 October 2020

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Article

Comparison of two regimens for patients with thyroid‑associated ophthalmopathy receiving intravenous methyl prednisolone: A single center prospective randomized trial

Pan-Wei Mu, Xi-Xiang Tang, Yi-Na Wang, Shuo Lin, Man-Man Wang, Qiong-Li Yin, Jiong Shu, Bi-Lian Zhu, Jing-Ren Li, Li Zhou, Long-Yi Zeng, Yan-Ming Chen
Article Number: 153
Published online on: 06 October 2020

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Article Open Access

A compound heterozygous mutation of the alkaline phosphatase ALPL gene causes hypophosphatasia in a Han Chinese family

Huajie Huang, Jian Wang, Yingyin Liang, Xiaofeng Wei, Dan Guo, Hengbiao Sun, Xuelian Zhang, Xiangmin Xu, Fu Xiong
Article Number: 152
Published online on: 06 October 2020

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Article Open Access

Suppressive effects of RASAL2 on renal cell carcinoma via SOX2/ERK/p38 MAPK pathway

Sen Wang, Xiaomin Hao, Sai He, Changli Liu, Qilong Wang
Article Number: 151
Published online on: 06 October 2020

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Thrombospondin‑2 is upregulated in patients with aortic dissection and enhances angiotensin II‑induced smooth muscle cell apoptosis

Liping Qi, Kui Wu, Shutian Shi, Qingwei Ji, Huangtai Miao, Que Bin
Article Number: 150
Published online on: 06 October 2020

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Article Open Access

Metformin prevents the development of monocrotaline‑induced pulmonary hypertension by decreasing serum levels of big endothelin‑1

Tomohiko Yoshida, Katsuhiro Matsuura, Seijirow Goya, Danfu Ma, Kazumi Shimada, Pitipat Kitpipatkun, Ryosuke Namiki, Akiko Uemura, Kazuhiko Suzuki, Ryou Tanaka
Article Number: 149
Published online on: 06 October 2020

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Article

Neural stem cells induce M2 polarization of macrophages through the upregulation of interleukin‑4

Zhuangqi Ji, Xianming Jiang, Yubin Li, Jian Song, Cuicui Chai, Xiaofang Lu
Article Number: 148
Published online on: 05 October 2020

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Circadian clock gene Period2 suppresses human chronic myeloid leukemia cell proliferation

Na Wang, Miaomiao Mi, Xiaonan Wei, Chengming Sun
Article Number: 147
Published online on: 05 October 2020

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Comparison of clinical efficacy of oxcarbazepine and lamotrigine combined with escitalopram, and impact on prognostic quality of life in treating patients with epilepsy and depressive disorder

Xiaoguang Zhang, Wenli Zhao
Article Number: 146
Published online on: 05 October 2020

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Human umbilical cord‑derived mesenchymal stem cells and human cord blood mononuclear cells protect against cisplatin‑induced acute kidney injury in rat models

Qian Xu, Ping Yan, Xiang-Jie Duan, Xi Wu, Xiao-Jun Chen, Min Luo, Jing-Cheng Peng, Li-Xin Feng, Jie Liu, Hui-Lin Zhong, Wei Cheng, Qing-Yan Zou, Shao-Bin Duan
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Expression profiles of long non‑coding RNAs during fetal lung development

Jin-Xin Shen, Zhi-Dan Bao, Wen Zhu, Cheng-Ling Ma, Yan-Qing Shen, Qing Kan, Xiao-Guang Zhou, Yang Yang, Xiao-Yu Zhou
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Published online on: 05 October 2020

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Correlation between prostate‑specific antigen and four renal function‑associated parameters in different ethnicities in southwest China

Ruicen Li, Huairong Tang, Ting Bao, Hanwei Yang, Tao Jin
Article Number: 143
Published online on: 05 October 2020

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Schisandrin B exerts hypnotic effects in PCPA‑treated rats by increasing hypothalamic 5‑HT and γ‑aminobutyric acid levels

Mengyang Wang, Ning Li, Shu Jing, Chunmei Wang, Jinghui Sun, He Li, Jiale Liu, Jianguang Chen
Article Number: 142
Published online on: 05 October 2020

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Expression and predictive value of HIF‑1α and VEGF in patients with burns following treatment

Zhufeng Liu, Ling Liu, Xuejuan Cheng, Liming Gao
Article Number: 141
Published online on: 05 October 2020

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Telmisartan alleviates collagen type III glomerulopathy: A case report with literature review

Qiaoyan Guo, Lihua Liu, Ping Nie, Ping Luo
Article Number: 140
Published online on: 05 October 2020

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Ophiopogonin D attenuates PM2.5‑induced inflammation via suppressing the AMPK/NF‑κB pathway in mouse pulmonary epithelial cells

Ying Wang, Dan Li, Lei Song, Hui Ding
Article Number: 139
Published online on: 05 October 2020

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Silencing of methyltransferase‑like 3 inhibits oesophageal squamous cell carcinoma

Wen Hu, Wei Liu, Hengxing Liang, Chunmin Zhang, Min Zou, Bibo Zou
Article Number: 138
Published online on: 02 October 2020

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LINC00210 exerts oncogenic roles in glioma by sponging miR‑328

Zhifei Wang, Hao Wu, Hui Yan, Tao Cai, Jin Dai, Qiang Liu
Article Number: 137
Published online on: 02 October 2020

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Diagnostic efficacy of intravascular ultrasound combined with Gd2O3‑EPL contrast agent for patients with atherosclerosis

Shuangli Zhu, Chaoyang Wen, Dongxue Bai, Meiying Gao
Article Number: 136
Published online on: 02 October 2020

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The effect of maternal high‑fat‑diet mediated oxidative stress on ovarian function in mice offspring

Shi Yan, Fengjuan Wang, Qingyun Shi
Article Number: 135
Published online on: 02 October 2020

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Effects of different diet‑induced postnatal catch‑up growth on glycolipid metabolism in intrauterine growth retardation male rats

Yixi Wu, Guoshu Yin, Ping Wang, Zhihua Huang, Shaoda Lin
Article Number: 134
Published online on: 02 October 2020

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Comparison of the safety of brivaracetam at various doses among patients with epilepsy: A network meta‑analysis of randomized controlled trials

Ying Meng, Jiahuan Wu, Jianxin Shi, Wenyu Weng, Zhikun Zhou
Article Number: 133
Published online on: 02 October 2020

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Modulation of SERCA2a expression and function by ultrasound‑guided myocardial gene transfection

Zhongshan Gou, Xinxin Yan, Hongjing Jia, Kangyun  Sun, Ping Li, Qian Zhang, Xuedong Deng
Article Number: 132
Published online on: 02 October 2020

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Follicular fluid estradiol is an improved predictor of in vitro fertilization/intracytoplasmic sperm injection and embryo transfer outcomes

Yan Lv, Shengye Du, Xin Huang, Cuifang Hao
Article Number: 131
Published online on: 02 October 2020

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Comparison of the efficacy of ambroxol hydrochloride and N‑acetylcysteine in the treatment of children with bronchopneumonia and their influence on prognosis

Hongbo Liu, Wenxiao Wang, Xingjuan Gao
Article Number: 130
Published online on: 01 October 2020

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lncRNA‑MALAT1 expression in patients with coronary atherosclerosis and its predictive value for in‑stent restenosis

Shi Qiu, Jinhui Sun
Article Number: 129
Published online on: 01 October 2020

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miR‑155 induces endothelial cell apoptosis and inflammatory response in atherosclerosis by regulating Bmal1

Shuangchao Liang, Jiqiong Hu, Andong Zhang, Fangkuan Li, Xiaoqiang Li
Article Number: 128
Published online on: 01 October 2020

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Analysis of risk factors of diabetes peripheral neuropathy in type 2 diabetes mellitus and nursing intervention

Zhifang Li, Xianlian Lei, Bing Xu, Suyun Wang, Tiantian Gao, Hongmei Lv
Article Number: 127
Published online on: 01 October 2020

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The combination of PLLA/PLGA/PCL composite scaffolds integrated with BMP‑2‑loaded microspheres and low‑intensity pulsed ultrasound alleviates steroid‑induced osteonecrosis of the femoral head

Hanxiao Zhu, Zhongli Shi, Xunzi Cai, Xiaobo Yang, Chenhe Zhou
Article Number: 126
Published online on: 24 September 2020

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MicroRNA‑142 protects MC3T3‑E1 cells against high glucose‑induced apoptosis by targeting β‑catenin

Tiansheng Zheng, Guanglin Ji, Jincai Chen, Jinliang Lai, Tong Liu, Jianwen Mo, Qi Jin
Article Number: 125
Published online on: 24 September 2020

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Review

Roles of klotho and stem cells in mediating vascular calcification (Review)

Liangzhu Yu, Mincai Li
Article Number: 124
Published online on: 24 September 2020

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January-2026 Volume 31 Issue 1

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Adiposity indices and bone health amongst Malaysian adults: Evidence from a cross‑sectional study

Wenjian Zhao, Weizheng Zhang, Kok-Yong Chin, Xiaodong Ma, Hashwin Singh Tejpal Singh, Sophia Ogechi Ekeuku, Yuanzhong Wang, Xia Ji, Yang Guo, Sok Kuan Wong, Norliza Muhammad, Teh Rohaila Jamil, Saharuddin Ahmad
Article Number: 28
Published online on: 21 November 2025

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Ginsenoside Re attenuates homocysteine‑induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling

Shaolin Li, Chenge Zhao, Shengqin Yu, Kaijing Yang, Shuying Zhang, Sixu Liu
Article Number: 27
Published online on: 21 November 2025

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Case Report Open Access

Intussusception of the initial jejunum secondary to adenoma in the third and fourth portions of the duodenum: A case report

Lingbo Huo, Lixing Ma
Article Number: 26
Published online on: 21 November 2025

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Correction Open Access

[Corrigendum] Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β‑catenin signaling pathway

Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
Article Number: 25
Published online on: 19 November 2025

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Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

Shengbin Han, Jingzhe Xu, Chenchen Yu, Hongxi Guan, Shun Ding
Article Number: 24
Published online on: 18 November 2025

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[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 23
Published online on: 17 November 2025

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Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

Jinqi Yan, Xiaohu Wang, Chen Liang
Article Number: 22
Published online on: 14 November 2025

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Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

Mingxin He, Feng Chen, Xiaomin Xian, Zhi Guo
Article Number: 21
Published online on: 14 November 2025

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Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

Yunching Lai, Xiaolei Chen, Hebing Zhou
Article Number: 20
Published online on: 10 November 2025

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Diagnostic challenge of aneurysmal dermatofibroma mimicking cutaneous metastasis in a patient with lung cancer: A case report

Jong Yun Choi, Heeyang Park, Jangyoun Choi
Article Number: 19
Published online on: 10 November 2025

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[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Article Number: 18
Published online on: 10 November 2025

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Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study

Jeng-Yuan Yao, De-Tian-Yu Tzeng, Cai-Hong Feng, Gong-Man Xiao, Tian-Ni You, Ru-Yu Zheng
Article Number: 17
Published online on: 06 November 2025

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Chronic maxillary sinusitis masquerading as a maxillary sinus neoplasm: A case report

Ji-Hyeon Oh, Seong-Gon Kim, Su-Young Kim
Article Number: 16
Published online on: 04 November 2025

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[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
Article Number: 15
Published online on: 04 November 2025

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A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

Jingqiao Li, Yipeng Yang, Xu Zhang, Dandan Zhang, Yadong Yu, Rong Chen, Wei Du
Article Number: 14
Published online on: 30 October 2025

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Primary epithelioid angiomatous nodule of the vocal cord: A case report and literature review

Keda Li, Bin Huang, Lubing Cai, Mingqi Huang, Jianping Shi, Mingdi Jin, Ning Qian, Yongkang Guo
Article Number: 13
Published online on: 29 October 2025

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Hepatic perivascular epithelioid cell tumor: A rare mesenchymal tumor with epithelioid features: A case report

Mahmoud Abbas, Benjamin Strücker, Mehmet Haluk Morgül, Andreas Pascher, Wolfgang Hartmann, Eva Wardelmann
Article Number: 12
Published online on: 29 October 2025

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[Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet

Lei Huang, Chao Ding, Xinmin Si
Article Number: 11
Published online on: 29 October 2025

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Article

Evaluation of total oxidant status/total antioxidant capacity and DNA damage in neonates with high lactate levels in umbilical cord blood gases

Burcu Cebeci, Aydemir Yalvaç, Derya Büyükkayhan, Dilek Kurnaz, Hakan Çakir, Murat Elevli
Article Number: 10
Published online on: 29 October 2025

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Treatment of a mandibular molar with primary failure of eruption: A case report

Ming Guo, Weisheng Zhang
Article Number: 9
Published online on: 29 October 2025

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Effect of the water‑soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells

Xinghuanyu Xu, Lin Liu, Wenbai Zhang, Pu Xu
Article Number: 8
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

Xiao Ma, Jingjing Ma, Han Zhang, Xiaodong Jia, Tianrui Wang, Shanshan Ma, Yingze Zhang
Article Number: 4
Published online on: 21 October 2025

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Epimedin C: A promising neuroprotective agent that can participate in mediating the JNK/Nrf2/HO‑1 signaling pathway to prevent neurodegenerative diseases

Chao Cong, Xuan-Ling Li, Guang-Yao Lin, Lian-Wei Xu
Article Number: 3
Published online on: 21 October 2025

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Application of pleural effusion cell blocks for immunohistochemistry and EGFR gene mutation testing for advanced lung cancer

Shouxiang Zhao, Yuhong Liu, Tao Wang, Ying Li, Ze Chen, Xiaoshan Cai
Article Number: 2
Published online on: 21 October 2025

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[Corrigendum] Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility in vitro

Huan Wang, Tingtao Chen, Yidan Chen, Tao Luo, Buzhen Tan, Houyang Chen, Hongbo Xin
Article Number: 1
Published online on: 16 October 2025

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February-2026 Volume 31 Issue 2

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Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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