Vaccination in multiple sclerosis ‑ Challenging practices (Review)

  • Authors:
    • Carmen Adella Sirbu
    • Anca Alexandra Florea
    • Minerva Claudia Ghinescu
    • Any Docu‑Axelerad
    • Anca Maria Sirbu
    • Ovidiu Gabriel Bratu
    • Florentina Ionita Radu
  • View Affiliations

  • Published online on: October 15, 2020     https://doi.org/10.3892/etm.2020.9347
  • Article Number: 217
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Abstract

Infections are an ever‑present problem in the medical community, even more so for patients with multiple sclerosis (MS), for whom these infections have been linked to relapses and neurological disabilities. Even though it was believed that MS can be caused by an infection, research does not support this theory. MS is a chronic inflammatory disease considered to be autoimmune. Vaccination is proven to be one of the most effective means to prevent infections, but still it is surrounded by controversy in the general populations, as well as in the MS group. Vaccines are generally considered safe for MS patients. The exceptions from this, which turn into contraindications, are a medical history of allergic reactions to one of the vaccine components and immunosuppressed patients in the particular case of live vaccines. Given the presumed autoimmunity of the disease, some medication for MS is immunosuppressive and any live vaccine should be administered before starting treatment. Although there is still confusion regarding this subject, the current guidelines have clearer recommendations about vaccinations in MS patients and especially in treated MS patients.
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December-2020
Volume 20 Issue 6

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Spandidos Publications style
Sirbu CA, Florea AA, Ghinescu MC, Docu‑Axelerad A, Sirbu AM, Bratu OG and Radu FI: Vaccination in multiple sclerosis ‑ Challenging practices (Review). Exp Ther Med 20: 217, 2020
APA
Sirbu, C.A., Florea, A.A., Ghinescu, M.C., Docu‑Axelerad, A., Sirbu, A.M., Bratu, O.G., & Radu, F.I. (2020). Vaccination in multiple sclerosis ‑ Challenging practices (Review). Experimental and Therapeutic Medicine, 20, 217. https://doi.org/10.3892/etm.2020.9347
MLA
Sirbu, C. A., Florea, A. A., Ghinescu, M. C., Docu‑Axelerad, A., Sirbu, A. M., Bratu, O. G., Radu, F. I."Vaccination in multiple sclerosis ‑ Challenging practices (Review)". Experimental and Therapeutic Medicine 20.6 (2020): 217.
Chicago
Sirbu, C. A., Florea, A. A., Ghinescu, M. C., Docu‑Axelerad, A., Sirbu, A. M., Bratu, O. G., Radu, F. I."Vaccination in multiple sclerosis ‑ Challenging practices (Review)". Experimental and Therapeutic Medicine 20, no. 6 (2020): 217. https://doi.org/10.3892/etm.2020.9347