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Review

Vaccination in multiple sclerosis ‑ Challenging practices (Review)

  • Authors:
    • Carmen Adella Sirbu
    • Anca Alexandra Florea
    • Minerva Claudia Ghinescu
    • Any Docu‑Axelerad
    • Anca Maria Sirbu
    • Ovidiu Gabriel Bratu
    • Florentina Ionita Radu
  • View Affiliations / Copyright

    Affiliations: Department of Medical‑Surgical and Prophylactical Disciplines, Faculty of Medicine, Titu Maiorescu University, 031593 Bucharest, Romania, Department of Neurology, ‘Dr Carol Davila’ Central Military Emergency University Hospital, 010242 Bucharest, Romania, Department of Neurology, Faculty of Medicine, ‘Ovidius’ University of Constanta, 900527 Constanta, Romania, Department of Endocrinology, National Institute of Endocrinology, CI Parhon, 011863 Bucharest, Romania, Department of Urology, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania
  • Article Number: 217
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    Published online on: October 15, 2020
       https://doi.org/10.3892/etm.2020.9347
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Abstract

Infections are an ever‑present problem in the medical community, even more so for patients with multiple sclerosis (MS), for whom these infections have been linked to relapses and neurological disabilities. Even though it was believed that MS can be caused by an infection, research does not support this theory. MS is a chronic inflammatory disease considered to be autoimmune. Vaccination is proven to be one of the most effective means to prevent infections, but still it is surrounded by controversy in the general populations, as well as in the MS group. Vaccines are generally considered safe for MS patients. The exceptions from this, which turn into contraindications, are a medical history of allergic reactions to one of the vaccine components and immunosuppressed patients in the particular case of live vaccines. Given the presumed autoimmunity of the disease, some medication for MS is immunosuppressive and any live vaccine should be administered before starting treatment. Although there is still confusion regarding this subject, the current guidelines have clearer recommendations about vaccinations in MS patients and especially in treated MS patients.
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Copy and paste a formatted citation
Spandidos Publications style
Sirbu CA, Florea AA, Ghinescu MC, Docu‑Axelerad A, Sirbu AM, Bratu OG and Radu FI: Vaccination in multiple sclerosis ‑ Challenging practices (Review). Exp Ther Med 20: 217, 2020.
APA
Sirbu, C.A., Florea, A.A., Ghinescu, M.C., Docu‑Axelerad, A., Sirbu, A.M., Bratu, O.G., & Radu, F.I. (2020). Vaccination in multiple sclerosis ‑ Challenging practices (Review). Experimental and Therapeutic Medicine, 20, 217. https://doi.org/10.3892/etm.2020.9347
MLA
Sirbu, C. A., Florea, A. A., Ghinescu, M. C., Docu‑Axelerad, A., Sirbu, A. M., Bratu, O. G., Radu, F. I."Vaccination in multiple sclerosis ‑ Challenging practices (Review)". Experimental and Therapeutic Medicine 20.6 (2020): 217.
Chicago
Sirbu, C. A., Florea, A. A., Ghinescu, M. C., Docu‑Axelerad, A., Sirbu, A. M., Bratu, O. G., Radu, F. I."Vaccination in multiple sclerosis ‑ Challenging practices (Review)". Experimental and Therapeutic Medicine 20, no. 6 (2020): 217. https://doi.org/10.3892/etm.2020.9347
Copy and paste a formatted citation
x
Spandidos Publications style
Sirbu CA, Florea AA, Ghinescu MC, Docu‑Axelerad A, Sirbu AM, Bratu OG and Radu FI: Vaccination in multiple sclerosis ‑ Challenging practices (Review). Exp Ther Med 20: 217, 2020.
APA
Sirbu, C.A., Florea, A.A., Ghinescu, M.C., Docu‑Axelerad, A., Sirbu, A.M., Bratu, O.G., & Radu, F.I. (2020). Vaccination in multiple sclerosis ‑ Challenging practices (Review). Experimental and Therapeutic Medicine, 20, 217. https://doi.org/10.3892/etm.2020.9347
MLA
Sirbu, C. A., Florea, A. A., Ghinescu, M. C., Docu‑Axelerad, A., Sirbu, A. M., Bratu, O. G., Radu, F. I."Vaccination in multiple sclerosis ‑ Challenging practices (Review)". Experimental and Therapeutic Medicine 20.6 (2020): 217.
Chicago
Sirbu, C. A., Florea, A. A., Ghinescu, M. C., Docu‑Axelerad, A., Sirbu, A. M., Bratu, O. G., Radu, F. I."Vaccination in multiple sclerosis ‑ Challenging practices (Review)". Experimental and Therapeutic Medicine 20, no. 6 (2020): 217. https://doi.org/10.3892/etm.2020.9347
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