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Case Report Open Access

Cumulative visual impact of two coagulability disorders: A case report

  • Authors:
    • Horia T. Stanca
    • Bogdana Tăbăcaru
    • Florian Baltă
    • Monica Mălăescu
    • Simona Stanca
    • Mihnea Munteanu
    • Diana-Maria Dărăbuș
    • Cosmin Roșca
    • Adrian Cosmin Teodoru
  • View Affiliations / Copyright

    Affiliations: Department of Ophthalmology, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Ophthalmology, Faculty of Medicine, ‘Lucian Blaga’ University, 550159 Sibiu, Romania, Department of Pediatrics, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Ophthalmology, ‘Victor Babeș’ University of Medicine and Pharmacy, 300041 Timisoara, Romania, Department of Ophthalmology, Oculens Clinic, 400501 Cluj‑Napoca, Romania
    Copyright: © Stanca et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 218
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    Published online on: October 15, 2020
       https://doi.org/10.3892/etm.2020.9348
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Abstract

Cumulative visual impact of two coagulability disorders were reviewed by presenting a case of a young female patient with a spontaneous abortion and two thromboembolic events in 8 years, whose visual function was severely affected. The particularities of her genetic constellation regarding the retinal circulation are also discussed. The patient developed a central retinal artery occlusion in the right eye during pregnancy in 2010, which led to an extended hematological workup that revealed presence of MTHFR C677T and MTHFR A1298C heterozygote mutations. The screening for myeloproliferative disorders showed JAK2 V617F gene mutation. Test results confirmed the diagnosis of thrombophilia and essential thrombocythemia and she was recommended permanent treatment with low molecular weight heparin, platelet antiaggregant, peripheral vasodilator and neuroprotectors. Despite the treatment, the patient developed central retinal vein occlusion in the fellow eye 8 years after the first thromboembolic event. The visual acuity for the right eye (0.9 logMAR) remained poor and the visual acuity for the left eye recovered completely (from 0.3 logMAR to 0 logMAR). However, new retinal artery or vein occlusions could occur in the future and there is also a risk of thrombosis in other areas, such as cerebral, pulmonary or renal, due to the general coagulability imbalance.
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Copy and paste a formatted citation
Spandidos Publications style
Stanca HT, Tăbăcaru B, Baltă F, Mălăescu M, Stanca S, Munteanu M, Dărăbuș D, Roșca C and Teodoru AC: Cumulative visual impact of two coagulability disorders: A case report. Exp Ther Med 20: 218, 2020.
APA
Stanca, H.T., Tăbăcaru, B., Baltă, F., Mălăescu, M., Stanca, S., Munteanu, M. ... Teodoru, A.C. (2020). Cumulative visual impact of two coagulability disorders: A case report. Experimental and Therapeutic Medicine, 20, 218. https://doi.org/10.3892/etm.2020.9348
MLA
Stanca, H. T., Tăbăcaru, B., Baltă, F., Mălăescu, M., Stanca, S., Munteanu, M., Dărăbuș, D., Roșca, C., Teodoru, A. C."Cumulative visual impact of two coagulability disorders: A case report". Experimental and Therapeutic Medicine 20.6 (2020): 218.
Chicago
Stanca, H. T., Tăbăcaru, B., Baltă, F., Mălăescu, M., Stanca, S., Munteanu, M., Dărăbuș, D., Roșca, C., Teodoru, A. C."Cumulative visual impact of two coagulability disorders: A case report". Experimental and Therapeutic Medicine 20, no. 6 (2020): 218. https://doi.org/10.3892/etm.2020.9348
Copy and paste a formatted citation
x
Spandidos Publications style
Stanca HT, Tăbăcaru B, Baltă F, Mălăescu M, Stanca S, Munteanu M, Dărăbuș D, Roșca C and Teodoru AC: Cumulative visual impact of two coagulability disorders: A case report. Exp Ther Med 20: 218, 2020.
APA
Stanca, H.T., Tăbăcaru, B., Baltă, F., Mălăescu, M., Stanca, S., Munteanu, M. ... Teodoru, A.C. (2020). Cumulative visual impact of two coagulability disorders: A case report. Experimental and Therapeutic Medicine, 20, 218. https://doi.org/10.3892/etm.2020.9348
MLA
Stanca, H. T., Tăbăcaru, B., Baltă, F., Mălăescu, M., Stanca, S., Munteanu, M., Dărăbuș, D., Roșca, C., Teodoru, A. C."Cumulative visual impact of two coagulability disorders: A case report". Experimental and Therapeutic Medicine 20.6 (2020): 218.
Chicago
Stanca, H. T., Tăbăcaru, B., Baltă, F., Mălăescu, M., Stanca, S., Munteanu, M., Dărăbuș, D., Roșca, C., Teodoru, A. C."Cumulative visual impact of two coagulability disorders: A case report". Experimental and Therapeutic Medicine 20, no. 6 (2020): 218. https://doi.org/10.3892/etm.2020.9348
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