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Update on COVID‑19: A teleconference with the Paediatric Virology Study Group (Review)

  • Authors:
    • Vasilios Tzilas
    • Demosthenes Bouros
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    Affiliations: First Academic Department of Pneumonology, National and Kapodistrian University of Athens School of Medicine, 11527 Athens, Greece
    Copyright: © Tzilas et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 293
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    Published online on: October 30, 2020
       https://doi.org/10.3892/etm.2020.9423
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Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is transmitted to humans mainly via contact and droplet transmission and its entry into cells is mediated by the efficient binding of the spike (S) viral protein with the angiotensin converting enzyme‑2 (ACE2) receptors. Although acute respiratory distress syndrome (ARDS) caused by SARS‑CoV‑2 fulfills the criteria of the Berlin definition, in a considerable proportion of patients with COVID‑19, there is a dissociation between their relatively well‑preserved lung mechanics and the severity of hypoxaemia. The extent of pneumococcal related morbidity and mortality is largely unknown. Respiratory comorbidities that increase the risk of severe disease and mortality due to SARS‑CoV‑2 include chronic obstructive pulmonary disease, asthma, bronchiectasis and fibrotic interstitial lung diseases, regardless of aetiology. Pneumococcal and seasonal influenza vaccinations are useful in preventing a substantial burden of mortality in high‑risk populations, while general quarantine and social distancing can reduce the infiltration of the virus within the community. To date, several therapeutic agents have been studied or are currently examined, such as hydroxychloroquine, chloroquine, ritonavir/lopinavir, remdesivir, colchicines and interleukin‑6 inhibitors. However, the usage of most of these into clinical practice was not based on randomised clinical trials and their results should be viewed with extreme caution; remdesivir seems to be the more promising option. Rigorous efforts are under way for the development of a safe and successful vaccine against SARS‑CoV‑2.
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1 

Morawska L and Milton DK: It is time to address airborne transmission of coronavirus disease 2019 (COVID-19). Clin Infect Dis: July 6, 2020 (Epub ahead of print).

2 

Zhang R, Li Y, Zhang AL, Wang Y and Molina MJ: Identifying airborne transmission as the dominant route for the spread of COVID-19. Proc Natl Acad Sci USA. 117:14857–18863. 2020.PubMed/NCBI View Article : Google Scholar

3 

Yan J, Grantham M, Pantelic J, Bueno de Mesquita PJ, Albert B, Liu F, Ehrman S and Milton DK: EMIT Consortium. Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community. Proc Natl Acad Sci USA. 115:1081–1086. 2018.PubMed/NCBI View Article : Google Scholar

4 

Xie X, Li Y, Chwang AT, Ho PL and Seto WH: How far droplets can move in indoor environments - revisiting the Wells evaporation-falling curve. Indoor Air. 17:211–225. 2007.PubMed/NCBI View Article : Google Scholar

5 

van Doremalen N, Bushmaker T, Morris DH, Holbrook MG, Gamble A, Williamson BN, Tamin A, Harcourt JL, Thornburg NJ, Gerber SI, et al: Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med. 382:1564–1567. 2020.PubMed/NCBI View Article : Google Scholar

6 

Chia PY, Coleman KK, Tan YK, Ong SWX, Gum M, Lau SK, Lim XF, Lim AS, Sutjipto S, Lee PH, et al: Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients. Nat Commun. 11(2800)2020.PubMed/NCBI View Article : Google Scholar

7 

Guo ZD, Wang ZY, Zhang SF, Li X, Li L, Li C, Cui Y, Fu RB, Dong YZ, Chi XY, et al: Aerosol and surface distribution of severe acute respiratory syndrome coronavirus 2 in hospital wards, Wuhan, China, 2020. Emerg Infect Dis. 26:1583–1591. 2020.PubMed/NCBI View Article : Google Scholar

8 

Ong SWX, Tan YK, Chia PY, Lee TH, Ng OT, Wong MSY and Marimuthu K: Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient. JAMA. 323:1610–1612. 2020.PubMed/NCBI View Article : Google Scholar

9 

Verdecchia P, Cavallini C, Spanevello A and Angeli F: The pivotal link between ACE2 deficiency and SARS-CoV-2 infection. Eur J Intern Med. 76:14–20. 2020.PubMed/NCBI View Article : Google Scholar

10 

Bertram S, Heurich A, Lavender H, Gierer S, Danisch S, Perin P, Lucas JM, Nelson PS, Pöhlmann S and Soilleux EJ: Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts. PLoS One. 7(e35876)2012.PubMed/NCBI View Article : Google Scholar

11 

Sungnak W, Huang N, Bécavin C, Berg M, Queen R, Litvinukova M, Talavera-López C, Maatz H, Reichart D, Sampaziotis F, et al: SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. Nat Med. 26:681–687. 2020.PubMed/NCBI View Article : Google Scholar

12 

Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, Si HR, Zhu Y, Li B, Huang CL, et al: A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 579:270–273. 2020.PubMed/NCBI View Article : Google Scholar

13 

Qi F, Qian S, Zhang S and Zhang Z: Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses. Biochem Biophys Res Commun. 526:135–140. 2020.PubMed/NCBI View Article : Google Scholar

14 

ARDS Definition Task Force. Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, Camporota L and Slutsky AS: Acute respiratory distress syndrome: The Berlin definition. JAMA. 307:2526–2533. 2012.PubMed/NCBI View Article : Google Scholar

15 

Gattinoni L, Coppola S, Cressoni M, Busana M, Rossi S and Chiumello D: COVID-19 does not lead to a ‘typical’ acute respiratory distress syndrome. Am J Respir Crit Care Med. 201:1299–1300. 2020.PubMed/NCBI View Article : Google Scholar

16 

Gattinoni L, Chiumello D, Caironi P, Busana M, Romitti F, Brazzi L and Camporota L: COVID-19 pneumonia: Different respiratory treatments for different phenotypes? Intensive Care Med. 46:1099–1102. 2020.PubMed/NCBI View Article : Google Scholar

17 

Robba C, Battaglini D, Ball L, Patroniti N, Loconte M, Brunetti I, Vena A, Giacobbe DR, Bassetti M, Rocco PRM and Pelosi P: Distinct phenotypes require distinct respiratory management strategies in severe COVID-19. Respir Physiol Neurobiol. 279(103455)2020.PubMed/NCBI View Article : Google Scholar

18 

Lansbury L, Lim B, Baskaran V and Lim WS: Co-infections in people with COVID-19: a systematic review and meta-analysis. J Infect. 81:266–275. 2020.PubMed/NCBI View Article : Google Scholar

19 

Morens DM, Taubenberger JK and Fauci AS: Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: Implications for pandemic influenza preparedness. J Infect Dis. 198:962–970. 2008.PubMed/NCBI View Article : Google Scholar

20 

Brundage JF: Interactions between influenza and bacterial respiratory pathogens: Implications for pandemic preparedness. Lancet Infect Dis. 6:303–312. 2006.PubMed/NCBI View Article : Google Scholar

21 

Chien YW, Klugman KP and Morens DM: Bacterial pathogens and death during the 1918 influenza pandemic. N Engl J Med. 361:2582–2583. 2009.PubMed/NCBI View Article : Google Scholar

22 

MacIntyre CR, Chughtai AA, Barnes M, Ridda I, Seale H, Toms R and Heywood A: The role of pneumonia and secondary bacterial infection in fatal and serious outcomes of pandemic influenza a(H1N1)pdm09. BMC Infect Dis. 18(637)2018.PubMed/NCBI View Article : Google Scholar

23 

Thindwa D, Garcia Quesada M, Liu Y, Bennett J, Cohen C, Knoll MD, von Gottberg A, Hayford K and Flasche S: Use of seasonal influenza and pneumococcal polysaccharide vaccines in older adults to reduce COVID-19 mortality. Vaccine. 38:5398–5401. 2020.PubMed/NCBI View Article : Google Scholar

24 

Simpson S, Kay FU, Abbara S, Bhalla S, Chung JH, Chung M, Henry TS, Kanne JP, Kligerman S, Ko JP and Litt H: Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA. Radiol Cardiothorac Imaging. 2(e200152)2020.PubMed/NCBI View Article : Google Scholar

25 

Li W, Zhang B, Lu J, Liu S, Chang Z, Cao P, Liu X, Zhang P, Ling Y, Tao K and Chen J: The characteristics of household transmission of COVID-19. Clin Infect Dis: April 17, 2020 (Epub ahead of print).

26 

Zhang J, Litvinova M, Liang Y, Wang Y, Wang W, Zhao S, Wu Q, Merler S, Viboud C, Vespignani A, et al: Changes in contact patterns shape the dynamics of the COVID-19 outbreak in China. Science. 368:1481–1486. 2020.PubMed/NCBI View Article : Google Scholar

27 

Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, Zhang W, Wang Y, Bao S, Li Y, et al: SARS-CoV-2 infection in children. N Engl J Med. 382:1663–1665. 2020.PubMed/NCBI View Article : Google Scholar

28 

Wu Z and McGoogan JM: Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72,314 cases From the Chinese Center for Disease Control and Prevention. JAMA. 323:1239–1242. 2020.PubMed/NCBI View Article : Google Scholar

29 

Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z and Tong S: Epidemiology of COVID-19 among children in China. Pediatrics. 145(e20200702)2020.PubMed/NCBI View Article : Google Scholar

30 

Weng NP: Aging of the immune system: How much can the adaptive immune system adapt? Immunity. 24:495–499. 2006.PubMed/NCBI View Article : Google Scholar

31 

Van Bever HP, Chng SY and Goh DY: Childhood severe acute respiratory syndrome, coronavirus infections and asthma. Pediatr Allergy Immunol. 15:206–209. 2004.PubMed/NCBI View Article : Google Scholar

32 

Saheb Sharif-Askari N, Saheb Sharif-Askari F, Alabed M, Temsah MH, Al Heialy S, Hamid Q and Halwani R: Airways expression of SARS-CoV-2 receptor, ACE2, and TMPRSS2 is lower in children than adults and increases with smoking and COPD. Mol Ther Methods Clin Dev. 18:1–6. 2020.PubMed/NCBI View Article : Google Scholar

33 

Götzinger F, Santiago-García B, Noguera-Julián A, Lanaspa M, Lancella L, Calò Carducci FI, Gabrovska N, Velizarova S, Prunk P, Osterman V, et al: COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study. Lancet Child Adolesc Health. 4:653–661. 2020.PubMed/NCBI View Article : Google Scholar

34 

Toubiana J, Poirault C, Corsia A, Bajolle F, Fourgeaud J, Angoulvant F, Debray A, Basmaci R, Salvador E, Biscardi S, et al: Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: Prospective observational study. BMJ. 369(m2094)2020.PubMed/NCBI View Article : Google Scholar

35 

Verdoni L, Mazza A, Gervasoni A, Martelli L, Ruggeri M, Ciuffreda M, Bonanomi E and D'Antiga L: An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: An observational cohort study. Lancet. 395:1771–1778. 2020.PubMed/NCBI View Article : Google Scholar

36 

Grasselli G, Pesenti A and Cecconi M: Critical care utilization for the COVID-19 outbreak in Lombardy, Italy: Early experience and forecast during an emergency response. JAMA. 323:1545–1546. 2020.PubMed/NCBI View Article : Google Scholar

37 

Remuzzi A and Remuzzi G: COVID-19 and Italy: What next? Lancet. 395:1225–1228. 2020.PubMed/NCBI View Article : Google Scholar

38 

Alhazzani W, Møller MH, Arabi YM, Loeb M, Gong MN, Fan E, Oczkowski S, Levy MM, Derde L, Dzierba A, et al: Surviving sepsis campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19). Intensive Care Med. 46:854–887. 2020.PubMed/NCBI View Article : Google Scholar

39 

Million M, Lagier JC, Gautret P, Colson P, Fournier PE, Amrane S, Hocquart M, Mailhe M, Esteves-Vieira V, Doudier B, et al: Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France. Travel Med Infect Dis. 35:101738. 2020.PubMed/NCBI View Article : Google Scholar

40 

Hung IF, Lung KC, Tso EY, Liu R, Chung TW, Chu MY, Ng YY, Lo J, Chan J, Tam AR, et al: Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: An open-label, randomised, phase 2 trial. Lancet. 395:1695–1704. 2020.PubMed/NCBI View Article : Google Scholar

41 

Goldman JD, Lye DCB, Hui DS, Marks KM, Bruno R, Montejano R, Spinner CD, Galli M, Ahn MY, Nahass RG, et al: Remdesivir for 5 or 10 days in patients with severe Covid-19. N Engl J Med: May 27, 2020 (Epub ahead of print).

42 

Beigel JH, Tomashek KM, Dodd LE, Mehta AK, Zingman BS, Kalil AC, Hohmann E, Chu HY, Luetkemeyer A, Kline S, et al: Remdesivir for the treatment of Covid-19 - Preliminary report. N Engl J Med: May 22, 2020 (Epub ahead of print).

43 

Deftereos SG, Giannopoulos G, Vrachatis DA, Siasos GD, Giotaki SG, Gargalianos P, Metallidis S, Sianos G, Baltagiannis S, Panagopoulos P, et al: Effect of colchicine vs standard care on cardiac and inflammatory biomarkers and clinical outcomes in patients hospitalized with coronavirus disease 2019: The GRECCO-19 randomized clinical trial. JAMA Netw Open. 3(e2013136)2020.PubMed/NCBI View Article : Google Scholar

44 

Sciascia S, Aprà F, Baffa A, Baldovino S, Boaro D, Boero R, Bonora S, Calcagno A, Cecchi I, Cinnirella G, et al: Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in patients with severe COVID-19. Clin Exp Rheumatol. 38:529–532. 2020.PubMed/NCBI

45 

Guaraldi G, Meschiari M, Cozzi-Lepri A, Milic J, Tonelli R, Menozzi M, Franceschini E, Cuomo G, Orlando G, Borghi V, et al: Tocilizumab in patients with severe COVID-19: a retrospective cohort study. Lancet Rheumatol. 2:e474–e484. 2020.PubMed/NCBI View Article : Google Scholar

46 

Huet T, Beaussier H, Voisin O, Jouveshomme S, Dauriat G, Lazareth I, Sacco E, Naccache JM, Bézie Y, Laplanche S, et al: Anakinra for severe forms of COVID-19: A cohort study. Lancet Rheumatol. 2:e393–e400. 2020.PubMed/NCBI View Article : Google Scholar

47 

Ledford H: Chloroquine hype is derailing the search for coronavirus treatments. Nature. 580(573)2020.PubMed/NCBI View Article : Google Scholar

48 

Rosenberg ES, Dufort EM, Udo T, Wilberschied LA, Kumar J, Tesoriero J, Weinberg P, Kirkwood J, Muse A, DeHovitz J, et al: Association of treatment with hydroxychloroquine or azithromycin with in-hospital mortality in patients with COVID-19 in New York state. JAMA. 323:2493–2502. 2020.PubMed/NCBI View Article : Google Scholar

49 

No clinical benefit from use of hydroxychloroquine in hospitalised patients with COVID-19. urihttps://www.recoverytrial.net/news/statement-from-the-chief-investigators-of-the-randomised-evaluation-of-covid-19-therapy-recovery-trial-on-hydroxychloroquine-5-june-2020-no-clinical-benefit-from-use-of-hydroxychloroquine-in-hospitalised-patients-with-covid-19simplehttps://www.recoverytrial.net/news/statement-from-the-chief-investigators-of-the-randomised-evaluation-of-covid-19-therapy-recovery-trial-on-hydroxychloroquine-5-june-2020-no-clinical-benefit-from-use-of-hydroxychloroquine-in-hospitalised-patients-with-covid-19. Accessed June 5, 2020.

50 

World Health Organization (WHO): WHO discontinues hydroxychloroquine and lopinavir/ritonavir treatment arms for COVID-19.WHO, Geneva, 2020. urihttps://www.who.int/news-room/detail/04-07-2020-who-discontinues-hydroxychloroquine-and-lopinavir-ritonavir-treatment-arms-for-covid-19simplehttps://www.who.int/news-room/detail/04-07-2020-who-discontinues-hydroxychloroquine-and-lopinavir-ritonavir-treatment-arms-for-covid-19. Accessed July 4, 2020.

51 

National Institutes of Health (NIH): COVID-19 Treatment Guidelines: Coronavirus disease 2019 (COVID-19) treatment guidelines. NIH, Bethesda, MD, 2020. urihttps://www.covid19treatmentguidelines.nih.gov/simplehttps://www.covid19treatmentguidelines.nih.gov/. Accessed July 11, 2020.

52 

RECOVERY Collaborative Group. Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, Staplin N, Brightling C, Ustianowski A, et al: Effect of dexamethasone in hospitalized patients with COVID-19: Preliminary report. N Engl J Med: July 17, 2020 (Epub ahead of print).

53 

Liu J, Zheng X, Huang Y, Shan H and Huang J: Successful use of methylprednisolone for treating severe COVID-19. J Allergy Clin Immunol. 146:325–327. 2020.PubMed/NCBI View Article : Google Scholar

54 

Yang Z and Liu J, Zhou Y, Zhao X, Zhao Q and Liu J: The effect of corticosteroid treatment on patients with coronavirus infection: A systematic review and meta-analysis. J Infect. 81:e13–e20. 2020.PubMed/NCBI View Article : Google Scholar

55 

World Health Organization (WHO): Draft landscape of COVID-19 candidate vaccines. WHO, Geneva, 2020. urihttps://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccinessimplehttps://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines. Accessed September 28, 2020.

56 

Antoniou K, Raghu G, Tzilas V and Bouros D: Management of patients with interstitial lung disease in the midst of COVID-19. Respiration. 99:625–627. 2020.PubMed/NCBI View Article : Google Scholar

57 

Antoniou K, Bolaki M, Bibaki E, Vasarmidi E, Trachalaki A, Tsitoura E and Bouros D: COVID19 alert Do we know our enemy? Pneumon. 33:25–27. 2020.

58 

Bouros D: BCG vaccination and Covid-19 protection. Pneumon. 33:7–9. 2020.

59 

Sampsonas F: Bacillus Calmette-Guerin: Established and emerging roles for an old friend. Pneumon. 33:10–12. 2020.

60 

Antoniadis A, Pechlivanidou R, Bouros E and Bouros D: Stem cells and covid-19. Pneumon. 33:1–3. 2020.

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Tzilas V and Bouros D: Update on COVID‑19: A teleconference with the Paediatric Virology Study Group (Review). Exp Ther Med 20: 293, 2020.
APA
Tzilas, V., & Bouros, D. (2020). Update on COVID‑19: A teleconference with the Paediatric Virology Study Group (Review). Experimental and Therapeutic Medicine, 20, 293. https://doi.org/10.3892/etm.2020.9423
MLA
Tzilas, V., Bouros, D."Update on COVID‑19: A teleconference with the Paediatric Virology Study Group (Review)". Experimental and Therapeutic Medicine 20.6 (2020): 293.
Chicago
Tzilas, V., Bouros, D."Update on COVID‑19: A teleconference with the Paediatric Virology Study Group (Review)". Experimental and Therapeutic Medicine 20, no. 6 (2020): 293. https://doi.org/10.3892/etm.2020.9423
Copy and paste a formatted citation
x
Spandidos Publications style
Tzilas V and Bouros D: Update on COVID‑19: A teleconference with the Paediatric Virology Study Group (Review). Exp Ther Med 20: 293, 2020.
APA
Tzilas, V., & Bouros, D. (2020). Update on COVID‑19: A teleconference with the Paediatric Virology Study Group (Review). Experimental and Therapeutic Medicine, 20, 293. https://doi.org/10.3892/etm.2020.9423
MLA
Tzilas, V., Bouros, D."Update on COVID‑19: A teleconference with the Paediatric Virology Study Group (Review)". Experimental and Therapeutic Medicine 20.6 (2020): 293.
Chicago
Tzilas, V., Bouros, D."Update on COVID‑19: A teleconference with the Paediatric Virology Study Group (Review)". Experimental and Therapeutic Medicine 20, no. 6 (2020): 293. https://doi.org/10.3892/etm.2020.9423
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