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Clinical characteristics of 78 cases of patients infected with coronavirus disease 2019 in Wuhan, China

  • Authors:
    • Liying Lin
    • Canmei Zhong
    • Shanshan Rao
    • Hongguang Lin
    • Rongfeng Huang
    • Fenglin Chen
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology, Fujian Medical University Union Hospital, Fuzhou, Fujian 350000, P.R. China, Department of Critical Care Medicine, Fujian Medical University Union Hospital, Fuzhou, Fujian 350000, P.R. China, Department of Respiratory Medicine, Fujian Medical University Union Hospital, Fuzhou, Fujian 350000, P.R. China
    Copyright: © Lin et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 7
    |
    Published online on: November 4, 2020
       https://doi.org/10.3892/etm.2020.9439
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Abstract

Coronavirus disease 2019 (COVID‑19) emerged in Wuhan and rapidly spread throughout the world in December 2019. The present study aimed to describe the clinical characteristics and laboratory findings of 78 patients with COVID‑19 in order to enhance the understanding of the disease. Medical records and data of 78 patients with COVID‑19, including demographics, clinical features, laboratory findings and radiological characteristics, were collected and analyzed. Of the 78 hospitalized patients with COVID‑19, the median age was 66.5 years and 48.7% of patients were male. Hypertension and diabetes were the most common chronic underlying diseases, and the most common symptoms were a cough and a fever. Furthermore, the most common findings on the chest CT were extensive ground‑glass opacity and bilateral shadowing. Anemia and lymphocytopenia were the most common abnormalities identified during routine blood tests. COVID‑19 caused early liver renal damage, with 52.9% of patients displaying elevated D‑dimer levels, 98.7% of patients displaying elevated IL‑6 levels and 80.8% of patients displaying a reduced level of low‑density lipoprotein cholesterol (LDL‑C). In the present single‑center case study of 78 patients with COVID‑19 in Wuhan, China, the patients displayed abnormal routine blood tests, liver function, renal function and levels of D‑dimer, LDL‑C and IL‑6. Therefore, the development of drugs and vaccines that can be used to prevent and treat infections of COVID‑19 is urgently required.
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Copy and paste a formatted citation
Spandidos Publications style
Lin L, Zhong C, Rao S, Lin H, Huang R and Chen F: Clinical characteristics of 78 cases of patients infected with coronavirus disease 2019 in Wuhan, China. Exp Ther Med 21: 7, 2021.
APA
Lin, L., Zhong, C., Rao, S., Lin, H., Huang, R., & Chen, F. (2021). Clinical characteristics of 78 cases of patients infected with coronavirus disease 2019 in Wuhan, China. Experimental and Therapeutic Medicine, 21, 7. https://doi.org/10.3892/etm.2020.9439
MLA
Lin, L., Zhong, C., Rao, S., Lin, H., Huang, R., Chen, F."Clinical characteristics of 78 cases of patients infected with coronavirus disease 2019 in Wuhan, China". Experimental and Therapeutic Medicine 21.1 (2021): 7.
Chicago
Lin, L., Zhong, C., Rao, S., Lin, H., Huang, R., Chen, F."Clinical characteristics of 78 cases of patients infected with coronavirus disease 2019 in Wuhan, China". Experimental and Therapeutic Medicine 21, no. 1 (2021): 7. https://doi.org/10.3892/etm.2020.9439
Copy and paste a formatted citation
x
Spandidos Publications style
Lin L, Zhong C, Rao S, Lin H, Huang R and Chen F: Clinical characteristics of 78 cases of patients infected with coronavirus disease 2019 in Wuhan, China. Exp Ther Med 21: 7, 2021.
APA
Lin, L., Zhong, C., Rao, S., Lin, H., Huang, R., & Chen, F. (2021). Clinical characteristics of 78 cases of patients infected with coronavirus disease 2019 in Wuhan, China. Experimental and Therapeutic Medicine, 21, 7. https://doi.org/10.3892/etm.2020.9439
MLA
Lin, L., Zhong, C., Rao, S., Lin, H., Huang, R., Chen, F."Clinical characteristics of 78 cases of patients infected with coronavirus disease 2019 in Wuhan, China". Experimental and Therapeutic Medicine 21.1 (2021): 7.
Chicago
Lin, L., Zhong, C., Rao, S., Lin, H., Huang, R., Chen, F."Clinical characteristics of 78 cases of patients infected with coronavirus disease 2019 in Wuhan, China". Experimental and Therapeutic Medicine 21, no. 1 (2021): 7. https://doi.org/10.3892/etm.2020.9439
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