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Clinical efficacy of intravenous anesthesia on breast segmental surgery and its effects on oxidative stress response and hemodynamics of patients

  • Authors:
    • Xiaohong Yu
    • Yinchan Zhou
    • Xuezhen Zheng
    • Su Shao
    • Huihong He
  • View Affiliations / Copyright

    Affiliations: Department of Nursing Care, Chun'an First People's Hospital, Hangzhou, Zhejiang 311700, P.R. China, Department of Nursing Care, Chun'an Hospital of TCM, Hangzhou, Zhejiang 311700, P.R. China
    Copyright: © Yu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 11
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    Published online on: November 4, 2020
       https://doi.org/10.3892/etm.2020.9443
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Abstract

This study was designed to investigate the clinical efficacy of intravenous anesthesia on breast segmental surgery and the effects on hemodynamics of patients. A total of 267 patients were collected as research subjects. These patients underwent breast segmental surgery in Chun'an First People's Hospital from March 2015 to September 2018. Among them, 137 patients undergoing intravenous anesthesia were the research group, and 130 patients undergoing inhalation anesthesia were the control group. The following parameters were recorded: Clinical efficacy, postoperative adverse conditions, hemodynamic indicators including systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR). Visual analogue scale (VAS) was used to observe the analgesic effect of the two groups, the mental state of patients in the two groups was observed by mini‑mental state examination (MMSE) scoring method, and systemic evaluation was made by oxidative stress (OS) reaction indicators. The MMSE scores of the two groups decreased one day after surgery, but the score in the research group was higher than that in the control group (P<0.05). The levels of SBP and DBP at T1 and T2 in the control group were significantly higher than those in the research group (P<0.05). HR of research group at T1 and T2 was lower than that at T0 and that at corresponding time of control group (P<0.05). The incidence rate of postoperative adverse reactions in the research group was significantly lower than that in the control group (P<0.05). In conclusion, intravenous anesthesia for breast segmental surgery can reduce the occurrence of adverse reactions after surgery, with complete sedation and analgesia. Patients were able to wake up quickly and stably after surgery, and their cognitive function and OS recovered rapidly. However, due to the great impact on hemodynamics during surgery, attention should be paid to maintain hemodynamic stability during surgery to avoid hypotension and bradycardia.
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1 

Mahmoud M and Mason KP: Recent advances in intravenous anesthesia and anesthetics. F1000Res 7: F1000 Faculty Rev-470 F1000 Faculty Rev-470, 2018.

2 

Absalom AR and Mason KP: Total intravenous anesthesia and target controlled infusions. 2017 doi: 10.1007/978-3-319-47609-4.

3 

Poprac P, Jomova K, Simunkova M, Kollar V, Rhodes CJ and Valko M: Targeting free radicals in oxidative stress-related human diseases. Trends Pharmacol Sci. 38:592–607. 2017.PubMed/NCBI View Article : Google Scholar

4 

Athar M: Oxidative stress and experimental carcinogenesis. Indian J Exp Biol. 40:656–667. 2002.PubMed/NCBI

5 

Ishii T, Yasuda K, Akatsuka A, Hino O, Hartman PS and Ishii N: A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis. Cancer Res. 65:203–209. 2005.PubMed/NCBI

6 

Ray G, Batra S, Shukla NK, Deo S, Raina V, Ashok S and Husain SA: Lipid peroxidation, free radical production and antioxidant status in breastcancer. Breast Cancer Res Treat. 59:163–170. 2000.PubMed/NCBI View Article : Google Scholar

7 

Saygili EI, Akcay T, Konukoglu D and Papilla C: Glutathione and glutathione-related enzymes in colorectal cancer patients. J Toxicol Environ Health A. 66:411–415. 2003.PubMed/NCBI View Article : Google Scholar

8 

Höhn A, Weber D, Jung T, Ott C, Hugo M, Kochlik B, Kehm R, König J, Grune T and Castro JP: Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence. Redox Biol. 11:482–501. 2017.PubMed/NCBI View Article : Google Scholar

9 

Tain RW, Scotti AM, Li W, Zhou XJ and Cai K: Imaging short-lived reactive oxygen species (ROS) with endogenous contrast MRI. J Magn Reson Imaging. 47:222–229. 2018.PubMed/NCBI View Article : Google Scholar

10 

Davis SM and Pennypacker KR: Targeting antioxidant enzyme expression as a therapeutic strategy for ischemic stroke. Neurochem Int. 107:23–32. 2017.PubMed/NCBI View Article : Google Scholar

11 

Ahmed RG: The physiological and biochemical effects of diabetes on the balance between oxidative stress and antioxidant defense system. Med J Islamic World Acad Sci. 15:31–42. 2005.

12 

Wong A, Black SE, Yiu SYP, Au LWC, Lau AYL, Soo YOY, Chan AYY, Leung TWH, Wong LKS, Kwok TCY, et al: Converting MMSE to MoCA and MoCA 5-minute protocol in an educationally heterogeneous sample with stroke or transient ischemic attack. Int J Geriatr Psychiatry. 33:729–734. 2018.PubMed/NCBI View Article : Google Scholar

13 

Le May S, Ballard A, Khadra C, Gouin S, Plint AC, Villeneuve E, Mâsse B, Tsze DS, Neto G, Drendel AL, et al: A comparison of the psychometric properties of three pain scales used in the pediatric emergency department: VAS, FPS-R and CAS. Pain. 159:1508–1517. 2018.PubMed/NCBI View Article : Google Scholar

14 

Soleimani A, Heidari N, Habibi MR, Kiabi FH, Khademloo M, Emami Zeydi A and Sohrabi FB: Comparing hemodynamic responses to diazepam, propofol and etomidate during anesthesia induction in patients with left ventricular dysfunction undergoing coronary artery bypass graft surgery: A double-blind, randomized clinical trial. Med Arch. 71:198–203. 2017.PubMed/NCBI View Article : Google Scholar

15 

Masjedi M, Zand F, Kazemi AP and Hoseinipour A: Prophylactic effect of ephedrine to reduce hemodynamic changes associated with anesthesia induction with propofol and remifentanil. J Anaesthesiol Clin Pharmacol. 30:217–221. 2014.PubMed/NCBI View Article : Google Scholar

16 

Cho YJ, Kim TK, Hong DM, Seo JH, Bahk JH and Jeon Y: Effect of desflurane-remifentanil vs. Propofol-remifentanil anesthesia on arterial oxy genation during one-lung ventilation for thoracoscopic surgery: A prospective ran domized trial. BMC Anesthesiol. 17(9)2017.PubMed/NCBI View Article : Google Scholar

17 

Feng AY, Kaye AD, Kaye RJ, Belani K and Urman RD: Novel propofol derivatives and implications for anesthesia practice. J Anaesthesiol Clin Pharmacol. 33:9–15. 2017.PubMed/NCBI View Article : Google Scholar

18 

Battershill AJ and Keating GM: Remifentanil: A review of its analgesic and sedative use in the intensive care unit. Drugs. 66:365–385. 2006.PubMed/NCBI View Article : Google Scholar

19 

Kisilcwicz M, Rosenhcrg H and Vaillancourt C: Remifentanil for procedural sedation; a systematic review of the literature. Emerg Mcd J. 34:294–301. 2017.PubMed/NCBI View Article : Google Scholar

20 

Xu R, Zhou S, Yang J, Li H, Zhang Q, Zhang G, Xu S and Peng Q: Total intravenous anesthesia produces outcomes superior to those with combined intravenous-inhalation anesthesia for laparoscopic gynecological surgery at high altitude. J Int Med Res. 45(246)2017.PubMed/NCBI View Article : Google Scholar

21 

Visser K, Hassink EA, Bonsel GJ, Moen J and Kalkman C: Randomized controlled trial intravenous anesthesia with propofol versus inhalation anesthesia with isoflurane-nitrous oxide. Anesthesiology. 95:616–626. 2001.PubMed/NCBI View Article : Google Scholar

22 

Kim H, Choi SH, Choi YS, Lee JH, Kim NO and Lee JR: Comparison of the antitussive effect of remifentanil during recovery from propofol and sevoflurane anaesthesia. Anaesthesia. 67:765–770. 2012.PubMed/NCBI View Article : Google Scholar

23 

Scott HB, Choi SW, Wong GTC and Irwin MG: The effect of remifentanil on propofol requirements to achieve loss of response to command vs. loss of response to pain. Anaesthesia. 72:479–487. 2017.PubMed/NCBI View Article : Google Scholar

24 

Park SK and Cho EJ: A randomized controlled trial of two different interventions for the prevention of postoperative nausea and vomiting; total intravenous anaesthesia using propofol and remifentanil versus prophylactic palonosetron with inhalational anaesthesia using sevofluraef-nitrous oxide. J Int Med Res. 39:1808–1815. 2011.PubMed/NCBI View Article : Google Scholar

25 

Mohaghegh T, Yazdi B, Norouzi A, Fateh S, Modir H and Mohammadbeigi A: Effect of intravenous anesthesia with propofol versus isoflurane inhalation anesthesia in postoperative pain of inguinal herniotomy: A randomized clinical trial. Med Gas Res. 7:86–92. 2017.PubMed/NCBI View Article : Google Scholar

26 

Oncul S, Gaygusuz EA, Yilmaz M, Terzi H and Balci C: Comparison of ketamine-propofol and remifentanil in terms of hemodynamic variables and patient satisfaction during monitored anaesthesia care. Anasthesiol Intensive Ther. 48:116–121. 2016.PubMed/NCBI View Article : Google Scholar

27 

Yu W: Anesthesia with propofol and sevoflurane on postoperative cognitive function of elderly patients undergoing general thoracic surgery. Pak J Pharm Sci. 30:1107–1110. 2017.PubMed/NCBI

28 

Elbakry AE, Sultan WE and Ibrahim E: A comparison between inhalational (Desflurane) and total intravenous anaesthesia (Propofol and dexmedetomidine) in improving postoperative recovery for morbidly obese patients undergoing laparoscopic sleeve gastrectomy: A double-blinded randomised controlled trial. J Clin Anesth. 45:6–11. 2018.PubMed/NCBI View Article : Google Scholar

29 

Bellanti F, Mirabella L, Mitarotonda D, Blonda M, Tamborra R, Cinnella G, Fersini A, Ambrosi A, Dambrosio M, Vendemiale G and Serviddio G: Propofol but not sevoflurane prevents mitochondrial dysfunction and oxidative stress by limiting HIF-1α activation in hepatic ischemia/reperfusion injury. Free Radic Biol Med. 3:323–333. 2016.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Yu X, Zhou Y, Zheng X, Shao S and He H: Clinical efficacy of intravenous anesthesia on breast segmental surgery and its effects on oxidative stress response and hemodynamics of patients. Exp Ther Med 21: 11, 2021.
APA
Yu, X., Zhou, Y., Zheng, X., Shao, S., & He, H. (2021). Clinical efficacy of intravenous anesthesia on breast segmental surgery and its effects on oxidative stress response and hemodynamics of patients. Experimental and Therapeutic Medicine, 21, 11. https://doi.org/10.3892/etm.2020.9443
MLA
Yu, X., Zhou, Y., Zheng, X., Shao, S., He, H."Clinical efficacy of intravenous anesthesia on breast segmental surgery and its effects on oxidative stress response and hemodynamics of patients". Experimental and Therapeutic Medicine 21.1 (2021): 11.
Chicago
Yu, X., Zhou, Y., Zheng, X., Shao, S., He, H."Clinical efficacy of intravenous anesthesia on breast segmental surgery and its effects on oxidative stress response and hemodynamics of patients". Experimental and Therapeutic Medicine 21, no. 1 (2021): 11. https://doi.org/10.3892/etm.2020.9443
Copy and paste a formatted citation
x
Spandidos Publications style
Yu X, Zhou Y, Zheng X, Shao S and He H: Clinical efficacy of intravenous anesthesia on breast segmental surgery and its effects on oxidative stress response and hemodynamics of patients. Exp Ther Med 21: 11, 2021.
APA
Yu, X., Zhou, Y., Zheng, X., Shao, S., & He, H. (2021). Clinical efficacy of intravenous anesthesia on breast segmental surgery and its effects on oxidative stress response and hemodynamics of patients. Experimental and Therapeutic Medicine, 21, 11. https://doi.org/10.3892/etm.2020.9443
MLA
Yu, X., Zhou, Y., Zheng, X., Shao, S., He, H."Clinical efficacy of intravenous anesthesia on breast segmental surgery and its effects on oxidative stress response and hemodynamics of patients". Experimental and Therapeutic Medicine 21.1 (2021): 11.
Chicago
Yu, X., Zhou, Y., Zheng, X., Shao, S., He, H."Clinical efficacy of intravenous anesthesia on breast segmental surgery and its effects on oxidative stress response and hemodynamics of patients". Experimental and Therapeutic Medicine 21, no. 1 (2021): 11. https://doi.org/10.3892/etm.2020.9443
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