Umbilical cord lactate compared with pH as predictors of intrapartum asphyxia

  • Authors:
    • Adrian Neacsu
    • Cătălin Gabriel Herghelegiu
    • Silviu Voinea
    • Mihai Cornel Traian Dimitriu
    • Liana Ples
    • Roxana Elena Bohiltea
    • Anca Daniela Braila
    • Leonard Nastase
    • Nicolae Bacalbasa
    • Laura Ioana Chivu
    • Florentina Furtunescu
    • Raluca Gabriela Ioan
  • View Affiliations

  • Published online on: November 26, 2020     https://doi.org/10.3892/etm.2020.9513
  • Article Number: 80
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Abstract

Despite advances in fetal monitoring during labor, one of the most critical causes of neonatal death and neurologic injuries remains intrapartum asphyxia. Umbilical cord gases can be used to detect acidosis and fetal distress. We conducted a retrospective, multicenter study to evaluate umbilical cord blood pH and lactate as a mean of evaluating the degree of intrapartum hypoxia and also to establish which of the two is more reliable in predicting morbidity in term neonates. The present study utilized a total of 124 cases that met the criteria for intrapartum asphyxia and 150 normal term newborns that were randomly selected as case control. Both umbilical cord lactate and pH proved to be accurate predictors of neonatal morbidity caused by intrapartum hypoxia. Lactate proved to be superior to pH in predicting adverse neonatal outcome. The greatest sensibility and specificity in predicting intrapartum asphyxia were achieved in our study by using a cutoff value of 3.75 mmol/l for lactate and 7.24 for pH.
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January-2021
Volume 21 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Neacsu A, Herghelegiu CG, Voinea S, Dimitriu MC, Ples L, Bohiltea RE, Braila AD, Nastase L, Bacalbasa N, Chivu LI, Chivu LI, et al: Umbilical cord lactate compared with pH as predictors of intrapartum asphyxia. Exp Ther Med 21: 80, 2021.
APA
Neacsu, A., Herghelegiu, C.G., Voinea, S., Dimitriu, M.C., Ples, L., Bohiltea, R.E. ... Ioan, R.G. (2021). Umbilical cord lactate compared with pH as predictors of intrapartum asphyxia. Experimental and Therapeutic Medicine, 21, 80. https://doi.org/10.3892/etm.2020.9513
MLA
Neacsu, A., Herghelegiu, C. G., Voinea, S., Dimitriu, M. C., Ples, L., Bohiltea, R. E., Braila, A. D., Nastase, L., Bacalbasa, N., Chivu, L. I., Furtunescu, F., Ioan, R. G."Umbilical cord lactate compared with pH as predictors of intrapartum asphyxia". Experimental and Therapeutic Medicine 21.1 (2021): 80.
Chicago
Neacsu, A., Herghelegiu, C. G., Voinea, S., Dimitriu, M. C., Ples, L., Bohiltea, R. E., Braila, A. D., Nastase, L., Bacalbasa, N., Chivu, L. I., Furtunescu, F., Ioan, R. G."Umbilical cord lactate compared with pH as predictors of intrapartum asphyxia". Experimental and Therapeutic Medicine 21, no. 1 (2021): 80. https://doi.org/10.3892/etm.2020.9513