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Case Report

Implications of human T‑lymphotropic virus in pregnancy: A case report and a review of the diagnostic criteria and management proposal

  • Authors:
    • Roxana Elena Bohiltea
    • Natalia Turcan
    • Costin Berceanu
    • Octavian Munteanu
    • Tiberiu Augustin Georgescu
    • Ionita Ducu
    • Adrian Neacsu
    • Florentina Furtunescu
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania, Department of Obstetrics and Gynecology, University Emergency Hospital Bucharest, 050098 Bucharest, Romania, Department of Obstetrics Gynecology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania, Department of Pathology, Faculty of Medicine, ‘Carol Davila’ University of Medicine and Pharmacy, 050463 Bucharest, Romania, Department of Public Health and Management, Faculty of Medicine, ‘Carol Davila’ University of Medicine and Pharmacy, 050463 Bucharest, Romania
  • Article Number: 82
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    Published online on: November 26, 2020
       https://doi.org/10.3892/etm.2020.9514
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Abstract

Human T‑lymphotropic virus (HTLV) is considered to be the most highly oncogenic existing virus, being the cause of several fatal diseases such as adult T cell leukemia‑lymphoma (ATL) and HTLV‑I‑associated myelopathy (HAM). The main transmission methods are unprotected sexual intercourse, vertical transmission and breastfeeding and direct exposure to infected blood or tissue. The identification of infected mothers prior to delivery is a highly important step in preventing mother to child transmission. Universal antenatal screening for HTLV is not recommended in Romania, although there are sufficient data demonstrating the risk of vertical transmission. We present the case of an HTLV‑1-infected pregnant woman, with an aim to highlight: i) points of strategy for the management of HTLV during pregnancy; ii) the particularities of the course of pregnancy; and iii) the aspects that show the importance of knowing the status regarding the HTLV infection antepartum. The case was particular due to the ascendant proviral load during the pregnancy period, which led to the initiation of antiretroviral therapy and the particular pregnancy outcome with preterm rupture of membranes and fetal growth restriction. According to current recommendations, pregnant women infected with HTLV‑1 should be advised to refrain from donating blood, body organs, or other tissues. There is no evidence of the number of individuals infected with this virus in Romania at present, and the diagnosis can only occur by chance. A specific treatment or immunization for HTLV infection does not currently exist, thus preventive methods are the only tool to reduce the prevalence and mortality of this infection.
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Copy and paste a formatted citation
Spandidos Publications style
Bohiltea RE, Turcan N, Berceanu C, Munteanu O, Georgescu TA, Ducu I, Neacsu A and Furtunescu F: Implications of human T‑lymphotropic virus in pregnancy: A case report and a review of the diagnostic criteria and management proposal. Exp Ther Med 21: 82, 2021.
APA
Bohiltea, R.E., Turcan, N., Berceanu, C., Munteanu, O., Georgescu, T.A., Ducu, I. ... Furtunescu, F. (2021). Implications of human T‑lymphotropic virus in pregnancy: A case report and a review of the diagnostic criteria and management proposal. Experimental and Therapeutic Medicine, 21, 82. https://doi.org/10.3892/etm.2020.9514
MLA
Bohiltea, R. E., Turcan, N., Berceanu, C., Munteanu, O., Georgescu, T. A., Ducu, I., Neacsu, A., Furtunescu, F."Implications of human T‑lymphotropic virus in pregnancy: A case report and a review of the diagnostic criteria and management proposal". Experimental and Therapeutic Medicine 21.1 (2021): 82.
Chicago
Bohiltea, R. E., Turcan, N., Berceanu, C., Munteanu, O., Georgescu, T. A., Ducu, I., Neacsu, A., Furtunescu, F."Implications of human T‑lymphotropic virus in pregnancy: A case report and a review of the diagnostic criteria and management proposal". Experimental and Therapeutic Medicine 21, no. 1 (2021): 82. https://doi.org/10.3892/etm.2020.9514
Copy and paste a formatted citation
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Spandidos Publications style
Bohiltea RE, Turcan N, Berceanu C, Munteanu O, Georgescu TA, Ducu I, Neacsu A and Furtunescu F: Implications of human T‑lymphotropic virus in pregnancy: A case report and a review of the diagnostic criteria and management proposal. Exp Ther Med 21: 82, 2021.
APA
Bohiltea, R.E., Turcan, N., Berceanu, C., Munteanu, O., Georgescu, T.A., Ducu, I. ... Furtunescu, F. (2021). Implications of human T‑lymphotropic virus in pregnancy: A case report and a review of the diagnostic criteria and management proposal. Experimental and Therapeutic Medicine, 21, 82. https://doi.org/10.3892/etm.2020.9514
MLA
Bohiltea, R. E., Turcan, N., Berceanu, C., Munteanu, O., Georgescu, T. A., Ducu, I., Neacsu, A., Furtunescu, F."Implications of human T‑lymphotropic virus in pregnancy: A case report and a review of the diagnostic criteria and management proposal". Experimental and Therapeutic Medicine 21.1 (2021): 82.
Chicago
Bohiltea, R. E., Turcan, N., Berceanu, C., Munteanu, O., Georgescu, T. A., Ducu, I., Neacsu, A., Furtunescu, F."Implications of human T‑lymphotropic virus in pregnancy: A case report and a review of the diagnostic criteria and management proposal". Experimental and Therapeutic Medicine 21, no. 1 (2021): 82. https://doi.org/10.3892/etm.2020.9514
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