Manometric changes of the esophagus in morbidly obese patients

Popescu,Andrada L.; Costache,Raluca S.; Costache,Daniel O.; Balaban,Vasile D.; Jinga,Mariana; Ionita‑Radu,Florentina; Caruntu,Ana; Fierbinteanu‑Braticevici,Carmen

doi:10.3892/etm.2021.10036

June-2021 Volume 21 Issue 6

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June-2021 Volume 21 Issue 6

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Article

Manometric changes of the esophagus in morbidly obese patients

Authors:
- Andrada L. Popescu
- Raluca S. Costache
- Daniel O. Costache
- Vasile D. Balaban
- Mariana Jinga
- Florentina Ionita‑Radu
- Ana Caruntu
- Carmen Fierbinteanu‑Braticevici
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Affiliations: 5th Clinical Department, Gastroenterology and Internal Medicine Discipline, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Research, ‘Carol Davila’ University Central Emergency Military Hospital, 010825 Bucharest, Romania, Department of Gastroenterology, ‘Carol Davila’ University Central Emergency Military Hospital, 010825 Bucharest, Romania, Department of Maxillofacial Surgery, ‘Carol Davila’ University Central Emergency Military Hospital, 010825 Bucharest, Romania
Article Number: 604
|
Published online on: April 14, 2021

https://doi.org/10.3892/etm.2021.10036
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Abstract

This prospective study aimed to determine the manometric pattern and the prevalence of esophageal dysmotility in 79 morbidly obese patients selected for laparoscopic sleeve gastrectomy. After clinical evaluation and upper gastrointestinal endoscopy, high‑resolution esophageal manometry was performed. The esophageal peristalsis, lower esophageal sphincter (LES) basal pressure, and LES relaxation were evaluated. Demographic data showed a predominance of females (55.70%) and both females and males were in the 5th decade of life. In addition, approximately 3/4 of the patients (78.48%) were from the urban zone. The mean body mass index of the patients was 46.40±6.0069 kg/m2, with a maximum of 61 kg/m². The LES basal pressure was normal in 59.49% of the patients, with a mean value of 31.40±18.43 mmHg. LES basal hypertonia was observed in 26.58%, and LES hypotonia in 13.93% of patients; 46.84% (37 patients) had abnormal manometric findings: 24.05% (19 patients) had EGJ outflow obstruction, 12.66% (10 patients) ineffective esophageal motility, 3.8% (3 patients) distal esophageal spasm, 3.8% (3 patients) Jackhammer esophagus, 2 cases were suggestive for type 2 achalasia but in asymptomatic patients. Ineffective esophageal motility was not associated with diabetes mellitus type 2 or erosive esophagitis according to our data. Hiatal hernia (HH) was manometrically diagnosed in 23 patients (29.11%). Preoperative high‑resolution esophageal manometry in obese patients demonstrated a high prevalence of motility disorders, but in asymptomatic patients, thus in the future, we require more studies and larger cohorts to better appreciate the clinical impact.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Manometric changes of the esophagus in morbidly obese patients

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