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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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June-2021 Volume 21 Issue 6

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Article Open Access

Influence of fine particulate matter and its pure particulate fractions on pulmonary immune cells and cytokines in mice

Zhouguang Jiao, Zhanbo Wen, Wenhui Yang, Lingfei Hu, Jinsong Li
Article Number: 662
Published online on: 21 April 2021

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Article Open Access

Apoptosis in HUVECs induced by microRNA‑616‑3p via X‑linked inhibitor of apoptosis protein targeting

Hua Chen, Xi Liu, Yun Wu, Xiayin Wu, Xiaoli Wen, Yanan Lu, Xingsheng Zhao
Article Number: 661
Published online on: 21 April 2021

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Article Open Access

Transcriptomic analysis and competing endogenous RNA network in the human endometrium between proliferative and mid‑secretory phases

Seong-Lan Yu, Tae-Hyun Kim, Young-Hyun Han, Yujin Kang, Da-Un Jeong, Dong Chul Lee, Jaeku Kang, Seok-Rae Park
Article Number: 660
Published online on: 20 April 2021

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Article

MicroRNA‑219a‑2‑3p modulates the proliferation of thyroid cancer cells via the HPSE/cyclin D1 pathway

Chuanjia Yang, Siyang Zhang, Xiaoying Chang, Yonglian Huang, Dongxu Cui, Zhen Liu
Article Number: 659
Published online on: 20 April 2021

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Review Open Access

Facing coronavirus disease 2019: What do we know so far? (Review)

Qie Guo, Wen Xu, Pan-Feng Wang, Hong-Yan Ji, Xiao-Lei Zhang, Kai Wang, Jing Li
Article Number: 658
Published online on: 20 April 2021

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Article Open Access

Association of obstructive sleep apnea/hypopnea syndrome with glaucomatous optic neuropathy and ocular blood flow

Georgios Dalianis, Alexandra Trivli, Aliki Limnopoulou, Andreas Stavrakis, Chryssa Terzidou, Efstathios T. Detorakis, Vassilios Kozobolis, Georgios Labiris
Article Number: 657
Published online on: 20 April 2021

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Review Open Access

Regulatory mechanism of calcium/calmodulin‑dependent protein kinase II in the occurrence and development of ventricular arrhythmia (Review)

Kexin Ma, Guoping Ma, Zijing Guo, Gang Liu, Wenjie Liang
Article Number: 656
Published online on: 20 April 2021

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Article Open Access

Effect of Porphyromonas gingivalis lipopolysaccharide on calcification of human umbilical artery smooth muscle cells co-cultured with human periodontal ligament cells

Jing Li, Jing Deng, Shuxian Shang, Guirong Liu, Wenbin Song, Pei Sun, Wenjing Jiang, Keqing Pan
Article Number: 655
Published online on: 20 April 2021

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Article Open Access

Apatinib inhibits gastric carcinoma development by regulating the expression levels of IL‑17 via the Bax/Bcl‑2 signaling pathway

Tianxi Wang, Jun Zhang, Lihong Cui
Article Number: 654
Published online on: 19 April 2021

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Retraction Open Access

[Retracted] Anticancer activity of bergenin against cervical cancer cells involves apoptosis, cell cycle arrest, inhibition of cell migration and the STAT3 signalling pathway

Xingyuan Shi, Manman Xu, Kai Luo, Wenjin Huang, Hongwei Yu, Tongchong Zhou
Article Number: 653
Published online on: 19 April 2021

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Article Open Access

miR‑221‑3p and miR‑222‑3p regulate the SOCS3/STAT3 signaling pathway to downregulate the expression of NIS and reduce radiosensitivity in thyroid cancer

Ting Ye, Lili Zhong, Xuemei Ye, Jie Liu, Linfa Li, Heqing Yi
Article Number: 652
Published online on: 19 April 2021

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Article Open Access

Protein kinase N1 promotes proliferation and invasion of liver cancer

Xia Wang, Yansong Ge, Mingqi Shi, Hanhan Dai, Wei Liu, Peiyuan Wang
Article Number: 651
Published online on: 19 April 2021

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Review Open Access

Changes in peri‑ocular anatomy and physiology in pseudoexfoliation syndrome (Review)

Efstathios T. Detorakis, Georgios Bontzos, Eleni E. Drakonaki, Demetrios A. Spandidos
Article Number: 650
Published online on: 19 April 2021

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Article

Efficiency of antiviral treatment in COVID‑19

Nicoleta Negrut, Adriana Codrean, Ioana Hodisan, Simona Bungau, Delia Mirela Tit, Ruxandra Marin, Tapan Behl, Florin Banica, Camelia C. Diaconu, Delia Carmen Nistor‑Cseppento
Article Number: 648
Published online on: 19 April 2021

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Article Open Access

Sinomenine activation of Nrf2 signaling prevents inflammation and cerebral injury in a mouse model of ischemic stroke

Fangfang Bi, Yiyong Zhang, Wenbo Liu, Keliang Xie
Article Number: 647
Published online on: 18 April 2021

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Article Open Access

Hypoxia‑inducible factor‑1α regulates PI3K/AKT signaling through microRNA‑32‑5p/PTEN and affects nucleus pulposus cell proliferation and apoptosis

Daolu Zhan, Mingxia Lin, Jian Chen, Wentao Cai, Jian Liu, Yehan Fang, Yibo Li, Bin Wu, Guangji Wang
Article Number: 646
Published online on: 18 April 2021

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Article Open Access

lncRNA NORAD promotes the progression of osteosarcoma via targeting of miR‑155‑5p

Ye Wang, Bin Zhou, Liping Yan, Jianhui Wu, Zhijie Xing, Shaochun Zhang, Fusheng Xiang
Article Number: 645
Published online on: 18 April 2021

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Article Open Access

Upregulation of long non‑coding RNA MYU promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells

Shudong Gu, Li Qian, Yan Liu, Jiefei Miao, Hong Shen, Shu Zhang, Guoxin Mao
Article Number: 644
Published online on: 18 April 2021

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Article Open Access

Diagnostic accuracy of ultrasonography for the prenatal diagnosis of esophageal atresia and tracheoesophageal fistula

Cong Wang, Xiaofei Ning, Yangcan Duan, Zhonglu Zhang, Shaochun Wang
Article Number: 643
Published online on: 18 April 2021

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Article Open Access

Life‑threatening complications of hyperemesis gravidarum

Stefan L. Popa, Maria Barsan, Alexandra Caziuc, Cristina Pop, Lucian Muresan, Luminita Celia Popa, Lacramioara Perju‑Dumbrava
Article Number: 642
Published online on: 16 April 2021

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Article

Clinical and diagnostic value of the combination of lymphocyte count and creatine kinase in the detection of coronavirus 2019

Yanqing Du, Xiang Wang, Zhonghua Qin, Lixia Zhang
Article Number: 641
Published online on: 16 April 2021

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Article Open Access

Interleukin‑1 induces receptor activator of nuclear factor‑κB ligand‑independent osteoclast differentiation in RAW264.7 cells

Rongdong Liao, Zhuoxi Feng, Wei Li, Rubing Liu, Xinrou Xu, Shun Yao, Jing Tian
Article Number: 640
Published online on: 16 April 2021

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Review Open Access

Effects of leukocyte‑ and platelet‑rich plasma on tendon disorders based on in vitro and in vivo studies (Review)

Xueli Liu, Rong Zhang, Bin Zhu, Yujie Li, Xinyue Liu, Sheng Guo, Chenglong Wang, Dingxuan Wang, Sen Li
Article Number: 639
Published online on: 16 April 2021

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Article Open Access

Gallic acid suppresses colon cancer proliferation by inhibiting SRC and EGFR phosphorylation

Xiaoming Lin, Guangfei Wang, Ping Liu, Lei Han, Tong Wang, Kaili Chen, Yonglin Gao
Article Number: 638
Published online on: 16 April 2021

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Article Open Access

Secreted frizzled‑related protein 4 promotes brown adipocyte differentiation

Hua Guan, Huiyuan Zheng, Jin Zhang, Aoqi Xiang, Yongxin Li, Huadong Zheng, Lixian Xu, Enqi Liu, Qi Yu
Article Number: 637
Published online on: 15 April 2021

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Article Open Access

Salidroside overcomes dexamethasone resistance in T‑acute lymphoblastic leukemia cells

Ya-Na Niu, Yan Zeng, Fang-Fang Zhong, Si-Li Long, Dan-Wei Ren, Xiang Qin, Wen-Jun Liu
Article Number: 636
Published online on: 15 April 2021

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Article Open Access

Microarray analysis of the time‑dependent expression profiles of long non‑coding RNAs in the progression of vein graft stenotic disease

Jiayu Shen, Hongwei Zhang, Chen Lu, Jun Gu, Yu Zhang, Jia Hu
Article Number: 635
Published online on: 15 April 2021

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Article Open Access

Circular RNA expression profiles in the plasma of patients with infantile hemangioma determined using microarray analysis

Zhiyu Li, Yimeng Chai, Zifu Zhou, Xueqing Li, Jianhai Bi, Ran Huo
Article Number: 634
Published online on: 15 April 2021

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Article Open Access

Differential proteomic analysis of tibial subchondral bone from male and female guinea pigs with spontaneous osteoarthritis

Ying Wang, Chengai Wu, Jianfeng Tao, Danhui Zhao, Xu Jiang, Wei Tian
Article Number: 633
Published online on: 15 April 2021

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Article Open Access

Subacute toxicological evaluation of AT‑533 and AT‑533 gel in Sprague‑Dawley rats

Yanting Wu, Xiaowei Song, Shurong Qin, Pengxiao Chen, Lianzhou Huang, Qiaoli Wang, Tianhao Shan, Feng Liang, Xiaofeng Liao, Qiuying Liu, Yunsheng Huang, Yifei Wang
Article Number: 632
Published online on: 15 April 2021

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Article Open Access

MicroRNA‑325 inhibits the proliferation and induces the apoptosis of T cell acute lymphoblastic leukemia cells in a BAG2‑dependent manner

Fengyu Wang, Fengli Wang, Shengyu Zhang, Xiaogang Xu
Article Number: 631
Published online on: 15 April 2021

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Article Open Access

miR‑1184 regulates inflammatory responses and cell apoptosis by targeting TRADD in an LPS‑induced cell model of sepsis

Ping Ling, Rong Tang, Huazhu Wang, Xiuqin Deng, Jianli Chen
Article Number: 630
Published online on: 15 April 2021

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Article Open Access

Thioredoxin relieves lipopolysaccharide‑induced acute kidney injury in mice by reducing inflammation, oxidative stress and apoptosis

Jingjing Wang, Wenjuan Zhang, Guoyuan Lu
Article Number: 629
Published online on: 15 April 2021

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Article Open Access

Simvastatin intervention mitigates hypercholesterolemia‑induced alveolar bone resorption in rats

Xiaoli Gao, Jianhua Zhou, Yuanyuan Bian, Shengyun Huang, Dongsheng Zhang
Article Number: 628
Published online on: 15 April 2021

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Article Open Access

Interleukin-12 exacerbates symptoms in an MRL/MpJ-Faslpr mouse model of systemic lupus erythematosus

Ling Li, Xiaojun Sun, Sisi Wu, Xin Yuan, Bingxin Liu, Xueping Zhou
Article Number: 627
Published online on: 15 April 2021

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Article Open Access

Effects of hypothermia on inflammatory cytokine expression in rat liver following asphyxial cardiac arrest

Yoonsoo Park, Ji Hyeon Ahn, Jeong Hwi Cho, Hyun-Jin Tae, Tae-Kyeong Lee, Bora Kim, Jae-Chul Lee, Joon Ha Park, Myoung Cheol Shin, Taek Geun Ohk, Jun Hwi Cho, Moo-Ho Won
Article Number: 626
Published online on: 15 April 2021

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Article Open Access

NICE‑3‑knockdown induces cell cycle arrest and autophagy in lung adenocarcinoma cells via the AKT/mTORC1 signaling pathway

Longxia Du, Youru Wu, Xiaodan Han, Chen Wang, Aili Li, Guojin Huang
Article Number: 625
Published online on: 15 April 2021

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Review

Chemical hemorrhagic cystitis: Diagnostic and therapeutic pitfalls (Review)

Razvan-Cosmin Petca, Razvan-Ionut Popescu, Cristian Toma, Mihai Cristian Dumitrascu, Aida Petca, Florica Sandru, Calin Bogdan Chibelean
Article Number: 624
Published online on: 14 April 2021

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Article Open Access

Effect of media distraction (audio‑visual and music) for pain and anxiety control in patients undergoing shock‑wave lithotripsy: A systematic review and meta‑analysis

Weihua Hu, Ke Yang, Li Zhang, Xu Lu
Article Number: 623
Published online on: 14 April 2021

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Article Open Access

miR‑491‑5p inhibits the proliferation and migration of A549 cells by FOXP4

Fuyong Wu, Aiping Ji, Zhenkun Zhang, Jinfang Li, Penglong Li
Article Number: 622
Published online on: 14 April 2021

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Article Open Access

Joint line plate fixation for tibial plateau fractures caused by hyperextension varus

Yu-Cheng Huang, Jing Jiao, Wen-Jun Cheng, Fei Xiao, Wei Zuo, Jun-Wen Wang
Article Number: 621
Published online on: 14 April 2021

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Article Open Access

Transforming growth factor‑β1‑induced podocyte injury is associated with increased microRNA‑155 expression, enhanced inflammatory responses and MAPK pathway activation

Xintong Zheng, Qiuhong Zhong, Xu Lin, Xianjun Gu, Xiaoyan Ling, Zhao Liang, Qing Qin, Xiuri Du
Article Number: 620
Published online on: 14 April 2021

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Article Open Access

Polycomb group protein Bmi1 is required for the neuronal differentiation of mouse induced pluripotent stem cells

Wei Shan, Liping Zhou, Lizhen Liu, Deju Lin, Qin Yu
Article Number: 619
Published online on: 14 April 2021

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Article Open Access

Total flavonoids of Rhizoma Drynariae combined with calcium attenuate osteoporosis by reducing reactive oxygen species generation

Panyun Mu, Yimei Hu, Xu Ma, Jingru Shi, Zhendong Zhong, Lingyuan Huang
Article Number: 618
Published online on: 14 April 2021

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Article

Changes in bone mineral density, 25‑hydroxyvitamin D3 and inflammatory factors in patients with hyperthyroidism

Yali Zhou, Xixia Wang, Maoyuan Xin, Haiting Zhuang
Article Number: 617
Published online on: 14 April 2021

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Article

ΜicroRNA‑122 protects against ischemic stroke by targeting Maf1

Mengmeng Wang, Xiaoman Liu, Yu Wu, Yi Wang, Jiahui Cui, Jing Sun, Ying Bai, Ming-Fei Lang
Article Number: 616
Published online on: 14 April 2021

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Article Open Access

Exogenous transforming growth factor‑β1 prevents the inflow of fluoride to ameleoblasts through regulation of voltage‑gated chloride channels 5 and 7

Mei Ji, Xuejing Duan, Xiaohui Han, Jing Sun, Dongsheng Zhang
Article Number: 615
Published online on: 14 April 2021

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Article Open Access

Novel ARID1B variant inherited from somatogonadal mosaic mother in siblings with Coffin‑Siris syndrome 1

Zhong Min, Cheng Qian, Dai Ying
Article Number: 614
Published online on: 14 April 2021

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Article Open Access

PHLDA3 inhibition attenuates endoplasmic reticulum stress‑induced apoptosis in myocardial hypoxia/reoxygenation injury by activating the PI3K/AKT signaling pathway

Kai Liu, Ying Chen, Fen Ai, Yun-Qian Li, Kun Zhang, Wei-Tong Zhang
Article Number: 613
Published online on: 14 April 2021

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Article

Prevalence of GJB2 gene mutations correlated to presence of clinical and environmental risk factors in the etiology of congenital sensorineural hearing loss of the Romanian population

Alexandra Neagu, Adela-Ioana Mocanu, Alexandru  Bonciu, Gabriella Coadă, Horia Mocanu
Article Number: 612
Published online on: 14 April 2021

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Article

Ultrasonography used in the diagnosis of chronic rhinosinusitis: From experimental imaging to clinical practice

Adriana Neagos, Mihai Dumitru, Daniela Vrinceanu, Adrian  Costache, Andreea Nicoleta Marinescu, Romica Cergan
Article Number: 611
Published online on: 14 April 2021

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Review Open Access

Muscular dystrophy: Experimental animal models and therapeutic approaches (Review)

Gisela Gaina, Alexandra Popa (Gruianu)
Article Number: 610
Published online on: 14 April 2021

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Review

Respiratory allergies: Salicaceae sensitization (Review)

Adrian Costache, Ovidiu Nicolae Berghi, Romica Cergan, Mihai Dumitru, Adriana Neagos, Liliana Gabriela Popa, Calin Giurcaneanu, Daniela Vrinceanu
Article Number: 609
Published online on: 14 April 2021

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Article Open Access

Crosstalk between vitamin D axis, inflammation and host immunity mechanisms: A prospective study

Andreea-Daniela Meca, Simona Ștefănescu, Maria Bogdan, Adina Turcu‑Stiolică, Floarea Mimi Nițu, Marius Matei, Ramona Cioboată, Ana Maria Bugă, Cătălina-Gabriela Pisoschi
Article Number: 608
Published online on: 14 April 2021

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Article Open Access

Incidence of thyroid carcinomas in an extended retrospective study of 526 autopsies

Iuliana Sobaru Mohorea, Bogdan Socea, Dragoş Şerban, Zenaida Ceausu, Adrian Tulin, Violeta Melinte, Mihai Ceausu
Article Number: 607
Published online on: 14 April 2021

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Article Open Access

Fetal cardiac evaluation in HIV‑positive women under HAART therapy in a Romanian hospital

Alexandra Ursache, Alexandra Maria Tibeica, Alexandru Luca, Mircea Onofriescu, Daniela Roxana Matasariu, Dragos Nemescu
Article Number: 606
Published online on: 14 April 2021

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Article Open Access

Predictors of the response to nivolumab immunotherapy in the second or subsequent lines for metastatic non‑small cell lung cancers

Sorin Săftescu, Șerban Negru, Simona Volovăț, Dorel Popovici, Vlad Chercota, Simona Stanca, Horea Feier, Daniel  Malita, Radu Dragomir, Constantin Volovăț
Article Number: 605
Published online on: 14 April 2021

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Article

Manometric changes of the esophagus in morbidly obese patients

Andrada L. Popescu, Raluca S. Costache, Daniel O. Costache, Vasile D. Balaban, Mariana Jinga, Florentina Ionita‑Radu, Ana Caruntu, Carmen Fierbinteanu‑Braticevici
Article Number: 604
Published online on: 14 April 2021

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Case Report

Catheter‑related giant right atrial thrombosis mimicking a myxoma: A case report

Ovidiu Stiru, Razvan Dragulescu, Roxana Carmen Geana, Andreea Chibulcutean, Laura Raducu, Adrian Tulin, Andra Balcangiu Stroescu, Camelia Diaconu, Cornel Savu, Nicolae Bacalbasa, Irina Balescu, Vlad Anton Iliescu
Article Number: 603
Published online on: 14 April 2021

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Article Open Access

Interrelation of inflammation and oxidative stress in liver cirrhosis

Mihnea Marian Pomacu, Maria Diana Trașcă, Vlad Pădureanu, Ana Maria Bugă, Ana Marina Andrei, Elena Camelia Stănciulescu, Ileana Monica Baniță, Dumitru Rădulescu, Cătălina Gabriela Pisoschi
Article Number: 602
Published online on: 14 April 2021

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Retraction Open Access

[Retracted] Anticancer activity of 23,24-dihydrocucurbitacin B against the HeLa human cervical cell line is due to apoptosis and G2/M cell cycle arrest

Jun-Xiao Zhang, Wei-Tan Hong, Chun-Yan Hu, Wei-Qiang Wang, Guang-Hua Chu, Li-Hui Wei, Liu Chen
Article Number: 601
Published online on: 12 April 2021

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Article Open Access

Role of Notch, IL‑1 and leptin expression in colorectal cancer

Nilufer Erkasap, Rumeysa Ozyurt, Mete Ozkurt, Serdar Erkasap, Fatih Yasar, Enver Ihtiyar, Evrim Ciftci, Funda Canaz, Ertugrul Colak
Article Number: 600
Published online on: 11 April 2021

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Intra‑articular injections of platelet‑rich plasma vs. hyaluronic acid in patients with knee osteoarthritis: Preliminary follow‑up results at 6‑months

Ming Li, Zheyu Huang, Shicheng Wang, Zhenglin Di, Junhui Zhang, Hua Liu
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Dl‑butylphthalide inhibits rotenone‑induced oxidative stress in microglia via regulation of the Keap1/Nrf2/HO‑1 signaling pathway

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Microcirculatory disturbance in acute liver injury

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A minimum 8-year follow-up comparative study of decompression and coflex stabilization with decompression and fusion

Xiaoqing Zheng, Zhida Chen, Honglong Yu, Jianxiong Zhuang, Hui Yu, Yunbing Chang
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Interferon‑τ regulates the expression and function of bovine leukocyte antigen by downregulating bta‑miR‑204

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IGF2BP2 knockdown inhibits LPS‑induced pyroptosis in BEAS‑2B cells by targeting caspase 4, a crucial molecule of the non‑canonical pyroptosis pathway

Jing Wang, Xiaoli Yuan, Ning Ding
Article Number: 593
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Downregulation of miR‑588 is associated with tumor progression and unfavorable prognosis in patients with osteosarcoma

Tao Yu, Shuang Liang, Tianhong Ma, Weidong Song
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Published online on: 08 April 2021

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Comparison of anti‑inflammatory effects of Mecasin and its constituents on lipopolysaccharide‑stimulated BV2 cells

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Paeoniflorin suppresses allergic and inflammatory responses by promoting autophagy in rats with urticaria

Jing Guo, Li Peng, Jinhao Zeng, Meiheng Zhang, Feng Xu, Xiaotong Zhang, Qin Wei
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Analysis of crucial genes, pathways and construction of the molecular regulatory networks in vascular smooth muscle cell calcification

Xiaomin Wei, Yiming Su, Qiyi Li, Zhiyong Zheng, Peiyong Hou
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Hongfang Li, Yunyan Tang, Weipeng Wei, Chengchen Yin, Fushan Tang
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Resveratrol sensitizes A549 cells to irradiation damage via suppression of store‑operated calcium entry with Orai1 and STIM1 downregulation

Wu Lele, Lv Lei, Qian Liting
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Ginkgolide B alleviates the inflammatory response and attenuates the activation of LPS‑induced BV2 cells in vitro and in vivo

Miaoxuan Sun, Yi Sheng, Yanyan Zhu
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miR‑125b/NRF2/HO‑1 axis is involved in protection against oxidative stress of cystic fibrosis: A pilot study

Maria Pelullo, Daniela Savi, Serena Quattrucci, Giuseppe Cimino, Antonio Pizzuti, Isabella Screpanti, Claudio Talora, Samantha Cialfi
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Published online on: 02 April 2021

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Diclofenac impairs the proliferation and glucose metabolism of triple‑negative breast cancer cells by targeting the c‑Myc pathway

Lihui Yang, Jiachen Li, Yongzhuo Li, Yongli Zhou, Ziqian Wang, Dahao Zhang, Jinlu Liu, Xiaodong Zhang
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MicroRNA‑451a plays a role in polycystic ovary syndrome by regulating ovarian granulosa cell proliferation and apoptosis

Tianjin Yang, Lie Wang, Yun Zhang, Jindan Zheng, Lili Liu
Article Number: 583
Published online on: 02 April 2021

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Changes of type II collagenase biomarkers on IL‑1β‑induced rat articular chondrocytes Corrigendum in /10.3892/etm.2023.12040

Xiangying Ma, Zhiheng Zhang, Meilun Shen, Yuanqiang Ma, Rouqian Li, Xiaodi Jin, Li Gao, Zhi Wang
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Metformin prevents PFKFB3‑related aerobic glycolysis from enhancing collagen synthesis in lung fibroblasts by regulating AMPK/mTOR pathway

Ci-Jun Tang, Ji Xu, Hai-Yan Ye, Xue-Bin Wang
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Irisin enhances osteogenic differentiation of mouse MC3T3‑E1 cells via upregulating osteogenic genes

Jian Yang, Kai Yu, Dongmei Liu, Jie Yang, Li Tan, Dianying Zhang
Article Number: 580
Published online on: 31 March 2021

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Transcriptomic analysis identifies upregulation of secreted phosphoprotein 1 in silicotic rats

Wenchen Cai, Bonan Zhang, Tian Li, Fuyu Jin, Yaqian Li, Hong Xu, Fang Yang
Article Number: 579
Published online on: 31 March 2021

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Metformin attenuates diabetic renal injury via the AMPK‑autophagy axis Retraction in /10.3892/etm.2025.12957

Tingli Sun, Jizhang Liu, Changying Xie, Jun Yang, Lijie Zhao, Jingbo Yang
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Published online on: 31 March 2021

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Jing-Jing Zha, Yi Tang, Ya-Lan Wang
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Published online on: 31 March 2021

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Ginkgo biloba delays light‑induced photoreceptor degeneration through antioxidant and antiapoptotic properties

Maryam Chudhary, Chenghong Zhang, Shiyu Song, Xiang Ren, Li Kong
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Published online on: 31 March 2021

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Massive efflux of adenosine triphosphate into the extracellular space immediately after experimental traumatic brain injury

Nobuhiro Moro, Sima S. Ghavim, Richard L. Sutton
Article Number: 575
Published online on: 31 March 2021

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MicroRNA‑361‑5p induces hepatocellular carcinoma cell apoptosis and enhances drug sensitivity by targeting MAP3K9

Qingbo Ren, Xiangmei Xiao, Xiaoqian Leng, Qi Zhang, Xue Zhou, Ziyuan Ren, Hang Xiao
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Published online on: 31 March 2021

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The herbal agent plantamajoside, exerts a potential inhibitory effect on the development of hepatocellular carcinoma

Shu Luo, Xing Jiang, Gang Yin, Yajun Liu, Zhou Liu, Linglian Meng, Jian Wu, Haoxin Wu
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Published online on: 31 March 2021

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Paeoniflorin protects PC12 cells from oxygen-glucose deprivation/reoxygenation-induced injury via activating JAK2/STAT3 signaling

Zhuo Zhang, Weimin Yang
Article Number: 572
Published online on: 29 March 2021

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Transcriptome analysis reveals key pathways that vary in patients with paroxysmal and persistent atrial fibrillation

Haoliang Sun, Yongfeng Shao
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Published online on: 29 March 2021

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Clinical significance of serum transforming growth factor‑β1 and procollagen type I N‑propeptide in post‑tuberculosis tracheobronchial stenosis

Yongchang Wu, Yishi Li, Yang Bai, Jinyue Jiang, Xiaohui Wang, Yi Chen, Xin Wang, Guichuan Huang, Yiling Gan, You Li, Shuliang Guo
Article Number: 570
Published online on: 29 March 2021

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MicroRNA‑301a‑3p increases oxidative stress, inflammation and apoptosis in ox‑LDL‑induced HUVECs by targeting KLF7

Huiqiong Jiang, Jiaren Lv
Article Number: 569
Published online on: 29 March 2021

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TNF‑α promotes insulin resistance in obstructive sleep apnea‑hypopnea syndrome

Lin Zhao, Yang Liu, Xiangrong Wang
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Published online on: 29 March 2021

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Infection‑provoked psoriasis: Induced or aggravated (Review)

Yan Teng, Wenqing Xie, Xiaohua Tao, Na Liu, Yong  Yu, Youming Huang, Danfeng Xu, Yibin Fan
Article Number: 567
Published online on: 29 March 2021

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Anticancer activity of repurposed hemostatic agent desmopressin on AVPR2‑expressing human osteosarcoma

Natasha Tatiana Sobol, Luisina María Solernó, Brady Beltrán, Liliana Vásquez, Giselle Vanina Ripoll, Juan Garona, Daniel Fernando Alonso
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Published online on: 26 March 2021

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Butylphthalide inhibits nerve cell apoptosis in cerebral infarction rats via the JNK/p38 MAPK signaling pathway

Xiangye Bu, Wenqing Xia, Xiaonan Wang, Shan Lu, Yue Gao
Article Number: 565
Published online on: 26 March 2021

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C-C motif chemokine ligand 2/C-C receptor 2 is associated with glioma recurrence and poor survival

Qiuan Yang, Junpeng Zhang, Xin Zhang, Lifeng Miao, Wei Zhang, Zheng Jiang, Wei Zhou
Article Number: 564
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Alliin inhibits adipocyte differentiation by downregulating Akt expression: Implications for metabolic disease

Ni Li, Kai Chen, Hongwei Dong, Jing Yang, Michiko Yoshizawa, Hideaki Kagami, Xianqi Li
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Functional genetic variants in the 3'UTR of PTPRD associated with the risk of gestational diabetes mellitus

Yan Kang, Huamin Huang, Haipeng Li, Wenping Sun, Cuicui Zhang
Article Number: 562
Published online on: 26 March 2021

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Differences between myeloperoxidase‑antineutrophil cytoplasmic autoantibody (ANCA) and proteinase 3‑ANCA associated vasculitis: A retrospective study from a single center in China

Ting Wu, Chanjuan Shen, Yong Zhong, Joshua D. Ooi, Ya-Ou Zhou, Jin-Biao Chen, Ting Meng, Zhou Xiao, Wei Lin, Xiang Ao, Xiangcheng Xiao, Qiaoling Zhou, Ping Xiao
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Adropin inhibits the phenotypic modulation and proliferation of vascular smooth muscle cells during neointimal hyperplasia by activating the AMPK/ACC signaling pathway

Li Wang, Liang-Ping Zhao, Yu-Qi Chen, Xian-Song Chang, Hui Xiong, Dai-Min Zhang, Wei-Ting Xu, Jian-Chang Chen
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Published online on: 26 March 2021

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Long non‑coding RNA ADAMTS9‑AS2 inhibits liver cancer cell proliferation, migration and invasion

Hanjun Li, Hu Huang, Sha Li, Hongliang Mei, Tingjia Cao, Qiping Lu
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Article

Circulating IL‑37 levels are elevated in patients with hypertension

Jing Ye, Yuan Wang, Zhen Wang, Yingzhong Lin, Ling Liu, Qi Zhou, Menglong Wang, Yao Xu, Di Ye, Jishou Zhang, Jun Wan, Qingwei Ji
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Published online on: 26 March 2021

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DJ‑1 affects oxidative stress and pyroptosis in hippocampal neurons of Alzheimer's disease mouse model by regulating the Nrf2 pathway

Lin Cheng, Wei Zhang
Article Number: 557
Published online on: 26 March 2021

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Oxymatrine pretreatment protects H9c2 cardiomyocytes from hypoxia/reoxygenation injury by modulating the PI3K/Akt pathway

Zhongbai Zhang, Xueting Qin, Zhenghui Wang, Yanchun Li, Fei Chen, Rundu Chen, Chuang Li, Wencheng Zhang, Mei Zhang
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Published online on: 26 March 2021

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The role of miRNA, lncRNA and circRNA in the development of intervertebral disk degeneration (Review)

Jian Jiang, Yuefeng Sun, Gaoran Xu, Hong Wang, Ling Wang
Article Number: 555
Published online on: 26 March 2021

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Expression levels of VEGF‑C and VEGFR‑3 in renal cell carcinoma and their association with lymph node metastasis

Xiuming Li, Dianbin Song, Hui Liu, Zhiyong Wang, Guang Ma, Man Yu, Yong Zhang, Yu Zeng
Article Number: 554
Published online on: 26 March 2021

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Effects of Shenfu Qiangxin Drink on H2O2‑induced oxidative stress, inflammation and apoptosis in neonatal rat cardiomyocytes and possible underlying mechanisms

Sujie Zhang, Yiyan Zhang, Xindong Wang, Lixing Wu, Jianping Shen, Minglin Gu, Zhuyuan Fang
Article Number: 553
Published online on: 26 March 2021

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Effect of ginsenoside‑Rg1 on experimental Parkinson's disease: A systematic review and meta‑analysis of animal studies

Yi-Bo He, Yong-Lin Liu, Zheng-Dong Yang, Jia-Hong Lu, Yao Song, Yan-Ming Guan, Yi-Min Chen
Article Number: 552
Published online on: 25 March 2021

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Ultrasound‑targeted microbubble destruction enhances the anti‑tumor action of miR‑4284 inhibitor in non‑small cell lung cancer cells

Peng Tian, Yanzhen Wang, Wenyan Du
Article Number: 551
Published online on: 25 March 2021

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Role of STAT1 in the resistance of HBV to IFN‑α

Bingfa Xu, Bo Tang, Jiajia Wei
Article Number: 550
Published online on: 24 March 2021

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MicroRNA‑363‑3p inhibits tumor cell proliferation and invasion in oral squamous cell carcinoma cell lines by targeting SSFA2

Liangming Zhu, Lei Zhang, Ying Tang, Fang Zhang, Chao Wan, Liang Xu, Ping Guo
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Curcumin relieves mice gastric emptying dysfunction induced by L‑arginine and atropine through interstitial cells of Cajal

Peng Lin, Baitao Li, Junli Ye, Fangfang Shang, Hui Zhao, Jing Xie, Xiaoling Yu
Article Number: 548
Published online on: 24 March 2021

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Arctigenin inhibits human breast cancer cell proliferation, migratory and invasive abilities and epithelial to mesenchymal transition by targeting 4EBP1

Wenfang Luo, Fei Wang, Hewei Luo, Hui Liu
Article Number: 547
Published online on: 24 March 2021

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Small molecules efficiently reprogram apical papilla stem cells into neuron‑like cells

Qixin Chen, Changyong Yuan, Shan Jiang, Boon Chin Heng, Ting Zou, Zhongshan Shen, Penglai Wang, Chengfei Zhang
Article Number: 546
Published online on: 24 March 2021

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[Retracted] MicroRNA differential expression spectrum and microRNA‑125a‑5p inhibition of laryngeal cancer cell proliferation

Xiang-Dong Yao, Ping Li, Ji-Sheng Wang
Article Number: 545
Published online on: 24 March 2021

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May-2026 Volume 31 Issue 5

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FCER1G: A multifunctional regulator in the immune microenvironment (Review)

Yuyu Zhang, Jinglan Wang, Wenting He, Tao Liu
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A nomogram for predicting recurrence‑free survival in patients with high‑risk GIST receiving adjuvant imatinib: A nationwide registry study

Chun-Nan Yeh, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh, Li-Yaun Bai, Jun-Te Hsu, I-Shu Chen, Li-Tzong Chen, Hui-Jen Tsai, The Taiwan Cooperative Oncology Group Gist Study Group
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Published online on: 24 March 2026

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[Retracted] MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 144
Published online on: 23 March 2026

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Risk factors for severe retinopathy of prematurity: A retrospective case‑control study

Qingmin Ma, Xi Lv, Jiangya Wang, Kejun Li, Wenwen Τang
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Published online on: 20 March 2026

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Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial

Dawei Wang, Jingya Dai, Shumei Li, Yaping Liu, Xiaofeng Xing, Lei Huang, Qijun Pang
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Maresin 1 activates autophagy through SIRT1/PPAR‑γ signaling to mitigate high glucose‑induced pyroptosis in human retinal pigment epithelial cells

Jun Zhang, Ding Zhao, Yuanqing Zhang, Haoxiang Sun, Zhipeng Yan, Haiyan Sun
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Advances in new ultrasound technologies in targeted prostate biopsy (Review)

Tingting Jin, Liying Wang, Shusen Zheng
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Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review)

Min Liu, Kui Su
Article Number: 139
Published online on: 19 March 2026

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Immunohistochemical evaluation of gastric‑type markers in primary extramammary Paget disease: Differential MUC5AC expression between in situ and invasive lesions

Naoto Kohno, Mitsuaki Ishida, Shizuka Ono, Yoshinobu Hirose
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Disrupted beginnings: Neurodevelopmental outcomes of COVID‑19 lockdowns in early childhood (Review)

Ioanna Giannopoulou, Vasiliki Efstathiou, Maria-Ioanna Stefanou, Panagiota Korkoliakou, James N. Tsoporis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 137
Published online on: 16 March 2026

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[Retracted] Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF‑κB and PI3K/AKT pathways

Ling Sun, Jing Zhang
Article Number: 136
Published online on: 16 March 2026

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Effects of fullerenol C60 on the liver, heart and brain tissues of streptozotocin‑induced diabetic rats with sepsis

Necmiye Şengel, Ömer Kubat, Laman Farajsoylu, Ahmet Çağri Büyükkasap, Muharrem Atli, Şaban Cem Sezen, Hasan Bostanci, Kürşat Dikmen, Işin Güneş, Fatma Er, Mustafa Kavutçu, Mustafa Arslan
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Long non‑coding RNA KCNQ1OT1 promotes ovarian cancer cell malignant characteristics by targeting the miR‑140‑5p/KLK10 axis

Renjie Duan, Zhenyu Tao, Shun Tao, Aichen Yang, Xu Yang, Changzheng Li, Xiaoxiang Zhu, Kexin Zhang, Zhuofu Li, Shanjun Tao
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Published online on: 11 March 2026

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Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
Published online on: 09 March 2026

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Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
Published online on: 09 March 2026

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Case Report Open Access

Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
Published online on: 06 March 2026

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Yajun Yao, Ge-Hong Dong, De-Cai Tian
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Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
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Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Case Report

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Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
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Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
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Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Article

Effects of spironolactone on cytotoxic damage in osteoblasts

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Article Number: 122
Published online on: 27 February 2026

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RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
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A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

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Case Report

A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
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Published online on: 26 February 2026

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Published online on: 26 February 2026

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June-2026 Volume 31 Issue 6

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Multi‑omics analysis of glutamine and fish collagen peptides in alleviating post‑antibiotic Streptococcus pneumoniae injury in feline lung cells

Huasong Bai, Tong Liu, Hengyan Wang, Hongchen Jin, Yunliang Li, Zhanzhong Wang
Article Number: 148
Published online on: 30 March 2026

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[Retracted] MicroRNA‑1236‑3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis

Tingting Meng, Shiman Shen, Cheng Li, Xuehua Liu
Article Number: 147
Published online on: 30 March 2026

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