|
1
|
Wang C, Xu J, Yang L, Xu Y, Zhang X, Bai
C, Kang J, Ran P, Shen H, Wen F, et al: Prevalence and risk factors
of chronic obstructive pulmonary disease in China [the China
pulmonary health (CPH) study]: A national cross-sectional study.
Lancet. 391:1706–1717. 2018.PubMed/NCBI View Article : Google Scholar
|
|
2
|
GBD 2015 Chronic Respiratory Disease
Collaborators. Global, regional, and national deaths, prevalence,
disability-adjusted life years, and years lived with disability for
chronic obstructive pulmonary disease and asthma, 1990-2015: A
systematic analysis for the global burden of disease study 2015.
Lancet Respir Med. 5:691–706. 2017.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Fang X, Wang X and Bai C: COPD in China:
The burden and importance of proper management. Chest. 139:920–929.
2011.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Neumeier A and Keith R: Clinical guideline
highlights for the hospitalist: The GOLD and NICE guidelines for
the management of COPD. J Hosp Med. 15:240–241. 2020.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Rabe KF, Hurd S, Anzueto A, Barnes PJ,
Buist SA, Calverley P, Fukuchi Y, Jenkins C, Rodriguez-Roisin R,
van Weel C, et al: Global strategy for the diagnosis, management,
and prevention of chronic obstructive pulmonary disease: GOLD
executive summary. Am J Respir Crit Care Med. 176:532–555.
2007.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Pauwels RA and Rabe KF: Burden and
clinical features of chronic obstructive pulmonary disease (COPD).
Lancet. 364:613–620. 2004.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Lopez AD and Mathers CD: Measuring the
global burden of disease and epidemiological transitions:
2002-2030. Ann Trop Med Parasitol. 100:481–499. 2006.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Ito K and Barnes PJ: COPD as a disease of
accelerated lung aging. Chest. 135:173–180. 2009.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Demedts IK, Demoor T, Bracke KR, Joos GF
and Brusselle GG: Role of apoptosis in the pathogenesis of COPD and
pulmonary emphysema. Respir Res. 7(53)2006.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Adcock IM, Tsaprouni L, Bhavsar P and Ito
K: Epigenetic regulation of airway inflammation. Curr Opin Immunol.
19:694–700. 2007.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Wan ES and Silverman EK: Genetics of COPD
and emphysema. Chest. 136:859–866. 2009.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Bartel DP: MicroRNAs: Genomics,
biogenesis, mechanism, and function. Cell. 116:281–297.
2004.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Hough KP, Chanda D, Duncan SR, Thannickal
VJ and Deshane JS: Exosomes in immunoregulation of chronic lung
diseases. Allergy. 72:534–544. 2017.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Murgoci AN, Duhamel M, Raffo-Romero A,
Mallah K, Aboulouard S, Lefebvre C, Kobeissy F, Fournier I, Zilkova
M, Maderova D, et al: Location of neonatal microglia drives small
extracellular vesicles content and biological functions in vitro. J
Extracell Vesicles. 9(1727637)2020.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Nana-Sinkam SP, Acunzo M, Croce CM and
Wang K: Extracellular vesicle biology in the pathogenesis of lung
disease. Am J Respir Crit Care Med. 196:1510–1518. 2017.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Stolzenburg LR and Harris A: The role of
microRNAs in chronic respiratory disease: Recent insights. Biol
Chem. 399:219–234. 2018.PubMed/NCBI View Article : Google Scholar
|
|
17
|
De Smet EG, Mestdagh P, Vandesompele J,
Brusselle GG and Bracke KR: Non-coding RNAs in the pathogenesis of
COPD. Thorax. 70:782–791. 2015.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Molina-Pinelo S, Pastor MD, Suarez R,
Romero-Romero B, González De la Peña M, Salinas A, García-Carbonero
R, De Miguel MJ, Rodríguez-Panadero F, Carnero A and Paz-Ares L:
MicroRNA clusters: Dysregulation in lung adenocarcinoma and COPD.
Eur Respir J. 43:1740–1749. 2014.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Robbins PD and Morelli AE: Regulation of
immune responses by extracellular vesicles. Nat Rev Immunol.
14:195–208. 2014.PubMed/NCBI View
Article : Google Scholar
|
|
20
|
Colombo M, Raposo G and Théry C:
Biogenesis, secretion, and intercellular interactions of exosomes
and other extracellular vesicles. Annu Rev Cell Dev Biol.
30:255–289. 2014.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Yoshioka Y, Konishi Y, Kosaka N, Katsuda
T, Kato T and Ochiya T: Comparative marker analysis of
extracellular vesicles in different human cancer types. J Extracell
Vesicles. 2:2013.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Mirzaei H, Sahebkar A, Jaafari MR,
Goodarzi M and Mirzaei HR: Diagnostic and therapeutic potential of
exosomes in cancer: The beginning of a new tale? J Cell Physiol.
232:3251–3260. 2017.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Saadatpour L, Fadaee E, Fadaei S, Nassiri
Mansour R, Mohammadi M, Mousavi SM, Goodarzi M, Verdi J and Mirzaei
H: Glioblastoma: Exosome and microRNA as novel diagnosis
biomarkers. Cancer Gene Ther. 23:415–418. 2016.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Sun L, Zhu W, Zhao P, Wang Q, Fan B, Zhu
Y, Lu Y, Chen Q, Zhang J and Zhang F: Long noncoding RNA UCA1 from
hypoxia-conditioned hMSC-derived exosomes: A novel molecular target
for cardioprotection through miR-873-5p/XIAP axis. Cell Death Dis.
11(696)2020.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Caby MP, Lankar D, Vincendeau-Scherrer C,
Raposo G and Bonnerot C: Exosomal-like vesicles are present in
human blood plasma. Int Immunol. 17:879–887. 2005.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Admyre C, Grunewald J, Thyberg J,
Gripenbäck S, Tornling G, Eklund A, Scheynius A and Gabrielsson S:
Exosomes with major histocompatibility complex class II and
co-stimulatory molecules are present in human BAL fluid. Eur Respir
J. 22:578–583. 2003.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Porro C, Lepore S, Trotta T, Castellani S,
Ratclif L, Battaglino A, Di Gioia S, Martínez MC, Conese M and
Maffione AB: Isolation and characterization of microparticles in
sputum from cystic fibrosis patients. Respir Res.
11(94)2010.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Salimian J, Mirzaei H, Moridikia A,
Harchegani AB, Sahebkar A and Salehi H: Chronic obstructive
pulmonary disease: MicroRNAs and exosomes as new diagnostic and
therapeutic biomarkers. J Res Med Sci. 23(27)2018.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Lener T, Gimona M, Aigner L, Börger V,
Buzas E, Camussi G, Chaput N, Chatterjee D, Court FA, Del Portillo
HA, et al: Applying extracellular vesicles based therapeutics in
clinical trials-an ISEV position paper. J Extracell Vesicles.
4(30087)2015.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Dang X, Qu X, Wang W, Liao C, Li Y, Zhang
X, Xu D, Baglole CJ, Shang D and Chang Y: Bioinformatic analysis of
microRNA and mRNA regulation in peripheral blood mononuclear cells
of patients with chronic obstructive pulmonary disease. Respir Res.
18(4)2017.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Kara M, Kirkil G and Kalemci S:
Differential expression of MicroRNAs in chronic obstructive
pulmonary disease. Adv Clin Exp Med. 25:21–26. 2016.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Wang L and Zhang L: Circulating exosomal
miRNA as diagnostic biomarkers of neurodegenerative diseases. Front
Mol Neurosci. 13(53)2020.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Albitar HAH and Iyer VN: Adherence to
global initiative for chronic obstructive lung disease guidelines
in the real world: Current understanding, barriers, and solutions.
Curr Opin Pulm Med. 26:149–154. 2020.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Sundar IK, Li D and Rahman I: Small
RNA-sequence analysis of plasma-derived extracellular vesicle
miRNAs in smokers and patients with chronic obstructive pulmonary
disease as circulating biomarkers. J Extracell Vesicles.
8(1684816)2019.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Théry C, Amigorena S, Raposo G and Clayton
A: Isolation and characterization of exosomes from cell culture
supernatants and biological fluids. Curr Protoc Cell Biol Chapter.
3(Unit 3 22)2006.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Mehdiani A, Maier A, Pinto A, Barth M,
Akhyari P and Lichtenberg A: An innovative method for exosome
quantification and size measurement. J Vis Exp: 50974, 2015.
|
|
37
|
Mortazavi A, Williams BA, McCue K,
Schaeffer L and Wold B: Mapping and quantifying mammalian
transcriptomes by RNA-Seq. Nat Methods. 5:621–628. 2008.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Robinson MD, McCarthy DJ and Smyth GK:
edgeR: A bioconductor package for differential expression analysis
of digital gene expression data. Bioinformatics. 26:139–140.
2010.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Parker VL, Cushen BF, Gavriil E, Marshall
B, Waite S, Pacey A and Heath PR: Comparison and optimisation of
microRNA extraction from the plasma of healthy pregnant women. Mol
Med Rep. 23(1)2021.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Xie C, Mao X, Huang J, Ding Y, Wu J, Dong
S, Kong L, Gao G, Li CY and Wei L: KOBAS 2.0: A web server for
annotation and identification of enriched pathways and diseases.
Nucleic Acids Res. 39 (Web Server Issue):W316–W322. 2011.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Shannon P, Markiel A, Ozier O, Baliga NS,
Wang JT, Ramage D, Amin N, Schwikowski B and Ideker T: Cytoscape: A
software environment for integrated models of biomolecular
interaction networks. Genome Res. 13:2498–2504. 2003.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Barabási AL and Oltvai ZN: Network
biology: Understanding the cell's functional organization. Nat Rev
Genet. 5:101–113. 2004.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Yáñez-MóM Siljander PR, Andreu Z, Zavec
AB, Borràs FE, Buzas EI, Buzas K, Casal E, Cappello F, Carvalho J,
et al: Biological properties of extracellular vesicles and their
physiological functions. J Extracell Vesicles.
4(27066)2015.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Fujita Y, Kosaka N, Araya J, Kuwano K and
Ochiya T: Extracellular vesicles in lung microenvironment and
pathogenesis. Trends Mol Med. 21:533–542. 2015.PubMed/NCBI View Article : Google Scholar
|
|
46
|
Wang C, Song C, Liu Q, Zhang R, Fu R, Wang
H, Yin D, Song W, Zhang H and Dou K: Gene expression analysis
suggests immunological changes of peripheral blood monocytes in the
progression of patients with coronary artery disease. Front Genet.
12(641117)2021.PubMed/NCBI View Article : Google Scholar
|
|
47
|
Hou Z, Qin X, Hu Y, Zhang X, Li G, Wu J,
Li J, Sha J, Chen J, Xia J, et al: Longterm exercise-derived
exosomal miR-342-5p: A novel exerkine for cardioprotection. Circ
Res. 124:1386–1400. 2019.PubMed/NCBI View Article : Google Scholar
|
|
48
|
Han Y, Chen J, Zhao X, Liang C, Wang Y,
Sun L, Jiang Z, Zhang Z, Yang R, Chen J, et al: MicroRNA expression
signatures of bladder cancer revealed by deep sequencing. PLoS One.
6(e18286)2011.PubMed/NCBI View Article : Google Scholar
|
|
49
|
Wang LP, Peng XY, Lv XQ, Liu L, Li XL, He
X, Lv F, Pan Y, Wang L, Liu KF and Zhang XM: High throughput
circRNAs sequencing profile of follicle fluid exosomes of
polycystic ovary syndrome patients. J Cell Physiol, Feb 18, 2019
(Epub ahead of print). doi: https://doi.org/10.1002/jcp.28201.
|
|
50
|
El-Mogy M, Lam B, Haj-Ahmad TA, McGowan S,
Yu D, Nosal L, Rghei N, Roberts P and Haj-Ahmad Y: Diversity and
signature of small RNA in different bodily fluids using next
generation sequencing. BMC Genomics. 19(408)2018.PubMed/NCBI View Article : Google Scholar
|
|
51
|
‘t Hoen PA, Ariyurek Y, Thygesen HH,
Vreugdenhil E, Vossen RH, de Menezes RX, Boer JM, van Ommen GJ and
den Dunnen JT: Deep sequencing-based expression analysis shows
major advances in robustness, resolution and inter-lab portability
over five microarray platforms. Nucleic Acids Res.
36(e141)2008.PubMed/NCBI View Article : Google Scholar
|
|
52
|
Ezzie ME, Crawford M, Cho JH, Orellana R,
Zhang S, Gelinas R, Batte K, Yu L, Nuovo G, Galas D, et al: Gene
expression networks in COPD: microRNA and mRNA regulation. Thorax.
67:122–131. 2012.PubMed/NCBI View Article : Google Scholar
|
|
53
|
Akbas F, Coskunpinar E, Aynaci E, Oltulu
YM and Yildiz P: Analysis of serum micro-RNAs as potential
biomarker in chronic obstructive pulmonary disease. Exp Lung Res.
38:286–294. 2012.PubMed/NCBI View Article : Google Scholar
|
|
54
|
Schembri F, Sridhar S, Perdomo C,
Gustafson AM, Zhang X, Ergun A, Lu J, Liu G, Zhang X, Bowers J, et
al: MicroRNAs as modulators of smoking-induced gene expression
changes in human airway epithelium. Proc Natl Acad Sci USA.
106:2319–2324. 2009.PubMed/NCBI View Article : Google Scholar
|
|
55
|
Van Pottelberge GR, Mestdagh P, Bracke KR,
Thas O, van Durme YM, Joos GF, Vandesompele J and Brusselle GG:
MicroRNA expression in induced sputum of smokers and patients with
chronic obstructive pulmonary disease. Am J Respir Crit Care Med.
183:898–906. 2011.PubMed/NCBI View Article : Google Scholar
|
|
56
|
Ashburner M, Ball CA, Blake JA, Botstein
D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT,
et al: Gene ontology: Tool for the unification of biology. The gene
ontology consortium. Nat Genet. 25:25–29. 2000.PubMed/NCBI View Article : Google Scholar
|
|
57
|
Nakamura H: Genetics of COPD. Allergol
Int. 60:253–258. 2011.PubMed/NCBI View Article : Google Scholar
|
|
58
|
Ostridge K, Williams N, Kim V, Bennett M,
Harden S, Welch L, Bourne S, Coombs NA, Elkington PT, Staples KJ
and Wilkinson TM: Relationship between pulmonary matrix
metalloproteinases and quantitative CT markers of small airways
disease and emphysema in COPD. Thorax. 71:126–132. 2016.PubMed/NCBI View Article : Google Scholar
|
|
59
|
Even B, Fayad-Kobeissi S, Gagliolo JM,
Motterlini R, Boczkowski J, Foresti R and Dagouassat M: Heme
oxygenase-1 induction attenuates senescence in chronic obstructive
pulmonary disease lung fibroblasts by protecting against
mitochondria dysfunction. Aging Cell. 17(e12837)2018.PubMed/NCBI View Article : Google Scholar
|
|
60
|
de Jong OG, Verhaar MC, Chen Y, Vader P,
Gremmels H, Posthuma G, Schiffelers RM, Gucek M and van Balkom BW:
Cellular stress conditions are reflected in the protein and RNA
content of endothelial cell-derived exosomes. J Extracell Vesicles.
1:2012.PubMed/NCBI View Article : Google Scholar
|
|
61
|
Beninson LA and Fleshner M: Exosomes: An
emerging factor in stress-induced immunomodulation. Semin Immunol.
26:394–401. 2014.PubMed/NCBI View Article : Google Scholar
|
|
62
|
Iraci N, Leonardi T, Gessler F, Vega B and
Pluchino S: Focus on extracellular vesicles: Physiological role and
signalling properties of extracellular membrane vesicles. Int J Mol
Sci. 17(171)2016.PubMed/NCBI View Article : Google Scholar
|
|
63
|
Pisitkun T, Shen RF and Knepper MA:
Identification and proteomic profiling of exosomes in human urine.
Proc Natl Acad Sci USA. 101:13368–13373. 2004.PubMed/NCBI View Article : Google Scholar
|
|
64
|
Song JE, Kim JS, Shin JH, Moon KW, Park
JK, Park KS and Lee EY: Role of synovial exosomes in osteoclast
differentiation in inflammatory arthritis. Cells.
10(120)2021.PubMed/NCBI View Article : Google Scholar
|
|
65
|
Hu Y, Qi C, Liu X, Zhang C, Gao J, Wu Y,
Yang J, Zhao Q, Li J, Wang X and Shen L: Malignant ascites-derived
exosomes promote peritoneal tumor cell dissemination and reveal a
distinct miRNA signature in advanced gastric cancer. Cancer Lett.
457:142–150. 2019.PubMed/NCBI View Article : Google Scholar
|
|
66
|
Sun L, Zhu W, Zhao P, Zhang J, Lu Y, Zhu
Y, Zhao W, Liu Y, Chen Q and Zhang F: Down-regulated exosomal
MicroRNA-221-3p derived from senescent mesenchymal stem cells
impairs heart repair. Front Cell Dev Biol. 8(263)2020.PubMed/NCBI View Article : Google Scholar
|
|
67
|
Chen J, Hu C and Pan P: Extracellular
vesicle MicroRNA transfer in lung diseases. Front Physiol.
8(1028)2017.PubMed/NCBI View Article : Google Scholar
|
