Role of microRNA‑129 in cancer and non‑cancerous diseases (Review)
- Authors:
- Bingpeng Deng
- Xuan Tang
- Yong Wang
-
Affiliations: Department of Forensic Science, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, P.R. China - Published online on: June 30, 2021 https://doi.org/10.3892/etm.2021.10350
- Article Number: 918
-
Copyright: © Deng et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
This article is mentioned in:
Abstract
 |
 |
|
Zhang HD, Jiang LH, Sun DW, Li J and Ji ZL: The role of miR-130a in cancer. Breast Cancer. 24:521–527. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Gao Y, Feng B, Han S, Lu L, Chen Y, Chu X, Wang R and Chen L: MicroRNA-129 in human cancers: From tumorigenesis to clinical treatment. Cell Physiol Biochem. 39:2186–2202. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Cai X, Hagedorn CH and Cullen BR: Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA. 10:1957–1966. 2004.PubMed/NCBI View Article : Google Scholar | |
|
Jiang Z, Zhang Y, Chen X, Wu P and Chen D: Inactivation of the Wnt/β-catenin signaling pathway underlies inhibitory role of microRNA-129-5p in epithelial-mesenchymal transition and angiogenesis of prostate cancer by targeting ZIC2. Cancer Cell Int. 19(271)2019.PubMed/NCBI View Article : Google Scholar | |
|
Wang X, Peng L, Gong X, Zhang X and Sun R: LncRNA HIF1A-AS2 promotes osteosarcoma progression by acting as a sponge of miR-129-5p. Aging (Albany NY). 11:11803–11813. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Obsil T: 14-3-3 proteins-a family of universal scaffolds and regulators. Semin Cell Dev Biol. 22:661–662. 2011.PubMed/NCBI View Article : Google Scholar | |
|
Meng R, Fang J, Yu Y, Hou LK, Chi JR, Chen AX, Zhao Y and Cao XC: miR-129-5p suppresses breast cancer proliferation by targeting CBX4. Neoplasma. 65:572–578. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Yu D, Han GH, Zhao X, Liu X, Xue K, Wang D and Xu CB: MicroRNA-129-5p suppresses nasopharyngeal carcinoma lymphangiogenesis and lymph node metastasis by targeting ZIC2. Cell Oncol (Dordr). 43:249–261. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Wang J, Ye C, Liu J and Hu Y: UCA1 confers paclitaxel resistance to ovarian cancer through miR-129/ABCB1 axis. Biochem Biophys Res Commun. 501:1034–1040. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Wu Q, Meng WY, Jie Y and Zhao H: LncRNA MALAT1 induces colon cancer development by regulating miR-129-5p/HMGB1 axis. J Cell Physiol. 233:6750–6757. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Xiao N, Zhang J, Chen C, Wan Y, Wang N and Yang J: miR-129-5p improves cardiac function in rats with chronic heart failure through targeting HMGB1. Mamm Genome. 30:276–288. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Hübner A, Jaeschke A and Davis RJ: Oncogene addiction: Role of signal attenuation. Dev Cell. 11:752–754. 2006.PubMed/NCBI View Article : Google Scholar | |
|
Yang W and Sun P: Downregulation of microRNA-129-5p increases the risk of intervertebral disc degeneration by promoting the apoptosis of nucleus pulposus cells via targeting BMP2. J Cell Biochem. 120:19684–19690. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Patrick E, Rajagopal S, Wong HA, McCabe C, Xu J, Tang A, Imboywa SH, Schneider JA, Pochet N, Krichevsky AM, et al: Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease. Mol Neurodegener. 12(51)2017.PubMed/NCBI View Article : Google Scholar | |
|
Pahlavani M, Wijayatunga NN, Kalupahana NS, Ramalingam L, Gunaratne PH, Coarfa C, Rajapakshe K, Kottapalli P and Moustaid-Moussa N: Transcriptomic and microRNA analyses of gene networks regulated by eicosapentaenoic acid in brown adipose tissue of diet-induced obese mice. Biochim Biophys Acta Mol Cell Biol Lipids. 1863:1523–1531. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Demirsoy IH, Ertural DY, Balci Ş, Çınkır Ü, Sezer K, Tamer L and Aras N: Profiles of circulating MiRNAs following metformin treatment in patients with type 2 diabetes. J Med Biochem. 37:499–506. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Arend RC, Londoño-Joshi AI, Straughn JM Jr and Buchsbaum DJ: The Wnt/β-catenin pathway in ovarian cancer: A review. Gynecol Oncol. 131:772–779. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Murillo-Garzón V and Kypta R: WNT signalling in prostate cancer. Nature reviews. Urology. 14:683–696. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Tang PM, Zhou S, Meng XM, Wang QM, Li CJ, Lian GY, Huang XR, Tang YJ, Guan XY, Yan BP, et al: Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development. Nat Commun. 8(14677)2017.PubMed/NCBI View Article : Google Scholar | |
|
Gao G, Xiu D, Yang B, Sun D, Wei X, Ding Y, Ma Y and Wang Z: miR-129-5p inhibits prostate cancer proliferation via targeting ETV1. OncoTargets and Ther. 12:3531–3544. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Jia Y, Gao Y and Dou J: Effects of miR-129-3p on biological functions of prostate cancer cells through targeted regulation of Smad3. Oncol Lett. 19:1195–1202. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Hu Z, Guo J, Zhao M, Jiang T and Yang X: Predictive values of miR-129 and miR-139 for efficacy on patients with prostate cancer after chemotherapy and prognostic correlation. Oncol Lett. 18:6187–6195. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Zhang RM, Tang T, Yu HM and Yao XD: LncRNA DLX6-AS1/miR-129-5p/DLK1 axis aggravates stemness of osteosarcoma through Wnt signaling. Biochem Biophys Res Commun. 507:260–266. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Chen X, Liu M, Meng F, Sun B, Jin X and Jia C: The long noncoding RNA HIF1A-AS2 facilitates cisplatin resistance in bladder cancer. J Cell Biochem. 120:243–252. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Lin J, Shi Z, Yu Z and He Z: LncRNA HIF1A-AS2 positively affects the progression and EMT formation of colorectal cancer through regulating miR-129-5p and DNMT3A. Biomed Pharmacother. 98:433–439. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Lin H, Zhao Z, Hao Y and He J and He J: Long noncoding RNA HIF1A-AS2 facilitates cell survival and migration by sponging miR-33b-5p to modulate SIRT6 expression in osteosarcoma. Biochem Cell Biol. 98:284–292. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Hou PS, Chuang CY, Kao CF, Chou SJ, Stone L, Ho HN, Chien CL and Kuo HC: LHX2 regulates the neural differentiation of human embryonic stem cells via transcriptional modulation of PAX6 and CER1. Nucleic Acids Res. 41:7753–7770. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Tomann P, Paus R, Millar SE, Scheidereit C and Schmidt-Ullrich R: Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth. Development. 143:1512–1522. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Liang TS, Zheng YJ, Wang J, Zhao JY, Yang DK and Liu ZS: MicroRNA-506 inhibits tumor growth and metastasis in nasopharyngeal carcinoma through the inactivation of the Wnt/β-catenin signaling pathway by down-regulating LHX2. J Exp Clin Cancer Res. 38(97)2019.PubMed/NCBI View Article : Google Scholar | |
|
Kuzmanov A, Hopfer U, Marti P, Meyer-Schaller N, Yilmaz M and Christofori G: LIM-homeobox gene 2 promotes tumor growth and metastasis by inducing autocrine and paracrine PDGF-B signaling. Mol Oncol. 8:401–416. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Zhou F, Gou S, Xiong J, Wu H, Wang C and Liu T: Oncogenicity of LHX2 in pancreatic ductal adenocarcinoma. Mol Biol Rep. 41:8163–8167. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Song H, Liu J, Wu X, Zhou Y, Chen X, Chen J, Deng K, Mao C, Huang S and Liu Z: LHX2 promotes malignancy and inhibits autophagy via mTOR in osteosarcoma and is negatively regulated by miR-129-5p. Aging (Albany NY). 11:9794–9810. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Li G, Xie J and Wang J: Tumor suppressor function of miR-129-5p in lung cancer. Oncol Lett. 17:5777–5783. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Jeong BH, Jin HT, Choi EK, Carp RI and Kim YS: Lack of association between 14-3-3 beta gene (YWHAB) polymorphisms and sporadic Creutzfeldt-Jakob disease (CJD). Mol Biol Rep. 39:10647–10653. 2012.PubMed/NCBI View Article : Google Scholar | |
|
Xu C, Du Z, Ren S, Liang X and Li H: MiR-129-5p sensitization of lung cancer cells to etoposide-induced apoptosis by reducing YWHAB. J Cancer. 11:858–866. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Jacob S, Nayak S, Fernandes G, Barai RS, Menon S, Chaudhari UK, Kholkute SD and Sachdeva G: Androgen receptor as a regulator of ZEB2 expression and its implications in epithelial-to-mesenchymal transition in prostate cancer. Endocr Relat Cancer. 21:473–486. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Li X, Li C, Bi H, Bai S, Zhao L, Zhang J and Qi C: Targeting ZEB2 By microRNA-129 in non-small cell lung cancer suppresses cell proliferation, invasion and migration via regulating Wnt/beta-catenin signaling pathway and epithelial-mesenchymal transition. Onco Targets Ther. 12:9165–9175. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Wang X, Li L, Wu Y, Zhang R, Zhang M, Liao D, Wang G, Qin G, Xu RH and Kang T: CBX4 suppresses metastasis via recruitment of HDAC3 to the Runx2 promoter in colorectal carcinoma. Cancer Res. 76:7277–7289. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Chaudhary LN, Wilkinson KH and Kong A: Triple-negative breast cancer: Who should receive neoadjuvant chemotherapy? Surg Oncol Clin N Am. 27:141–153. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Zuo Y, Li Y, Zhou Z, Ma M and Fu K: Long non-coding RNA MALAT1 promotes proliferation and invasion via targeting miR-129-5p in triple-negative breast cancer. Biomed Pharmacother. 95:922–928. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Del Mastro L and De Laurentiis M: Clinical applications of trastuzumab in the management of HER-2-positive breast cancer. Recenti Prog Med. 110:594–603. 2019.PubMed/NCBI View Article : Google Scholar : (In Italian). | |
|
Lu X, Ma J, Chu J, Shao Q, Zhang Y, Lu G, Li J, Huang X, Li W, Li Y, et al: MiR-129-5p sensitizes the response of Her-2 positive breast cancer to trastuzumab by reducing Rps6. Cell Physiol Biochem. 44:2346–2356. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Godbole M, Chandrani P, Gardi N, Dhamne H, Patel K, Yadav N, Gupta S, Badwe R and Dutt A: miR-129-2 mediates down-regulation of progesterone receptor in response to progesterone in breast cancer cells. Cancer Biol Ther. 18:801–805. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Xue J, Zhu X, Huang P, He Y, Xiao Y, Liu R and Zhao M: Expression of miR-129-5p and miR-433 in the serum of breast cancer patients and their relationship with clinicopathological features. Oncol Lett. 20:2771–2778. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Zeng H, Wang L, Wang J, Chen T, Li H, Zhang K, Chen J, Zhen S, Tuluhong D, Li J and Wang S: microRNA-129-5p suppresses Adriamycin resistance in breast cancer by targeting SOX2. Arch Biochem Biophys. 651:52–60. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Yi W, Wang J, Yao Z, Kong Q, Zhang N, Mo W, Xu L and Li X: The expression status of ZIC2 as a prognostic marker for nasopharyngeal carcinoma. Int J Clin Exp Pathol. 11:4446–4460. 2018.PubMed/NCBI | |
|
Matheson CJ, Backos DS and Reigan P: Targeting WEE1 kinase in cancer. Trends Pharmacol Sci. 37:872–881. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Zhang H, Lu J, Jiang C and Lu W: miR-129-1-3p reverses cisplatin resistance of HNE1/CDDP human nasopharyngeal carcinoma cells by targeting inhibition of WEE1 kinase. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 35:1014–1019. 2019.PubMed/NCBI(In Chinese). | |
|
Gu LP, Jin S, Xu RC, Zhang J, Geng YC, Shao XY and Qin LB: Long non-coding RNA PCAT-1 promotes tumor progression by inhibiting miR-129-5p in human ovarian cancer. Arch Med Sci. 15:513–521. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Liu F, Zhao H, Gong L, Yao L, Li Y and Zhang W: MicroRNA-129-3p functions as a tumor suppressor in serous ovarian cancer by targeting BZW1. Int J Clin Exp Pathol. 11:5901–5908. 2018.PubMed/NCBI | |
|
Zhang H and Lu W: LncRNA SNHG12 regulates gastric cancer progression by acting as a molecular sponge of miR-320. Mol Med Rep. 17:2743–2749. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Wang JZ, Xu CL, Wu H and Shen SJ: LncRNA SNHG12 promotes cell growth and inhibits cell apoptosis in colorectal cancer cells. Braz J Med Biol Res. 50(e6079)2017.PubMed/NCBI View Article : Google Scholar | |
|
Sun D and Fan XH: LncRNA SNHG12 accelerates the progression of ovarian cancer via absorbing miRNA-129 to upregulate SOX4. Eur Rev Med Pharmacol Sci. 23:2345–2352. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Prensner JR, Iyer MK, Balbin OA, Dhanasekaran SM, Cao Q, Brenner JC, Laxman B, Asangani IA, Grasso CS, Kominsky HD, et al: Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression. Nat Biotechnol. 29:742–749. 2011.PubMed/NCBI View Article : Google Scholar | |
|
Bi M, Yu H, Huang B and Tang C: Long non-coding RNA PCAT-1 over-expression promotes proliferation and metastasis in gastric cancer cells through regulating CDKN1A. Gene. 626:337–343. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Wen J, Xu J, Sun Q, Xing C and Yin W: Upregulation of long non coding RNA PCAT-1 contributes to cell proliferation, migration and apoptosis in hepatocellular carcinoma. Mol Med Rep. 13:4481–4486. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Qiao L, Liu X, Tang Y, Zhao Z, Zhang J and Feng Y: Down regulation of the long non-coding RNA PCAT-1 induced growth arrest and apoptosis of colorectal cancer cells. Life Sci. 188:37–44. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Wang H, Guan Z, He K, Qian J, Cao J and Teng L: LncRNA UCA1 in anti-cancer drug resistance. Oncotarget. 8:64638–64650. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Tan G, Cao X, Dai Q, Zhang B, Huang J, Xiong S, Zhang Yy, Chen W, Yang J and Li H: A novel role for microRNA-129-5p in inhibiting ovarian cancer cell proliferation and survival via direct suppression of transcriptional co-activators YAP and TAZ. Oncotarget. 6:8676–8686. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Pronina IV, Loginov VI, Burdennyy AM, Fridman MV, Kazubskaya TP, Dmitriev AA and Braga EA: Expression and DNA methylation alterations of seven cancer-associated 3p genes and their predicted regulator miRNAs (miR-129-2, miR-9-1) in breast and ovarian cancers. Gene. 576:483–491. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Kang R, Xie Y, Zhang Q, Hou W, Jiang Q, Zhu S, Liu J, Zeng D, Wang H, Bartlett DL, et al: Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer. Cell Res. 27:916–932. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Amornsupak K, Jamjuntra P, Warnnissorn M, O-Charoenrat P, Sa-Nguanraksa D, Thuwajit P, Eccles SA and Thuwajit C: High ASMA+ fibroblasts and low cytoplasmic HMGB1+ breast cancer cells predict poor prognosis. Clin Breast Cancer. 17:441–452.e2. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Chou YE, Yang PJ, Lin CY, Chen YY, Chiang WL, Lin PX, Huang ZY, Huang M, Ho YC and Yang SF: The impact of HMGB1 polymorphisms on prostate cancer progression and clinicopathological characteristics. Int J Environ Res Public Health. 17(7247)2020.PubMed/NCBI View Article : Google Scholar | |
|
Fu R, Yang P, Sajid A and Li Z: Avenanthramide A induces cellular senescence via miR-129-3p/Pirh2/p53 signaling pathway to suppress colon cancer growth. J Agric Food Chem. 67:4808–4816. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Wu N, Fesler A, Liu H and Ju J: Development of novel miR-129 mimics with enhanced efficacy to eliminate chemoresistant colon cancer stem cells. Oncotarget. 9:8887–8897. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Kang M, Li Y, Liu W, Wang R, Tang A, Hao H, Liu Z and Ou H: miR-129-2 suppresses proliferation and migration of esophageal carcinoma cells through downregulation of SOX4 expression. Int J Mol Med. 32:51–58. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Li Z, Lu J, Zeng G, Pang J, Zheng X, Feng J and Zhang J: MiR-129-5p inhibits liver cancer growth by targeting calcium calmodulin-dependent protein kinase IV (CAMK4). Cell Death Dis. 10(789)2019.PubMed/NCBI View Article : Google Scholar | |
|
Lu JL, Zhao L, Han SC, Bi JL, Liu HX, Yue C and Lin L: MiR-129 is involved in the occurrence of uterine fibroid through inhibiting TET1. Eur Rev Med Pharmacol Sci. 22:4419–4426. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Wang YF, Yang HY, Shi XQ and Wang Y: Upregulation of microRNA-129-5p inhibits cell invasion, migration and tumor angiogenesis by inhibiting ZIC2 via downregulation of the Hedgehog signaling pathway in cervical cancer. Cancer Biol Ther. 19:1162–1173. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Lv X, Zhou W, Sun J, Lin R, Ding L, Xu M, Xu Y, Zhao Z, Chen Y, Bi Y, et al: Visceral adiposity is significantly associated with type 2 diabetes in middle-aged and elderly Chinese women: A cross-sectional study. J Diabetes. 9:920–928. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Hruby A and Hu FB: The epidemiology of obesity: A big picture. Pharmacoeconomics. 33:673–689. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Yu YH: Making sense of metabolic obesity and hedonic obesity. J Diabetes. 9:656–666. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Ahmed M, Nguyen HQ, Hwang JS, Zada S, Lai TH, Kang SS and Kim DR: Systematic characterization of autophagy-related genes during the adipocyte differentiation using public-access data. Oncotarget. 9:15526–15541. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Zhang HY, Wang YH, Wang Y, Qu YN, Huang XH, Yang HX, Zhao CM, He Y, Li SW, Zhou J, et al: miR-129-5p regulates the immunomodulatory functions of adipose-derived stem cells via targeting Stat1 signaling. Stem Cells Int. 2019(2631024)2019.PubMed/NCBI View Article : Google Scholar | |
|
He C and Klionsky DJ: Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet. 43:67–93. 2009.PubMed/NCBI View Article : Google Scholar | |
|
Suryawan A and Hu CY: Effect of serum on differentiation of porcine adipose stromal-vascular cells in primary culture. Comp Biochem Physiol Comp Physiol. 105:485–492. 1993.PubMed/NCBI View Article : Google Scholar | |
|
Harding TM, Hefner-Gravink A, Thumm M and Klionsky DJ: Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway. J Biol Chem. 271:17621–17624. 1996.PubMed/NCBI View Article : Google Scholar | |
|
Ahmed M, Hwang JS, Lai TH, Zada S, Nguyen HQ, Pham TM, Yun M and Kim DR: Co-expression network analysis of AMPK and autophagy gene products during adipocyte differentiation. Int J Mol Sci. 19(1808)2018.PubMed/NCBI View Article : Google Scholar | |
|
Fu X, Jin L, Han L, Yuan Y, Mu Q, Wang H, Yang J, Ning G, Zhou D and Zhang Z: miR-129-5p inhibits adipogenesis through autophagy and may be a potential biomarker for obesity. Int J Endocrinol. 2019(5069578)2019.PubMed/NCBI View Article : Google Scholar | |
|
Bielawiec P, Harasim-Symbor E and Chabowski A: Phytocannabinoids: Useful drugs for the treatment of obesity? Special focus on cannabidiol. Front Endocrinol (Lausanne). 11(114)2020.PubMed/NCBI View Article : Google Scholar | |
|
Gracia A, Miranda J, Fernández-Quintela A, Eseberri I, Garcia-Lacarte M, Milagro FI, Martínez JA, Aguirre L and Portillo MP: Involvement of miR-539-5p in the inhibition of de novo lipogenesis induced by resveratrol in white adipose tissue. Food Funct. 7:1680–1688. 2016.PubMed/NCBI View Article : Google Scholar | |
|
Dinatolo E, Sciatti E, Anker MS, Lombardi C, Dasseni N and Metra M: Updates in heart failure: What last year brought to us. ESC Heart Fail. 5:989–1007. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Murphy SP, Kakkar R, McCarthy CP and Januzzi JL Jr: Inflammation in heart failure: JACC state-of-the-art review. J Am Coll Cardiol. 75:1324–1340. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Martinotti S, Patrone M and Ranzato E: Emerging roles for HMGB1 protein in immunity, inflammation, and cancer. Immunotargets Ther. 4:101–109. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Volz HC, Laohachewin D, Schellberg D, Wienbrandt AR, Nelles M, Zugck C, Kaya Z, Katus HA and Andrassy M: HMGB1 is an independent predictor of death and heart transplantation in heart failure. Clin Res Cardiol. 101:427–435. 2012.PubMed/NCBI View Article : Google Scholar | |
|
Gorgulho CM, Romagnoli GG, Bharthi R and Lotze MT: Johnny on the Spot-chronic inflammation is driven by HMGB1. Front Immunol. 10(1561)2019.PubMed/NCBI View Article : Google Scholar | |
|
Piorecka K, Smith D, Kurjata J, Stanczyk M and Stanczyk WA: Synthetic routes to nanoconjugates of anthracyclines. Bioorg Chem. 96(103617)2020.PubMed/NCBI View Article : Google Scholar | |
|
Anakwue R: Cytotoxic-induced heart failure among breast cancer patients in Nigeria: A call to prevent today's cancer patients from being tomorrow's cardiac patients. Ann Afr Med. 19:1–7. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Bansal N, Adams MJ, Ganatra S, Colan SD, Aggarwal S, Steiner R, Amdani S, Lipshultz ER and Lipshultz SE: Strategies to prevent anthracycline-induced cardiotoxicity in cancer survivors. Cardiooncology. 5(18)2019.PubMed/NCBI View Article : Google Scholar | |
|
Cai F, Luis MAF, Lin X, Wang M, Cai L, Cen C and Biskup E: Anthracycline-induced cardiotoxicity in the chemotherapy treatment of breast cancer: Preventive strategies and treatment. Mol Clin Oncol. 11:15–23. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Lim CC, Zuppinger C, Guo X, Kuster GM, Helmes M, Eppenberger HM, Suter TM, Liao R and Sawyer DB: Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes. J Biol Chem. 279:8290–8299. 2004.PubMed/NCBI View Article : Google Scholar | |
|
Li Q, Qin M, Tan Q, Li T, Gu Z, Huang P and Ren L: MicroRNA-129-1-3p protects cardiomyocytes from pirarubicin-induced apoptosis by down-regulating the GRIN2D-mediated Ca2+ signalling pathway. J Cell Mol Med. 24:2260–2271. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Javadov S, Hunter JC, Barreto-Torres G and Parodi-Rullan R: Targeting the mitochondrial permeability transition: Cardiac ischemia-reperfusion versus carcinogenesis. Cell Physiol Biochem. 27:179–190. 2011.PubMed/NCBI View Article : Google Scholar | |
|
Hajdú T, Juhász T, Szűcs-Somogyi C, Rácz K and Zákány R: NR1 and NR3B Composed intranuclear N-methyl-d-aspartate receptor complexes in human melanoma cells. Int J Mol Sci. 19(1929)2018.PubMed/NCBI View Article : Google Scholar | |
|
Liu XR, Rempel DL and Gross ML: Composite conformational changes of signaling proteins upon ligand binding revealed by a single approach: Calcium-calmodulin study. Anal Chem. 91:12560–12567. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Hwang HS, Baldo MP, Rodriguez JP, Faggioni M and Knollmann BC: Efficacy of flecainide in catecholaminergic polymorphic ventricular tachycardia is mutation-independent but reduced by calcium overload. Front Physiol. 10(992)2019.PubMed/NCBI View Article : Google Scholar | |
|
Wei Q, Zhou HY, Shi XD, Cao HY and Qin L: Long noncoding RNA NEAT1 promotes myocardiocyte apoptosis and suppresses proliferation through regulation of miR-129-5p. J Cardiovasc Pharmacol. 74:535–541. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Camfield P and Camfield C: Regression in children with epilepsy. Neurosci Biobehav Rev. 96:210–218. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Devinsky O, Vezzani A, Najjar S, De Lanerolle NC and Rogawski MA: Glia and epilepsy: Excitability and inflammation. Trends Neurosci. 36:174–184. 2013.PubMed/NCBI View Article : Google Scholar | |
|
Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, Engel J Jr, Forsgren L, French JA, Glynn M, et al: ILAE official report: A practical clinical definition of epilepsy. Epilepsia. 55:475–482. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Hunsberger JG, Bennett AH, Selvanayagam E, Duman RS and Newton SS: Gene profiling the response to kainic acid induced seizures. Brain research. Mol Brain Res. 141:95–112. 2005.PubMed/NCBI View Article : Google Scholar | |
|
Sharma AK, Searfoss GH, Reams RY, Jordan WH, Snyder PW, Chiang AY, Jolly RA and Ryan TP: Kainic acid-induced F-344 rat model of mesial temporal lobe epilepsy: Gene expression and canonical pathways. Toxicol Pathol. 37:776–789. 2009.PubMed/NCBI View Article : Google Scholar | |
|
Gorter JA, Iyer A, White I, Colzi A, van Vliet EA, Sisodiya S and Aronica E: Hippocampal subregion-specific microRNA expression during epileptogenesis in experimental temporal lobe epilepsy. Neurobiol Dis. 62:508–520. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Pernice HF, Schieweck R, Kiebler MA and Popper B: mTOR and MAPK: From localized translation control to epilepsy. BMC Neurosci. 17(73)2016.PubMed/NCBI View Article : Google Scholar | |
|
Wu DM, Zhang YT, Lu J and Zheng YL: Effects of microRNA-129 and its target gene c-Fos on proliferation and apoptosis of hippocampal neurons in rats with epilepsy via the MAPK signaling pathway. J Cell Physiol. 233:6632–6643. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Rajman M, Metge F, Fiore R, Khudayberdiev S, Aksoy-Aksel A, Bicker S, Ruedell Reschke C, Raoof R, Brennan GP, Delanty N, et al: A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses. EMBO J. 36:1770–1787. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Siddoway B, Hou H and Xia H: Molecular mechanisms of homeostatic synaptic downscaling. Neuropharmacology. 78:38–44. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Wan Y and Yang ZQ: LncRNA NEAT1 affects inflammatory response by targeting miR-129-5p and regulating Notch signaling pathway in epilepsy. Cell Cycle. 19:419–431. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Tuomi T, Santoro N, Caprio S, Cai M, Weng J and Groop L: The many faces of diabetes: A disease with increasing heterogeneity. Lancet. 383:1084–1094. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, et al: Tumour exosome integrins determine organotropic metastasis. Nature. 527:329–335. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, et al: Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. 523:177–182. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Fu Q, Jiang H, Wang Z, Wang X, Chen H, Shen Z, Xiao L, Guo X and Yang T: Injury factors alter miRNAs profiles of exosomes derived from islets and circulation. Aging (Albany NY). 10:3986–3999. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Collinson P: Laboratory medicine is faced with the evolution of medical practice. J Med Biochem. 36:211–215. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Wicks K, Torbica T and Mace KA: Myeloid cell dysfunction and the pathogenesis of the diabetic chronic wound. Semin Immunol. 26:341–353. 2014.PubMed/NCBI View Article : Google Scholar | |
|
Williams MD and Nadler JL: Inflammatory mechanisms of diabetic complications. Curr Diabet Rep. 7:242–248. 2007.PubMed/NCBI View Article : Google Scholar | |
|
Daigle I and Simon HU: Critical role for caspases 3 and 8 in neutrophil but not eosinophil apoptosis. Int Arch Allergy Immuno. 126:147–156. 2001.PubMed/NCBI View Article : Google Scholar | |
|
Pongracz J, Webb P, Wang K, Deacon E, Lunn OJ and Lord JM: Spontaneous neutrophil apoptosis involves caspase 3-mediated activation of protein kinase C-delta. J Biol Chem. 274:37329–37334. 1999.PubMed/NCBI View Article : Google Scholar | |
|
Zhao R, Guan DW, Zhang W, Du Y, Xiong CY, Zhu BL and Zhang JJ: Increased expressions and activations of apoptosis-related factors in cell signaling during incised skin wound healing in mice: A preliminary study for forensic wound age estimation. Leg Med (Tokyo, Japan). 11 (Suppl 1):S155–S160. 2009.PubMed/NCBI View Article : Google Scholar | |
|
Willenborg S, Lucas T, van Loo G, Knipper JA, Krieg T, Haase I, Brachvogel B, Hammerschmidt M, Nagy A, Ferrara N, et al: CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood. 120:613–625. 2012.PubMed/NCBI View Article : Google Scholar | |
|
Devalaraja RM, Nanney LB, Du J, Qian Q, Yu Y, Devalaraja MN and Richmond A: Delayed wound healing in CXCR2 knockout mice. J Invest Dermatol. 115:234–244. 2000.PubMed/NCBI View Article : Google Scholar | |
|
Umehara T, Mori R, Mace KA, Murase T, Abe Y, Yamamoto T and Ikematsu K: Identification of specific miRNAs in neutrophils of type 2 diabetic mice: Overexpression of miRNA-129-2-3p accelerates diabetic wound healing. Diabetes. 68:617–630. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Wang W, Yang C, Wang XY, Zhou LY, Lao GJ, Liu D, Wang C, Hu MD, Zeng TT, Yan L and Ren M: MicroRNA-129 and -335 promote diabetic wound healing by inhibiting Sp1-mediated MMP-9 expression. Diabetes. 67:1627–1638. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Jobin PG, Butler GS and Overall CM: New intracellular activities of matrix metalloproteinases shine in the moonlight. Biochim Biophys Acta Mol Cell Res. 1864:2043–2055. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Overall CM, Wrana JL and Sodek J: Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression. J Biol Chem. 266:14064–14071. 1991.PubMed/NCBI | |
|
McBeth J and Jones K: Epidemiology of chronic musculoskeletal pain. Best Pract Res Clin Rheumatol. 21:403–425. 2007.PubMed/NCBI View Article : Google Scholar | |
|
Wieser S, Horisberger B, Schmidhauser S, Eisenring C, Brügger U, Ruckstuhl A, Dietrich J, Mannion AF, Elfering A, Tamcan O and Müller U: Cost of low back pain in Switzerland in 2005. Eur J Health Econ. 12:455–467. 2011.PubMed/NCBI View Article : Google Scholar | |
|
Dario AB, Ferreira ML, Refshauge KM, Lima TS, Ordoñana JR and Ferreira PH: The relationship between obesity, low back pain, and lumbar disc degeneration when genetics and the environment are considered: A systematic review of twin studies. Spine J. 15:1106–1117. 2015.PubMed/NCBI View Article : Google Scholar | |
|
Johnson WE, Eisenstein SM and Roberts S: Cell cluster formation in degenerate lumbar intervertebral discs is associated with increased disc cell proliferation. Connect Tissue Res. 42:197–207. 2001.PubMed/NCBI View Article : Google Scholar | |
|
Kim KW, Lim TH, Kim JG, Jeong ST, Masuda K and An HS: The origin of chondrocytes in the nucleus pulposus and histologic findings associated with the transition of a notochordal nucleus pulposus to a fibrocartilaginous nucleus pulposus in intact rabbit intervertebral discs. Spine (Phila Pa 1976). 28:982–990. 2003.PubMed/NCBI View Article : Google Scholar | |
|
Patterson JE: The pre-travel medical evaluation: The traveler with chronic illness and the geriatric traveler. Yale J Biol Med. 65:317–327. 1992.PubMed/NCBI | |
|
Li J, Yoon ST and Hutton WC: Effect of bone morphogenetic protein-2 (BMP-2) on matrix production, other BMPs, and BMP receptors in rat intervertebral disc cells. J Spinal Disord Tech. 17:423–428. 2004.PubMed/NCBI View Article : Google Scholar | |
|
Antunovic M, Matic I, Nagy B, Caput Mihalic K, Skelin J, Stambuk J, Josipovic P, Dzinic T, Paradzik M and Marijanovic I: FADD-deficient mouse embryonic fibroblasts undergo RIPK1-dependent apoptosis and autophagy after NB-UVB irradiation. J Photochem Photobiol B. 194:32–45. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Wang HQ, Yu XD, Liu ZH, Cheng X, Samartzis D, Jia LT, Wu SX, Huang J, Chen J and Luo ZJ: Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3. J Pathol. 225:232–242. 2011.PubMed/NCBI View Article : Google Scholar | |
|
Li N, Gao Q, Zhou W, Lv X, Yang X and Liu X: MicroRNA-129-5p affects immune privilege and apoptosis of nucleus pulposus cells via regulating FADD in intervertebral disc degeneration. Cell Cycle. 19:933–948. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Zhao K, Zhang Y, Kang L, Song Y, Wang K, Li S, Wu X, Hua W, Shao Z, Yang S and Yang C: Methylation of microRNA-129-5P modulates nucleus pulposus cell autophagy by targeting Beclin-1 in intervertebral disc degeneration. Oncotarget. 8:86264–86276. 2017.PubMed/NCBI View Article : Google Scholar | |
|
Maiuri MC, Criollo A, Tasdemir E, Vicencio JM, Tajeddine N, Hickman JA, Geneste O and Kroemer G: BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L). Autophagy. 3:374–376. 2007.PubMed/NCBI View Article : Google Scholar | |
|
Pluta R, Ulamek-Koziol M, Januszewski S and Czuczwar SJ: Gut microbiota and pro/prebiotics in Alzheimer's disease. Aging (Albany NY). 12:5539–5550. 2020.PubMed/NCBI View Article : Google Scholar | |
|
Shi Y, Han Y, Niu L, Li J and Chen Y: MiR-499 inhibited hypoxia/reoxygenation induced cardiomyocytes injury by targeting SOX6. Biotechnol Lett. 41:837–847. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Zaletel I, Schwirtlich M, Perović M, Jovanović M, Stevanović M, Kanazir S and Puškaš N: Early impairments of hippocampal neurogenesis in 5xFAD mouse model of Alzheimer's disease are associated with altered expression of SOXB transcription factors. J Alzheimer's Dis. 65:963–976. 2018.PubMed/NCBI View Article : Google Scholar | |
|
Zeng Z, Liu Y, Zheng W, Liu L, Yin H, Zhang S, Bai H, Hua L, Wang S, Wang Z, et al: MicroRNA-129-5p alleviates nerve injury and inflammatory response of Alzheimer's disease via downregulating SOX6. Cell Cycle. 18:3095–3110. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Geng Z, Xu F and Zhang Y: MiR-129-5p-mediated Beclin-1 suppression inhibits endothelial cell autophagy in atherosclerosis. Am J Transl Res. 8:1886–1894. 2016.PubMed/NCBI | |
|
Wan G, An Y, Tao J, Wang Y, Zhou Q, Yang R and Liang Q: MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1/TLR4/NF-κB pathway. Biosci Rep. 40(BSR20193315)2020.PubMed/NCBI View Article : Google Scholar | |
|
Huang S, Lv Z, Wen Y, Wei Y, Zhou L, Ke Y, Zhang Y, Xu Q, Li L, Guo Y, et al: miR-129-2-3p directly targets SYK gene and associates with the risk of ischaemic stroke in a Chinese population. J Cell Mol Med. 23:167–176. 2019.PubMed/NCBI View Article : Google Scholar | |
|
Xu M, Li H, Bai Y, He J, Chen R, An N, Li Y and Dong Y: miR-129 blocks secondary hyperparathyroidism-inducing Fgf23/αKlotho signaling in mice with chronic kidney disease. Am J Med Sci. 361:624–634. 2021.PubMed/NCBI View Article : Google Scholar | |
|
Zhu Y, Hu Y, Cheng X, Li Q and Niu Q: Elevated miR-129-5p attenuates hepatic fibrosis through the NF-κB signaling pathway via PEG3 in a carbon CCl4 rat model. J Mol Histol. 52:491–501. 2021.PubMed/NCBI View Article : Google Scholar |
