|
1
|
Boonpiyathad T, Sözener ZC, Satitsuksanoa
P and Akdis CA: Immunologic mechanisms in asthma. Semin Immunol.
46(101333)2019.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Insuela DBR, Ferrero MR, Coutinho DS,
Martins MA and Carvalho VF: Could arachidonic acid-derived
pro-resolving mediators be a new therapeutic strategy for asthma
therapy? Front Immunol. 11:580–598. 2020.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Holgate ST, Arshad HS, Roberts GC, Howarth
PH, Thurner P and Davies DE: A new look at the pathogenesis of
asthma. Clin Sci (Lond). 118:439–450. 2009.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Kudo M, Ishigatsubo Y and Aoki I:
Pathology of asthma. Front Microbiol. 4(263)2013.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Russell RJ and Brightling C: Pathogenesis
of asthma: Implications for precision medicine. Clin Sci (Lond).
131:1723–1735. 2017.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Birrell MA, De Alba J, Catley MC, Hardaker
E, Wong S, Collins M, Clarke DL, Farrow SN, Willson TM, Collins JL
and Belvisi MG: Liver X receptor agonists increase airway
reactivity in a model of asthma via increasing airway smooth muscle
growth. J Immunol. 181:4265–4271. 2008.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Castrillo A and Tontonoz P: Nuclear
receptors in macrophage biology: At the crossroads of lipid
metabolism and inflammation. Annu Rev Cell Dev Biol. 20:455–480.
2004.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Joseph SB, Castrillo A, Laffitte BA,
Mangelsdorf DJ and Tontonoz P: Reciprocal regulation of
inflammation and lipid metabolism by liver X receptors. Nat Med.
9:213–219. 2003.PubMed/NCBI View
Article : Google Scholar
|
|
9
|
Castrillo A, Joseph SB, Marathe C,
Mangelsdorf DJ and Tontonoz P: Liver X receptor-dependent
repression of matrix metalloproteinase-9 expression in macrophages.
J Biol Chem. 278:10443–10449. 2003.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Smet M, Van Hoecke L, De Beuckelaer A,
VanderBeken S, Naessens T, Vergote K, Willart M, Lambrecht BN,
Gustafsson JÅ, Steffensen KR and Grooten J: Cholesterol-sensing
liver X receptors stimulate Th2-driven allergic eosinophilic asthma
in mice. Immun Inflamm Dis. 4:350–361. 2016.PubMed/NCBI View
Article : Google Scholar
|
|
11
|
Bruemmer D, Collins AR, Noh G, Wang W,
Territo M, Arias-Magallona S, Fishbein MC, Blaschke F, Kintscher U,
Graf K, et al: Angiotensin II-accelerated atherosclerosis and
aneurysm formation is attenuated in osteopontin-deficient mice. J
Clin Invest. 112:1318–1331. 2003.PubMed/NCBI View
Article : Google Scholar
|
|
12
|
Ogawa D, Stone JF, Takata Y, Blaschke F,
Chu VH, Towler DA, Law RE, Hsueh WA and Bruemmer D: Liver x
receptor agonists inhibit cytokine-induced osteopontin expression
in macrophages through interference with activator protein-1
signaling pathways. Circ Res. 96:e59–e67. 2005.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Solan PD, Piraino G, Hake PW, Denenberg A,
O'Connor M, Lentsch A and Zingarelli B: Liver X receptor α
activation with the synthetic ligand T0901317 reduces lung injury
and inflammation after hemorrhage and resuscitation via inhibition
of the nuclear factor κB pathway. Shock. 35:367–374.
2011.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Wang D, Liu M, Wang Y, Luo M, Wang J, Dai
C, Yan P, Zhang X, Wang Y, Tang C and Xiao J: Synthetic LXR agonist
T0901317 attenuates lipopolysaccharide-induced acute lung injury in
rats. Int Immunopharmacol. 11:2098–2103. 2011.PubMed/NCBI View Article : Google Scholar
|
|
15
|
August A, Mueller C, Weaver V, Polanco TA,
Walsh ER and Cantorna MT: Nutrients, nuclear receptors,
inflammation, immunity lipids, PPAR, and allergic asthma. J Nutr.
136:695–699. 2006.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Lee KS, Park SJ, Hwang PH, Yi HK, Song CH,
Chai OH, Kim JS, Lee MK and Lee YC: PPAR-gamma modulates allergic
inflammation through up-regulation of PTEN. FASEB J. 19:1033–1035.
2005.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Zelcer N and Tontonoz P: Liver X receptors
as integrators of metabolic and inflammatory signaling. J Clin
Invest. 116:607–614. 2006.PubMed/NCBI View
Article : Google Scholar
|
|
18
|
Shi Y, Xu X, Tan Y, Mao S, Fang S and Gu
W: A liver-X-receptor ligand, T0901317, attenuates IgE production
and airway remodeling in chronic asthma model of mice. PLoS One.
9(e92668)2014.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Ogawa S, Lozach J, Benner C, Pascual G,
Tangirala RK, Westin S, Hoffmann A, Subramaniam S, David M,
Rosenfeld MG and Glass CK: Molecular determinants of crosstalk
between nuclear receptors and toll-like receptors. Cell.
122:707–721. 2005.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Castrillo A, Joseph SB, Marathe C,
Mangelsdorf DJ and Tontonoz P: Liver X receptor-dependent
repression of matrix metalloproteinase-9 expression in macrophages.
J Biol Chem. 278:10443–10449. 2003.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Michael LF, Schkeryantz JM and Burris TP:
The pharmacology of LXR. Mini Rev Med Chem. 5:729–740.
2005.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Zhao Z, Xu D, Li S, He B, Huang Y, Xu M,
Ren S, Li S, Wang H and Xie W: Activation of liver X receptor
attenuates oleic acid-induced acute respiratory distress syndrome.
Am J Pathol. 186:2614–2622. 2016.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Chen Y, Duan Y, Kang Y, Yang X, Jiang M,
Zhang L, Li G, Yin Z, Hu W, Dong P, et al: Activation of liver X
receptor induces macrophage interleukin-5 expression. J Biol Chem.
287:43340–43350. 2012.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Asayama K, Kobayashi T,
D'Alessandro-Gabazza CN, Toda M, Yasuma T, Fujimoto H, Okano T,
Saiki H, Takeshita A, Fujiwara K, et al: Protein S protects against
allergic bronchial asthma by modulating Th1/Th2 balance. Allergy.
75:2267–2278. 2020.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Heine G, Dahten A, Hilt K, Ernst D,
Milovanovic M, Hartmann B and Worm M: Liver X receptors control IgE
expression in B cells. J Immunol. 182:5276–5282. 2009.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Nunomura S, Endo K, Makishima M and Ra C:
Oxysterol represses high-affinity IgE receptor-stimulated mast cell
activation in Liver X receptor-dependent and -independent manners.
FEBS Lett. 584:1143–1148. 2010.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Gould HJ and Sutton BJ: IgE in allergy and
asthma today. Nat Rev Immunol. 8:205–217. 2008.PubMed/NCBI View
Article : Google Scholar
|
|
28
|
Jabara HH, Fu SM, Geha RS and Vercelli D:
CD40 and IgE: Synergism between anti-CD40 monoclonal antibody and
interleukin 4 in the induction of IgE synthesis by highly purified
human B cells. J Exp Med. 172:1861–1864. 1990.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Lala DS: The liver X receptors. Curr Opin
Investig. 6:934–943. 2005.PubMed/NCBI
|
|
30
|
Tontonoz P and Mangelsdorf DJ: Liver X
receptor signaling pathways in cardiovascular disease. Mol
Endocrinol. 17:985–993. 2003.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Chen S, Sims GP, Chen XX, Gu YY, Chen S
and Lipsky PE: Modulatory effects of 1,25-dihydroxyvitamin D3 on
human B cell differentiation. J Immunol. 179:1634–1647.
2007.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Hatano Y, Man MQ, Uchida Y, Crumrine D,
Mauro TM, Feingold KR, Elias PM and Holleran WM: Murine atopic
dermatitis responds to peroxisome proliferator-activated receptors
alpha and beta/delta (but not gamma) and liver X receptor
activators. J Allergy Clin Immunol. 125:160–169.e1-e5.
2010.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Delvecchio CJ, Bilan P, Radford K, Stephen
J, Trigatti BL, Cox G, Parameswaran K and Capone JP: Liver X
receptor stimulates cholesterol efflux and inhibits expression of
proinflammatory mediators in human airway smooth muscle cells. Mol
Endocrinol. 21:1324–1334. 2007.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Zhao L, Lei W, Deng C, Wu Z, Sun M, Jin Z,
Song Y, Yang Z, Jiang S, Shen M and Yang Y: The roles of liver X
receptor α in inflammation and inflammation-associated diseases. J
Cell Physiol. 36:4807–4828. 2021.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Hanashiro J, Muraosa Y, Toyotome T, Hirose
K, Watanabe A and Kamei K: Schizophyllum commune induces
IL-17-mediated neutrophilic airway inflammation in OVA-induced
asthma model mice. Sci Rep. 9(19321)2019.PubMed/NCBI View Article : Google Scholar
|
