Psoriasis beyond the skin: Ophthalmological changes (Review)

  • Authors:
    • Maria-Magdalena Constantin
    • Maria-Diana Ciurduc
    • Stefana Bucur
    • Rodica Olteanu
    • Razvan Adrian Ionescu
    • Traian Constantin
    • Florentina Furtunescu
  • View Affiliations

  • Published online on: July 12, 2021     https://doi.org/10.3892/etm.2021.10413
  • Article Number: 981
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Abstract

Psoriasis is a chronic, immune‑mediated inflammatory disease of unknown etiology that may be associated with abnormal T‑lymphocyte function. Ocular manifestations associated with psoriasis, particularly artropathic or pustular psoriasis, usually affect men, often during exacerbations of the disease. It has been reported that eye damage tends to occur later compared with cutaneous or joint manifestations, blindness being the most disabling complication. Previous studies have focused on ophthalmic manifestations and identified several etiopathogenic mechanisms. Psoriasis may be associated with eye complications such as lesions of the eyelids, conjunctiva and others, with systemic inflammation being the main contributor. In addition, the treatment used for psoriasis may cause ocular changes. The main ophthalmic manifestations associated with psoriasis are keratoconjunctivitis sicca, blepharitis, conjunctivitis and uveitis. The treatment of uveitis, perceived as one of the most serious eye conditions, is controversial and has yet to be clearly determined. Thus, the aim of the present review was to emphasize the importance of regular eye examination for patients with psoriasis, either those receiving biological treatment or those not receiving treatment, in order to diagnose and manage the disease appropriately.

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September-2021
Volume 22 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Constantin M, Ciurduc M, Bucur S, Olteanu R, Ionescu RA, Constantin T and Furtunescu F: Psoriasis beyond the skin: Ophthalmological changes (Review). Exp Ther Med 22: 981, 2021
APA
Constantin, M., Ciurduc, M., Bucur, S., Olteanu, R., Ionescu, R.A., Constantin, T., & Furtunescu, F. (2021). Psoriasis beyond the skin: Ophthalmological changes (Review). Experimental and Therapeutic Medicine, 22, 981. https://doi.org/10.3892/etm.2021.10413
MLA
Constantin, M., Ciurduc, M., Bucur, S., Olteanu, R., Ionescu, R. A., Constantin, T., Furtunescu, F."Psoriasis beyond the skin: Ophthalmological changes (Review)". Experimental and Therapeutic Medicine 22.3 (2021): 981.
Chicago
Constantin, M., Ciurduc, M., Bucur, S., Olteanu, R., Ionescu, R. A., Constantin, T., Furtunescu, F."Psoriasis beyond the skin: Ophthalmological changes (Review)". Experimental and Therapeutic Medicine 22, no. 3 (2021): 981. https://doi.org/10.3892/etm.2021.10413