|
1
|
Parry CD, Patra J and Rehm J: Alcohol
consumption and non-communicable diseases: Epidemiology and policy
implications. Addiction. 106:1718–1724. 2011.PubMed/NCBI View Article : Google Scholar
|
|
2
|
World Health Organization: Global status
report on alcohol and health. Geneva, Switzerland, WHO Press,
2018.
|
|
3
|
Rusyn I and Bataller R: Alcohol and
toxicity. J Hepatol. 59:387–388. 2013.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Bajaj JS: Alcohol, liver disease and the
gut microbiota. Nat Rev Gastroenterol Hepatol. 16:235–246.
2019.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Dubinkina VB, Tyakht AV, Odintsova VY,
Yarygin KS, Kovarsky BA, Pavlenko AV, Ischenko DS, Popenko AS,
Alexeev DG, Taraskina AY, et al: Links of gut microbiota
composition with alcohol dependence syndrome and alcoholic liver
disease. Microbiome. 5(141)2017.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Leclercq S, Matamoros S, Cani PD, Neyrinck
AM, Jamar F, Stärkel P, Windey K, Tremaroli V, Bäckhed F, Verbeke
K, et al: Intestinal permeability, gut-bacterial dysbiosis, and
behavioral markers of alcohol-dependence severity. Proc Natl Acad
Sci USA. 111:E4485–E4493. 2014.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Cho YE, Yu LR, Abdelmegeed MA, Yoo SH and
Song BJ: Apoptosis of enterocytes and nitration of junctional
complex proteins promote alcohol-induced gut leakiness and liver
injury. J Hepatol. 69:142–153. 2018.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Kirpich IA, McClain CJ, Vatsalya V,
Schwandt M, Phillips M, Falkner KC, Zhang L, Harwell C, George DT
and Umhau JC: Liver injury and endotoxemia in male and female
alcohol-dependent individuals admitted to an alcohol treatment
program. Alcohol Clin Exp Res. 41:747–757. 2017.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Pickard JM, Zeng MY, Caruso R and Núñez G:
Gut microbiota: Role in pathogen colonization, immune responses,
and inflammatory disease. Immunol Rev. 279:70–89. 2017.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Caruso R, Lo BC and Nunez G:
Host-microbiota interactions in inflammatory bowel disease. Nat Rev
Immunol. 20:411–426. 2020.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Sampson TR, Debelius JW, Thron T, Janssen
S, Shastri GG, Ilhan ZE, Challis C, Schretter CE, Rocha S,
Gradinaru V, et al: Gut microbiota regulate motor deficits and
neuroinflammation in a model of Parkinson's disease. Cell.
167:1469–1480.e12. 2016.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Fattorusso A, Di Genova L, Dell'Isola GB,
Mencaroni E and Esposito S: Autism spectrum disorders and the gut
microbiota. Nutrients. 11(521)2019.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Torres-Fuentes C, Schellekens H, Dinan TG
and Cryan JF: The microbiota-gut-brain axis in obesity. Lancet
Gastroenterol Hepatol. 2:747–756. 2017.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Bordalo Tonucci L, Dos Santos KM, De Luces
Fortes Ferreira CL, Ribeiro SM, De Oliveira LL and Martino HS: Gut
microbiota and probiotics: Focus on diabetes mellitus. Crit Rev
Food Sci Nutr. 57:2296–2309. 2017.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Bajaj JS, Kakiyama G, Zhao D, Takei H,
Fagan A, Hylemon P, Zhou H, Pandak WM, Nittono H, Fiehn O, et al:
Continued alcohol misuse in human cirrhosis is associated with an
impaired gut-liver axis. Alcohol Clin Exp Res. 41:1857–1865.
2017.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Bajaj JS, Heuman DM, Hylemon PB, Sanyal
AJ, White MB, Monteith P, Noble NA, Unser AB, Daita K, Fisher AR,
et al: Altered profile of human gut microbiome is associated with
cirrhosis and its complications. J Hepatol. 60:940–947.
2014.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Rao R: Endotoxemia and gut barrier
dysfunction in alcoholic liver disease. Hepatology. 50:638–644.
2009.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Szabo G and Bala S: Alcoholic liver
disease and the gut-liver axis. World J Gastroenterol.
16:1321–1329. 2010.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Mehta G, Macdonald S, Cronberg A, Rosselli
M, Khera-Butler T, Sumpter C, Al-Khatib S, Jain A, Maurice J,
Charalambous C, et al: Short-term abstinence from alcohol and
changes in cardiovascular risk factors, liver function tests and
cancer-related growth factors: A prospective observational study.
BMJ Open. 8(e020673)2018.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Lu W, Xu J, Taylor AW, Bewick BM, Fu Z, Wu
N, Qian L and Yin P: Analysis of the alcohol drinking behavior and
influencing factors among emerging adults and young adults: A
cross-sectional study in Wuhan, China. BMC Public Health.
19(458)2019.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Saburova L, Keenan K, Bobrova N, Leon DA
and Elbourne D: Alcohol and fatal life trajectories in Russia:
Understanding narrative accounts of premature male death in the
family. BMC Public Health. 11(481)2011.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Chiu WC, Huang YL, Chen YL, Peng HC, Liao
WH, Chuang HL, Chen JR and Yang SC: Synbiotics reduce
ethanol-induced hepatic steatosis and inflammation by improving
intestinal permeability and microbiota in rats. Food Funct.
6:1692–1700. 2015.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Sivieri K, Morales ML, Adorno MA, Sakamoto
IK, Saad SM and Rossi EA: Lactobacillus acidophilus CRL 1014
improved ‘gut health’ in the SHIME reactor. BMC Gastroenterol.
13(100)2013.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Ahrne S and Hagslatt ML: Effect of
lactobacilli on paracellular permeability in the gut. Nutrients.
3:104–117. 2011.PubMed/NCBI View Article : Google Scholar
|
|
25
|
van Baarlen P, Troost F, van der Meer C,
Hooiveld G, Boekschoten M, Brummer RJ and Kleerebezem M: Human
mucosal in vivo transcriptome responses to three lactobacilli
indicate how probiotics may modulate human cellular pathways. Proc
Natl Acad Sci USA. 108 (Suppl 1):S4562–S4569. 2011.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Susick RL Jr and Zannoni VG: Effect of
ascorbic acid on the consequences of acute alcohol consumption in
humans. Clin Pharmacol Ther. 41:502–509. 1987.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Xiaoqiang G, Wenjie L, Qiliang X, Hui D,
Caiyun Z, Yanzhong C and Xianglin D: Vitamin C protective role for
alcoholic liver disease in mice through regulating iron metabolism.
Toxicol Ind Health. 27:341–348. 2011.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Bertola A, Mathews S, Ki SH, Wang H and
Gao B: Mouse model of chronic and binge ethanol feeding (the NIAAA
model). Nat Protoc. 8:627–637. 2013.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Weigmann B, Tubbe I, Seidel D, Nicolaev A,
Becker C and Neurath MF: Isolation and subsequent analysis of
murine lamina propria mononuclear cells from colonic tissue. Nat
Protoc. 2:2307–2311. 2007.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Caporaso JG, Kuczynski J, Stombaugh J,
Bittinger K, Bushman FD, Costello EK, Fierer N, Peña AG, Goodrich
JK, Gordon JI, et al: QIIME allows analysis of high-throughput
community sequencing data. Nature Methods. 7:335–336.
2010.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Bjørkhaug ST, Aanes H, Neupane SP,
Bramness JG, Malvik S, Henriksen C, Skar V, Medhus AW and Valeur J:
Characterization of gut microbiota composition and functions in
patients with chronic alcohol overconsumption. Gut Microbes.
10:663–675. 2019.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Kuprys PV, Cannon AR, Shieh J, Iftekhar N,
Park SK, Eberhardt JM, Ding X and Choudhry MA: Alcohol decreases
intestinal ratio of Lactobacillus to Enterobacteriaceae and induces
hepatic immune tolerance in a murine model of DSS-colitis. Gut
Microbes. 12:1–16. 2020.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Sarin SK, Pande A and Schnabl B:
Microbiome as a therapeutic target in alcohol-related liver
disease. J Hepatol. 70:260–272. 2019.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Vacca M, Celano G, Calabrese FM,
Portincasa P, Gobbetti M and De Angelis M: The controversial role
of human gut lachnospiraceae. Microorganisms. 8(573)2020.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Bode C and Bode JC: Effect of alcohol
consumption on the gut. Best Pract Res Clin Gastroenterol.
17:575–592. 2003.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Szabo G: Gut-liver axis in alcoholic liver
disease. Gastroenterology. 148:30–36. 2015.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Seo B, Jeon K, Moon S, Lee K, Kim WK,
Jeong H, Cha KH, Lim MY, Kang W, Kweon MN, et al: Roseburia Spp.
Abundance associates with alcohol consumption in humans and its
administration ameliorates alcoholic fatty liver in mice. Cell Host
Microbe. 27:25–40.e6. 2020.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Roychowdhury S, Glueck B, Han Y, Mohammad
MA and Cresci GAM: A designer synbiotic attenuates chronic-binge
ethanol-induced gut-liver injury in mice. Nutrients.
11(97)2019.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Sönmez MF, Narin F, Akkuş D and Türkmen
AB: Melatonin and vitamin C ameliorate alcohol-induced oxidative
stress and eNOS expression in rat kidney. Ren Fail. 34:480–486.
2012.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Forsyth CB, Farhadi A, Jakate SM, Tang Y,
Shaikh M and Keshavarzian A: Lactobacillus GG treatment ameliorates
alcohol-induced intestinal oxidative stress, gut leakiness, and
liver injury in a rat model of alcoholic steatohepatitis. Alcohol.
43:163–172. 2009.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Yan AW, Fouts DE, Brandl J, Stärkel P,
Torralba M, Schott E, Tsukamoto H, Nelson KE, Brenner DA and
Schnabl B: Enteric dysbiosis associated with a mouse model of
alcoholic liver disease. Hepatology. 53:96–105. 2011.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Turroni F, Ventura M, Buttó LF, Duranti S,
O'Toole PW, Motherway MO and van Sinderen D: Molecular dialogue
between the human gut microbiota and the host: A Lactobacillus and
Bifidobacterium perspective. Cell Mol Life Sci. 71:183–203.
2014.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Bernet MF, Brassart D, Neeser JR and
Servin AL: Lactobacillus acidophilus LA 1 binds to cultured
human intestinal cell lines and inhibits cell attachment and cell
invasion by enterovirulent bacteria. Gut. 35:483–489.
1994.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Levine M, Conry-Cantilena C, Wang Y, Welch
RW, Washko PW, Dhariwal KR, Park JB, Lazarev A, Graumlich JF, King
J and Cantilena LR: Vitamin C pharmacokinetics in healthy
volunteers: Evidence for a recommended dietary allowance. Proc Natl
Acad Sci USA. 93:3704–3709. 1996.PubMed/NCBI View Article : Google Scholar
|
|
46
|
Round JL and Mazmanian SK: Inducible
Foxp3+ regulatory T-cell development by a commensal
bacterium of the intestinal microbiota. Proc Natl Acad Sci USA.
107:12204–12209. 2010.PubMed/NCBI View Article : Google Scholar
|
|
47
|
Smith PM, Howitt MR, Panikov N, Michaud M,
Gallini CA, Bohlooly-Y M, Glickman JN and Garrett WS: The microbial
metabolites, short-chain fatty acids, regulate colonic Treg cell
homeostasis. Science. 341:569–573. 2013.PubMed/NCBI View Article : Google Scholar
|
|
48
|
Li Z, Li D, Tsun A and Li B:
FOXP3+ regulatory T cells and their functional
regulation. Cell Mol Immunol. 12:558–565. 2015.PubMed/NCBI View Article : Google Scholar
|
|
49
|
Chaudhry A, Samstein RM, Treuting P, Liang
Y, Pils MC, Heinrich JM, Jack RS, Wunderlich FT, Brüning JC, Müller
W and Rudensky AY: Interleukin-10 signaling in regulatory T cells
is required for suppression of Th17 cell-mediated inflammation.
Immunity. 34:566–578. 2011.PubMed/NCBI View Article : Google Scholar
|
|
50
|
Cho YE and Song BJ: Pomegranate prevents
binge alcohol-induced gut leakiness and hepatic inflammation by
suppressing oxidative and nitrative stress. Redox Biol. 18:266–278.
2018.PubMed/NCBI View Article : Google Scholar
|
|
51
|
Lei P, Zhao W, Pang B, Yang X, Li BL, Ren
M and Shan YJ: Broccoli sprout extract alleviates alcohol-induced
oxidative stress and endoplasmic reticulum stress in C57BL/6 mice.
J Agric Food Chem. 66:5574–5580. 2018.PubMed/NCBI View Article : Google Scholar
|
|
52
|
Faith M, Sukumaran A, Pulimood AB and
Jacob M: How reliable an indicator of inflammation is
myeloperoxidase activity? Clin Chim Acta. 396:23–25.
2008.PubMed/NCBI View Article : Google Scholar
|
|
53
|
Olza J, Aguilera CM, Gil-Campos M, Leis R,
Bueno G, Martínez-Jiménez MD, Valle M, Cañete R, Tojo R, Moreno LA
and Gil A: Myeloperoxidase is an early biomarker of inflammation
and cardiovascular risk in prepubertal obese children. Diabetes
Care. 35:2373–2376. 2012.PubMed/NCBI View Article : Google Scholar
|
|
54
|
Shi J, Zhao Y, Wang Y, Gao W, Ding J, Li
P, Hu L and Shao F: Inflammatory caspases are innate immune
receptors for intracellular LPS. Nature. 514:187–192.
2014.PubMed/NCBI View Article : Google Scholar
|
|
55
|
Wang H, Song X, Li M, Wang X, Tao Y, Xiya
X, Liu H, Zhao Y, Chang D and Sha Q: The role of TLR4/NF-κB
signaling pathway in activated microglia of rats with chronic high
intraocular pressure and vitro scratch injury-induced microglia.
Int Immunopharmacol. 83(106395)2020.PubMed/NCBI View Article : Google Scholar
|
|
56
|
Furman D, Campisi J, Verdin E,
Carrera-Bastos P, Targ S, Franceschi C, Ferrucci L, Gilroy DW,
Fasano A, Miller GW, et al: Chronic inflammation in the etiology of
disease across the life span. Nat Med. 25:1822–1832.
2019.PubMed/NCBI View Article : Google Scholar
|
|
57
|
Valenzuela R and Videla LA: Impact of the
co-administration of N-3 fatty acids and olive oil components in
preclinical nonalcoholic fatty liver disease models: A mechanistic
view. Nutrients. 12(499)2020.PubMed/NCBI View Article : Google Scholar
|
|
58
|
Wang W, Xu MJ, Cai Y, Zhou Z, Cao H,
Mukhopadhyay P, Pacher P, Zheng S, Gonzalez FJ and Gao B:
Inflammation is independent of steatosis in a murine model of
steatohepatitis. Hepatology. 66:108–123. 2017.PubMed/NCBI View Article : Google Scholar
|
|
59
|
Echeverría F, Valenzuela R, Bustamante A,
Álvarez D, Ortiz M, Espinosa A, Illesca P, Gonzalez-Mañan D and
Videla LA: High-fat diet induces mouse liver steatosis with a
concomitant decline in energy metabolism: Attenuation by
eicosapentaenoic acid (EPA) or hydroxytyrosol (HT) supplementation
and the additive effects upon EPA and HT co-administration. Food
Funct. 10:6170–6183. 2019.PubMed/NCBI View Article : Google Scholar
|
|
60
|
Xie Z, Gao G, Wang H, Li E, Yuan Y, Xu J,
Zhang Z, Wang P, Fu Y, Zeng H, et al: Dehydroabietic acid
alleviates high fat diet-induced insulin resistance and hepatic
steatosis through dual activation of PPAR-γ and PPAR-α. Biomed
Pharmacother. 127(110155)2020.PubMed/NCBI View Article : Google Scholar
|
|
61
|
Gyamfi D, Everitt HE, Tewfik I, Clemens DL
and Patel VB: Hepatic mitochondrial dysfunction induced by fatty
acids and ethanol. Free Radic Biol Med. 53:2131–2145.
2012.PubMed/NCBI View Article : Google Scholar
|
|
62
|
Begriche K, Massart J, Robin MA,
Borgne-Sanchez A and Fromenty B: Drug-induced toxicity on
mitochondria and lipid metabolism: Mechanistic diversity and
deleterious consequences for the liver. J Hepatol. 54:773–794.
2011.PubMed/NCBI View Article : Google Scholar
|
|
63
|
Küper C, Beck FX and Neuhofer W: Toll-like
receptor 4 activates NF-κB and MAP kinase pathways to regulate
expression of proinflammatory COX-2 in renal medullary collecting
duct cells. Am J Physiol Renal Physiol. 302:F38–F46.
2012.PubMed/NCBI View Article : Google Scholar
|
|
64
|
Mardones M, Valenzuela R, Romanque P,
Covarrubias N, Anghileri F, Fernández V, Videla LA and Tapia G:
Prevention of liver ischemia reperfusion injury by a combined
thyroid hormone and fish oil protocol. J Nutr Biochem.
23:1113–1120. 2012.PubMed/NCBI View Article : Google Scholar
|
|
65
|
Valenzuela R, Illesca P, Echeverría F,
Espinosa A, Rincón-Cervera MÁ, Ortiz M, Hernandez-Rodas MC,
Valenzuela A and Videla LA: Molecular adaptations underlying the
beneficial effects of hydroxytyrosol in the pathogenic alterations
induced by a high-fat diet in mouse liver: PPAR-α and Nrf2
activation, and NF-κB down-regulation. Food Funct. 8:1526–1537.
2017.PubMed/NCBI View Article : Google Scholar
|
|
66
|
Sun J, Fu J, Zhong Y, Li L, Chen C, Wang
X, Wang L, Hou Y, Wang H, Zhao R, et al: NRF2 mitigates acute
alcohol-induced hepatic and pancreatic injury in mice. Food Chem
Toxicol. 121:495–503. 2018.PubMed/NCBI View Article : Google Scholar
|
|
67
|
Echeverría F, Valenzuela R, Bustamante A,
Álvarez D, Ortiz M, Soto-Alarcon SA, Muñoz P, Corbari A and Videla
LA: Attenuation of high-fat diet-induced rat liver oxidative stress
and steatosis by combined hydroxytyrosol-(HT-) eicosapentaenoic
acid supplementation mainly relies on HT. Oxid Med Cell Longev.
2018(5109503)2018.PubMed/NCBI View Article : Google Scholar
|
|
68
|
Barrera C, Valenzuela R, Rincón M,
Espinosa A, Echeverria F, Romero N, Gonzalez-Mañan D and Videla LA:
Molecular mechanisms related to the hepatoprotective effects of
antioxidant-rich extra virgin olive oil supplementation in rats
subjected to short-term iron administration. Free Radic Biol Med.
126:313–321. 2018.PubMed/NCBI View Article : Google Scholar
|
