Open Access

Primary pelvic exenteration: Our experience with 23 patients from a single institution

  • Authors:
    • Mihai Gheorghe
    • Alexandra Lavinia Cozlea
    • Szilard Leo Kiss
    • Mihai Stanca
    • Mihai Emil Căpîlna
    • Nicolae Bacalbașa
    • Andreea Anamaria Moldovan
  • View Affiliations

  • Published online on: July 26, 2021     https://doi.org/10.3892/etm.2021.10494
  • Article Number: 1060
  • Copyright: © Gheorghe et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

This study was designed with an aim to share our experience of primary pelvic exenterations. The study included 23 patients with different types of pelvic cancer enrolled at a single institution between November 2011 and July 2020. The patient mean age was 55 years (range, 43‑72 years) and the oncological indications included: Stage IVa cervical cancer (11 cases, 48.9%), stage IVa endometrial cancer (1 case, 4.3%), stage IVa vaginal cancer (6 cases, 26%), stage IIIb bladder cancer (3 cases, 13%), stage IIIc rectal cancer (1 case, 4.3%) and undifferentiated pelvic sarcoma (1 case, 4.3%). Total, anterior, and posterior pelvic exenterations were performed on 34.4, 56.5 and 13% of cases, respectively. Related to levator ani muscle, 13 (56.5%) pelvic exenterations were supralevatorian, 10 (43.5%) infralevatorian, and 5 (21.7%) were infralevatorian with vulvectomy. No major intraoperative complications occurred. Seven patients (30.5%) developed early complications, 4 of them (17.4%) required reoperation and 1 (4.3%) perioperative death caused by a pulmonary embolism was recorded. Only 1 patient experienced a late complication, a urostomy stenosis. Over a median follow‑up period of 35 months, 8 (34.8%) patients died. The median overall survival (OS) was 33 months (range, 1‑96 months). The 2‑year and 5‑year survival rates were 72 and 66%, respectively. Primary pelvic exenteration may be related with various postoperative complications, without high perioperative morality and with long‑term survival.
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October-2021
Volume 22 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Gheorghe M, Cozlea AL, Kiss SL, Stanca M, Căpîlna ME, Bacalbașa N and Moldovan AA: Primary pelvic exenteration: Our experience with 23 patients from a single institution. Exp Ther Med 22: 1060, 2021
APA
Gheorghe, M., Cozlea, A.L., Kiss, S.L., Stanca, M., Căpîlna, M.E., Bacalbașa, N., & Moldovan, A.A. (2021). Primary pelvic exenteration: Our experience with 23 patients from a single institution. Experimental and Therapeutic Medicine, 22, 1060. https://doi.org/10.3892/etm.2021.10494
MLA
Gheorghe, M., Cozlea, A. L., Kiss, S. L., Stanca, M., Căpîlna, M. E., Bacalbașa, N., Moldovan, A. A."Primary pelvic exenteration: Our experience with 23 patients from a single institution". Experimental and Therapeutic Medicine 22.4 (2021): 1060.
Chicago
Gheorghe, M., Cozlea, A. L., Kiss, S. L., Stanca, M., Căpîlna, M. E., Bacalbașa, N., Moldovan, A. A."Primary pelvic exenteration: Our experience with 23 patients from a single institution". Experimental and Therapeutic Medicine 22, no. 4 (2021): 1060. https://doi.org/10.3892/etm.2021.10494