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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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October-2021 Volume 22 Issue 4

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Impact Factor: 2.3

Article Open Access

The use of polypropylene mesh in inguinal hernia surgery: A retrospective study

Ciprian Tanasescu, Andrei Moisin, Alin Mihetiu, Dragos Serban, Adrian Costache, Dan Georgian Bratu
Article Number: 1193
Published online on: 17 August 2021

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Article Open Access

Axial and para‑axial loading response evaluation on human cadaver‑harvested lumbar vertebral blocks: In vitro experiment with possible clinical implications for clinical practice

Dan Marcel Iliescu, Sergiu-Ioan Micu, Costin Ionescu, Ionut Bulbuc, Petru Bordei, Bogdan Obada, Felix Voinea, Emma Gheorghe, Madalina Gabriela Iliescu
Article Number: 1192
Published online on: 17 August 2021

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Review

CLIPPERS, chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids: A challenge in neurological practice, clinical landmarks (Review)

Any Docu Axelerad, Alina Zorina Stroe, Cristina Mihai, Corina Frecus, Dragos Catalin Jianu, Daniel Docu Axelerad, Anca Elena Gogu
Article Number: 1191
Published online on: 17 August 2021

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Article Open Access

Rapamycin suppresses the PI3K/AKT/mTOR signaling pathway by targeting SIRT1 in esophageal cancer Retraction in /10.3892/etm.2023.12288

Tao Liu, Xiangsen Liang, Yu Sun, Shengzhuang Yang
Article Number: 1190
Published online on: 17 August 2021

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Article Open Access

Rosuvastatin protects PC12 cells from hypoxia/reoxygenation‑induced injury by inhibiting endoplasmic reticulum stress‑induced apoptosis

Yu Gao, Libo Li, Jianbai Yu, Zhanwei Zhang
Article Number: 1189
Published online on: 17 August 2021

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Article Open Access

Cell tracing reveals the transdifferentiation fate of mouse lung epithelial cells during pulmonary fibrosis in vivo

Wei Tan, Yaru Wang, Yuhua Chen, Cheng Chen
Article Number: 1188
Published online on: 17 August 2021

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Article Open Access

Effect of the acid suppressor omeprazole on the proliferation, migration, invasion and cell cycle of esophageal squamous cell carcinoma cells via the aryl hydrocarbon receptor pathway

Yu Bai, Peiyao Zhu, Kun Zhou, Shu-Guang Zhang
Article Number: 1187
Published online on: 17 August 2021

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Article Open Access

MicroRNA‑206 relieves irradiation‑induced neuroinflammation by regulating connexin 43

Wei Zeng, Li Fu, Hongfang Xu
Article Number: 1186
Published online on: 16 August 2021

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Article Open Access

Detection of mitochondrial coupling factor 6 in placental tissues from preeclamptic pregnancies and its influence on biological behavior of trophoblast cells

Wanyu Song, Xufeng Shi, Kan Liu, Ranhong Li, Leilei Niu, Lijun Su, Haiying Wu
Article Number: 1185
Published online on: 16 August 2021

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Article

Knockdown of LINC01123 inhibits cell viability, migration and invasion via miR‑361‑3p/TSPAN1 targeting in cervical cancer

Cui Li, Yujuan Li, Yuying Zhang, Hua Yan, Chengxiang Huang
Article Number: 1184
Published online on: 16 August 2021

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Case Report Open Access

Tuberous sclerosis with negative genetic testing and multiple cerebral cavernomas: A new association (Case report)

Anca Adriana Arbune, Basel Robert Toron, Ioan Cristian Lupescu, Ioana Gabriela Lupescu, Alin Laurentiu Tatu, Adriana Octaviana Dulamea
Article Number: 1183
Published online on: 16 August 2021

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Review Open Access

High‑dose intravenous immunoglobulins as a therapeutic option in critical illness polyneuropathy accompanying SARS‑CoV‑2 infection: A case‑based review of the literature (Review)

Adina Stoian, Zoltan Bajko, Smaranda Maier, Roxana Adriana Cioflinc, Bianca Liana Grigorescu, Anca Moțățăianu, Laura Bărcuțean, Rodica Balașa, Mircea Stoian
Article Number: 1182
Published online on: 16 August 2021

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Article Open Access

Propofol protects H9C2 cells against hypoxia/reoxygenation injury through miR‑449a and NR4A2

Qiu Qian, Yingxiang Xie
Article Number: 1181
Published online on: 16 August 2021

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Article Open Access

Understanding the molecular role of syndecan‑1 in the regulation of caspase‑6 during the progression of cardiac arrhythmia

Yuanchu Wu, Lin Chen, Caihong Wang
Article Number: 1180
Published online on: 16 August 2021

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Article Open Access

The new WHO classification of gastrointestinal neuroendocrine tumors and immunohistochemical expression of somatostatin receptor 2 and 5

Oana Popa, Sorina Maria Taban, Stelian Pantea, Andrei Dorel Plopeanu, Robert Alexandru Barna, Marioara Cornianu, Anca-Ariana Pascu, Alis Liliana Carmen Dema
Article Number: 1179
Published online on: 13 August 2021

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Review Open Access

Killer‑cell immunoglobulin‑like receptor/human leukocyte antigen‑C combination and ‘great obstetrical syndromes’ (Review)

Xiuhua Yang, Tao Meng
Article Number: 1178
Published online on: 13 August 2021

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Article Open Access

Cyclophosphamide inhibits the progression of Meniere's disease by reducing the generation of circulating immune complex

Shu Zhang, Yulin Gong, Yu Liang, Boqian Wang, Wei Gao, Qianyun Xu
Article Number: 1177
Published online on: 13 August 2021

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Article Open Access

Integrative analysis of miRNA‑mRNA expression profiles in esophageal fibrosis after ESD

Yin Zhang, Chunfang Xu
Article Number: 1176
Published online on: 13 August 2021

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Article Open Access

Piperazine ferulate prevents high‑glucose‑induced filtration barrier injury of glomerular endothelial cells

Yong-Yu Yang, Zhuo Chen, Xi-Ding Yang, Rong-Rong Deng, Ling-Xing Shi, Liang-Yuan Yao, Da-Xiong Xiang
Article Number: 1175
Published online on: 13 August 2021

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Article Open Access

Gardnerella vaginalis induces NLRP3 inflammasome‑mediated pyroptosis in macrophages and THP‑1 monocytes

Nan Xiang, Ting Yin, Tao Chen
Article Number: 1174
Published online on: 13 August 2021

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Article Open Access

Clinical efficiency of combination therapy using testosterone replacement therapy, phosphodiesterase 5 inhibitors and Kampo herbal medicine for eugonadal patients with late‑onset hypogonadism syndrome

Hisashi Takeuchi, Hidenori Okubo
Article Number: 1173
Published online on: 13 August 2021

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Article Open Access

MicroRNA‑124‑5p delays the progression of cerebral aneurysm by regulating FoxO1

Ru-Ke Wang, Yuan-Yuan Sun, Guang-You Li, Hua-Tang Yang, Xiu-Jie Liu, Ke-Feng Li, Xu Zhu, Guo-Yuan Yu
Article Number: 1172
Published online on: 13 August 2021

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Article

Osthole suppresses the proliferation and induces apoptosis via inhibiting the PI3K/AKT signaling pathway of endometrial cancer JEC cells

Lei Liang, Bo Yang, Yuanyuan Wu, Li Sun
Article Number: 1171
Published online on: 13 August 2021

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Article Open Access

In vitro assessment of the cytotoxicity and anti‑inflammatory properties of a novel dietary supplement

Ionela D. Popescu, Elena Codrici, Simona Mihai, Cristina-Mihaela Luntraru, Mihaela Neagu, Cristiana Tanase
Article Number: 1170
Published online on: 12 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑375 targets PAX6 and inhibits the viability, migration and invasion of human breast cancer MCF‑7 cells

Qiongyan Zou, Wenjun Yi, Jianghai Huang, Fenfen Fu, Gannong Chen, Dewu Zhong
Article Number: 1169
Published online on: 12 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑137 acts as a tumor suppressor in osteosarcoma by targeting enhancer of zeste homolog 2

Qiong Feng, Qing Wu, Xing Liu, Yanfei Xiong, Hui Li
Article Number: 1168
Published online on: 12 August 2021

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Review Open Access

Future perspectives in diabesity treatment: Semaglutide, a glucagon‑like peptide 1 receptor agonist (Review)

Mariana Cornelia Tilinca, Robert Aurelian Tiuca, Cristina Niculas, Andreea Varga, Ioan Tilea
Article Number: 1167
Published online on: 12 August 2021

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Article Open Access

Construction and evaluation of a novel tissue‑engineered bone device

Zhengqi Chang, Junchao Xing, Xiuchun Yu
Article Number: 1166
Published online on: 12 August 2021

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Article Open Access

Angiotensin‑converting enzyme 2 alleviates pulmonary artery hypertension through inhibition of focal adhesion kinase expression

Rui Wang, Jingjing Xu, Jinbo Wu, Shunheng Gao, Zhiping Wang
Article Number: 1165
Published online on: 12 August 2021

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Article Open Access

Autophagy positively regulates Wnt signaling in mice with diabetic retinopathy

Sihao Ye, Yuhan Zhang, Xin Wang, Xu Liang, Mingyan Wei, Rongrong Zong, Zuguo Liu, Qian Chen
Article Number: 1164
Published online on: 12 August 2021

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Article Open Access

miR‑184 delays cell proliferation, migration and invasion in prostate cancer by directly suppressing DLX1

Gui-Geng Tan, Chang Xu, Wei-Kang Zhong, Chuan-Yun Wang
Article Number: 1163
Published online on: 11 August 2021

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Review Open Access

COVID‑19 and post‑traumatic stress disorder: The perfect ‘storm’ for mental health (Review)

Ioanna Giannopoulou, Sofia Galinaki, Evangelia Kollintza, Maria Adamaki, Stylianos Kympouropoulos, Evangelos Alevyzakis, Konstantinos Tsamakis, Iraklis Tsangaris, Demetrios A. Spandidos, Nikolaos Siafakas, Vassilios Zoumpourlis, Emmanouil Rizos
Article Number: 1162
Published online on: 11 August 2021

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Review Open Access

Molecular mechanisms in septic shock (Review)

Gabriel Gorecki, Daniel Cochior, Cosmin Moldovan, Elena Rusu
Article Number: 1161
Published online on: 11 August 2021

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Article

Long non‑coding RNA HOTAIR knockdown alleviates lipopolysaccharide‑induced acute respiratory distress syndrome and the associated inflammatory response by modulating the microRNA‑30a‑5p/PDE7A axis

Hongrong Wang, Shasha Song, Xianyu Mu
Article Number: 1160
Published online on: 11 August 2021

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Review

Crosstalk of fibroblast growth factor 23 and anemia‑related factors during the development and progression of CKD (Review)

Rui Zhang, Song-Yan Wang, Fan Yang, Shuang Ma, Xu Lu, Chao Kan, Jing-Bin Zhang
Article Number: 1159
Published online on: 11 August 2021

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Case Report

Basal cell carcinoma‑not always the ‘good guy’: Case report of a life‑threatening basosquamous carcinoma and review of the literature

Cornel Adrian Petreanu, Elena-Daniela Șerban, Maria-Magdalena Constantin, Cornel Savu, Alexandru Victor Zariosu, Oana Claudia Deleanu, Stefana Bucur, Traian Constantin
Article Number: 1158
Published online on: 10 August 2021

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Article

Upregulation of miR‑144‑3p expression attenuates glioma cell viability and invasion by targeting BCL6

Jingru Zhou, Ruen Liu
Article Number: 1157
Published online on: 10 August 2021

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Article

A novel therapy for granulomatous lobular mastitis: Local heat therapy

Xinxin Chen, Wangjian Zhang, Qiuer Yuan, Xiaowu Hu, Ting Xia, Tengfei Cao, Haixia Jia, Lehong Zhang
Article Number: 1156
Published online on: 10 August 2021

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Article Open Access

circASS1 overexpression inhibits the proliferation, invasion and migration of colorectal cancer cells by regulating the miR‑1269a/VASH1 axis

Hai-Lin Xiong, Xiao-Hua Zhong, Xiao-Hong Guo, Hao-Jie Liao, Xia Yuan
Article Number: 1155
Published online on: 10 August 2021

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Article Open Access

ASPM combined with KIF11 promotes the malignant progression of hepatocellular carcinoma via the Wnt/β‑catenin signaling pathway

Bin Wu, Chunyang Hu, Lianbao Kong
Article Number: 1154
Published online on: 10 August 2021

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Article Open Access

lncRNA MEG8 is downregulated in osteoarthritis and regulates chondrocyte cell proliferation, apoptosis and inflammation

Wei Xie, Luoyong Jiang, Xiaoyang Huang, Hongxi Shang, Minghong Gao, Wei You, Jifeng Tan, Hong Yan, Wei Sun
Article Number: 1153
Published online on: 10 August 2021

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Article Open Access

Deacetylated Sp1 improves β‑glycerophosphate‑induced calcification in vascular smooth muscle cells

Zihao Zhang, Xinyu Zhang, Chengwei Wang, Peng Zhou, Jie Xiao, Hui Zheng, Lei Wang, Senbo Yan, Yue Zhang, Xiaoping Ji
Article Number: 1152
Published online on: 10 August 2021

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Article Open Access

Decreased expression of miR‑3135b reduces sensitivity to 5‑fluorouracil in colorectal cancer by direct repression of PIM1

Yan Wang, Xiaofeng Cui, Shurong Ma, Haishan Zhang
Article Number: 1151
Published online on: 10 August 2021

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Review

How specific molecular‑targeted agents can make obsolete a ‘one size fits all’ approach in EGFR‑mutated NSCLC treatment (Review)

Carmen Popescu, Laura Mazilu, Andra-Iulia Suceveanu, Alexandru Grigorescu
Article Number: 1150
Published online on: 10 August 2021

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Review Open Access

Emerging deep learning techniques using magnetic resonance imaging data applied in multiple sclerosis and clinical isolated syndrome patients (Review)

Eleftherios E. Kontopodis, Efrosini Papadaki, Eleftherios Trivizakis, Thomas G. Maris, Panagiotis Simos, Georgios Z. Papadakis, Aristidis Tsatsakis, Demetrios A. Spandidos, Apostolos Karantanas, Kostas Marias
Article Number: 1149
Published online on: 09 August 2021

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Article Open Access

Long non‑coding RNA SNHG1 relieves microglia activation by downregulating miR‑329‑3p expression in an in vitro model of cerebral infarction

Jianli He, Xianjun Xuan, Minhai Jiang, Jiangtao Li, Ning Li, Tian Nie
Article Number: 1148
Published online on: 09 August 2021

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Article Open Access

Role of Helicobacter pylori in the triggering and evolution of hemorrhagic gastro‑duodenal lesions

Dragos George Popa, Cosmin Vasile Obleagă, Bogdan Socea, Dragos Serban, Marius Eugen Ciurea, Marian Diaconescu, Ionică Daniel Vîlcea, Cristian Meșină, Cecil Mirea, Dan Nicolae Florescu, Vlad Dumitru Baleanu, Meda Comandasu, Mihai Silviu Tudosie, Laura Carina Tribus, Bogdan Niculescu
Article Number: 1147
Published online on: 09 August 2021

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Article Open Access

Latent‑transforming growth factor β‑binding protein 2 accelerates cardiac fibroblast apoptosis by regulating the expression and activity of caspase‑3

Chunlai Shi, Xuan Li, Fei Hong, Xueyan Wang, Tingting Jiang, Bingbing Sun, Shuang Li
Article Number: 1146
Published online on: 09 August 2021

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Case Report Open Access

Primary amyloidosis involving the gastrointestinal tract, mesentery and omentum: A case report

Guihua Duan, Min Qi, Qiang Guo, Zhengji Song
Article Number: 1145
Published online on: 09 August 2021

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Article Open Access

Preparation of docetaxel‑loaded, glycyrrhetinic acid‑modified nanoparticles and their liver‑targeting and antitumor activity

Hantao Xue, Liya Qin, Longxiang Zhang, Xiaocheng Li, Fei Wu, Weiyu Wang, Chen Wang, Wenbin Diao, Bin Jiang, Bo Lian, Jingliang Wu, Jingkun Bai, Tongyi Sun, Chunling Zhao, Meihua Qu, Wenjing Yu, Yubing Wang, Zhiqin Gao
Article Number: 1144
Published online on: 09 August 2021

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Article Open Access

Gadolinium chloride pre‑treatment reduces the inflammatory response and preserves intestinal barrier function in a rat model of sepsis

Yan Heng Zhao, Shun Wen Zhang, Hai Jun Zhao, Hui Yuan Qin, Fang Wu, Jie Zhang, Yu Qing Zhang, Xiao Ling Liu, Su Liang, Hui Zhang, Jiang Dong Wu, Zheng Yong Zhao, Hong Zhou Wang, Meng Shao, Jing Liu, Jiang Tao Dong, Wan Jiang Zhang
Article Number: 1143
Published online on: 09 August 2021

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Article

Knockdown of LINC00657 inhibits the viability, migration and invasion of pancreatic cancer cells by regulating the miR‑520h/CKS1B axis

Peng Li, Hongsheng Wang, Ying Tang, Shuo Sun, Yue Ma, Yansong Xu, Guangyu Chen
Article Number: 1142
Published online on: 09 August 2021

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Article Open Access

Risk factors associated with intra‑stent restenosis after percutaneous coronary intervention

Dan-Mihai Alexandrescu, Ovidiu Mitu, Irina Iuliana Costache, Liviu Macovei, Ivona Mitu, Anca Alexandrescu, Catalina Arsenescu Georgescu
Article Number: 1141
Published online on: 09 August 2021

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Article Open Access

Clinical prognostic value of circulating tumor cells in the treatment of pancreatic cancer with gemcitabine chemotherapy

Xiaoguang Wang, Lingyu Hu, Xiaodan Yang, Fei Chen, Haokai Xu, Haitao Yu, Zhengwei Song, Jianguo Fei, Zhengxiang Zhong
Article Number: 1140
Published online on: 08 August 2021

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Article Open Access

C1q/TNF‑related protein 9 decreases cardiomyocyte hypoxia/reoxygenation‑induced inflammation by inhibiting the TLR4/MyD88/NF‑κB signaling pathway

Zhongyi Huang, Dan Zhao, Yongjian Wang, Xiaolei Li, Jianqiu Li, Jie Han, Lisi Jiang, Fen Ai, Zhaoxiong Zhou
Article Number: 1139
Published online on: 08 August 2021

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Article Open Access

Periplaneta americana extract ameliorates lipopolysaccharide‑induced liver injury by improving mitochondrial dysfunction via the AMPK/PGC‑1α signaling pathway

Wei Shi, Li An, Jun Zhang, Jie Li
Article Number: 1138
Published online on: 08 August 2021

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Article Open Access

Role of lncRNA BCYRN1 in trophoblast cell physiology and pathogenesis of preeclampsia

Liping Chen, Qi Shi, Bo Fan, Yan Cai
Article Number: 1137
Published online on: 06 August 2021

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Article Open Access

lncRNA and mRNA sequencing of the left testis in experimental varicocele rats treated with Morinda officinalis polysaccharide

Lihong Zhang, Xiaozhen Zhao, Wei Wang
Article Number: 1136
Published online on: 06 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑9 inhibits the proliferation and migration of malignant melanoma cells via targeting sirituin 1

Pingyuan Bu, Chengqun Luo, Quanyong He, Ping Yang, Xi Li, Dan Xu
Article Number: 1135
Published online on: 06 August 2021

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Retraction Open Access

[Retracted] MiR‑203 inhibits estrogen‑induced viability, migration and invasion of estrogen receptor α‑positive breast cancer cells

Jun Lin, Li Wang, Jie Gao, Shiguang Zhu
Article Number: 1134
Published online on: 06 August 2021

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Article Open Access

MicroRNA‑221 regulates cell activity and apoptosis in acute lymphoblastic leukemia via regulating PTEN

Lingyan Zhang, Zibin Bu, Juan Shen, Liping Shang, Yuanyuan Chen, Ping Zhang, Yan Wang
Article Number: 1133
Published online on: 06 August 2021

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Review Open Access

Korsakoff syndrome: An overlook (Review)

Ionuţ Popa, Ioana Rădulescu, Ana Miruna Drăgoi, Simona Trifu, Mihai Bogdan Cristea
Article Number: 1132
Published online on: 05 August 2021

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Review Open Access

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Atanasio Pandiella, Eduardo Sanz, Elena Díaz‑Rodríguez
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Yang Fu, Liying Luo, Ying Fan, Min Tang
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Biao Tang, Xu She, Chang-Qing Deng
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Ping Chen, Yusheng Li, Li Xiao
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Jing Yang, Xiaoli Xie
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Xiaoning Wang, Weiwei Lu, Bing Liu, Yunhe Xu
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Chenggang Cao, Xiaolei Shu
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Caterina Maria Grillo, Luigi Maiolino, Agnese Maria Chiara Rapisarda, Giuseppe Caruso, Gaia Palermo, Salvatore Caruso
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Jin Peng, Xijiang Liu, Chengcheng Li, Min Gao, Hongyan Wang
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Ran Li, Li Jiang, Xiaoling Wang
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PTEN downregulation induces apoptosis and cell cycle arrest in uterine cervical cancer cells

Jin Woo Shin, Se-Hee Kim, Jin Young Yoon
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Magnetic resonance imaging of brain anomalies in adult and pediatric schizophrenia patients: Experience of a Romanian tertiary hospital

Floris Petru Iliuta, Mihnea Costin Manea, Magdalena Budisteanu, Emanuela Andrei, Florentina Linca, Florina Rad, Romica Cergan, Adela Magdalena Ciobanu
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β‑elemene inhibits non‑small cell lung cancer cell migration and invasion by inactivating the FAK‑Src pathway

Hongbo Zhang, Shaobing Li, Jun Bao, Ning Ge, Fu Hong, Liting Qian
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KIF2C promotes the proliferation of hepatocellular carcinoma cells in vitro and in vivo Retraction in /10.3892/etm.2023.12095

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Knockdown of ALDH1A3 reduces breast cancer stem cell marker CD44 via the miR‑7‑TGFBR2‑Smad3‑CD44 regulatory axis

Meng Pan, Miao Li, Mei Guo, Huiying Zhou, Hui Xu, Fengshu Zhao, Feng Mei, Rui Xue, Jun Dou
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The designed NF‑κB inhibitor, DHMEQ, inhibits KISS1R‑mediated invasion and increases drug‑sensitivity in mouse plasmacytoma SP2/0 cells

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Osteogenic ability using porous hydroxyapatite scaffold‑based delivery of human placenta‑derived mesenchymal stem cells

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[Retracted] MicroRNA‑19a promotes nasopharyngeal carcinoma by targeting transforming growth factor β receptor 2

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IL‑22 alleviates the fibrosis of hepatic stellate cells via the inactivation of NLRP3 inflammasome signaling

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Insights into multidrug‑resistant K. pneumoniae urinary tract infections: From susceptibility to mortality

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Benazepril hydrochloride protects against doxorubicin cardiotoxicity by regulating the PI3K/Akt pathway

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Herbal melanin induces interleukin‑1β secretion and production by human THP‑1 monocytes via Toll‑like receptor 2 and p38 MAPK activation

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Effect of erythropoietin on angiogenic potential of dental pulp cells

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MicroRNA‑195‑5p suppresses the proliferation, migration, invasion and epithelial‑mesenchymal transition of laryngeal cancer cells in vitro by targeting E2F3

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Astragaloside IV alleviates heart failure by regulating SUMO‑specific protease 1 Corrigendum in /10.3892/etm.2023.12021

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Emodin inhibits the proliferation of papillary thyroid carcinoma by activating AMPK

Weilong Li, Dong Wang, Meijing Li, Baoyuan Li
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Protectin D1 protects against lipopolysaccharide‑induced acute lung injury through inhibition of neutrophil infiltration and the formation of neutrophil extracellular traps in lung tissue

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Clinical efficacy of repeated intra‑articular pulsed radiofrequency for the treatment of knee joint pain and its effects on inflammatory cytokines in synovial fluid of patients

Jie Zhao, Zhenyue Wang, Huaibao Xue, Zhan Yang
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Fumaric acid and succinic acid treat gestational hypertension by downregulating the expression of KCNMB1 and TET1

Yiyuan Zhou, Fang Zhang, Huijiao Jiang, Di Xu, Dongyang Deng
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Xiaoya Gao, Yun Xue, Kechun Yang
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A steroid‑induced osteonecrosis model established using an organ‑on‑a‑chip platform

Tengqi Li, Yadi Liu, Qingyu Zhang, Wei Sun, Yiyang Dong
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Risk of sudden coronary death based on genetic background in Chinese Han population

Nenghua Zhang, Xiaochun Lv, Xiaojuan Cheng, Jiaqi Wang, Jinding Liu, Jie Shi, Jie Liu, Bo Hu, Deqing Chen, Gengqian Zhang
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A survey to assess the incidence of Down syndrome risk in rural southwestern Romania

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Roxana-Maria Talpos‑Niculescu, Luminita-Maria Nica, Malina Popa, Serban Talpos‑Niculescu, Laura Cristina Rusu
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Omega plate for the treatment of acetabular fractures involving the quadrilateral plate

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A multidisciplinary approach in the diagnostic challenge of GIST

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Ovidiu Nicolae Berghi, Daniela Vrinceanu, Romica Cergan, Mihai Dumitru, Adrian Costache
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Primary pelvic exenteration: Our experience with 23 patients from a single institution

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MicroRNA‑139‑5p improves sepsis‑induced lung injury by targeting Rho‑kinase1

Xinmin Zhao, Mengmeng Wang, Zhaorui Sun, Suyuan Zhuang, Wei Zhang, Zhizhou Yang, Xiaoqin Han, Shinan Nie
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Establishment of incontinence‑associated dermatitis rat models and assessment of the therapeutic effects of zinc oxide, painless skin protective film and silicone dressing

Guiyuan Chen, Liquan Huang, Yingxun Chen, Shufeng Zheng, Louying Zhu, Mingxing Ding
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Effects of the p16/cyclin D1/CDK4/Rb/E2F1 pathway on aberrant lung fibroblast proliferation in neonatal rats exposed to hyperoxia

Shimeng Zhao, Zhiguang Chen, Shuang Han, Hongmin Wu
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Bilirubin is a specific marker for the diagnosis of acute appendicitis

Dimitrios Zosimas, Panagis M. Lykoudis, Giuseppe Strano, Josh  Burke, Eyad Al‑Cerhan, Veeranna Shatkar
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Fas regulates the apoptosis and migration of trophoblast cells by targeting NF‑κB

Ruihong Lan, Yang Yang, Jie Song, Ling Wang, Humin Gong
Article Number: 1055
Published online on: 23 July 2021

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Inhibition of autophagy promotes human RSV NS1‑induced inflammation and apoptosis in vitro

Bing Han, Yizhong Wang, Mei Zheng
Article Number: 1054
Published online on: 23 July 2021

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NEIL3 contributes toward the carcinogenesis of liver cancer and regulates PI3K/Akt/mTOR signaling

Weichen Wang, Qing Yin, Shanshan Guo, Jun Wang
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IL‑17F promotes osteoblastic osteogenesis via the MAPK/ERK1/2 signaling pathway

Na Zhang, Min Cui, Xudong Liu, Lingzhi Yu, Xu Zhao, Luning Cao, Yuanyuan Ji
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IKKε knockout alleviates angiotensin II‑induced apoptosis and excessive autophagy in vascular smooth muscle cells by regulating the ERK1/2 pathway

Ganyi Chen, Yueyue Xu, Yiwei Yao, Yide Cao, Yafeng Liu, Hao Chai, Wen Chen, Xin Chen
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Network pharmacology‑based prediction of the active compounds and mechanism of Buyang Huanwu Decoction for ischemic stroke

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Anti‑inflammatory effects of miR‑150 are associated with the downregulation of STAT1 in macrophages following lipopolysaccharide treatment

Song Chen, Haijun Zhu, Jie Sun, Lili Zhu, Long Qin, Jian Wan
Article Number: 1049
Published online on: 23 July 2021

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CGFe and TGF‑β1 enhance viability and osteogenic differentiation of human dental pulp stem cells through the MAPK pathway

Xiaoju Li, Huixiao Yang, Yan Zhang, Xinya Du, Zhengbin Yan, Jiang Li, Bin Wu
Article Number: 1048
Published online on: 23 July 2021

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Inhibition of miR‑483‑5p improves the proliferation, invasion and inflammatory response of triple‑negative breast cancer cells by targeting SOCS3

Jianbo Ren, Gang Xu, Hongyan Sun, Ting Lin, Sanhui Xu, Yating Zhao
Article Number: 1047
Published online on: 22 July 2021

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Dexmedetomidine alleviates inflammation in neuropathic pain by suppressing NLRP3 via Nrf2 activation

Wenyan Shan, Xiaoyun Liao, Yixun Tang, Jitong Liu
Article Number: 1046
Published online on: 22 July 2021

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Aloperine protects against cerebral ischemia/reperfusion injury via activating the PI3K/AKT signaling pathway in rats

Zhimin Li, Xing Cao, Ligen Xiao, Ruijiao Zhou
Article Number: 1045
Published online on: 22 July 2021

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Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
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Published online on: 19 November 2025

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Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

Shengbin Han, Jingzhe Xu, Chenchen Yu, Hongxi Guan, Shun Ding
Article Number: 24
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 23
Published online on: 17 November 2025

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Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

Jinqi Yan, Xiaohu Wang, Chen Liang
Article Number: 22
Published online on: 14 November 2025

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Review Open Access

Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

Mingxin He, Feng Chen, Xiaomin Xian, Zhi Guo
Article Number: 21
Published online on: 14 November 2025

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Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

Yunching Lai, Xiaolei Chen, Hebing Zhou
Article Number: 20
Published online on: 10 November 2025

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Case Report Open Access

Diagnostic challenge of aneurysmal dermatofibroma mimicking cutaneous metastasis in a patient with lung cancer: A case report

Jong Yun Choi, Heeyang Park, Jangyoun Choi
Article Number: 19
Published online on: 10 November 2025

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Retraction Open Access

[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Article Number: 18
Published online on: 10 November 2025

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Article

Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study

Jeng-Yuan Yao, De-Tian-Yu Tzeng, Cai-Hong Feng, Gong-Man Xiao, Tian-Ni You, Ru-Yu Zheng
Article Number: 17
Published online on: 06 November 2025

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Case Report Open Access

Chronic maxillary sinusitis masquerading as a maxillary sinus neoplasm: A case report

Ji-Hyeon Oh, Seong-Gon Kim, Su-Young Kim
Article Number: 16
Published online on: 04 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
Article Number: 15
Published online on: 04 November 2025

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Article Open Access

A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

Jingqiao Li, Yipeng Yang, Xu Zhang, Dandan Zhang, Yadong Yu, Rong Chen, Wei Du
Article Number: 14
Published online on: 30 October 2025

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Case Report Open Access

Primary epithelioid angiomatous nodule of the vocal cord: A case report and literature review

Keda Li, Bin Huang, Lubing Cai, Mingqi Huang, Jianping Shi, Mingdi Jin, Ning Qian, Yongkang Guo
Article Number: 13
Published online on: 29 October 2025

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Case Report Open Access

Hepatic perivascular epithelioid cell tumor: A rare mesenchymal tumor with epithelioid features: A case report

Mahmoud Abbas, Benjamin Strücker, Mehmet Haluk Morgül, Andreas Pascher, Wolfgang Hartmann, Eva Wardelmann
Article Number: 12
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet

Lei Huang, Chao Ding, Xinmin Si
Article Number: 11
Published online on: 29 October 2025

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Article

Evaluation of total oxidant status/total antioxidant capacity and DNA damage in neonates with high lactate levels in umbilical cord blood gases

Burcu Cebeci, Aydemir Yalvaç, Derya Büyükkayhan, Dilek Kurnaz, Hakan Çakir, Murat Elevli
Article Number: 10
Published online on: 29 October 2025

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Case Report

Treatment of a mandibular molar with primary failure of eruption: A case report

Ming Guo, Weisheng Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

Effect of the water‑soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells

Xinghuanyu Xu, Lin Liu, Wenbai Zhang, Pu Xu
Article Number: 8
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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Retraction Open Access

[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

Xiao Ma, Jingjing Ma, Han Zhang, Xiaodong Jia, Tianrui Wang, Shanshan Ma, Yingze Zhang
Article Number: 4
Published online on: 21 October 2025

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Epimedin C: A promising neuroprotective agent that can participate in mediating the JNK/Nrf2/HO‑1 signaling pathway to prevent neurodegenerative diseases

Chao Cong, Xuan-Ling Li, Guang-Yao Lin, Lian-Wei Xu
Article Number: 3
Published online on: 21 October 2025

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Application of pleural effusion cell blocks for immunohistochemistry and EGFR gene mutation testing for advanced lung cancer

Shouxiang Zhao, Yuhong Liu, Tao Wang, Ying Li, Ze Chen, Xiaoshan Cai
Article Number: 2
Published online on: 21 October 2025

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Correction Open Access

[Corrigendum] Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility in vitro

Huan Wang, Tingtao Chen, Yidan Chen, Tao Luo, Buzhen Tan, Houyang Chen, Hongbo Xin
Article Number: 1
Published online on: 16 October 2025

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February-2026 Volume 31 Issue 2

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Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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