|
1
|
Prota G: Regulatory mechanisms of
melanogenesis: Beyond the tyrosinase concept. J Invest Dermatol.
100 (Suppl 2):156S–161S. 1993.PubMed/NCBI
|
|
2
|
Riley P: Molecules in focus: Melanin. Int
J Biochem Cell Biol. 29:1235–1239. 1997.
|
|
3
|
Bell AA: Biochemical mechanisms of disease
resistance. Ann Rev Plant Physiol. 32:21–81. 1981.
|
|
4
|
Rosas ÁL, MacGill RS, Nosanchuk JD, Kozel
TR and Casadevall A: Activation of the alternative complement
pathway by fungal melanins. Clin Diagn Lab Immunol. 9:144–148.
2002.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Freitak D, Vanatoa A, Ots I and Rantala
MJ: Formation of melanin-based wing patterns is influenced by
condition and immune challenge in Pieris brassicae. Entomol
Exp et Applicata. 116:237–243. 2005.
|
|
6
|
Pugh ND, Balachandran P, Lata H, Dayan FE,
Joshi V, Bedir E, Makino T, Moraes R, Khan I and Pasco DS: Melanin:
Dietary mucosal immune modulator from Echinacea and other
botanical supplements. Int Immunopharmacol. 5:637–647.
2005.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Haq A, Lobo PI, Al-Tufail M, Rama NR and
Al-Sedairy ST: Immunomodulatory effect of Nigella sativa
proteins fractionated by ion exchange chromatography. Int J
Immunopharmacol. 21:283–295. 1999.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Islam SN, Begum P, Ahsan T, Huque S and
Ahsan M: Immunosuppressive and cytotoxic properties of Nigella
sativa. Phytother Res. 18:395–398. 2004.PubMed/NCBI View
Article : Google Scholar
|
|
9
|
Hassib A: Extraction of melanin from
Nigella sativa L. Patent no. 451. Khartoum, Sudan, 1998.
|
|
10
|
El-Obeid A, Al-Harbi S, Al-Jomah N and
Hassib A: Herbal melanin modulates tumor necrosis factor alpha
(TNF-alpha), interleukin 6 (IL-6. and vascular endothelial growth
factor (VEGF). production. Phytomedicine. 13:324–333.
2006.PubMed/NCBI View Article : Google Scholar
|
|
11
|
El-Obeid A, Hassib A, Pontén F and
Westermark B: Effect of herbal melanin on IL-8: A possible role of
Toll-like receptor 4 (TLR4). Biochem Biophys Res Commun.
344:1200–1206. 2006.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Oberg F, Haseeb A, Ahnfelt M, Pontén F,
Westermark B and El-Obeid A: Herbal melanin activates
TLR4/NF-kappaB signaling pathway. Phytomedicine. 16:477–484.
2009.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Madej MP, Töpfer E, Boraschi D and
Italiani P: Different regulation of interleukin-1 production and
activity in monocytes and macrophages: Innate memory as an
endogenous mechanism of IL-1 inhibition. Front Pharmacol.
8(335)2017.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Dinarello CA: Overview of the IL-1 family
in innate inflammation and acquired immunity. Immunol Rev.
281:8–27. 2018.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Semino C, Carta S, Gattorno M, Sitia R and
Rubartelli A: Progressive waves of IL-1b release by primary human
monocytes via sequential activation of vesicular and gasdermin
D-mediated secretory pathways. Cell Death Dis.
9(1088)2018.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Shen J, Xu S, Zhou H, Liu H, Jiang W, Hao
J and Hu Z: IL-1β induces apoptosis and autophagy via mitochondria
pathway in human degenerative nucleus pulposus cells. Sci Rep.
7(41067)2017.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Baker KJ, Houston A and Brint E: IL-1
family members in cancer; two sides to every story. Front Immunol.
10(1197)2019.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Coutinho LG, Grandgirard D, Leib SL and
Agnez-Lima LF: Cerebrospinal-fluid cytokine and chemokine profile
in patients with pneumococcal and meningococcal meningitis. BMC
Infect Dis. 13(326)2013.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Thobakgale C and Naidoo K, McKinnon LR,
Werner LR, Werner L, Samsunder N, Karim SA, Ndung'u T, Altfeld M
and Naidoo K: Interleukin 1-beta (IL-1β) production by innate cells
following TLR stimulation correlates with TB recurrence in
ART-treated HIV-infected patients. J Acquir Immune Defic Syndr.
74:213–220. 2017.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Kawasaki T and Kawai T: Toll-like receptor
signaling pathways. Front Immunol. 5(461)2014.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Molteni M, Bosi A and Rossetti C: Natural
products with Toll-like receptor 4 antagonist activity. Int J
Inflam. 2018(2859135)2018.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Raby AC, González-Mateo GT, Williams A,
Topley N, Fraser D, López-Cabrera M and Labéta MO: Targeting
Toll-like receptors with soluble Toll-like receptor 2 prevents
peritoneal dialysis solution-induced fibrosis. Kidney Int.
94:346–362. 2018.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Zhang G and Ghosh S: Toll-like
receptor-mediated NF-kappaB activation: A phylogenetically
conserved paradigm in innate immunity. J Clin Invest. 107:13–19.
2001.PubMed/NCBI View
Article : Google Scholar
|
|
24
|
Liu YX, Wang GD, Wang X, Zhang YL and
Zhang TL: Effects of TLR-2/NF-κB signaling pathway on the
occurrence of degenerative knee osteoarthritis: An in vivo and in
vitro study. Oncotarget. 8:38602–38617. 2017.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Zheng DY, Zhou M, Jin J, He M, Wang Y, Du
J, Xiao XY, Li PY, Ye AZ, Liu J and Wang TH: Inhibition of P38 MAPK
downregulates the expression of IL-1β to protect lung from acute
injury in intestinal ischemia reperfusion rats. Mediators Inflamm.
2016(9348037)2016.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Matou-Nasri S, Rhaban Z, Al-Baijan H,
Al-Eidi H, Yahya WB, Al Abdulrahman A, Almobadel N, Alsubeai M, Al
Ghamdi S, Alaskar A, et al: CD95-mediated apoptosis in Burkitt's
lymphoma B-cells is associated with Pim-1 down-regulation. Biochim
Biophys Acta Mol Basis Dis. 1863:239–252. 2017.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Jablonska E and Marcinczyk M: TLR2
expression in relation to IL-6 and IL-1 beta and their natural
regulators production by PMN and PBMC in patients with Lyme
disease. Mediators Inflamm. 2006(32071)2006.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Goral J and Kovacs EJ: In vivo ethanol
exposure down-regulates TLR2-, TLR4-, and TLR9-mediated macrophage
inflammatory response by limiting p38 and ERK1/2 activation. J
Immunol. 174:456–463. 2005.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Jin J, Samuvel DJ, Zhang X, Li Y, Lu Z,
Lopes-Virella MF and Huang Y: Coactivation of TLR4 and TLR2/6
coordinates an additive augmentation on IL-6 gene transcription via
p38MAPK pathway in U937 mononuclear cells. Mol Immunol. 49:423–432.
2011.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Auron PE and Webb AC: Interleukin-1: A
gene expression system regulated at multiple levels. Eur Cytokine
Netw. 5:573–592. 1994.PubMed/NCBI
|
|
31
|
Eggesbø JB, Hjermann I, Lund PK, Joø GB,
Ovstebø R and Kierulf P: LPS-induced release of IL-1 beta, IL-6,
IL-8, TNF-alpha and sCD14 in whole blood and PBMC from persons with
high or low levels of HDL-lipoprotein. Cytokine. 6:521–529.
1994.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Harrison LM, van den Hoogen C, van Haaften
WC and Tesh VL: Chemokine expression in the monocytic cell line
THP-1 in response to purified shiga toxin 1 and/or
lipopolysaccharides. Infect Immun. 73:403–412. 2005.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Murphy M, Xiong Y, Pattabiraman G, Qiu F
and Medvedev AE: Pellino-1 positively regulates Toll-like receptor
(TLR) 2 and TLR4 signaling and is suppressed upon induction of
endotoxin tolerance. J Biol Chem. 290:19218–19232. 2015.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Karwaciak I, Gorkiewicz M, Bartosz G and
Pulaski L: TLR2 activation induces antioxidant defence in human
monocyte-macrophage cell line models. Oncotarget. 8:54243–54264.
2017.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Mohagheghpour N, Waleh N, Garger SJ,
Dousman L, Grill LK and Tusé D: Synthetic melanin suppresses
production of proinflammatory cytokines. Cell Immunol. 199:25–36.
2000.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Liu Y, Wang Y, Yamakuchi M, Isowaki S,
Nagata E, Kanmura Y, Kitajima I and Maruyama I: Upregulation of
Toll-like receptor 2 gene expression in macrophage response to
peptidoglycan and high concentration of lipopolysaccharide is
involved in NF-kappaB activation. Infect Immun. 69:2788–2796.
2001.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Wan J, Shan Y, Fan Y, Fan C, Chen S, Sun
J, Zhu L, Qin L, Yu M and Lin Z: NF-κB inhibition attenuates
LPS-induced TLR4 activation in monocyte cells. Mol Med Rep.
14:4505–4510. 2016.PubMed/NCBI View Article : Google Scholar
|
|
38
|
El-Obeid A, Alajmi H, Harbi M, Yahya WB,
Al-Eidi H, Alaujan M, Haseeb A, Trivilegio T, Alhallaj A, Alghamdi
S, et al: Distinct anti-proliferative effects of herbal melanin on
human acute monocytic leukemia THP-1 cells and embryonic kidney
HEK293 cells. BMC Complement Med Ther. 20(154)2020.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Ibrahim H, Barrow P and Foster N:
Transcriptional modulation by VIP: A rational target against
inflammatory disease. Clin Epigenetics. 2:213–222. 2011.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Peroval MY, Boyd AC, Young JR and Smith
AL: A critical role for MAPK signalling pathways in the
transcriptional regulation of Toll like receptors. PLoS One.
8(e51243)2013.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Li JY, Liu Y, Gao XX, Gao X and Cai H:
TLR2 and TLR4 signaling pathways are required for recombinant
Brucella abortus BCSP31-induced cytokine production, functional
upregulation of mouse macrophages, and the Th1 immune response in
vivo and in vitro. Cell Mol Immunol. 11:477–494. 2014.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Mukherjee S, Karmakar S and Babu SP: TLR2
and TLR4 mediated host immune responses in major infectious
diseases: A review. Braz J Infect Dis. 20:193–204. 2016.PubMed/NCBI View Article : Google Scholar
|
