Open Access

Magnetic resonance imaging of brain anomalies in adult and pediatric schizophrenia patients: Experience of a Romanian tertiary hospital

  • Authors:
    • Floris Petru Iliuta
    • Mihnea Costin Manea
    • Magdalena Budisteanu
    • Emanuela Andrei
    • Florentina Linca
    • Florina Rad
    • Romica Cergan
    • Adela Magdalena Ciobanu
  • View Affiliations

  • Published online on: August 2, 2021     https://doi.org/10.3892/etm.2021.10532
  • Article Number: 1098
  • Copyright: © Iliuta et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Schizophrenia is a severe mental illness with a significant impact on the life of both the patient and the patient's family. Magnetic resonance imaging has proven a useful tool for studying structural changes of the brain in schizophrenia. However, interpreting the published literature presents several challenges. Despite thorough research in recent years, which has included anatomopathological, imaging, electrophysiological, and genetic studies, the intimate pathophysiological mechanisms of this disease are not yet fully elucidated. The present study included patients with schizophrenia diagnosed in the psychiatric clinics from the ‘Prof. Dr. Alexandru Obregia’ Clinical Psychiatry Hospital between September 2019 and December 2020. Three Tesla magnetic resonance neuroimaging studies were performed. In a significant number of cases, the neuroimaging studies showed association of cerebral modifications such as enlargement of the Virchow spaces, lesions of the white matter with demyelinating appearance, and inflammatory sinus reactions. Cortical atrophy and hemosiderotic spots were present in a statistically significant proportion in the patient group with an age range of 29‑61 years. MRI is indicated as a useful technique in the follow‑up process of schizophrenia patients. However, whether the anomalies revealed in this disorder can be utilised as diagnostic biomarkers is still being debated.
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October-2021
Volume 22 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Iliuta FP, Manea MC, Budisteanu M, Andrei E, Linca F, Rad F, Cergan R and Ciobanu AM: Magnetic resonance imaging of brain anomalies in adult and pediatric schizophrenia patients: Experience of a Romanian tertiary hospital. Exp Ther Med 22: 1098, 2021
APA
Iliuta, F.P., Manea, M.C., Budisteanu, M., Andrei, E., Linca, F., Rad, F. ... Ciobanu, A.M. (2021). Magnetic resonance imaging of brain anomalies in adult and pediatric schizophrenia patients: Experience of a Romanian tertiary hospital. Experimental and Therapeutic Medicine, 22, 1098. https://doi.org/10.3892/etm.2021.10532
MLA
Iliuta, F. P., Manea, M. C., Budisteanu, M., Andrei, E., Linca, F., Rad, F., Cergan, R., Ciobanu, A. M."Magnetic resonance imaging of brain anomalies in adult and pediatric schizophrenia patients: Experience of a Romanian tertiary hospital". Experimental and Therapeutic Medicine 22.4 (2021): 1098.
Chicago
Iliuta, F. P., Manea, M. C., Budisteanu, M., Andrei, E., Linca, F., Rad, F., Cergan, R., Ciobanu, A. M."Magnetic resonance imaging of brain anomalies in adult and pediatric schizophrenia patients: Experience of a Romanian tertiary hospital". Experimental and Therapeutic Medicine 22, no. 4 (2021): 1098. https://doi.org/10.3892/etm.2021.10532