1
|
Tham YC, Li X, Wong TY, Quigley HA, Aung T
and Cheng CY: Global prevalence of glaucoma and projections of
glaucoma burden through 2040: A systematic review and
meta-analysis. Ophthalmology. 121:2081–2090. 2014.PubMed/NCBI View Article : Google Scholar
|
2
|
Bourne RR, Taylor HR, Flaxman SR, Keeffe
J, Leasher J, Naidoo K, Pesudovs K, White RA, Wong TY, Resnikoff S,
et al: Number of people blind or visually impaired by glaucoma
worldwide and in world regions 1990-2010: A meta-analysis. PLoS
One. 11(e0162229)2016.PubMed/NCBI View Article : Google Scholar
|
3
|
Rhee DJ, Fariss RN, Brekken R, Sage EH and
Russell P: The matricellular protein SPARC is expressed in human
trabecular meshwork. Exp Eye Res. 77:601–607. 2003.PubMed/NCBI View Article : Google Scholar
|
4
|
Vittal V, Rose A, Gregory KE, Kelley MJ
and Acott TS: Changes in gene expression by trabecular meshwork
cells in response to mechanical stretching. Invest Ophthalmol Vis
Sci. 46:2857–2868. 2005.PubMed/NCBI View Article : Google Scholar
|
5
|
Haddadin RI, Oh DJ, Kang MH, Filippopoulos
T, Gupta M, Hart L and Rhee DJ: SPARC-null mice exhibit lower
intraocular pressures. Invest Ophthalmol Vis Sci. 50:3771–3777.
2009.PubMed/NCBI View Article : Google Scholar
|
6
|
Chua J, Seet LF, Jiang Y, Su R, Htoon HM,
Charlton A, Aung T and Wong TT: Increased SPARC expression in
primary angle closure glaucoma iris. Mol Vis. 14:1886–1892.
2008.PubMed/NCBI
|
7
|
Stamer WD: The cell and molecular biology
of glaucoma: Mechanisms in the conventional outflow pathway. Invest
Ophthalmol Vis Sci. 53:2470–2472. 2012.PubMed/NCBI View Article : Google Scholar
|
8
|
Tian B, Gabelt BT, Geiger B and Kaufman
PL: The role of the actomyosin system in regulating trabecular
fluid outflow. Exp Eye Res. 88:713–717. 2009.PubMed/NCBI View Article : Google Scholar
|
9
|
Bradshaw AD: The role of secreted protein
acidic and rich in cysteine (SPARC) in cardiac repair and fibrosis:
Does expression of SPARC by macrophages influence outcomes? J Mol
Cell Cardiol. 93:156–161. 2016.PubMed/NCBI View Article : Google Scholar
|
10
|
Nie J and Sage EH: SPARC functions as an
inhibitor of adipogenesis. J Cell Commun Signal. 3:247–254.
2009.PubMed/NCBI View Article : Google Scholar
|
11
|
Stamer WD and Clark AF: The many faces of
the trabecular meshwork cell. Exp Eye Res. 158:112–123.
2017.PubMed/NCBI View Article : Google Scholar
|
12
|
Fan BJ, Wang DY, Tham CC, Lam DS and Pang
CP: Gene expression profiles of human trabecular meshwork cells
induced by triamcinolone and dexamethasone. Invest Ophthalmol Vis
Sci. 49:1886–1897. 2008.PubMed/NCBI View Article : Google Scholar
|
13
|
Zufferey R, Nagy D, Mandel RJ, Naldini L
and Trono D: Multiply attenuated lentiviral vector achieves
efficient gene delivery in vivo. Nat Biotechnol. 15:871–875.
1997.PubMed/NCBI View Article : Google Scholar
|
14
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
15
|
Kutner RH, Zhang XY and Reiser J:
Production, concentration and titration of pseudotyped HIV-1-based
lentiviral vectors. Nat Protoc. 4:495–505. 2009.PubMed/NCBI View Article : Google Scholar
|
16
|
Shirato S, Murphy CG, Bloom E,
Franse-Carman L, Maglio MT, Polansky JR and Alvarado JA: Kinetics
of phagocytosis in trabecular meshwork cells. Flow cytometry and
morphometry. Invest Ophthalmol Vis Sci. 30:2499–2511.
1989.PubMed/NCBI
|
17
|
Johnson DH, Richardson TM and Epstein DL:
Trabecular meshwork recovery after phagocytic challenge. Curr Eye
Res. 8:1121–1130. 1989.PubMed/NCBI View Article : Google Scholar
|
18
|
Zhang X, Ognibene CM, Clark AF and Yorio
T: Dexamethasone inhibition of trabecular meshwork cell
phagocytosis and its modulation by glucocorticoid receptor beta.
Exp Eye Res. 84:275–284. 2007.PubMed/NCBI View Article : Google Scholar
|
19
|
Park CH and Latina MA: Effects of
gamma-interferon on human trabecular meshwork cell phagocytosis.
Invest Ophthalmol Vis Sci. 34:2228–2236. 1993.PubMed/NCBI
|
20
|
Yang X and Li M: Establishment of in vitro
culture of bovine trabecular meshwork cells and their phagocytosis.
Zhonghua Yan Ke Za Zhi. 32:136–139. 1996.PubMed/NCBI(In Chinese).
|
21
|
Last JA, Pan T, Ding Y, Reilly CM, Keller
K, Acott TS, Fautsch MP, Murphy CJ and Russell P: Elastic modulus
determination of normal and glaucomatous human trabecular meshwork.
Invest Ophthalmol Vis Sci. 52:2147–2152. 2011.PubMed/NCBI View Article : Google Scholar
|
22
|
Hoare MJ, Grierson I, Brotchie D, Pollock
N, Cracknell K and Clark AF: Cross-linked actin networks (CLANs) in
the trabecular meshwork of the normal and glaucomatous human eye in
situ. Invest Ophthalmol Vis Sci. 50:1255–1263. 2009.PubMed/NCBI View Article : Google Scholar
|
23
|
Lutjen-Drecoll E: Morphological changes in
glaucomatous eyes and the role of TGFbeta2 for the pathogenesis of
the disease. Exp Eye Res. 81:1–4. 2005.PubMed/NCBI View Article : Google Scholar
|
24
|
Morgan JT, Raghunathan VK, Chang YR,
Murphy CJ and Russell P: The intrinsic stiffness of human
trabecular meshwork cells increases with senescence. Oncotarget.
6:15362–15374. 2015.PubMed/NCBI View Article : Google Scholar
|
25
|
Chen QM, Tu VC, Catania J, Burton M,
Toussaint O and Dilley T: Involvement of Rb family proteins, focal
adhesion proteins and protein synthesis in senescent morphogenesis
induced by hydrogen peroxide. J Cell Sci. 113:4087–4097.
2000.PubMed/NCBI
|
26
|
Tian B, Geiger B, Epstein DL and Kaufman
PL: Cytoskeletal involvement in the regulation of aqueous humor
outflow. Invest Ophthalmol Vis Sci. 41:619–623. 2000.PubMed/NCBI
|
27
|
Clark AF, Brotchie D, Read AT, Hellberg P,
English-Wright S, Pang IH, Ethier CR and Grierson I: Dexamethasone
alters F-actin architecture and promotes cross-linked actin network
formation in human trabecular meshwork tissue. Cell Motil
Cytoskeleton. 60:83–95. 2005.PubMed/NCBI View
Article : Google Scholar
|
28
|
Stumpff F and Wiederholt M: Regulation of
trabecular meshwork contractility. Ophthalmologica. 214:33–53.
2000.PubMed/NCBI View Article : Google Scholar
|
29
|
Kaufman PL: Enhancing trabecular outflow
by disrupting the actin cytoskeleton, increasing uveoscleral
outflow with prostaglandins, and understanding the pathophysiology
of presbyopia interrogating Mother Nature: Asking why, asking how,
recognizing the signs, following the trail. Exp Eye Res. 86:3–17.
2008.PubMed/NCBI View Article : Google Scholar
|
30
|
Sanka K, Maddala R, Epstein DL and Rao PV:
Influence of actin cytoskeletal integrity on matrix
metalloproteinase-2 activation in cultured human trabecular
meshwork cells. Invest Ophthalmol Vis Sci. 48:2105–2114.
2007.PubMed/NCBI View Article : Google Scholar
|
31
|
Gilles C, Bassuk JA, Pulyaeva H, Sage EH,
Foidart JM and Thompson EW: SPARC/osteonectin induces matrix
metalloproteinase 2 activation in human breast cancer cell lines.
Cancer Res. 58:5529–5536. 1998.PubMed/NCBI
|
32
|
Liu X, Wu Z, Sheibani N, Brandt CR,
Polansky JR and Kaufman PL: Low dose latrunculin-A inhibits
dexamethasone-induced changes in the actin cytoskeleton and alters
extracellular matrix protein expression in cultured human
trabecular meshwork cells. Exp Eye Res. 77:181–188. 2003.PubMed/NCBI View Article : Google Scholar
|
33
|
Yamada KM and Geiger B: Molecular
interactions in cell adhesion complexes. Curr Opin Cell Biol.
9:76–85. 1997.PubMed/NCBI View Article : Google Scholar
|
34
|
Shen L: Tight junctions on the move:
Molecular mechanisms for epithelial barrier regulation. Ann N Y
Acad Sci. 1258:9–18. 2012.PubMed/NCBI View Article : Google Scholar
|
35
|
Katsuno T, Umeda K, Matsui T, Hata M,
Tamura A, Itoh M, Takeuchi K, Fujimori T, Nabeshima Y, Noda T, et
al: Deficiency of zonula occludens-1causes embryonic lethal
phenotype associated with defected yolk sac angiogenesis and
apoptosis of embryonic cells. Mol Biol Cell. 19:2465–2475.
2008.PubMed/NCBI View Article : Google Scholar
|
36
|
Yang JG, Zhou CJ, Li XY, Sun PR, Li SP and
Ren BC: Alteration of UCP2 and ZO-1 expression in trabecular
meshwork of neovascular glaucoma patients. J Glaucoma. 24:291–296.
2015.PubMed/NCBI View Article : Google Scholar
|
37
|
Yang X, Liu B, Bai Y, Chen M, Li Y, Chen
M, Wei Y, Ge J and Zhuo Y: Elevated pressure downregulates ZO-1
expression and disrupts cytoskeleton and focal adhesion in human
trabecular meshwork cells. Mol Vis. 17:2978–2985. 2011.PubMed/NCBI
|
38
|
Zhuo YH, He Y, Leung KW, Hou F, Li YQ,
Chai F and Ge J: . Dexamethasone disrupts intercellular junction
formation and cytoskeleton organization in human trabecular
meshwork cells. Mol Vis. 16:61–71. 2010.PubMed/NCBI
|
39
|
Yan Q, Clark JI and Sage EH: Expression
and characterization of SPARC in human lens and in the aqueous and
vitreous humors. Exp Eye Res. 71:81–90. 2000.PubMed/NCBI View Article : Google Scholar
|
40
|
Gilbert RE, Cox AJ, Kelly DJ,
Wilkinson-Berka JL, Sage EH, Jerums G and Cooper ME: Localization
of secreted protein acidic and rich in cysteine (SPARC) expression
in the rat eye. Connect. Tissue Res. 40:295–303. 1999.PubMed/NCBI View Article : Google Scholar
|
41
|
Rodriguez IR, Moreira EF, Bok D and
Kantorow M: Osteonectin/SPARC secreted by RPE and localized to the
outer plexiform layer of the monkey retina. Invest Ophthalmol Vis
Sci. 41:2438–2444. 2000.PubMed/NCBI
|
42
|
Tomarev SI, Wistow G, Raymond V, Dubois S
and Malyukova I: Gene expression profile of the human trabecular
meshwork: NEIBank sequence tag analysis. Invest Ophthalmol Vis Sci.
44:2588–2596. 2003.PubMed/NCBI View Article : Google Scholar
|
43
|
Comes N and Borras T: Individual molecular
response to elevated intraocular pressure in perfused postmortem
human eyes. Physiol Genomics. 38:205–225. 2009.PubMed/NCBI View Article : Google Scholar
|
44
|
Swaminathan SS, Oh DJ, Kang MH, Shepard
AR, Pang I and Rhee DJ: TGFβ2-mediated ocular hypertension is
attenuated in SPARC-null mice. Invest Ophthalmol Vis Sci.
55:4084–4097. 2014.PubMed/NCBI View Article : Google Scholar
|