Open Access

Evaluation of the SF‑36 questionnaire for assessment of the quality of life of endometriosis patients undergoing treatment: A systematic review and meta‑analysis

  • Authors:
    • Romina-Marina Sima
    • Liana Pleş
    • Bogdan Socea
    • Panagiotis Sklavounos
    • Ionuţ Negoi
    • Anca-Daniela Stănescu
    • Ioan-Iulian Iordache
    • Bashar Haj Hamoud
    • Marc Phillip Radosa
    • Ingolf Juhasz‑Boess
    • Erich Franz Solomayer
    • Mihai C.T. Dimitriu
    • Cătălin Cîrstoveanu
    • Dragoş Şerban
    • Julia Caroline Radosa
  • View Affiliations

  • Published online on: September 13, 2021     https://doi.org/10.3892/etm.2021.10718
  • Article Number: 1283
  • Copyright: © Sima et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Endometriosis has a negative influence on the physical, psychological, and social aspects of a patient's life; therefore, it affects the health‑related quality of life (HRQoL). The current review aimed to investigate the efficiency of a 36‑item generic questionnaire survey (SF‑36) for patients with endometriosis who were undergoing medical or surgical treatment. A search strategy including the key words ‘endometriosis’, ‘quality of life’ (QOL), and ‘questionnaire SF‑36’ was applied using the PubMed/MEDLINE, EMBASE, and Cochrane databases in order to include articles that evaluated the QOL among women with endometriosis using the SF‑36. Only articles that included interviews of patients both before and after surgical or medical endometriosis treatment or those articles that compared study groups were considered. The qualitative analysis was based on 37 articles, whereas the quantitative analysis utilized 14 articles. The research participants included 11,101 women, among whom 6,888 patients were diagnosed with endometriosis. The analysis recorded 17 studies dealing with all types of endometriosis, 9 studies dealing with deep infiltrative endometriosis (DIE), and 9 studies dealing with bowel endometriosis or DIE with bowel involvement. QOL was evaluated using only SF‑36 in 12 studies that collectively included 1,912 women and using SF‑36 in association with other questionnaires in 25 studies that collectively included 8,022 women. For patients with endometriosis, physical functioning [odds ratio (OR), 78.87; 95% confidence interval (CI), 68.97‑88.77; I2=98.77%; P≤0.001] was the most affected life parameter. This parameter showed the highest improvement after surgical intervention (OR, 63.39; 95% CI, 48.71‑78.07; I2=97.65%; P≤0.001) or hormonal treatment (OR, 38.65; 95% CI, 14.39‑62.91; I2=38.65%; P≤0.001). The 36‑item survey generic questionnaire seems to be an efficient tool for assessment of the QOL of life of women with endometriosis who are undergoing surgical or medical treatment. It can be applied before and after the procedure, and it can also be used for comparing study groups.
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November-2021
Volume 22 Issue 5

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Spandidos Publications style
Sima R, Pleş L, Socea B, Sklavounos P, Negoi I, Stănescu A, Iordache I, Hamoud BH, Radosa MP, Juhasz‑Boess I, Juhasz‑Boess I, et al: Evaluation of the SF‑36 questionnaire for assessment of the quality of life of endometriosis patients undergoing treatment: A systematic review and meta‑analysis. Exp Ther Med 22: 1283, 2021
APA
Sima, R., Pleş, L., Socea, B., Sklavounos, P., Negoi, I., Stănescu, A. ... Radosa, J.C. (2021). Evaluation of the SF‑36 questionnaire for assessment of the quality of life of endometriosis patients undergoing treatment: A systematic review and meta‑analysis. Experimental and Therapeutic Medicine, 22, 1283. https://doi.org/10.3892/etm.2021.10718
MLA
Sima, R., Pleş, L., Socea, B., Sklavounos, P., Negoi, I., Stănescu, A., Iordache, I., Hamoud, B. H., Radosa, M. P., Juhasz‑Boess, I., Solomayer, E. F., Dimitriu, M. C., Cîrstoveanu, C., Şerban, D., Radosa, J. C."Evaluation of the SF‑36 questionnaire for assessment of the quality of life of endometriosis patients undergoing treatment: A systematic review and meta‑analysis". Experimental and Therapeutic Medicine 22.5 (2021): 1283.
Chicago
Sima, R., Pleş, L., Socea, B., Sklavounos, P., Negoi, I., Stănescu, A., Iordache, I., Hamoud, B. H., Radosa, M. P., Juhasz‑Boess, I., Solomayer, E. F., Dimitriu, M. C., Cîrstoveanu, C., Şerban, D., Radosa, J. C."Evaluation of the SF‑36 questionnaire for assessment of the quality of life of endometriosis patients undergoing treatment: A systematic review and meta‑analysis". Experimental and Therapeutic Medicine 22, no. 5 (2021): 1283. https://doi.org/10.3892/etm.2021.10718