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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2021 Volume 22 Issue 5

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Impact Factor: 2.3

Article Open Access

Value of GastroPanel in the diagnosis of atrophic gastritis

Cosmin Grad, Andrei Pop, Emil Gaborean, Simona Grad, Dan Dumitrascu
Article Number: 1347
Published online on: 22 September 2021

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Review Open Access

A systematic review of euthyroid Graves' disease (Review)

Mioara-Laura Macovei, Űnal Azis, Alina Gabriela Gheorghe, Marian Burcea
Article Number: 1346
Published online on: 22 September 2021

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Review

Pheochromocytoma as a rare hypertensive complication rarely associated with pregnancy: Diagnostic difficulties (Review)

Irina Pacu, Nikolaos Zygouropoulos, Cristian George Furau, Dan Navolan, Delia Mirela Tit, Cringu A. Ionescu, Anca Pantea Stoian, Aida Petca, Mihai Dimitriu
Article Number: 1345
Published online on: 22 September 2021

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Review

Prediction of bleeding events using the VTE‑BLEED risk score in patients with venous thromboembolism receiving anticoagulant therapy (Review)

Minerva Codruta Badescu, Manuela Ciocoiu, Oana Viola Badulescu, Maria-Cristina Vladeanu, Iris Bararu Bojan, Cristiana Elena Vlad, Ciprian Rezus
Article Number: 1344
Published online on: 22 September 2021

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Article Open Access

MEX3A knockdown inhibits the tumorigenesis of colorectal cancer via modulating CDK2 expression

Xin Zhou, Shaojie Li, Tiexiang Ma, Jian Zeng, Huanyu Li, Xiang Liu, Feng Li, Bin Jiang, Ming Zhao, Zhuo Liu, Yiyu Qin
Article Number: 1343
Published online on: 22 September 2021

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Article

Downregulation of MIAT reduces the proliferation and migratory and invasive abilities of retinoblastoma cells by sponging miR‑665 and regulating LASP1

Xiabing Xu, Yadong Zhao, Gang Duan, Bo Du
Article Number: 1342
Published online on: 22 September 2021

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Article

Blood glucose control contributes to protein stability of Ski‑related novel protein N in a rat model of diabetes

Luqun Liang, Shuang Li, Huiming Liu, Yanwen Mao, Lingling Liu, Xiaohuan Zhang, Wei Peng, Ying Xiao, Fan Zhang, Mingjun Shi, Yuanyuan Wang, Bing Guo
Article Number: 1341
Published online on: 22 September 2021

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Article Open Access

Long non‑coding RNA RP11‑84C13.1 promotes osteogenic differentiation of bone mesenchymal stem cells and alleviates osteoporosis progression via the miR‑23b‑3p/RUNX2 axis

Huaixi Yu, Yunyun Li, Jinshan Tang, Xiaoqing Lu, Wen Hu, Liang Cheng
Article Number: 1340
Published online on: 22 September 2021

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Article Open Access

Enhanced expression of KIF4A in osteosarcoma predicts a poor prognosis and facilitates tumor growth by activation of the MAPK pathway

Dongsheng Zhu, Xiangfei Xu, Ming Zhang, Tong Wang
Article Number: 1339
Published online on: 22 September 2021

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Review

Adrenal ganglioneuroma: Prognostic factors (Review)

Florica Sandru, Mihai Cristian Dumitrascu, Aida Petca, Mara Carsote, Razvan-Cosmin Petca, Ana Maria Oproiu, Adina Ghemigian
Article Number: 1338
Published online on: 22 September 2021

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Article Open Access

Progranulin: A proangiogenic factor in visceral adipose tissue in tumoral and non‑tumoral visceral pathology

Ioana Binișor, Ileana Monica Baniță, Dragoș Alexandru, Mihaela Cezarina Mehedinți, Sanda Jurja, Ana-Marina Andrei, Cătălina Gabriela Pisoschi
Article Number: 1337
Published online on: 22 September 2021

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Article Open Access

Predictive factors for the recurrence of surgically excised basal cell carcinomas: A retrospective clinical and immunopathological pilot study

Corina Vornicescu, Simona Corina Șenilă, Nona Ionela Bejinariu, Ștefan Cristian Vesa, Adina Bianca Boșca, Daciana Narcisa Chirilă, Carmen Stanca Melincovici, Olga Sorițău, Carmen Mihaela Mihu
Article Number: 1336
Published online on: 20 September 2021

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Review Open Access

Comprehensive review on the pathophysiology, clinical variants and management of pemphigus (Review)

Victor-Vlad Costan, Cristina Popa, Mădălina Florina Hâncu, Elena Porumb‑Andrese, Mihaela Paula Toader
Article Number: 1335
Published online on: 20 September 2021

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Review Open Access

Spongiotic reaction patterns in autoimmune bullous dermatoses (Review)

Raluca Anca Balan, Ludmila Lozneanu, Adriana Grigoras, Irina Draga Caruntu, Teodora Ana Balan, Simona Eliza Giusca, Cornelia Amalinei
Article Number: 1334
Published online on: 20 September 2021

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Article

Anthropometric and metabolic profile of children with gene polymorphisms for primary lactose intolerance

Corina Pienar, Liviu Pop, Marilena Lăzărescu, Radmila Costăchescu, Edward Șeclăman
Article Number: 1333
Published online on: 20 September 2021

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Article Open Access

Effects of Psoralea corylifolia L. seed extract on AGEs‑induced cell proliferation and fibrotic factor expression in mesangial cells

Hyunah Chung, Eunhui Seo, Hee-Sook Jun
Article Number: 1332
Published online on: 20 September 2021

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Article

Keratosis pilaris atrophicans faciei: An observational, descriptive, retrospective clinical study

Gyula László Fekete, László Fekete, Nicoleta Neagu, Vladimir Bacârea, Miruna Drăgănescu, Ilarie Brihan
Article Number: 1331
Published online on: 20 September 2021

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Review

Skin anomalies in acromegalic patients (Review of the practical aspects)

Florica Sandru, Adelina Popa, Dan Nicolae Paduraru, Alexandru Filipescu, Mara Carsote, Adina Ghemigian
Article Number: 1330
Published online on: 20 September 2021

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Review

Modern markers for evaluating bone disease in multiple myeloma (Review)

Vlad Pop, Andrada Parvu, Alexandra Craciun, Anca Daniela Farcas, Gheorghe Tomoaia, Anca Bojan
Article Number: 1329
Published online on: 20 September 2021

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Article Open Access

miR‑515‑5p inhibits the proliferation, migration and invasion of human breast cancer cells by targeting CBX4

Liu-Jing Wen, Yue-Sheng Wang, Pei-Yi Tan
Article Number: 1328
Published online on: 20 September 2021

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Review

Research progress on evodiamine, a bioactive alkaloid of Evodiae fructus: Focus on its anti‑cancer activity and bioavailability (Review)

Chaodan Luo, Jingwen Ai, Erfang Ren, Jianqiang Li, Chunmei Feng, Xinrong Li, Xiaojie Luo
Article Number: 1327
Published online on: 20 September 2021

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Article Open Access

Cycloastragenol and Astragaloside IV activate telomerase and protect nucleus pulposus cells against high glucose‑induced senescence and apoptosis

Haofeng Hong, Jian Xiao, Quanquan Guo, Jinhui Du, Zhichen Jiang, Sisi Lu, Hongyuan Zhang, Xiaolei Zhang, Xiangyang Wang
Article Number: 1326
Published online on: 20 September 2021

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Article

Efficacy and safety of tenofovir alafenamide fumarate in nucleoside analogue treatment-naïve patients with chronic hepatitis B

Peng Chen, Wei Wei, Li Jin, Wentao Kuai, Fei Li, Huan Liu, Bei Jiang, Yu Zhu
Article Number: 1325
Published online on: 20 September 2021

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Article Open Access

Effects of ulinastatin on renal perfusion evaluated by Doppler ultrasonography in a porcine model of septic shock

Chen-Chen Hang, Yu-Hong Guo, Chun-Sheng Li, Shuo Wang
Article Number: 1324
Published online on: 20 September 2021

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Article Open Access

miR‑489‑3p overexpression inhibits lipopolysaccharide‑induced nucleus pulposus cell apoptosis, inflammation and extracellular matrix degradation via targeting Toll‑like receptor 4

Ling Dong, Bo Dong
Article Number: 1323
Published online on: 20 September 2021

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Article

Intestinal flora alterations in patients with ulcerative colitis and their association with inflammation

Zhi Feng Dai, Xu Yuan Ma, Rui Lin Yang, Hui Chao Wang, Dan Dan Xu, Jing Nan Yang, Xiao Bing Guo, Shuang Shuang Meng, Rui Xu, Yu Xia Li, Yao Xu, Kun Li, Xu Hong Lin
Article Number: 1322
Published online on: 20 September 2021

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Article

Gas6/Axl signaling pathway promotes proliferation, migration and invasion and inhibits apoptosis in A549 cells

Dong Wang, Lixin Bi, Jingping Ran, Lei Zhang, Na Xiao, Xiaoli Li
Article Number: 1321
Published online on: 20 September 2021

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Article Open Access

An enriched environment delays the progression from mild cognitive impairment to Alzheimer's disease in senescence‑accelerated mouse prone 8 mice

Jian-Zhong Li, Xing-Hua Hao, Hai-Ping Wu, Ming Li, Xue-Min Liu, Zhi-Bing Wu
Article Number: 1320
Published online on: 20 September 2021

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Article Open Access

miR‑638 suppresses proliferation by negatively regulating high mobility group A1 in ovarian cancer cells

Li Ma, Wei Zhang, Yaofeng Jin, Xiaomei Bai, Qiaoling Yu
Article Number: 1319
Published online on: 20 September 2021

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Article Open Access

MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 1318
Published online on: 20 September 2021

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Article Open Access

Gigantol inhibits cell proliferation and induces apoptosis by regulating DEK in non‑small cell lung cancer

Yuxing Cai, Yi Hao, Hui Xu, Kai Chen, Baozhong Ren
Article Number: 1317
Published online on: 17 September 2021

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Article Open Access

Metformin attenuates H2O2‑induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway

Keda Yang, Lei Pei, Siming Zhou, Lin Tao, Yue Zhu
Article Number: 1316
Published online on: 17 September 2021

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Review Open Access

Biocompatibility assessment of biomaterials used in orthopedic devices: An overview (Review)

Bogdan Huzum, Bogdan Puha, Riana Maria Necoara, Stefan Gheorghevici, Gabriela Puha, Alexandru Filip, Paul Dan Sirbu, Ovidiu Alexa
Article Number: 1315
Published online on: 17 September 2021

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Review

Neoadjuvant intraperitoneal chemotherapy for advanced stage gastric cancer (Review)

Nicolae Bacalbasa, Camelia Diaconu, Bogdan Socea, Florentina Gherghiceanu, Cornel Savu, Mihai Dimitriu, Irina Balescu, Ioan Cordos
Article Number: 1314
Published online on: 17 September 2021

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Review

Dermatological and endocrine elements in Carney complex (Review)

Florica Sandru, Mihai Cristian Dumitrascu, Aida Petca, Mara Carsote, Razvan-Cosmin Petca, Diana Loreta Paun
Article Number: 1313
Published online on: 17 September 2021

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Article Open Access

Dietary Bacillus subtilis supplementation alleviates alcohol‑induced liver injury by maintaining intestinal integrity and gut microbiota homeostasis in mice

Meiqi Zhao, Chuanai Chen, Zhoujie Yuan, Wenwen Li, Mohan Zhang, Nailing Cui, Yitao Duan, Xiaoqian Zhang, Peng Zhang
Article Number: 1312
Published online on: 16 September 2021

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Article Open Access

Blocking tumor necrosis factor-α delays progression of chronic obstructive pulmonary disease in rats through inhibiting MAPK signaling pathway and activating SOCS3/TRAF1

Qiong Feng, Yan-Zi Yu, Qing-Hua Meng
Article Number: 1311
Published online on: 16 September 2021

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Article Open Access

HOXC11 positively regulates the long non-coding RNA HOTAIR and is associated with poor prognosis in colon adenocarcinoma

Nana Gong, Fei Li, Yanan Wang, Zizi Li, Wanqiu Wang, Tingting Gong, Xiaojun Meng, Hongtao Chen
Article Number: 1310
Published online on: 16 September 2021

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Article Open Access

Matrine ameliorates the inflammatory response and lipid metabolism in vascular smooth muscle cells through the NF‑κB pathway

Guanglei Wang, Chengyu Ji, Chunling Wang, Zhonghui Liu, Aizhong Qu, Huaixin Wang
Article Number: 1309
Published online on: 16 September 2021

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Article Open Access

Yiqi Huoxue preserves heart function by upregulating the Sigma‑1 receptor in rats with myocardial infarction

Lixia Lou, Chunhong Li, Jie Wang, Aiming Wu, Ting Zhang, Zhe Ma, Limin Chai, Dongmei Zhang, Yizhou Zhao, Bo Nie, Qiushuo Jin, Huiyang Chen, Wei Jing Liu
Article Number: 1308
Published online on: 16 September 2021

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Article Open Access

Ononin alleviates H2O2‑induced cardiomyocyte apoptosis and improves cardiac function by activating the AMPK/mTOR/autophagy pathway

Rongrong Pan, Qin Zhuang, Jiangtin Wang
Article Number: 1307
Published online on: 16 September 2021

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Article Open Access

Maiwei Yangfei decoction prevents bleomycin‑induced pulmonary fibrosis in mice

Yong Xu, Wenpan Peng, Di Han, Fanchao Feng, Zhichao Wang, Cheng Gu, Xianmei Zhou, Qi Wu
Article Number: 1306
Published online on: 16 September 2021

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Article Open Access

Anticancer roles of let‑7f‑1‑3p in non‑small cell lung cancer via direct targeting of integrin β1

Yanan Yang, Yuanrong Liu, Ning Xie, Liying Shao, Hang Sun, Yubo Wei, Yunxiao Sun, Pingyu Wang, Yunfei Yan, Shuyang Xie, Youjie Li
Article Number: 1305
Published online on: 16 September 2021

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Article Open Access

Exosomes derived from PC‑3 cells suppress osteoclast differentiation by downregulating miR‑148a and blocking the PI3K/AKT/mTOR pathway

Gaoqiang Tian, Konghe Hu, Sujun Qiu, Yingming Xie, Yanlin Cao, Songjia Ni, Lifang Zhang
Article Number: 1304
Published online on: 16 September 2021

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Article Open Access

Insulin receptor substrate‑1 and dishevelled 2 are negatively regulated by microRNA‑144 and inhibit nasopharyngeal carcinoma cell malignancy

Xuemei An, Yunlan Jiang, Defeng Chen, Jianjun Chen
Article Number: 1303
Published online on: 16 September 2021

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Article Open Access

Panax notoginseng saponins alleviate osteoporosis and joint destruction in rabbits with antigen‑induced arthritis

Chen Chao Wei, Li Fei Yue, Fan Tian You, Che Tao
Article Number: 1302
Published online on: 16 September 2021

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Article

Honokiol combined with curcumin sensitizes multidrug‑resistant human lung adenocarcinoma A549/DDP cells to cisplatin

Mingming Qi, Xiaojin Chen, Liqun Bian, Han Zhang, Jian Ma
Article Number: 1301
Published online on: 16 September 2021

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Article

Effects of isoflavone derivatives on the production of inflammatory cytokines by synovial cells

Nuerbiyemu Mijiti, Akimasa Someya, Isao Nagaoka
Article Number: 1300
Published online on: 16 September 2021

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Article Open Access

TFAP4 promotes the growth of prostate cancer cells by upregulating FOXK1 Retraction in /10.3892/etm.2024.12754

Yuan Gu, Jiujin Jiang, Chaozhao Liang
Article Number: 1299
Published online on: 16 September 2021

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Article Open Access

Patients affected by squamous cell carcinoma of the head and neck: A population particularly prone to developing severe forms of COVID‑19

Francesco Perri, Anna Crispo, Franco Ionna, Paolo Muto, Francesco Caponigro, Francesco Longo, Concetta Montagnese, Pierluigi Franco, Ettore Pavone, Corrado Aversa, Agostino Guida, Sabrina Bimonte, Alessandro Ottaiano, Massimiliano Di Marzo, Giuseppe Porciello, Alfonso Amore, Egidio Celentano, Giuseppina Della Vittoria Scarpati, Marco Cascella
Article Number: 1298
Published online on: 16 September 2021

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Review

Renal tumor biomarkers (Review)

Ovidiu Bratu, Dan Mischianu, Dragos Marcu, Dan Spinu, Lucian Iorga, Alexandru Cherciu, Irina Balescu, Nicolae Bacalbasa, Camelia Diaconu, Cornel Savu, Carmen Savu, Radu Anghel
Article Number: 1297
Published online on: 14 September 2021

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Review Open Access

Extracorporeal membrane oxygenation in the management of critically ill patients with coronavirus disease 2019: A narrative review

Alexandru Florin Pleșoianu, Carmen Elena Pleșoianu, Iris Bararu‑Bojan (Bararu), Maria-Cristina Vlădeanu (Apăvăloaei), Andrei Bojan, Andrei Țăruș, Grigore Tinică
Article Number: 1296
Published online on: 14 September 2021

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Article Open Access

Ubisol Coenzyme Q10 promotes mitochondrial biogenesis in HT22 cells challenged by glutamate

Mary A. Zimmerman, Mia Hall, Qi Qi, Suresh L. Mehta, Guisheng Chen, P. Andy Li
Article Number: 1295
Published online on: 14 September 2021

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Retraction Open Access

[Retracted] MicroRNA‑33b inhibits cell proliferation and glycolysis by targeting hypoxia‑inducible factor‑1α in malignant melanoma

Yue Zhao, Cuiling Wu, Lina Li
Article Number: 1294
Published online on: 13 September 2021

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Retraction Open Access

[Retracted] MicroRNA‑30a‑5p inhibits the proliferation and invasion of gastric cancer cells by targeting insulin‑like growth factor 1 receptor

Yang Liu, Yu Zhou, Xun Gong, Changjie Zhang
Article Number: 1293
Published online on: 13 September 2021

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Review Open Access

Brain‑derived neurotrophic factor in autoimmune inflammatory diseases (Review)

Ningning Wang, Bailing Tian
Article Number: 1292
Published online on: 13 September 2021

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Article Open Access

Interleukin‑17 activates JAK2/STAT3, PI3K/Akt and nuclear factor‑κB signaling pathway to promote the tumorigenesis of cervical cancer

Yanfei Bai, Haitao Li, Rui Lv
Article Number: 1291
Published online on: 13 September 2021

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Article Open Access

LIPOSA pharmacopuncture, a new herbal formula, affects localized adiposity by regulating lipid metabolism in vivo

Haesu Lee, Mi Hye Kim, Seong Chul Jin, La Yoon Choi, Yeon Kyung Nam, Woong Mo Yang
Article Number: 1290
Published online on: 13 September 2021

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Article Open Access

Role of caveolin‑1 in chronic postsurgical pain in rats

Sai-Sai Huang, Su Cao, Yi-Bin Qin, Cui E. Lu, Shi-Ren Shen
Article Number: 1289
Published online on: 13 September 2021

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Article Open Access

MicroRNA‑24 protects against myocardial ischemia‑reperfusion injury via the NF‑κB/TNF‑α pathway

Chenlei Li, Ming Fang, Zhikang Lin, Wenhui Wang, Xinming Li
Article Number: 1288
Published online on: 13 September 2021

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Article Open Access

Sinomenine hydrochloride ameliorates dextran sulfate sodium‑induced colitis in mice by modulating the gut microbiota composition whilst suppressing the activation of the NLRP3 inflammasome

Yan Zhou, Shuai Chen, Wenxian Gu, Xiao Sun, Linxiao Wang, Liming Tang
Article Number: 1287
Published online on: 13 September 2021

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Article Open Access

Knockdown of lncRNA TUG1 protects lens epithelial cells from oxidative stress‑induced injury by regulating miR‑196a‑5p expression in age‑related cataracts

Qimin Shen, Tian Zhou
Article Number: 1286
Published online on: 13 September 2021

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Case Report Open Access

Leiomyoma of the uterine round ligament: A case report

Aliki Tympa, Charalampos Grigoriadis, Emmanouil Terzakis, Christina Goudeli, Aikaterini Melemeni
Article Number: 1285
Published online on: 13 September 2021

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Article

Prognostic value of miR‑1181 in non‑small cell lung cancer and its regulatory effect on tumor progression

Feng Liu, Guodong Ma, Bo Wang, Xiang Wang, Chenjun Huang
Article Number: 1284
Published online on: 13 September 2021

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Evaluation of the SF‑36 questionnaire for assessment of the quality of life of endometriosis patients undergoing treatment: A systematic review and meta‑analysis

Romina-Marina Sima, Liana Pleş, Bogdan Socea, Panagiotis Sklavounos, Ionuţ Negoi, Anca-Daniela Stănescu, Ioan-Iulian Iordache, Bashar Haj Hamoud, Marc Phillip Radosa, Ingolf Juhasz‑Boess, Erich Franz Solomayer, Mihai C.T. Dimitriu, Cătălin Cîrstoveanu, Dragoş Şerban, Julia Caroline Radosa
Article Number: 1283
Published online on: 13 September 2021

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Sequential growth factor exposure of human Ad‑MSCs improves chondrogenic differentiation in an osteochondral biphasic implant

Alejandro Garcia‑Ruiz, Celia N. Sánchez‑Domínguez, Nidia K. Moncada‑Saucedo, Vanessa Pérez‑Silos, Jorge Lara‑Arias, Iván A. Marino‑Martínez, Alberto Camacho‑Morales, Víktor J. Romero‑Diaz, Víctor Peña‑Martinez, Rosalío Ramos‑Payán, Yanko Castro‑Govea, Rocky S. Tuan, Hang Lin, Lizeth Fuentes‑Mera, Ana María Rivas‑Estilla
Article Number: 1282
Published online on: 13 September 2021

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Efficacy of electroconvulsive therapy as a potential first‑choice treatment in treatment‑resistant depression (Review)

Simona Trifu, Anca Sevcenco, Monica Stănescu, Ana Miruna Drăgoi, Mihai Bogdan Cristea
Article Number: 1281
Published online on: 09 September 2021

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Retraction Open Access

[Retracted] Paraptosis triggers mitochondrial pathway‑mediated apoptosis in Alzheimer’s disease

Dong-Pei Jia, Song Wang, Bao-Chao Zhang, Fang Fang
Article Number: 1280
Published online on: 09 September 2021

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Role of circular RNAs in osteoarthritis (Review)

Jicheng Wang, Bo Yang, Changkun Wu, Yongzhi Guo, Xin Jiang, Yangyang Zhang
Article Number: 1279
Published online on: 09 September 2021

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miR‑122‑5p downregulation attenuates lipopolysaccharide‑induced acute lung injury by targeting IL1RN

Jie Li, Xiaoxia Zeng, Weiqing Wang
Article Number: 1278
Published online on: 08 September 2021

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Case Report Open Access

Vasculitis associated with the use of an intrauterine device: A case report

Aurelian Mihai Ghita, Cristina Alexandrescu, Sanziana Istrate, Anca Evsei, Ana Cristina Ghita
Article Number: 1277
Published online on: 08 September 2021

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circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis Retraction in /10.3892/etm.2025.13033

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 1276
Published online on: 08 September 2021

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Novel function of fluvastatin in attenuating oxidized low‑density lipoprotein‑induced endothelial cell ferroptosis in a glutathione peroxidase4‑ and cystine‑glutamate antiporter‑dependent manner

Qing Li, Chang Liu, Liang Deng, Enrui Xie, Nishant Yadav, Yuanyuan Tie, Zheng Cheng, Jie Deng
Article Number: 1275
Published online on: 08 September 2021

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LINC00963 silencing inhibits the proliferation and migration of high glucose‑induced retinal endothelial cells via targeting miR‑27b

Rui Zhang, Chunhong Niu, Yuhan Guan, Jianhua Wu, Liping Hu
Article Number: 1274
Published online on: 08 September 2021

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Article

Silencing of long non‑coding RNA SNHG15 suppresses proliferation, migration and invasion of pancreatic cancer cells by regulating the microRNA‑345‑5p/RAB27B axis Retraction in /10.3892/etm.2025.12919

Pengfei Jiang, Youmin Yin, Yan Wu, Zhaoli Sun
Article Number: 1273
Published online on: 07 September 2021

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Article

Frequent injections of high‑dose human umbilical cord mesenchymal stem cells slightly aggravate arthritis and skeletal muscle cachexia in collagen‑induced arthritic mice

Lemei An, Tianshu Chu, Liujun Wang, Songtao An, Yalong Li, Hongbo Hao, Zhuoli Zhang, Han Yue
Article Number: 1272
Published online on: 07 September 2021

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TFEC contributes to cardiac hypertrophy by inhibiting AMPK/mTOR signaling

Ting Zhao, Zhenyu Wang, Yehong Chi, Chunmei Ni, Xudan Zheng
Article Number: 1271
Published online on: 07 September 2021

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Emerging roles of growth differentiation factor‑15 in brain disorders (Review)

Wei-Wei Jiang, Zi-Zhen Zhang, Ping-Ping He, Li-Ping Jiang, Jin-Zhi Chen, Xing-Ting Zhang, Mi Hu, Yang-Kai Zhang, Xin-Ping Ouyang
Article Number: 1270
Published online on: 07 September 2021

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Se alleviates homocysteine‑induced fibrosis in cardiac fibroblasts via downregulation of lncRNA MEG3

Wei Li, Yuanhong Li, Shengyu Cui, Jiayi Liu, Lijiao Tan, Hao Xia, Changjiang Zhang
Article Number: 1269
Published online on: 07 September 2021

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Association between obesity and iron deficiency (Review)

Naseem Mohammad Alshwaiyat, Aryati Ahmad, Wan Mohd Razin Wan Hassan, Hamid Ali Nagi Al‑Jamal
Article Number: 1268
Published online on: 07 September 2021

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Review

Determination of whether HIPEC is beneficial in patients with synchronous peritoneal and liver metastases from colorectal cancer (Review)

Nicolae Bacalbasa, Irina Balescu, Dragos Cretoiu, Ioana Halmaciu, Mihai Dimitriu, Bogdan Socea, Camelia Diaconu, Laura Iliescu, Cornel Savu, Carmen Savu, Alexandru Filipescu, Claudia Stoica, Ovidiu Stiru
Article Number: 1267
Published online on: 07 September 2021

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Review

HPV vaccine for men: Where to? (Review)

Arsenie Dan Spînu, Radu Florentin Anghel, Dragoș Radu Marcu, Daniel Lucian Iorga, Alexandru Cherciu, Dan Liviu Dorel Mischianu
Article Number: 1266
Published online on: 07 September 2021

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Insulin‑like growth factor 1 promotes neurological functional recovery after spinal cord injury through inhibition of autophagy via the PI3K/Akt/mTOR signaling pathway

Duo Zhang, Yuan Yuan, Jichao Zhu, Di Zhu, Chenxi Li, Wei Cui, Lei Wang, Song Ma, Shuo Duan, Baoge Liu
Article Number: 1265
Published online on: 06 September 2021

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Review Open Access

Current diagnosis and treatment of rhinosinusal aspergilloma (Review)

Daniela Vrinceanu, Mihai Dumitru, Oana Maria Patrascu, Adrian Costache, Toma Papacocea, Romica Cergan
Article Number: 1264
Published online on: 06 September 2021

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Biological therapies targeting the type 2 inflammatory pathway in severe asthma (Review)

Ariadna Petronela Fildan, Ruxandra-Mioara Rajnoveanu, Roxana Cirjaliu, Ionela Pohrib, Emanuela Tudorache, Adrian Cosmin Ilie, Cristian Oancea, Doina Tofolean
Article Number: 1263
Published online on: 06 September 2021

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Autophagy is involved in neurofibromatosis type I gene‑modulated osteogenic differentiation in human bone mesenchymal stem cells

Yiqiang Li, Mingwei Zhu, Xuemei Lin, Jingchun Li, Zhe Yuan, Yanhan Liu, Hongwen Xu
Article Number: 1262
Published online on: 06 September 2021

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Article

The added value of three‑dimensional ultrasonography in uterine pathology

Mihaela Grigore, Razvan Popovici, Loredana Maria Himiniuc, Ioana Sadiye Scripcariu, Bogdan Florin Toma, Ana Maria Grigore, Mihaela Oancea, Romeo Micu
Article Number: 1261
Published online on: 06 September 2021

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Quercetin suppresses inflammatory cytokine production in rheumatoid arthritis fibroblast‑like synoviocytes

Hai-Tao Sun, Jian-Peng Li, Wei-Qing Qian, Meng-Fan Yin, Hong Yin, Gui-Cheng Huang
Article Number: 1260
Published online on: 06 September 2021

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Gentianella acuta mitigates cardiovascular damage and inflammation in diet‑induced hypercholesterolaemic rats

Mingdong Si, Meng Wu, Yingying Huo, Aiying Li, Shengjiang Guan, Donglai Ma, Zhihong Ma
Article Number: 1259
Published online on: 06 September 2021

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes cell proliferation and invasion in osteosarcoma by directly targeting Dickkopf‑related protein 3

Qing Wu, Wei Zhou, Qiong Feng, Xing Liu, Yanfei Xiong, Hui Li
Article Number: 1258
Published online on: 03 September 2021

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Retraction Open Access

[Retracted] MicroRNA‑34a directly targets high‑mobility group box 1 and inhibits the cancer cell proliferation, migration and invasion in cutaneous squamous cell carcinoma

Shanshan Li, Chengqun Luo, Jun Zhou, Yong Zhang
Article Number: 1257
Published online on: 03 September 2021

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Construction of a new cervical anatomically adaptive titanium mesh cage based on measurements of cervical geometry: A morphological and cadaveric study

Teng Lu, Zhongyang Gao, Jialiang Li, Ning Liu, Yibin Wang, Chao Liu, Xijing He
Article Number: 1256
Published online on: 03 September 2021

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Consistency of pituitary adenomas: Amounts of collagen types I and III and the predictive value of T2WI MRI

Peiliang Li, Dainan Zhang, Shunchang Ma, Peng Kang, Chuanbao  Zhang, Beibei Mao, Wenjianlong Zhou, Xi Wang, Jiayi  Peng, Linhao  Yuan, Yangyang Wang, Jinfu Diao, Wang Jia
Article Number: 1255
Published online on: 03 September 2021

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Etomidate inhibits cell proliferation and induces apoptosis in A549 non‑small cell lung cancer cells via downregulating WWP2

Deqiang Li, Junlong Zhang, Lijun Yin, Zhen Jin, Xuejun Chen, Xiangxue Meng
Article Number: 1254
Published online on: 03 September 2021

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Antibodies against thyroid‑stimulating hormone receptor cause maternal‑neonatal transmission of Graves' Disease

Yue Yu, Qian-Qi Liu, De-Yun Liu, Dan-Dan Wang, Li-Qi Yang, Shu-Ming Ye
Article Number: 1253
Published online on: 03 September 2021

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Evidence‑based complementary and alternative medicine bioinformatics approach through network pharmacology and molecular docking to determine the molecular mechanisms of Erjing pill in Alzheimer's disease

Xiyang Yang, Yang Guan, Bo Yan, Yongyan Xie, Maofu Zhou, Yi Wu, Lihua Yao, Xiaopeng Qiu, Feixia Yan, Yaohui Chen, Liping Huang
Article Number: 1252
Published online on: 02 September 2021

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Role of miR‑139‑5p in ectopic endometrial stromal cells and the underlying molecular mechanism

Lixia Feng, Xu Chen, Shenghua Zhang, Yunxia Chen, Yanling Yu
Article Number: 1251
Published online on: 02 September 2021

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Prediction of in‑hospital recurrence and false‑negative results in patients with COVID‑19 by red blood cell values on admission

Xue Jiang, Yan Hu, Xiao-Peng Qu, Dong-Wei Xu, Hong Jiang, Chun-Mei Li, Hua Jiang, Da-Li Wang, Gang Li, Xin-Gen Zhu, Bei Liu
Article Number: 1250
Published online on: 02 September 2021

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Salidroside inhibits chronic myeloid leukemia cell proliferation and induces apoptosis by regulating the miR‑140‑5p/wnt5a/β‑catenin axis

Danjun Chen, Cong Luo
Article Number: 1249
Published online on: 02 September 2021

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Butorphanol alleviates lipopolysaccharide‑induced inflammation and apoptosis of cardiomyocytes via activation of the κ‑opioid receptor

Weiqing Tang, Liu Luo, Baoji Hu, Mingzhi Zheng
Article Number: 1248
Published online on: 02 September 2021

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LINC00473 exacerbates osteoarthritis development by promoting chondrocyte apoptosis and proinflammatory cytokine production through the miR‑424‑5p/LY6E axis

Guiyong Fan, Jinlian Liu, Yesong Zhang, Xinxian Guan
Article Number: 1247
Published online on: 02 September 2021

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Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide

Nan Wang, Peining Zhu, Renxuan Huang, Liankun Sun, Delu Dong, Yufei Gao
Article Number: 1246
Published online on: 02 September 2021

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Knockdown of DLGAP5 suppresses cell proliferation, induces G2/M phase arrest and apoptosis in ovarian cancer

Huijun Zhang, Yuan Liu, Shengchun Tang, Xiaomin  Qin, Lin  Li, Jinting Zhou, Jing Zhang, Bo Liu
Article Number: 1245
Published online on: 02 September 2021

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Article

Knockdown of LINC01385 inhibits osteoarthritis progression by modulating the microRNA‑140‑3p/TLR4 axis

Zidong Wang, Chuanwang Huang, Cunju Zhao, Huiling Zhang, Zhen Zhen, Duliang Xu
Article Number: 1244
Published online on: 02 September 2021

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Regulatory effect of insulin on the structure, function and metabolism of Na+/K+‑ATPase (Review)

Xu-Peng Wen, Qi-Quan Wan
Article Number: 1243
Published online on: 01 September 2021

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Article

Inhibitory effect of tumor necrosis factor‑α on the basolateral Kir4.1/Kir5.1 channels in the thick ascending limb during diabetes

Guoyan Zhang, Zhiming Lv, Yang Zhao, Rui Chen, Xiangyu Zhan, Weiqun Wang, Hongyu Sui
Article Number: 1242
Published online on: 01 September 2021

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Protective effect of 18β‑glycyrrhetinic acid against H2O2‑induced injury in Schwann cells based on network pharmacology and experimental validation

Di Zhang, Jianxin Sun, Shiquan Chang, Xing Li, Huimei Shi, Bei Jing, Yachun Zheng, Yi Lin, Guoqiang Qian, Yuwei Pan, Guoping Zhao
Article Number: 1241
Published online on: 01 September 2021

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Involvement of bradykinin and bradykinin B1 receptor in patients with endometriosis

Xin Meng, Ying Li, Qingxue Li, Jian Yang, Mingli An, Xinping Fu, Shuancheng Zhang, Jingwei Chen
Article Number: 1240
Published online on: 01 September 2021

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Article

Real‑life Cretan asthma registry focused on severe asthma: On behalf of ‘The Cretan registry of the use of Biologics in Severe Asthma’

Katerina M. Antoniou, Maria Bolaki, Konstantinos Karagiannis, Athina Trachalaki, Despo Ierodiakonou, Vagia Stamatopoulou, Charito Chatzinikolaou, Semeli Mastrodimou, Evangelia Stamataki, George Pitsidianakis, Irini Lambiri, Ioanna Mitrouska, Demetrios A. Spandidos, Nikolaos Tzanakis
Article Number: 1239
Published online on: 01 September 2021

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Rapid detection of human heart‑type fatty acid‑binding protein in human plasma and blood using a colloidal gold‑based lateral flow immunoassay

Yang-Guang Ren, Mei-Chen Liu, Meng-Zhen Ji, Chen Chen, Hang-Zhan Hu, Zi-Xuan Wang, Pin-Qian Yu, Jia-Ming Shang, Qian-Wen Zhou, Ning-Ya Tao, Ya-Fei Guo, Yan-Jiao Lu, Zhi-Zeng Wang
Article Number: 1238
Published online on: 31 August 2021

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Long non‑coding RNA miR155HG silencing restrains ovarian cancer progression by targeting the microRNA‑155‑5p/tyrosinase‑related protein 1 axis

Aiping Wen, Le Luo, Chengchao Du, Xin Luo
Article Number: 1237
Published online on: 31 August 2021

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Review Open Access

Role of protein phosphatase 2A in kidney disease (Review)

Lishi Shao, Yiqun Ma, Qixiang Fang, Ziye Huang, Shanshan Wan, Jiaping Wang, Li Yang
Article Number: 1236
Published online on: 31 August 2021

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Article

Neuroprotective role of epigallocatechin‑3‑gallate in acute glaucoma via the nuclear factor‑κB signalling pathway

Wen-Hua Zhang, Yu Chen, Li-Mo Gao, Yan-Na Cao
Article Number: 1235
Published online on: 31 August 2021

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Geniposide protects pulmonary arterial smooth muscle cells from lipopolysaccharide‑induced injury via α7nAchR‑mediated TLR‑4/MyD88 signaling

San-Ying Shen, Li-Quan Ren, Hui-Dong Chen, Hong-Fei Zhu, Deng-Feng Zhou, Bo Zhang, Xiao-Qin Tan, Yong-Hua Xie
Article Number: 1234
Published online on: 31 August 2021

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Article

TNFα regulates the expression of the CSE gene in HUVEC

Maoxian Wang
Article Number: 1233
Published online on: 31 August 2021

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Review

Benefits of α‑lipoic acid in high‑risk pregnancies (Review)

Aida Petca, Mihaela Bot, Nicoleta Maru, Ioana Gabriela Calo, Andreea Borislavschi, Mihai Cristian Dumitrascu, Razvan-Cosmin Petca, Florica Sandru, Mona Elena Zvanca
Article Number: 1232
Published online on: 31 August 2021

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Metformin attenuates angiotensin II‑induced cardiomyocyte hypertrophy by upregulating the MuRF1 and MAFbx pathway

Fawang Du, Yalin Cao, Yan Ran, Qiang Wu, Baolin Chen
Article Number: 1231
Published online on: 31 August 2021

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Moxibustion improves ovarian function based on the regulation of the androgen balance Corrigendum in /10.3892/etm.2022.11113

Xun Jin, Jie Cheng, Jie Shen, Xing Lv, Qian Li, Yanyun Mu, Hua Bai, Yan Liu, Youbing Xia
Article Number: 1230
Published online on: 30 August 2021

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Article

Long non‑coding RNA TUG1 accelerates abnormal growth of airway smooth muscle cells in asthma by targeting the miR‑138‑5p/E2F3 axis

Haiyin Zhou, Caixia Long, Pingping Liu, Yanying Chen, Lan Luo, Zhenghui Xiao
Article Number: 1229
Published online on: 27 August 2021

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LINC01094 promotes the invasion of ovarian cancer cells and regulates the Wnt/β‑catenin signaling pathway by targeting miR‑532‑3p Retraction in /10.3892/etm.2024.12545

Haiyan Chen, Yanlin Liu, Ping Liu, Qiuxiang Dai, Peiliang Wang
Article Number: 1228
Published online on: 27 August 2021

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Upregulating miR‑27a‑3p inhibits cell proliferation and inflammation of rheumatoid arthritis synovial fibroblasts through targeting toll‑like receptor 5

Lifeng Chen, Qiping Lu, Jianhua Chen, Ruibing Feng, Chenxi Yang
Article Number: 1227
Published online on: 27 August 2021

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IL‑1α, IL‑6 and IL‑8 serum values in patients with chronic suppurative otitis media

Roxana Serban, Cristiana Filip, Luminita Mihaela Radulescu, Minerva Codruta Badescu, Magda Mariana Badescu, Bogdan Mihail Diaconescu, Mihail Dan Cobzeanu, Bogdan Mihail Cobzeanu
Article Number: 1226
Published online on: 27 August 2021

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Antipsychotic polypharmacy in adult patients diagnosed with schizophrenia: A retrospective study

Bogdan Patrichi, Cristiana Ţăpoi, Radu Ştefan Rogojină, Irina Bedreagă, Anca Dumitrache, Andreea Itu, Radu Dragomir, Adela-Georgiana Buciuc
Article Number: 1225
Published online on: 27 August 2021

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COL4A1 as a novel oncogene associated with the clinical characteristics of malignancy predicts poor prognosis in glioma

Hongbo Wang, Zhendong Liu, Ang Li, Jialin Wang, Jiantao Liu, Binfeng Liu, Xiaoyu Lian, Bo Zhang, Bo Pang, Liyun Liu, Yanzheng Gao
Article Number: 1224
Published online on: 27 August 2021

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Anti‑inflammatory effects and enhancing immune response of freshwater hybrid catfish oil in RAW264.7 cells

Bussarin Tongmee, Atcharaporn Ontawong, Narissara Lailerd, Kriangsak Mengamphan, Doungporn Amornlerdpisan
Article Number: 1223
Published online on: 26 August 2021

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Resolvin D2 suppresses NLRP3 inflammasome by promoting autophagy in macrophages

Lijun Cao, Yiya Wang, Yina Wang, Feijuan Lv, Lixiu Liu, Zhen Li
Article Number: 1222
Published online on: 26 August 2021

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Review Open Access

Roles of circular RNAs in the pathogenesis of intervertebral disc degeneration (Review)

Zhidi Lin, Feizhou Lu, Xiaosheng Ma, Xinlei Xia, Fei Zou, Jianyuan Jiang
Article Number: 1221
Published online on: 26 August 2021

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Mangiferin inhibits hypoxia/reoxygenation‑induced alveolar epithelial cell injury via the SIRT1/AMPK signaling pathway

Xianfeng Chen, Juanjuan Huang
Article Number: 1220
Published online on: 26 August 2021

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Review

Neuroendocrine neoplasia and bone (Review)

Adina Ghemigian, Mara Carsote, Florica Sandru, Razvan-Cosmin Petca, Ana-Maria Oproiu, Aida Petca, Ana Valea
Article Number: 1219
Published online on: 26 August 2021

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Article

Accelerated lipid peroxidation in a rat model of gentamicin nephrotoxicity

Anamaria Magdalena Tomşa, Andreea Liana Răchişan, Stanca Lucia Pandrea, Andreea Benea, Ana Uifălean, Alina Elena Parvu, Lia Monica Junie
Article Number: 1218
Published online on: 26 August 2021

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Article

Ovarian cancer health politics in Romania and Germany: A comparative study

Ionut Marcel Cobec, Ioan Sas, Aurica Elisabeta Moatar, Lavinia Moleriu, Andreas Rempen
Article Number: 1217
Published online on: 26 August 2021

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Analysis of long‑term functional results of radical mastoidectomy

Horia Mocanu, Adela-Ioana Mocanu, Alexandru Bonciu, Gabriella Coadă, Mihai-Adrian Schipor, Marian Rădulescu
Article Number: 1216
Published online on: 26 August 2021

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Impact of COVID‑19 prevention measures on Clostridioides difficile infections in a regional acute care hospital

Simona Sipos, Cristian Vlad, Radu Prejbeanu, Horia Haragus, Daliborca Vlad, Horia Cristian, Cristian Dumitrascu, Roxana Popescu, Victor Dumitrascu, Vlad Predescu
Article Number: 1215
Published online on: 26 August 2021

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Correlation between metabolic status and diabetic retinopathy evolution in type 1 diabetes

Aurelia Romila, Vasile Potop, Radu Ciuluvica, Banita Monica, Mihaela Cezarina Mehedinti Hincu, Sanda Jurja
Article Number: 1214
Published online on: 26 August 2021

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Anti‑inflammation treatment for protection of hepatocytes and amelioration of hepatic fibrosis in rats

Shi Feng, Huan Tong, Jin-Hang Gao, Shi-Hang Tang, Wen-Juan Yang, Gui-Ming Wang, Hong-Ying Zhou, Shi-Lei Wen
Article Number: 1213
Published online on: 24 August 2021

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Heme oxygenase‑1 alleviates advanced glycation end product‑induced oxidative stress, inflammatory response and biological behavioral disorders in rat dermal fibroblasts

Qingling Li, Shangyan Liang, Qianwei Lai, Lishan Shen, Yong Zhang, Ruomi Guo
Article Number: 1212
Published online on: 24 August 2021

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HBxAg promotes HBV replication and EGFR activation in human placental trophoblasts

Yayun Lin, Yan Liu, Dongping Xu, Fanfan Guo, Wentao Zhang, Yidan Zhang, Guiqin Bai
Article Number: 1211
Published online on: 24 August 2021

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Linc8986 and linc0597 in plasma are novel biomarkers for systemic lupus erythematosus

Chunli Rong, Huafeng Xu, Changxin Yan, Feng Wei, Haizhou Zhou, Xiuru Guan
Article Number: 1210
Published online on: 24 August 2021

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Downregulation of microRNA‑96‑5p protects TM3 cells against zearalenone toxicity via targeting ATG9A

Xiaoyuan Xu, Xiaohua Xu, Yanluan Zheng, Lan Xu
Article Number: 1209
Published online on: 24 August 2021

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hsa‑miR‑15b‑5p regulates the proliferation and apoptosis of human vascular smooth muscle cells by targeting the ACSS2/PTGS2 axis

Shujie Gan, Jieqi Mao, Yuqin Pan, Jingdong Tang, Zhengjun Qiu
Article Number: 1208
Published online on: 24 August 2021

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Article

Overexpression of miR‑133b protects against isoflurane‑induced learning and memory impairment

Yu Zhang, Jinyong Liu, Cuili Xie, Pingping Wu
Article Number: 1207
Published online on: 24 August 2021

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Review

Current research developments of patient‑derived tumour xenograft models (Review)

Zhenyu Yin, Ewetse Paul Maswikiti, Qian Liu, Yuping Bai, Xiaomei Li, Wenbo Qi, Le Liu, Yanling Ma, Hao Chen
Article Number: 1206
Published online on: 24 August 2021

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miR‑28‑3p inhibits prostate cancer cell proliferation, migration and invasion, and promotes apoptosis by targeting ARF6

Jiabin Zhang, Yi Yao, Huizhang Li, Shihua Ye
Article Number: 1205
Published online on: 24 August 2021

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Article

Gain of TPPP as a predictor of progression in patients with bladder cancer

Ying-Hsu Chang, Po-Hung Lin, Chin-Chang Chen, Wen-Hui Weng, Kai-Jie Yu, Chung-Yi Liu, Chin-Hsuan Hsieh, Tzu-Hsuan Chang, I-Hung Shao, Hung-Cheng Kan, Cheng-Keng Chuang, See-Tong Pang
Article Number: 1204
Published online on: 24 August 2021

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Podofilox suppresses gastric cancer cell proliferation by regulating cell cycle arrest and the c‑Myc/ATG10 axis

Juan An, Yan Liu, Shenglan Duo, Xiaoming Ma, Ling An, Yunfei Yan, Dongde Ji, Yupeng Yan, Qiliang Cheng, Zhanhai Su
Article Number: 1203
Published online on: 23 August 2021

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lncRNA LOC339524 inhibits the proliferation of bladder cancer cells by targeting the miR‑875‑5p/COPS7A signaling axis

Xuan He, He Xiao, Rui Yang, Hang Chen, Bin Wang
Article Number: 1202
Published online on: 23 August 2021

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Regulatory role of microRNA‑320 during off‑pump coronary artery bypass grafting with dexmedetomidine adjunct anesthesia

Yan Gao, Xiaolong Zhu, Huidan Yu, Wenlong Wang, Yeming Wang, Fulong Li, Jinliang Teng
Article Number: 1201
Published online on: 23 August 2021

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CXCR4 protects bone marrow‑derived endothelial progenitor cells against hypoxia through the PI3K/Akt signaling pathway

Zheng-Yu Liu, Qiu-Xia Yang, Yan Cao, Hong-Wei Pan, Jing-Jing Rong, Jing Ling, Yi Tang, Jin He, Chang-Lu Wang, Xiang Peng, Qiong-Chao Zou, Le Zhang, Jiao Zheng, Jia Wang, Yu Zhang, Jian-Qiang Peng, Lan-Bing Xiong, Feng Liu, Zi-Hui Ying, Zhao-Fen Zheng, Bai-Ling Zhang
Article Number: 1200
Published online on: 23 August 2021

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Leonurine protects against ulcerative colitis by alleviating inflammation and modulating intestinal microflora in mouse models

Suna Zheng, Tianchi Zhuang, Yajun Tang, Ruihan Wu, Ting Xu, Tian Leng, Yao Wang, Zheng Lin, Minghui Ji
Article Number: 1199
Published online on: 23 August 2021

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Prospective evaluation of remifentanil‑propofol mixture for total intravenous anesthesia: A randomized controlled study

Mefkur Bakan, Tarik Umutoglu, Ufuk Topuz, Emine Yilmaz Guler, Harun Uysal, Erdogan Ozturk
Article Number: 1198
Published online on: 23 August 2021

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Astragaloside IV prevents endothelial dysfunction by improving oxidative stress in streptozotocin‑induced diabetic mouse aortas

Yang Zhang, Xiao-Dong Mao, Ai-Li Cao, Shuang Chu, Zhi-Jun Li, Yun-Man Wang, Wen Peng, Li Wang, Hao Wang
Article Number: 1197
Published online on: 20 August 2021

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Effect of low‑level laser intervention on dermatitis symptoms and cytokine changes in DNCB‑induced atopy mouse model: A randomized controlled trial

You Lim Kim, Hee Sung Lim, Suk Min Lee
Article Number: 1196
Published online on: 20 August 2021

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AREL1 E3 ubiquitin ligase inhibits TNF‑induced necroptosis via the ubiquitination of MTX2

Yongsam Jo, Byeongmo Kim, Deug Y. Shin
Article Number: 1195
Published online on: 20 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑22 inhibits cell growth and metastasis in breast cancer via targeting of SIRT1

Quanqing Zou, Qianli Tang, Yinhua Pan, Xuedi Wang, Xiaofeng Dong, Zhongxiao Liang, Dong Huang
Article Number: 1194
Published online on: 19 August 2021

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January-2026 Volume 31 Issue 1

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Article Open Access

Adiposity indices and bone health amongst Malaysian adults: Evidence from a cross‑sectional study

Wenjian Zhao, Weizheng Zhang, Kok-Yong Chin, Xiaodong Ma, Hashwin Singh Tejpal Singh, Sophia Ogechi Ekeuku, Yuanzhong Wang, Xia Ji, Yang Guo, Sok Kuan Wong, Norliza Muhammad, Teh Rohaila Jamil, Saharuddin Ahmad
Article Number: 28
Published online on: 21 November 2025

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Ginsenoside Re attenuates homocysteine‑induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling

Shaolin Li, Chenge Zhao, Shengqin Yu, Kaijing Yang, Shuying Zhang, Sixu Liu
Article Number: 27
Published online on: 21 November 2025

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Case Report Open Access

Intussusception of the initial jejunum secondary to adenoma in the third and fourth portions of the duodenum: A case report

Lingbo Huo, Lixing Ma
Article Number: 26
Published online on: 21 November 2025

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Correction Open Access

[Corrigendum] Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β‑catenin signaling pathway

Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
Article Number: 25
Published online on: 19 November 2025

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Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

Shengbin Han, Jingzhe Xu, Chenchen Yu, Hongxi Guan, Shun Ding
Article Number: 24
Published online on: 18 November 2025

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[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 23
Published online on: 17 November 2025

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Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

Jinqi Yan, Xiaohu Wang, Chen Liang
Article Number: 22
Published online on: 14 November 2025

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Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

Mingxin He, Feng Chen, Xiaomin Xian, Zhi Guo
Article Number: 21
Published online on: 14 November 2025

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Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

Yunching Lai, Xiaolei Chen, Hebing Zhou
Article Number: 20
Published online on: 10 November 2025

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Case Report Open Access

Diagnostic challenge of aneurysmal dermatofibroma mimicking cutaneous metastasis in a patient with lung cancer: A case report

Jong Yun Choi, Heeyang Park, Jangyoun Choi
Article Number: 19
Published online on: 10 November 2025

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[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Article Number: 18
Published online on: 10 November 2025

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Article

Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study

Jeng-Yuan Yao, De-Tian-Yu Tzeng, Cai-Hong Feng, Gong-Man Xiao, Tian-Ni You, Ru-Yu Zheng
Article Number: 17
Published online on: 06 November 2025

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Case Report Open Access

Chronic maxillary sinusitis masquerading as a maxillary sinus neoplasm: A case report

Ji-Hyeon Oh, Seong-Gon Kim, Su-Young Kim
Article Number: 16
Published online on: 04 November 2025

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[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
Article Number: 15
Published online on: 04 November 2025

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A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

Jingqiao Li, Yipeng Yang, Xu Zhang, Dandan Zhang, Yadong Yu, Rong Chen, Wei Du
Article Number: 14
Published online on: 30 October 2025

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Case Report Open Access

Primary epithelioid angiomatous nodule of the vocal cord: A case report and literature review

Keda Li, Bin Huang, Lubing Cai, Mingqi Huang, Jianping Shi, Mingdi Jin, Ning Qian, Yongkang Guo
Article Number: 13
Published online on: 29 October 2025

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Hepatic perivascular epithelioid cell tumor: A rare mesenchymal tumor with epithelioid features: A case report

Mahmoud Abbas, Benjamin Strücker, Mehmet Haluk Morgül, Andreas Pascher, Wolfgang Hartmann, Eva Wardelmann
Article Number: 12
Published online on: 29 October 2025

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[Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet

Lei Huang, Chao Ding, Xinmin Si
Article Number: 11
Published online on: 29 October 2025

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Article

Evaluation of total oxidant status/total antioxidant capacity and DNA damage in neonates with high lactate levels in umbilical cord blood gases

Burcu Cebeci, Aydemir Yalvaç, Derya Büyükkayhan, Dilek Kurnaz, Hakan Çakir, Murat Elevli
Article Number: 10
Published online on: 29 October 2025

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Case Report

Treatment of a mandibular molar with primary failure of eruption: A case report

Ming Guo, Weisheng Zhang
Article Number: 9
Published online on: 29 October 2025

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Effect of the water‑soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells

Xinghuanyu Xu, Lin Liu, Wenbai Zhang, Pu Xu
Article Number: 8
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

Xiao Ma, Jingjing Ma, Han Zhang, Xiaodong Jia, Tianrui Wang, Shanshan Ma, Yingze Zhang
Article Number: 4
Published online on: 21 October 2025

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Epimedin C: A promising neuroprotective agent that can participate in mediating the JNK/Nrf2/HO‑1 signaling pathway to prevent neurodegenerative diseases

Chao Cong, Xuan-Ling Li, Guang-Yao Lin, Lian-Wei Xu
Article Number: 3
Published online on: 21 October 2025

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Application of pleural effusion cell blocks for immunohistochemistry and EGFR gene mutation testing for advanced lung cancer

Shouxiang Zhao, Yuhong Liu, Tao Wang, Ying Li, Ze Chen, Xiaoshan Cai
Article Number: 2
Published online on: 21 October 2025

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Correction Open Access

[Corrigendum] Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility in vitro

Huan Wang, Tingtao Chen, Yidan Chen, Tao Luo, Buzhen Tan, Houyang Chen, Hongbo Xin
Article Number: 1
Published online on: 16 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Impact Factor: 2.3

Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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