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Review

Neoadjuvant intraperitoneal chemotherapy for advanced stage gastric cancer (Review)

  • Authors:
    • Nicolae Bacalbasa
    • Camelia Diaconu
    • Bogdan Socea
    • Florentina Gherghiceanu
    • Cornel Savu
    • Mihai Dimitriu
    • Irina Balescu
    • Ioan Cordos
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania, Department of Internal Medicine, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania, Department of Surgery, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania, Department of Marketing and Medical Technology, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania, Department of Thoracic Surgery, ‘Marius Nasta’ National Institute of Pneumology, 050159 Bucharest, Romania, Department of Obstetrics and Gynecology, ‘Carol Davila’ University of Medicine and Pharmacy, 020021 Bucharest, Romania, Department of Surgery, ‘Ponderas’ Academic Hospital, 021188 Bucharest, Romania
  • Article Number: 1314
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    Published online on: September 17, 2021
       https://doi.org/10.3892/etm.2021.10749
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Abstract

Gastric cancer remains one of the most lethal malignancies especially when diagnosed in advanced stages of the disease; most often patients diagnosed later during the progression of their disease will present a certain degree of peritoneal contamination such as positive peritoneal cytology or peritoneal metastatic nodules. In such cases most often they then progress to peritoneal carcinomatosis and succumb to the disease within one year. In order to increase the lifespan in such cases multiple therapeutic strategies have been proposed such as radical surgery and intraperitoneal heated chemotherapy or direct intraperitoneal chemotherapy followed by radical surgery. To date, the benefits of intraperitoneal heated chemotherapy at the time of resection have been widely investigated; however the method is still associated with increased rates of perioperative complications. Therefore, attention was focused on investigating the benefits of such procedures as neoadjuvant therapies followed by radical surgery. The aim of the present review was to examine the most efficient therapeutic strategies in advanced‑stage gastric cancer such as neoadjuvant laparoscopic heated intraperitoneal chemotherapy, perioperative heated intraperitoneal chemotherapy and neoadjuvant systemic and peritoneal chemotherapy.
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1 

Parray A, Gupta V, Chaudhari VA, Shrikhande SV and Bhandare MS: Role of intraperitoneal chemotherapy in gastric cancer. Surg Prac Sci. 4(100025)2021.

2 

Thomassen I, van Gestel YR, van Ramshorst B, Luyer MD, Bosscha K, Nienhuijs SW, Lemmens VE and de Hingh IH: Peritoneal carcinomatosis of gastric origin: A population-based study on incidence, survival and risk factors. Int J Cancer. 134:622–628. 2014.PubMed/NCBI View Article : Google Scholar

3 

Yoo CH, Noh SH, Shin DW, Choi SH and Min JS: Recurrence following curative resection for gastric carcinoma. Br J Surg. 87:236–242. 2000.PubMed/NCBI View Article : Google Scholar

4 

Sadeghi B, Arvieux C, Glehen O, Beaujard AC, Rivoire M, Baulieux J, Fontaumard E, Brachet A, Caillot JL, Faure JL, et al: Peritoneal carcinomatosis from non-gynecologic malignancies: Results of the EVOCAPE 1 multicentric prospective study. Cancer. 88:358–363. 2000.PubMed/NCBI View Article : Google Scholar

5 

Boku N: Gastrointestinal Oncology Study Group of Japan Clinical Oncology Group. Chemotherapy for metastatic disease: Review from JCOG trials. Int J Clin Oncol. 13:196–200. 2008.PubMed/NCBI View Article : Google Scholar

6 

Mezhir JJ, Shah MA, Jacks LM, Brennan MF, Coit DG and Strong VE: Positive peritoneal cytology in patients with gastric cancer: Natural history and outcome of 291 patients. Indian J Surg Oncol. 2:16–23. 2011.PubMed/NCBI View Article : Google Scholar

7 

Maeda H, Kobayashi M and Sakamoto J: Evaluation and treatment of malignant ascites secondary to gastric cancer. World J Gastroenterol. 21:10936–10947. 2015.PubMed/NCBI View Article : Google Scholar

8 

Glehen O, Mohamed F and Gilly FN: Peritoneal carcinomatosis from digestive tract cancer: New management by cytoreductive surgery and intraperitoneal chemohyperthermia. Lancet Oncol. 5:219–228. 2004.PubMed/NCBI View Article : Google Scholar

9 

Brenkman HJ, Päeva M, van Hillegersberg R, Ruurda JP and Haj Mohammad N: Pro-phylactic hyperthermic intraperitoneal chemotherapy (HIPEC) for gastric cancer-a systematic review. J Clin Med. 8(1685)2019.PubMed/NCBI View Article : Google Scholar

10 

Desiderio J, Chao J, Melstrom L, Warner S, Tozzi F, Fong Y, Parisi A and Woo Y: The 30-year experience-a meta-analysis of randomised and high-quality non-randomised studies of hyperthermic intraperitoneal chemotherapy in the treatment of gastric cancer. Eur J Cancer. 79:1–14. 2017.PubMed/NCBI View Article : Google Scholar

11 

Blum Murphy M, Ikoma N, Wang X, Estrella J, Roy-Chowdhuri S, Das P, Minsky BD, Song S, Mansfield P, Ajani J and Badgwell B: Phase I trial of hyperthermic intraperitoneal chemoperfusion (HIPEC) with cisplatin, mitomycin, and paclitaxel in patients with gastric adenocarcinoma and associated carcinomatosis or positive cytology. Ann Surg Oncol. 27:2806–2811. 2020.PubMed/NCBI View Article : Google Scholar

12 

Chia CS, You B, Decullier E, Vaudoyer D, Lorimier G, Abboud K, Bereder JM, Arvieux C, Boschetti G and Glehen O: BIG RENAPE Group. Patients with peritoneal carcinomatosis from gastric cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: Is cure a possibility? Ann Surg Oncol. 23:1971–1979. 2016.PubMed/NCBI View Article : Google Scholar

13 

Yonemura Y, Ishibashi H, Hirano M, Mizumoto A, Takeshita K, Noguchi K, Takao N, Ichinose M, Liu Y and Li Y: Effects of neoadjuvant laparoscopic hyperthermic intraperitoneal chemotherapy and neoadjuvant intraperitoneal/systemic chemotherapy on peritoneal metastases from gastric cancer. Ann Surg Oncol. 24:478–485. 2017.PubMed/NCBI View Article : Google Scholar

14 

Ikoma N, Chen HC, Wang X, Blum M, Estrella JS, Fournier K, Mansfield P, Ajani J and Badgwell BD: Patterns of initial recurrence in gastric adenocarcinoma in the era of preoperative therapy. Ann Surg Oncol. 24:2679–2687. 2017.PubMed/NCBI View Article : Google Scholar

15 

Ikoma N, Blum M, Chiang YJ, Estrella JS, Roy-Chowdhuri S, Fournier K, Mansfield P, Ajani J and Badgwell BD: Yield of staging laparoscopy and lavage cytology for radiologically occult peritoneal carcinomatosis of gastric cancer. Ann Surg Oncol. 23:4332–4337. 2016.PubMed/NCBI View Article : Google Scholar

16 

Newhook TE, Agnes A, Blum M, Estrella JS, Das P, Ho L, Ajani JA, Minsky BD, Mansfield P and Badgwell BD: Laparoscopic hyperthermic intraperitoneal chemotherapy is safe for patients with peritoneal metastases from gastric cancer and may lead to gastrectomy. Ann Surg Oncol. 26:1394–1400. 2019.PubMed/NCBI View Article : Google Scholar

17 

Coccolini F, Cotte E, Glehen O, Lotti M, Poiasina E, Catena F, Yonemura Y and Ansaloni L: Intraperitoneal chemotherapy in advanced gastric cancer. Meta-analysis of randomized trials. Eur J Surg Oncol. 40:12–26. 2014.PubMed/NCBI View Article : Google Scholar

18 

Yan TD, Black D, Sugarbaker PH, Zhu J, Yonemura Y, Petrou G and Morris DL: A systematic review and meta-analysis of the randomized controlled trials on adjuvant intraperitoneal chemotherapy for resectable gastric cancer. Ann Surg Oncol. 14:2702–2713. 2007.PubMed/NCBI View Article : Google Scholar

19 

Yang XJ, Huang CQ, Suo T, Mei LJ, Yang GL, Chen FL, Zhou YF, Xiong B, Yonemura Y and Li Y: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy improves survival of patients with peritoneal carcinomatosis from gastric cancer: Final results of a phase III randomized clinical trial. Ann Surg Oncol. 18:1575–1581. 2011.PubMed/NCBI View Article : Google Scholar

20 

Badgwell B: Multimodality therapy of localized gastric adenocarcinoma. J Natl Compr Canc Netw. 14:1321–1327. 2016.PubMed/NCBI View Article : Google Scholar

21 

Sugarbaker PH: Gastric cancer: Prevention and treatment of peritoneal metastases. J Cancer Metastasis Treat. 4(7)2018.

22 

Yu P, Ye Z, Dai G, Zhang Y, Huang L, Du Y and Cheng X: Neoadjuvant systemic and hyperthermic intraperitoneal chemotherapy combined with cytoreductive surgery for gastric cancer patients with limited peritoneal metastasis: A prospective cohort study. BMC Cancer. 20(1108)2020.PubMed/NCBI View Article : Google Scholar

23 

Beeharry MK, Zhang TQ, Liu WT and Gang ZZ: Optimization of perioperative approaches for advanced and late stages of gastric cancer: Clinical proposal based on literature evidence, personal experience, and ongoing trials and research. World J Surg Oncol. 18(51)2020.PubMed/NCBI View Article : Google Scholar

24 

Beeharry MK, Ni ZT, Yang ZY, Zheng YN, Feng RH, Liu WT, Yan C, Yao XX, Li C, Yan M and Zhu ZG: Study protocol of a multicenter phase III randomized controlled trial investigating the efficiency of the combination of neoadjuvant chemotherapy (NAC) and neoadjuvant laparoscopic intraperitoneal hyperthermic chemotherapy (NLHIPEC) followed by R0 gastrectomy with intraoperative HIPEC for advanced gastric cancer (AGC): Dragon II trial. BMC Cancer. 20(224)2020.PubMed/NCBI View Article : Google Scholar

25 

Badgwell B, Blum M, Das P, Estrella J, Wang X, Ho L, Fournier K, Royal R, Mansfield P and Ajani J: Phase II trial of laparoscopic hyperthermic intraperitoneal chemoperfusion for peritoneal carcinomatosis or positive peritoneal cytology in patients with gastric adenocarcinoma. Ann Surg Oncol. 24:3338–3344. 2017.PubMed/NCBI View Article : Google Scholar

26 

Sarela AI, Miner TJ, Karpeh MS, Coit DG, Jaques DP and Brennan MF: Clinical outcomes with laparoscopic stage M1, unresected gastric adenocarcinoma. Ann Surg. 243:189–195. 2006.PubMed/NCBI View Article : Google Scholar

27 

Brenner H, Rothenbacher D and Arndt V: Epidemiology of stomach cancer. Methods Mol Biol. 472:467–477. 2009.PubMed/NCBI View Article : Google Scholar

28 

Cappellani A, Zanghi A, Di Vita M, Zanet E, Veroux P, Cacopardo B, Cavallaro A, Piccolo G, Lo Menzo E, Murabito P and Berretta M: Clinical and biological markers in gastric cancer: Update and perspectives. Front Biosci (Schol Ed). 2:403–412. 2010.PubMed/NCBI View Article : Google Scholar

29 

Feingold PL, Kwong ML, Sabesan A, Sorber R and Rudloff U: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for gastric cancer and other less common disease histologies: Is it time? J Gastrointest Oncol. 7:87–98. 2016.PubMed/NCBI View Article : Google Scholar

30 

Wu XJ, Yuan P, Li ZY, Bu ZD, Zhang LH, Wu AW, Zong XL, Li SX, Shan F, Ji X, et al: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy improves the survival of gastric cancer patients with ovarian metastasis and peritoneal dissemination. Tumor Biol. 34:463–469. 2013.PubMed/NCBI View Article : Google Scholar

31 

Yonemura Y, Kawamura T, Bandou E, Takahashi S, Sawai T and Matsuki N: Treatment of peritoneal dissemination from gastric cancer by peritonectomy and chemohyperthermic peritoneal perfusion. Br J Surg. 92:370–375. 2005.PubMed/NCBI View Article : Google Scholar

32 

Takahashi T, Hagiwara A, Shimotsuma M, Sawai T and Yamaguchi T: Prophylaxis and treatment of peritoneal carcinomatosis: Intraperitoneal chemotherapy with mitomycin C bound to activated carbon particles. World J Surg. 19:565–569. 1995.PubMed/NCBI View Article : Google Scholar

33 

Bryan ML, Fitzgerald NC, Levine EA, Shen P, Stewart JH and Votanopoulos KI: Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in sarcomatosis from gastrointestinal stromal tumor. Am Surg. 80:890–895. 2014.PubMed/NCBI

34 

Braeuer F, Fischer I, Brammen L, Pressl G, Fuegger R, Rohregger K and Wundsam H: Outcome in patients treated with cytoreductive surgery and HIPEC for gastric cancer with peritoneal carcinomatosis. Anticancer Res. 40:2151–2156. 2020.PubMed/NCBI View Article : Google Scholar

35 

Bonnot PE, Piessen G, Kepenekian V, Decullier E, Pocard M, Menuier B, Bereder JM, Abboud K, Marchal F, Quenet F, et al: Cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy for gastric cancer with peritoneal metastases (CYTO-CHIP study): A propensity score analysis. J Clin Oncol. 37:2028–2040. 2019.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Bacalbasa N, Diaconu C, Socea B, Gherghiceanu F, Savu C, Dimitriu M, Balescu I and Cordos I: Neoadjuvant intraperitoneal chemotherapy for advanced stage gastric cancer (Review). Exp Ther Med 22: 1314, 2021.
APA
Bacalbasa, N., Diaconu, C., Socea, B., Gherghiceanu, F., Savu, C., Dimitriu, M. ... Cordos, I. (2021). Neoadjuvant intraperitoneal chemotherapy for advanced stage gastric cancer (Review). Experimental and Therapeutic Medicine, 22, 1314. https://doi.org/10.3892/etm.2021.10749
MLA
Bacalbasa, N., Diaconu, C., Socea, B., Gherghiceanu, F., Savu, C., Dimitriu, M., Balescu, I., Cordos, I."Neoadjuvant intraperitoneal chemotherapy for advanced stage gastric cancer (Review)". Experimental and Therapeutic Medicine 22.5 (2021): 1314.
Chicago
Bacalbasa, N., Diaconu, C., Socea, B., Gherghiceanu, F., Savu, C., Dimitriu, M., Balescu, I., Cordos, I."Neoadjuvant intraperitoneal chemotherapy for advanced stage gastric cancer (Review)". Experimental and Therapeutic Medicine 22, no. 5 (2021): 1314. https://doi.org/10.3892/etm.2021.10749
Copy and paste a formatted citation
x
Spandidos Publications style
Bacalbasa N, Diaconu C, Socea B, Gherghiceanu F, Savu C, Dimitriu M, Balescu I and Cordos I: Neoadjuvant intraperitoneal chemotherapy for advanced stage gastric cancer (Review). Exp Ther Med 22: 1314, 2021.
APA
Bacalbasa, N., Diaconu, C., Socea, B., Gherghiceanu, F., Savu, C., Dimitriu, M. ... Cordos, I. (2021). Neoadjuvant intraperitoneal chemotherapy for advanced stage gastric cancer (Review). Experimental and Therapeutic Medicine, 22, 1314. https://doi.org/10.3892/etm.2021.10749
MLA
Bacalbasa, N., Diaconu, C., Socea, B., Gherghiceanu, F., Savu, C., Dimitriu, M., Balescu, I., Cordos, I."Neoadjuvant intraperitoneal chemotherapy for advanced stage gastric cancer (Review)". Experimental and Therapeutic Medicine 22.5 (2021): 1314.
Chicago
Bacalbasa, N., Diaconu, C., Socea, B., Gherghiceanu, F., Savu, C., Dimitriu, M., Balescu, I., Cordos, I."Neoadjuvant intraperitoneal chemotherapy for advanced stage gastric cancer (Review)". Experimental and Therapeutic Medicine 22, no. 5 (2021): 1314. https://doi.org/10.3892/etm.2021.10749
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