|
1
|
Langdahl B, Ferrari S and Dempster DW:
Bone modeling and remodeling: Potential as therapeutic targets for
the treatment of osteoporosis. Ther Adv Musculoskelet Dis.
8:225–235. 2016.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Zhou S, Huang G and Chen G: Synthesis and
biological activities of drugs for the treatment of osteoporosis.
Eur J Med Chem. 197(112313)2020.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Feehan J, Al Saedi A and Duque G:
Targeting fundamental aging mechanisms to treat osteoporosis.
Expert Opin Ther Targets. 23:1031–1039. 2019.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Mendoza FA, Le Roux M and Ahmed I: Primary
osteoporosis in men: An unmet medical need. Fertil Steril.
112:791–798. 2019.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Zhu Y, Huang Z, Wang Y, Xu W, Chen H, Xu
J, Luo S, Zhang Y, Zhao D and Hu J: The efficacy and safety of
denosumab in postmenopausal women with osteoporosis previously
treated with bisphosphonates: A review. J Orthop Translat. 22:7–13.
2020.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Cao DW, Liu MM, Duan R, Tao YF, Zhou JS,
Fang WR, Zhu JR, Niu L and Sun JG: The lncRNA Malat1 functions as a
ceRNA to contribute to berberine-mediated inhibition of HMGB1 by
sponging miR-181c-5p in poststroke inflammation. Acta Pharmacol
Sin. 41:22–33. 2020.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Huynh NP, Anderson BA, Guilak F and
McAlinden A: Emerging roles for long noncoding RNAs in skeletal
biology and disease. Connect Tissue Res. 58:116–141.
2017.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Del Real A, López-Delgado L, Sañudo C,
García-Ibarbia C, Laguna E, Perez-Campo FM, Menéndez G, Alfonso A,
Fakkas M, García-Montesinos B, et al: Long noncoding RNAs as bone
marrow stem cell regulators in osteoporosis. DNA Cell Biol.
39:1691–1699. 2020.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Peng S, Cao L, He S, Zhong Y, Ma H, Zhang
Y and Shuai C: An overview of long noncoding RNAs involved in bone
regeneration from mesenchymal stem cells. Stem Cells Int.
2018(8273648)2018.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Chen X, Yang L, Ge D, Wang W, Yin Z, Yan
J, Cao X, Jiang C, Zheng S and Liang B: Long non-coding RNA XIST
promotes osteoporosis through inhibiting bone marrow mesenchymal
stem cell differentiation. Exp Ther Med. 17:803–811.
2019.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Centofanti F, Santoro M, Marini M,
Visconti VV, Rinaldi AM, Celi M, D'Arcangelo G, Novelli G, Orlandi
G, Tancredi V, et al: Identification of aberrantly-expressed long
non-coding RNAs in osteoblastic cells from osteoporotic patients.
Biomedicines. 8(65)2020.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Ge DW, Wang WW, Chen HT, Yang L and Cao
XJ: Functions of microRNAs in osteoporosis. Eur Rev Med Pharmacol
Sci. 21:4784–4789. 2017.PubMed/NCBI
|
|
13
|
Sun M, Zhou X, Chen L, Huang S, Leung V,
Wu N, Pan H, Zhen W, Lu W and Peng S: The regulatory roles of
MicroRNAs in bone remodeling and perspectives as biomarkers in
osteoporosis. Biomed Res Int. 2016(1652417)2016.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Zhang M, Cheng L and Zhang Y:
Characterization of dysregulated lncRNA-associated ceRNA network
reveals novel lncRNAs with ceRNA activity as epigenetic diagnostic
biomarkers for osteoporosis risk. Front Cell Dev Biol.
8(184)2020.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Zheng C, Bai C, Sun Q, Zhang F, Yu Q, Zhao
X, Kang S, Li J and Jia Y: Long noncoding RNA XIST regulates
osteogenic differentiation of human bone marrow mesenchymal stem
cells by targeting miR-9-5p. Mech Dev. 162(103612)2020.PubMed/NCBI
|
|
16
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Zhang HL, Du XY and Dong QR: LncRNA XIXT
promotes osteogenic differentiation of bone mesenchymal stem cells
and alleviates osteoporosis progression by targeting miRNA-30a-5p.
Eur Rev Med Pharmacol Sci. 23:8721–879. 2019.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Wang K, Wang Y, Hu Z, Zhang L, Li G, Dang
L, Tan Y, Cao X, Shi F, Zhang S and Zhang G: Bone-targeted lncRNA
OGRU alleviates unloading-induced bone loss via miR-320-3p/Hoxa10
axis. Cell Death Dis. 11(382)2020.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Zhang Y, Chen B, Li D, Zhou X and Chen Z:
LncRNA NEAT1/miR-29b-3p/BMP1 axis promotes osteogenic
differentiation in human bone marrow-derived mesenchymal stem
cells. Pathol Res Pract. 215:525–531. 2019.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Zhang Y, Chen XF, Li J, He F, Li X and Guo
Y: lncRNA Neat1 stimulates osteoclastogenesis via sponging miR-7. J
Bone Miner Res. 35:1772–1781. 2020.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Gao Y, Xiao F, Wang C, Wang C, Cui P,
Zhang X and Chen X: Long noncoding RNA MALAT1 promotes osterix
expression to regulate osteogenic differentiation by targeting
miRNA-143 in human bone marrow-derived mesenchymal stem cells. J
Cell Biochem. 119:6986–6996. 2018.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Wang CG, Hu YH, Su SL and Zhong D: LncRNA
DANCR and miR-320a suppressed osteogenic differentiation in
osteoporosis by directly inhibiting the Wnt/β-catenin signaling
pathway. Exp Mol Med. 52:1310–1325. 2020.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Xiang J, Fu HQ, Xu Z, Fan WJ, Liu F and
Chen B: LncRNA SNHG1 attenuates osteogenic differentiation via the
miR-101/DKK1 axis in bone marrow mesenchymal stem cells. Mol Med
Rep. 22:3715–3722. 2020.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Li DJ, Liu GQ and Xu XJ: Silence of lncRNA
BCAR4 alleviates the deterioration of osteoporosis. Eur Rev Med
Pharmacol Sci. 24:5905–5913. 2020.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Wang Y, Wang K, Zhang L, Tan Y, Hu Z, Dang
L, Zhou H, Li G, Wang H, Zhang S, et al: Targeted overexpression of
the long noncoding RNA ODSM can regulate osteoblast function in
vitro and in vivo. Cell Death Dis. 11(133)2020.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Chen Q, Wang M and Wu S: The lncRNA
MCF2L-AS1 controls osteogenic differentiation by regulating
miR-33a. Cell Cycle. 19:1059–1065. 2020.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Yin Q, Wang J, Fu Q, Gu S and Rui Y:
CircRUNX2 through has-miR-203 regulates RUNX2 to prevent
osteoporosis. J Cell Mol Med. 22:6112–6121. 2018.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Wang CG, Liao Z, Xiao H, Liu H, Hu YH,
Liao QD and Zhong D: LncRNA KCNQ1OT1 promoted BMP2 expression to
regulate osteogenic differentiation by sponging miRNA-214. Exp Mol
Pathol. 107:77–84. 2019.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Ji F, Zhu L, Pan J, Shen Z, Yang Z, Wang
J, Bai X, Lin Y and Tao J: hsa_circ_0026827 promotes osteoblast
differentiation of human dental pulp stem cells through the beclin1
and RUNX1 signaling pathways by sponging miR-188-3p. Front Cell Dev
Biol. 8(470)2020.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Campos-Viguri GE, Peralta-Zaragoza O,
Jiménez-Wences H, Longinos-González AE, Castañón-Sánchez CA,
Ramírez-Carrillo M, Camarillo CL, Castañeda-Saucedo E,
Jiménez-López MA, Martínez-Carrillo DN and Fernández-Tilapa G:
MiR-23b-3p reduces the proliferation, migration and invasion of
cervical cancer cell lines via the reduction of c-Met expression.
Sci Rep. 10(3256)2020.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Wang J, Xue H, Zhu Z, Gao J, Zhao M and Ma
Z: Expression of serum exosomal miR-23b-3p in non-small cell lung
cancer and its diagnostic efficacy. Oncol Lett.
20(30)2020.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Jiang K, Teng GD and Chen YQ: MicroRNA-23
suppresses osteogenic differentiation of human bone marrow
mesenchymal stem cells by targeting the MEF2C-mediated MAPK
signaling pathway. J Gene Med. 22(e3216)2020.PubMed/NCBI View
Article : Google Scholar
|
|
33
|
Gao M, Sun L, Xu K, Zhang L, Zhang Y, He
T, Sun R, Huang H, Zhu J, Zhang Y, et al: Association between
low-to-moderate fluoride exposure and bone mineral density in
Chinese adults: Non-negligible role of RUNX2 promoter methylation.
Ecotoxicol Environ Saf. 203(111031)2020.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Kim WJ, Shin HL, Kim BS, Kim HJ and Ryoo
HM: RUNX2-modifying enzymes: Therapeutic targets for bone diseases.
Exp Mol Med. 52:1178–1184. 2020.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Gomathi K, Akshaya N, Srinaath N, Moorthi
A and Selvamurugan N: Regulation of Runx2 by post-translational
modifications in osteoblast differentiation. Life Sci.
245(117389)2020.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Narayanan A, Srinaath N, Rohini M and
Selvamurugan N: Regulation of Runx2 by MicroRNAs in osteoblast
differentiation. Life Sci. 232(116676)2019.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Lu M, Guo S, Hong F, Zhang Y, Yuan L, Ma C
and Ma J: Pax2 is essential for proliferation and osteogenic
differentiation of mouse mesenchymal stem cells via Runx2. Exp Cell
Res. 371:342–352. 2018.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Lee KM, Park KH, Hwang JS, Lee M, Yoon DS,
Ryu HA, Jung HS, Park KW, Kim J, Park SW, et al: Inhibition of
STAT5A promotes osteogenesis by DLX5 regulation. Cell Death Dis.
9(1136)2018.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Li L, Wang H, Chen X, Li X, Wang G, Jie Z,
Zhao X, Sun X, Huang H, Fan S, et al: Oxidative stress-induced
hypermethylation of KLF5 promoter mediated by DNMT3B impairs
osteogenesis by diminishing the interaction with β-catenin.
Antioxid Redox Signal. 35:1–20. 2021.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Peng S, Shi S, Tao G, Li Y, Xiao D, Wang
L, He Q, Cai X and Xiao J: JKAMP inhibits the osteogenic capacity
of adipose-derived stem cells in diabetic osteoporosis by
modulating the Wnt signaling pathway through intragenic DNA
methylation. Stem Cell Res Ther. 12(120)2021.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Chen XF, Zhu DL, Yang M, Hu WX, Duan YY,
Lu BJ, Rong Y, Dong SS, Hao RH, Chen JB, et al: An osteoporosis
risk SNP at 1p36.12 acts as an allele-specific enhancer to modulate
LINC00339 expression via long-range loop formation. Am J Hum Genet.
102:776–793. 2018.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Ni W, Yao S, Zhou Y, Liu Y, Huang P, Zhou
A, Liu J, Che L and Li J: Long noncoding RNA GAS5 inhibits
progression of colorectal cancer by interacting with and triggering
YAP phosphorylation and degradation and is negatively regulated by
the m6A reader YTHDF3. Mol Cancer.
18(143)2019.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Yang JJ, She Q, Yang Y, Tao H and Li J:
DNMT1 controls LncRNA H19/ERK signal pathway in hepatic stellate
cell activation and fibrosis. Toxicol Lett. 295:325–334.
2018.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Shuai Y, Ma Z, Liu W, Yu T, Yan C, Jiang
H, Tian S, Xu T and Shu Y: TEAD4 modulated LncRNA MNX1-AS1
contributes to gastric cancer progression partly through
suppressing BTG2 and activating BCL2. Mol Cancer.
19(6)2020.PubMed/NCBI View Article : Google Scholar
|
