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Review

Evaluation of small airway function and its application in patients with chronic obstructive pulmonary disease (Review)

  • Authors:
    • Yan Li
    • Xin-Yang Li
    • Li-Rong Yuan
    • Hai-Long Wang
    • Min Pang
  • View Affiliations / Copyright

    Affiliations: Department of Pulmonary and Critical Care Medicine, The First Hospital, Shanxi Medical University, Taiyuan, Shanxi 030001, P.R. China, Department of Medical Parasitology, School of Basic Medicine, Basic Medical Science Center, Shanxi Medical University, Jinzhong, Shanxi 030600, P.R. China
  • Article Number: 1386
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    Published online on: September 29, 2021
       https://doi.org/10.3892/etm.2021.10822
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Abstract

Chronic obstructive pulmonary disease (COPD) is a chronic airway inflammatory disease characterized by incomplete reversible airflow limitation. The diagnosis of COPD is mainly based on pulmonary function examination. In recent years, it has been indicated that small airway dysfunction occurs in patients with all stages of COPD, even in high‑risk smoking groups who have not yet met the diagnostic criteria for COPD. Early recognition of small airway dysfunction and early initiation of small airway targeted therapy have become foci of research. In the present review, the methods of evaluating small airway function were summarized and their merits and shortcomings were discussed. Furthermore, the potential of targeted treatment of small airways in patients with COPD was outlined.
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Copy and paste a formatted citation
Spandidos Publications style
Li Y, Li X, Yuan L, Wang H and Pang M: Evaluation of small airway function and its application in patients with chronic obstructive pulmonary disease (Review). Exp Ther Med 22: 1386, 2021.
APA
Li, Y., Li, X., Yuan, L., Wang, H., & Pang, M. (2021). Evaluation of small airway function and its application in patients with chronic obstructive pulmonary disease (Review). Experimental and Therapeutic Medicine, 22, 1386. https://doi.org/10.3892/etm.2021.10822
MLA
Li, Y., Li, X., Yuan, L., Wang, H., Pang, M."Evaluation of small airway function and its application in patients with chronic obstructive pulmonary disease (Review)". Experimental and Therapeutic Medicine 22.6 (2021): 1386.
Chicago
Li, Y., Li, X., Yuan, L., Wang, H., Pang, M."Evaluation of small airway function and its application in patients with chronic obstructive pulmonary disease (Review)". Experimental and Therapeutic Medicine 22, no. 6 (2021): 1386. https://doi.org/10.3892/etm.2021.10822
Copy and paste a formatted citation
x
Spandidos Publications style
Li Y, Li X, Yuan L, Wang H and Pang M: Evaluation of small airway function and its application in patients with chronic obstructive pulmonary disease (Review). Exp Ther Med 22: 1386, 2021.
APA
Li, Y., Li, X., Yuan, L., Wang, H., & Pang, M. (2021). Evaluation of small airway function and its application in patients with chronic obstructive pulmonary disease (Review). Experimental and Therapeutic Medicine, 22, 1386. https://doi.org/10.3892/etm.2021.10822
MLA
Li, Y., Li, X., Yuan, L., Wang, H., Pang, M."Evaluation of small airway function and its application in patients with chronic obstructive pulmonary disease (Review)". Experimental and Therapeutic Medicine 22.6 (2021): 1386.
Chicago
Li, Y., Li, X., Yuan, L., Wang, H., Pang, M."Evaluation of small airway function and its application in patients with chronic obstructive pulmonary disease (Review)". Experimental and Therapeutic Medicine 22, no. 6 (2021): 1386. https://doi.org/10.3892/etm.2021.10822
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