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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2021 Volume 22 Issue 6

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Impact Factor: 2.3

Article

Demographic, anthropometric, and metabolic characteristics of obstructive sleep apnea patients from Romania before the COVID‑19 pandemic

Adriana Neagos, Daniela Vrinceanu, Mihai Dumitru, Adrian Costache, Romica Cergan
Article Number: 1487
Published online on: 26 October 2021

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Article

Effects of hydroxyapatite extract on rats with transient ischemia: Long‑term potentiation and axon regeneration

Jing Xu, Chunyang Wang, Pengjuan Xu
Article Number: 1486
Published online on: 26 October 2021

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Article

Testicular injury during SARS‑CoV‑2 infection may be neglected: An assessment from scRNA‑seq profiling and protein detection of angiotensin‑converting enzyme II

Tonghui Cai, Guanquan Mao, Rui Zheng, Mao Fang, Xiaorong Yang, Lijing Wang, Cuiling Qi
Article Number: 1485
Published online on: 26 October 2021

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Article Open Access

Epigenetic regulation mechanism of DNA methylation and miRNAs on the expression of the ALOX5AP gene in patients with ischemic stroke

Xiaoshuai Bie, Huiling Zhao, Zhaojing Zhang, Xiaoou Wang, Yingying Luan, Yuanli Wang, Shangdong Yang, Liyan Xu, Xuran Zhang, Baixue Zhou, Hui Dong, Yan Xu, Dongzhi Yang, Hong Zheng, Ying He
Article Number: 1484
Published online on: 26 October 2021

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Article Open Access

Environmental allergens house dust mite‑induced asthma is associated with ferroptosis in the lungs

Weifeng Tang, Ming Dong, Fangzhou Teng, Jie Cui, Xueyi Zhu, Wenqian Wang, Tulake Wuniqiemu, Jingjing Qin, La Yi, Shiyuan Wang, Jingcheng Dong, Ying Wei
Article Number: 1483
Published online on: 26 October 2021

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Article

Prognostic value of the location of submucosal uterine leiomyomas in infertility

George-Alexandru Roșu, Crîngu Antoniu Ionescu, Florin Daniel Călin, Mihai Dimitriu, Liana Pleș, Alexandra Matei, Dan-Bogdan Navolan
Article Number: 1482
Published online on: 25 October 2021

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Review Open Access

Epigenetic approaches for cervical neoplasia screening (Review)

Adrian Albulescu, Adriana Plesa, Alina Fudulu, Iulia Virginia Iancu, Gabriela Anton, Anca Botezatu
Article Number: 1481
Published online on: 25 October 2021

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Article Open Access

Heat‑induced antigen retrieval in fluorescence in situ hybridization: An effective approach enhancing signal intensity in poor‑quality FFPE sections

Qiuxiao Yu, Chi Zhang, Wenting Huang, Li Li
Article Number: 1480
Published online on: 25 October 2021

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Review Open Access

Perspectives on the diagnostic, predictive and prognostic markers of neuroendocrine neoplasms (Review)

Oana Alexandra Ciobanu, Sorina Martin, Simona Fica
Article Number: 1479
Published online on: 25 October 2021

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Article

Reduced miR‑519d‑3p levels in the synovium and synovial fluid facilitate the progression of post‑traumatic osteoarthritis by targeting VEGF

Jianlong Gao, Silong Xia
Article Number: 1478
Published online on: 25 October 2021

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Article Open Access

Regulatory role of miRNA‑23a in diabetic retinopathy

Lihui Sun, Xuezheng Liu, Zhongfu Zuo
Article Number: 1477
Published online on: 25 October 2021

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Article Open Access

Honokiol inhibits endoplasmic reticulum stress‑associated lipopolysaccharide-induced inflammation and apoptosis in bovine endometrial epithelial cells

Wenshu Chen, Jieli Wu, Sisi Zhan, Xiaojie Lu
Article Number: 1476
Published online on: 22 October 2021

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Article Open Access

Shikonin regulates autophagy via the AMPK/mTOR pathway and reduces apoptosis of human umbilical cord mesenchymal stem cells to improve survival in tissues surrounding brain contusion

Xiaohong Zhu, Lijie Huang, Ke Wu, Zhezhe Sun, Kankai Wang, Junnan Ru, Qichuan Zhuge, Linhui Ruan
Article Number: 1475
Published online on: 22 October 2021

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Article Open Access

LPS‑induced inflammatory response and apoptosis are mediated by Fra‑1 upregulation and binding to YKL‑40 in A549 cells

Fei Wang, Wenxuan Li, Zhen Liu, Ronghua Yu, Dalian Wang
Article Number: 1474
Published online on: 22 October 2021

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Article Open Access

Tea polyphenols alleviate hydrogen peroxide‑induced oxidative stress damage through the Mst/Nrf2 axis and the Keap1/Nrf2/HO‑1 pathway in murine RAW264.7 cells

Qian Li, Zhaoyan Qiu, Yan Wang, Chunyan Guo, Xu Cai, Yandong Zhang, Li Liu, Hongkun Xue, Jintian Tang
Article Number: 1473
Published online on: 22 October 2021

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Article Open Access

Anagliptin alleviates lipopolysaccharide‑induced inflammation, apoptosis and endothelial dysfunction of lung microvascular endothelial cells

Jingli Zhang, Lixia Liu
Article Number: 1472
Published online on: 22 October 2021

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Review Open Access

New perspectives on the roles of circular RNAs in osteoarthritis development and progression (Review)

Guoding Cao, Yuqi Pei, Peng Li, Peng Liu, Yapeng Deng, Yu Gao, Jun Liu, Xusheng Li
Article Number: 1471
Published online on: 21 October 2021

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Article

Quantitative proteomic analysis comparing grades ICRS1 and ICRS3 in patients with osteoarthritis

Dong-Sik Chae, Mi Eun Kim, Kyung-Yil Kang, Nae Yoon Lee, Woo-Suk Lee, Jun Sik Lee
Article Number: 1470
Published online on: 21 October 2021

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Article Open Access

miR‑199b‑5p mediates adriamycin‑induced podocyte apoptosis by inhibiting the expression of RGS10

Gaoting Qu, Tiantian He, Aisuo Dai, Yajie Zhao, Dian Guan, Shanwen Li, Huimin Shi, Weihua Gan, Aiqing Zhang
Article Number: 1469
Published online on: 21 October 2021

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Article Open Access

Identification of potential novel biomarkers for abdominal aortic aneurysm based on comprehensive analysis of circRNA‑miRNA‑mRNA networks

Tan Li, Tianlong Wang, Lirong Yan, Chunyan Ma
Article Number: 1468
Published online on: 21 October 2021

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Article Open Access

CircRNA expression profiling of PBMCs from patients with hepatocellular carcinoma by RNA‑sequencing

Zhiyi Han, Wenxing Feng, Rui Hu, Qinyu Ge, Xinfeng Sun, Wenfeng Ma, Wei Zhang, Shaomin Xu, Bolin Zhan, Lai Zhang, Qun Li, Xiaozhou Zhou
Article Number: 1467
Published online on: 20 October 2021

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Article

Ursolic acid ameliorates adipose tissue insulin resistance in aged rats via activating the Akt‑glucose transporter 4 signaling pathway and inhibiting inflammation

Tong-Zhuang Wang, Guo-Wei Zuo, Ling Yao, Chun-Lin Yuan, Hai-Fei Li, Ying Lai, Zhi-Wei Chen, Jun Zhang, Ya-Qian Jin, Johji Yamahara, Jian-Wei Wang
Article Number: 1466
Published online on: 20 October 2021

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Article Open Access

miR‑4486 reverses cisplatin‑resistance of colon cancer cells via targeting ATG7 to inhibiting autophagy

Weiwei Wang, Linxia Chen, Wenjin Zhu, Xianjin Huang, Lin Lin, Zhenhao Quan, Kaiyu Sun, Qingwen Xu
Article Number: 1465
Published online on: 20 October 2021

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Article Open Access

Application of thrombolysis in myocardial infarction risk index in the prediction of long‑term outcomes for patients with ST‑elevation myocardial infarction and multiple vessel disease: A single‑center prospective observational cohort study

Xuefang Fan, Mingliang Li, Jie Cao, Zeming Liang
Article Number: 1464
Published online on: 20 October 2021

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Review Open Access

Mechanism and prevention strategy of a bidirectional relationship between heart failure and cancer (Review)

He Cai, Hongbo Men, Pengyu Cao, Yang Zheng
Article Number: 1463
Published online on: 20 October 2021

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Review Open Access

Transient receptor potential ankyrin 1 and calcium: Interactions and association with disease (Review)

Fangyan Hu, Xiaohua Song, Dingxin Long
Article Number: 1462
Published online on: 20 October 2021

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Article Open Access

Vicenin 3 ameliorates ECM degradation by regulating the MAPK pathway in SW1353 chondrocytes

Yue-Yuan Chen, Xiao-Jie Yan, Xiao-Hua Jiang, Feng-Lai Lu, Xue-Rong Yang, Dian-Peng Li
Article Number: 1461
Published online on: 20 October 2021

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Article Open Access

Comprehensive analysis of mRNAs, lncRNAs and circRNAs in the early phase of microglial activation

Jiagen Wen, Yujie Liu, Zhen Zhan, Shiqing Chen, Bingfeng Hu, Jinfang Ge, Qiliang Xie
Article Number: 1460
Published online on: 20 October 2021

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Article Open Access

Specificity protein 1‑activated bone marrow stromal cell antigen 2 accelerates pancreatic cancer cell proliferation and migration

Chun Lei, Yafeng Hou, Jiong Chen
Article Number: 1459
Published online on: 20 October 2021

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Article Open Access

Downregulation of microRNA-185 expression in diabetic patients increases the expression of NOS2 and results in vascular injury

Yanyan Zhao, Liyan Guo, Jiajia Tian, Huafu Wang
Article Number: 1458
Published online on: 19 October 2021

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Article Open Access

Electroacupuncture regulates inflammation, collagen deposition and macrophage function in skeletal muscle through the TGF‑β1/Smad3/p38/ERK1/2 pathway

Hong Han, Ming Li, Huilin Liu, Haohan Li
Article Number: 1457
Published online on: 19 October 2021

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Case Report Open Access

Clinical, histological and therapeutical aspects in the management of uterine and extrauterine stromal sarcomas: Case reports

Laura Florentina Rebegea, Dorel Firescu, Rodica Marcela Anghel, Laurentia  Gales, Ana Maria Ilie, Mihaela Emilia Dumitru, Mihaela Craescu, Elena Niculet, Alin Laurentiu Tatu, Mariana Stuparu Cretu, Mihaela Lungu, Anca Iulia Neagu
Article Number: 1456
Published online on: 18 October 2021

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Case Report

Pancreatoduodenectomy for groove pancreatitis: A case report and literature review

Nicolae Bacalbasa, Irina Balescu, Simona Dima, Irinel Popescu
Article Number: 1455
Published online on: 18 October 2021

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Article

5‑Aminolevulinic acid combined with ferrous iron improves glucose tolerance in high‑fat diet‑fed mice via upregulation of glucose transporter 1

Yasushi Kuroda, Atsuko Kamiya, Takuya Ishii, Masahiro Ishizuka, Yoko Yamashita, Hitoshi Ashida
Article Number: 1454
Published online on: 15 October 2021

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Article Open Access

MicroRNA‑424 alleviates neurocyte injury by targeting PDCD4 in a cellular model of cerebral ischemic stroke

Hou-Wei Ren, Bin Gu, Yue-Zhan Zhang, Ting Guo, Qian Wang, Yue-Qin Shen, Jun Wang
Article Number: 1453
Published online on: 15 October 2021

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Case Report Open Access

Exacerbation of bronchiectasis by Pseudomonas putida complicating COVID‑19 disease: A case report

Vasiliki Epameinondas Georgakopoulou, Pantelis Avramopoulos, Petros Papalexis, Aikaterini Bitsani, Christos Damaskos, Anna Garmpi, Aikaterini Gkoufa, Nikolaos Garmpis, Konstantinos Mantzouranis, Serafeim Chlapoutakis, Pagona Sklapani, Nikolaos Trakas, Demetrios A. Spandidos
Article Number: 1452
Published online on: 15 October 2021

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Article Open Access

Dynamic observation of 5‑fluorouracil‑induced myocardial injury and mitochondrial autophagy in aging rats

Yuanyang Li, Yufan Zhang, Xiangzhong Zhou, Xianghong Lei, Xinhang Li, Liping Wei
Article Number: 1451
Published online on: 14 October 2021

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Article Open Access

Emergence of blaTEM, blaCTX‑M, blaSHV and blaOXA genes in multidrug‑resistant Enterobacteriaceae and Acinetobacter baumannii in Saudi Arabia

Mutasim E. Ibrahim, Tarig B. Algak, Mohammed Abbas, Bahaeldin K. Elamin
Article Number: 1450
Published online on: 14 October 2021

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Article Open Access

The effectiveness of alprostadil in treating coronary microcirculation dysfunction following ST‑segment elevation myocardial infarction in a pig model

Tianbing Duan, Jinxia Zhang, Ranran Kong, Rui Song, Weilong Huang, Dingcheng Xiang
Article Number: 1449
Published online on: 14 October 2021

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Retraction Open Access

[Retracted] miR-663b promotes tumor cell proliferation, migration and invasion in nasopharyngeal carcinoma through targeting TUSC2

Shaoqiang Liang, Ning Zhang, Yanming Deng, Lusi Chen, Yang Zhang, Zhenhe Zheng, Weijun Luo, Zhiqian Lv, Shaoen Li, Tao Xu
Article Number: 1448
Published online on: 14 October 2021

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Article

Identification and functional annotation of differentially expressed long noncoding RNAs in retinoblastoma

Xiaofen Feng, Jian Gong, Qian Li, Chao Xing, Jiandong Pan, Ruitao Zou, Liya Zheng, Feng Chen
Article Number: 1447
Published online on: 14 October 2021

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Article Open Access

Huoxue Qianyang Qutan recipe attenuates Ang II‑induced cardiomyocyte hypertrophy by regulating reactive oxygen species production

Mingtai Gui, Lei Yao, Bo Lu, Jing Wang, Xunjie Zhou, Jianhua Li, Zhenhua Dong, Deyu Fu
Article Number: 1446
Published online on: 14 October 2021

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Review

Recent advances on polaprezinc for medical use (Review)

Mingru Li, Zhen Sun, Hong Zhang, Zhaoyang Liu
Article Number: 1445
Published online on: 14 October 2021

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Review

Overactive bladder: A review and update

Ioan Scarneciu, Sorin Lupu, Ovidiu Gabriel Bratu, Andreea Teodorescu, Laurian Stefan Maxim, Adrian Brinza, Alexandru Georgian Laculiceanu, Ruxandra Maria Rotaru, Aura-Mihaela Lupu, Camelia Cornelia Scarneciu
Article Number: 1444
Published online on: 14 October 2021

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Article Open Access

Protective effects of flavonoids from the leaves of Carya cathayensis Sarg. against H2O2‑induced oxidative damage and apoptosis in vitro

Fang-Mei Zhou, Jing-Jing Huang, Xu-Jiao Hu, Jingwei Wang, Bing-Qi Zhu, Zhi-Shan Ding, Shigao Huang, Jing-Jing Fang
Article Number: 1443
Published online on: 13 October 2021

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Article Open Access

Repeated exposure to sevoflurane in neonatal rats impairs cognition in adulthood via the PKA‑CREB‑BDNF signaling pathway

Jili Zhao, Jinyu Ren, Shuang Liu, Yanan Gong, Ping Meng, Haitao Tan, Yonggang Chen
Article Number: 1442
Published online on: 13 October 2021

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Article Open Access

Semaphorin 7A knockdown improves injury and prevents endothelial‑to‑mesenchymal transition in ox‑LDL‑induced HUVECs by regulating β1 integrin expression

Xiaoying Song, Jing Meng, Guoliang Yan, Haihui Wang, Haitao Li, Danfei Lou
Article Number: 1441
Published online on: 13 October 2021

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Article Open Access

Low‑doses of aspirin promote the growth of human PC‑9 lung cancer cells through activation of the MAPK family

Yue Qian, Hongliang Dai, Hongyu Li
Article Number: 1440
Published online on: 12 October 2021

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Article

lncRNA RP11‑531A24.3 inhibits the migration and proliferation of vascular smooth muscle cells by downregulating ANXA2 expression

Yilin Wu, Fen Cai, Yuanbin Lu, Yanwei Hu, Qian Wang
Article Number: 1439
Published online on: 12 October 2021

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Article Open Access

Low‑activity 125I implantation into VX2 tumor rabbits and quantitative evaluation of the precise therapeutic effect

Zheng Wang, Juan Wang, Yongyi Yao, Feng Wang, Qiang Fan, Ruifeng Zhao
Article Number: 1438
Published online on: 12 October 2021

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Article Open Access

Diagnostic value of using exosome‑derived cysteine‑rich protein 61 as biomarkers for acute coronary syndrome

Wei Li, Yi Li, Wei Zhi, Chen Liu, Weize Fan, Qing Miao, Xinshun Gu
Article Number: 1437
Published online on: 12 October 2021

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Article Open Access

MicroRNA-98-5p inhibits human mesangial cell proliferation and TNF-α and IL‑6 secretion by targeting BTB and CNC homology 1

Yong Du, Xiaoqiang Shi, Jing Li, Yanhui Jia
Article Number: 1436
Published online on: 12 October 2021

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Article

Isosinensetin alleviates the injury of human bronchial epithelial cells induced by PM2.5

Yang Zou, Shuzhen Li, Xinming Li, Ye Sun, Mingyue Ma, Han Tian, Nan Wang, Jianhui Yuan, Chunling Xiao
Article Number: 1435
Published online on: 11 October 2021

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Article Open Access

Kidney injury molecule‑1 levels are associated with therapeutic outcomes and renal tubulointerstitial injury severity in idiopathic membranous nephropathy

Yidan Zhang, Chunhong Xiang, Liying Gong, Yuanyuan Zhang, Junhui Zhen, Zhao Hu, Xiaoyan Xiao
Article Number: 1434
Published online on: 11 October 2021

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Article Open Access

Irisin attenuates inflammation in a mouse model of ulcerative colitis by altering the intestinal microbiota

Lu Xin Huangfu, Xin Tong Cai, Jing Nan Yang, Hui Chao Wang, Yu Xia Li, Zhi Feng Dai, Rui Lin Yang, Xu Hong Lin
Article Number: 1433
Published online on: 11 October 2021

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Article Open Access

Mechanism underlying circularRNA_014301‑mediated regulation of neuronal cell inflammation and apoptosis

Xiankuan Xie, Yuxiang Xiao, Kan Xu
Article Number: 1432
Published online on: 11 October 2021

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Article

Influence of extracellular nanovesicles derived from adipose‑derived stem cells on nucleus pulposus cell from patients with intervertebral disc degeneration

Zhiqiang Zhang, Liang Zhang, Jiandong Yang, Jijun Huang, Jun Cai, Shengfei Zhang, Xinmin Feng, Qiang Wang
Article Number: 1431
Published online on: 11 October 2021

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Article Open Access

MicroRNA-506-3p targets SIRT1 and suppresses AMPK pathway activation to promote hepatic steatosis Corrigendum in /10.3892/etm.2022.11390

Liang-Kai Hu, Jian-Qing Chen, Hao Zheng, Yuan-Ping Tao, Yuan Yang, Xuan-Fu Xu
Article Number: 1430
Published online on: 11 October 2021

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Review Open Access

Management of psoriasis in children (Review)

Daciana Elena Branisteanu, Simona Georgescu, Ionela Lacramioara Serban, Alin Constantin Pinzariu, Daniel Boda, Minela Aida Maranduca, Mihai Glod, Catalina Ioana Branisteanu, Roxana Bilibau, Andreea  Dimitriu, Alin Codrut Nicolescu, Daniel Constantin Branisteanu
Article Number: 1429
Published online on: 11 October 2021

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Review Open Access

Uveal melanoma diagnosis and current treatment options (Review)

Daniel Constantin Branisteanu, Camelia Margareta Bogdanici, Daciana Elena Branisteanu, Minela Aida Maranduca, Mihail Zemba, Florian Balta, Catalina Ioana Branisteanu, Andreea Dana Moraru
Article Number: 1428
Published online on: 11 October 2021

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Article Open Access

Postpartum assessment of fetal inflammatory response syndrome in a preterm population with premature rupture of membranes: A Romanian study

Gabriela Corina Zaharie, Tudor Drugan, Carmen Crivii, Daniel Muresan, Alexandru Zaharie, Monica Gabriela Hășmășanu, Flaviu Zaharie, Melinda Matyas
Article Number: 1427
Published online on: 11 October 2021

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MicroRNA‑216a‑5p in lipopolysaccharide‑induced endothelial injury

Wenxun Liu, Wenhua Xi, Yan Li, Kerong Hai, Xiaohong Zhou, Yun Wang, Qingshan Ye
Article Number: 1426
Published online on: 11 October 2021

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miR‑142‑5p regulates lipopolysaccharide‑induced bovine epithelial cell proliferation and apoptosis via targeting BAG5

Jinye Lu, Beibei Gu, Wei Lu, Jing Liu, Jiang Lu
Article Number: 1425
Published online on: 11 October 2021

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Use of optical coherence tomography in orthodontics

Stelian-Mihai-Sever Petrescu, Mihaela Jana Țuculină, Eugen  Osiac, Adrian Camen, Alex Ioan Sălan, Felicia Ileana Mărășescu, Andreea Gabriela Nicola, Edwin Sever Bechir, Ionela Teodora Dascălu
Article Number: 1424
Published online on: 11 October 2021

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Pueratin improves diminished ovarian reserve by inhibiting apoptosis

Quan Qi, Xiqian Zhang, Li Yao, Ye Chen, Huinan Weng
Article Number: 1423
Published online on: 11 October 2021

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MicroRNA‑106a‑5p promotes the proliferation, autophagy and migration of lung adenocarcinoma cells by targeting LKB1/AMPK Retraction in /10.3892/etm.2024.12603

Yushan Zhou, Yuxuan Zhang, Yanli Li, Liqiong Liu, Zhidong Li, Yanhong Liu, Yi Xiao
Article Number: 1422
Published online on: 11 October 2021

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Comparative study on the biological characteristics of menstrual blood‑ and endometrium‑derived endometrial cells

Lei Zhao, Meng Ji, Zhifang Chen, Lin Yuan, Yan Ding
Article Number: 1421
Published online on: 11 October 2021

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Efficiency of Gymnema sylvestre‑derived gymnemic acid on the restoration and improvement of brain vascular characteristics in diabetic rats

Nichawadee Sandech, Rawipa Jangchart, Manaras Komolkriengkrai, Piyakorn Boonyoung, Wipapan Khimmaktong
Article Number: 1420
Published online on: 11 October 2021

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Adipose‑derived mesenchymal stem cell exosomes inhibit transforming growth factor‑β1‑induced collagen synthesis in oral mucosal fibroblasts

Junjie Liu, Fuxingzi Li, Binjie Liu, Zhigang Yao, Long Li, Gui Liu, Lei Peng, Yuxin Wang, Junhui Huang
Article Number: 1419
Published online on: 11 October 2021

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Low‑dose aspirin might alleviate the symptoms of preeclampsia by increasing the expression of antioxidative enzymes

Wen Xiong, Yanjun Wang, Xine Zhou
Article Number: 1418
Published online on: 11 October 2021

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Rare case of metachronous tumor: Nasopharyngeal and colorectal carcinoma

Daniela Jicman (Stan), Elena Niculet, Mihaela Lungu, Cristian Onisor, Laura Rebegea, Carmen Bobeica, Alina Mihaela Elisei, Lucretia Anghel, Alin Laurentiu Tatu
Article Number: 1417
Published online on: 08 October 2021

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Prenatal diagnosis of a nonsense mutation in the L1CAM gene resulting in congenital hydrocephalus: A case report and literature review

Rongyue Wang, Hua Chen, Xiaona Wang, Shiyuan Huang, Ailan Xie, Xinmei Wu
Article Number: 1416
Published online on: 08 October 2021

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Adipose mesenchymal stem cells and gingival mesenchymal stem cells have a comparable effect in endothelium repair

Ke Yang, Dongmei Xie, Wanwen Lin, Peng Xiang, Chaoquan Peng
Article Number: 1415
Published online on: 08 October 2021

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Aligned nanofiber nerve conduits inhibit alpha smooth muscle actin expression and collagen proliferation by suppressing TGF‑β1/SMAD signaling in traumatic neuromas

Chenglun Yao, Xijie Zhou, Weidong Weng, Keshav Poonit, Chao Sun, Hede Yan
Article Number: 1414
Published online on: 08 October 2021

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Article

Effects of methylprednisolone and treadmill training on spinal cord injury in experimental rats

Jian-Tao Liu, Shuo-Yu Wang, Han-Ping Xiao, Bing Gu, Hua-Nan Li
Article Number: 1413
Published online on: 08 October 2021

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Article

Use of platelet‑rich plasma in the treatment of infertility in poor responders in assisted human reproduction procedures

Irina Pacu, Nikolaos Zygouropoulos, Mihai Dimitriu, George Rosu, Cringu A. Ionescu
Article Number: 1412
Published online on: 07 October 2021

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Article

High glucose induces HSP47 expression and promotes the secretion of inflammatory factors through the IRE1α/XBP1/HIF‑1α pathway in retinal Müller cells

Xincheng Sun, Chen Chen, Hu Liu, Shaowen Tang
Article Number: 1411
Published online on: 07 October 2021

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β‑naphthoflavone‑induced upregulation of CYP1B1 expression is mediated by the preferential binding of aryl hydrocarbon receptor to unmethylated xenobiotic responsive elements

Toshitaka Miura, Ryo Onodera, Jun Terashima, Shogo Ozawa, Wataru Habano
Article Number: 1410
Published online on: 06 October 2021

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Retraction Open Access

[Retracted] MicroRNA‑503 suppresses cell proliferation and invasion in osteosarcoma via targeting insulin‑like growth factor 1 receptor

Zili Wang, Chenhuang Zheng, Kunqi Jiang, Jinshen He, Xu Cao, Song Wu
Article Number: 1409
Published online on: 06 October 2021

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Glioblastoma pharmacotherapy: A multifaceted perspective of conventional and emerging treatments (Review)

Ani-Simona Sevastre, Alexandra Costachi, Ligia Gabriela Tataranu, Corina Brandusa, Stefan Alexandru Artene, Olivian Stovicek, Oana Alexandru, Suzana Danoiu, Veronica Sfredel, Anica Dricu
Article Number: 1408
Published online on: 06 October 2021

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Effectiveness of COVID‑19 vaccines and their challenges (Review)

Gabriella Marfe, Stefania Perna, Arvind Kumar Shukla
Article Number: 1407
Published online on: 05 October 2021

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Whole‑exome sequencing identifies an RS1 variant in a Chinese family with X‑linked retinoschisis

Doudou Chen, Siquan Zhu
Article Number: 1406
Published online on: 05 October 2021

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Article

Immunomodulatory effects of Radix isatidis polysaccharides in vitro and in vivo

Wei Tao, Ting Fu, Zhuo-Jing He, Han-Peng Zhou, Yan Hong
Article Number: 1405
Published online on: 04 October 2021

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Overexpression of circAtp9b in ulcerative colitis is induced by lipopolysaccharides and upregulates PTEN to promote the apoptosis of colonic epithelial cells

Fengdong Li, Jinjin Fu, Li Fan, Shuangshuang Lu, Huahui Zhang, Xiaoying Wang, Zhanju Liu
Article Number: 1404
Published online on: 04 October 2021

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[Retracted] MicroRNA‑138 directly targets TNFAIP8 and acts as a tumor suppressor in osteosarcoma

Zheng Zhou, Zhihong Li, Yi Shen, Tao Chen
Article Number: 1403
Published online on: 04 October 2021

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Reduced hepcidin expression enhances iron overload in patients with HbE/β‑thalassemia: Α comparative cross‑sectional study

Hanan Kamel M. Saad, Wan Rohani Wan Taib, Imilia Ismail, Muhammad Farid Johan, Abdullah Saleh Al‑Wajeeh, Hamid Ali Nagi Al‑Jamal
Article Number: 1402
Published online on: 04 October 2021

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DUSP4 alleviates LPS‑induced chondrocyte injury in knee osteoarthritis via the MAPK signaling pathway

Zhengnan Li, Bojie Chen
Article Number: 1401
Published online on: 01 October 2021

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Protective effects of safranal on hypoxia/reoxygenation‑induced injury in H9c2 cardiac myoblasts via the PI3K/AKT/GSK3β signaling pathway

Hefei Wang, Bin Zheng, Kaimeng Che, Xue Han, Li Li, Hongfang Wang, Yanshuang Liu, Jing Shi, Shijiang Sun
Article Number: 1400
Published online on: 01 October 2021

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Downregulation of inhibitor of apoptosis protein induces apoptosis and suppresses stemness maintenance in testicular teratoma

Gang Li, Man Liao, Shuang Li, Jia You, Jun Wang, Wei Lei, Chunlei Yang, Haolun Xu, He Xiao, Haitao Chen
Article Number: 1399
Published online on: 01 October 2021

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Roflumilast, a type of phosphodiesterase 4 inhibitor, can reduce intestinal injury caused by sepsis

Zhongyuan Zhang, Meifeng Liang, Xiongfei Wan
Article Number: 1398
Published online on: 01 October 2021

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Heparin alleviates LPS‑induced endothelial injury by regulating the TLR4/MyD88 signaling pathway

Wenxun Liu, Yan Li, Zhaozhao Wu, Kerong Hai, Yun Wang, Xiaohong Zhou, Qingshan Ye
Article Number: 1397
Published online on: 01 October 2021

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Diagnostic value and significance of serum miR‑132 combined with miR‑223 for sepsis‑induced cardiomyopathy

Yanping Li, Bin Lu, Muming Yu, Jianhua Zhai, Ying Yao, Yanfen Chai
Article Number: 1396
Published online on: 01 October 2021

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Article

Tat‑thioredoxin 1 reduces inflammation by inhibiting pro‑inflammatory cytokines and modulating MAPK signaling

Eun Ji Yeo, Min Jea Shin, Hyeon Ji Yeo, Yeon Joo Choi, Eun Jeong Sohn, Lee Re Lee, Hyun Jung Kwon, Hyun Ju Cha, Sung Ho Lee, Sunghou Lee, Yeon Hee Yu, Duk-Soo Kim, Dae Won Kim, Jinseu Park, Kyu Hyung Han, Won Sik Eum, Soo Young Choi
Article Number: 1395
Published online on: 01 October 2021

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Animal models of dry eye disease: Useful, varied and evolving (Review)

Wei Huang, Konstantinos Tourmouzis, Henry Perry, Robert A. Honkanen, Basil Rigas
Article Number: 1394
Published online on: 01 October 2021

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Article

Zinc status, insulin resistance and glycoxidative stress in elderly subjects with type 2 diabetes mellitus

Daniela Grădinaru, Denisa Margină, Anca Ungurianu, Georgiana Nițulescu, Cătălina Monica Pena, Constantin Ionescu‑Tîrgoviște, Rucsandra Dănciulescu Miulescu
Article Number: 1393
Published online on: 30 September 2021

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Melatonin attenuates low shear stress‑induced pyroptosis and endothelial cell dysfunction via the RORα/miR‑223/STAT‑3 signalling pathway

Sui Yi, Yang Yang
Article Number: 1392
Published online on: 30 September 2021

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Activated protein C overexpression suppresses the pyroptosis of subarachnoid hemorrhage model cells by regulating the NLRP3 inflammasome pathway

Ai Yan, Xuyan Pan, Xianqiang Wen, Xiaohu Nie, Yuntao Li
Article Number: 1391
Published online on: 30 September 2021

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Monensin suppresses cell proliferation and invasion in ovarian cancer by enhancing MEK1 SUMOylation

Shujuan Yao, Wen Wang, Bin Zhou, Xiujuan Cui, Hui Yang, Shiqian Zhang
Article Number: 1390
Published online on: 30 September 2021

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DDX3X deficiency alleviates LPS‑induced H9c2 cardiomyocytes pyroptosis by suppressing activation of NLRP3 inflammasome

Dandan Feng, Liang Guo, Jing Liu, Yunxuan Song, Xiuyuan Ma, Haiyang Hu, Ju Liu, Enkui Hao
Article Number: 1389
Published online on: 30 September 2021

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Upregulation of AQP2 mediated by transcription factor FOXO1 inhibits TGF‑β‑induced fibrosis in human urothelial cells

Yue Qiu, Zhaoquan Xing, Zhaoxin Guo, Zhaoxu Liu
Article Number: 1388
Published online on: 30 September 2021

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Review

Peutz‑Jeghers syndrome: Skin manifestations and endocrine anomalies (Review)

Florica Sandru, Aida Petca, Mihai Cristian Dumitrascu, Razvan-Cosmin Petca, Mara Carsote
Article Number: 1387
Published online on: 29 September 2021

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Review

Evaluation of small airway function and its application in patients with chronic obstructive pulmonary disease (Review)

Yan Li, Xin-Yang Li, Li-Rong Yuan, Hai-Long Wang, Min Pang
Article Number: 1386
Published online on: 29 September 2021

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Clinical and surgical algorithm for managing iatrogenic bile duct injuries during laparoscopic cholecystectomy: A multicenter study

Cosmin Moldovan, Daniel Cochior, Gabriel Gorecki, Elena Rusu, Florin-Dan Ungureanu
Article Number: 1385
Published online on: 29 September 2021

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Experimental EDX analysis of different periodontal splinting systems

Ancuța Goriuc, Alexandra Jităreanu, Ioana Mârțu, Cristina Gena Dascălu, Diana Cristala Kappenberg‑Niţescu, Sorina-Mihaela Solomon, Alexandra Mârțu, Liliana Foia, Iustin Țapu, Bogdan Istrate, Monica Tatarciuc, Ionuț Luchian
Article Number: 1384
Published online on: 29 September 2021

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miR‑124 promotes apoptosis and inhibits the proliferation of vessel endothelial cells through P38/MAPK and PI3K/AKT pathways, making it a potential mechanism of vessel endothelial injury in acute myocardial infarction

Weimin Ma, Xin Zhang, Yang Liu
Article Number: 1383
Published online on: 29 September 2021

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NEDD4 E3 ubiquitin protein ligase serves an important role in cutaneous melanoma occurrence and development

Fang Cheng, Yi Cheng, Xiaoling Zhao, Lihui An, Linfang Yang, Zihan Li, Lei Zhang, Runzhi He
Article Number: 1382
Published online on: 28 September 2021

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Article

Euphornin L promotes lipid clearance by dual regulation of LDLR and PCSK9

Huihui Li, Jun Li, Xianjing Zhang, Jiaomeng Li, Cong Xi, Wenqiong Wang, Youli Lu, Lijiang Xuan
Article Number: 1381
Published online on: 28 September 2021

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Baicalein pre‑treatment alleviates hepatic ischemia/reperfusion injury in mice by regulating the Nrf2/ARE pathway

Yi Zhou, Zhi Tan, Hao Huang, Yonglian Zeng, Shilian Chen, Jie Wei, Guozhen Huang, Chaosi Qian, Guandou Yuan, Songqing He
Article Number: 1380
Published online on: 28 September 2021

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Osteoporosis therapies and their mechanisms of action (Review)

Beomchang Kim, Yong Jin Cho, Wonbong Lim
Article Number: 1379
Published online on: 28 September 2021

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Article

Right‑sided colon cancer with invasion of the duodenum or pancreas: A glimpse into our experience

Nadejda Cojocari, Gabriel Viorel Crihana, Nicolae Bacalbasa, Irina Balescu, Leonard David
Article Number: 1378
Published online on: 28 September 2021

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Case Report

Infra-hepatic caval resection en bloc with right nephrectomy followed by caval reconstruction for locally advanced caval leiomyosarcoma: A case report and literature review

Vladislav Brasoveanu, Ion Barbu, Irina Balescu, Nicolae Bacalbasa, Ioan Cordos
Article Number: 1377
Published online on: 28 September 2021

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Probiotics and prebiotics in atopic dermatitis: Pros and cons (Review)

Ionut Serban Fanfaret, Daniel Boda, Laura Mihaela Ion, Daniela Hosseyni, Poliana Leru, Selda Ali, Sabina Corcea, Roxana Bumbacea
Article Number: 1376
Published online on: 28 September 2021

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Whole‑exome sequencing identification of a recurrent CRYBB2 variant in a four‑generation Chinese family with congenital nuclear cataracts

Doudou Chen, Siquan Zhu
Article Number: 1375
Published online on: 28 September 2021

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Ecto‑5'‑nucleotidase (CD73) inhibits dorsal root ganglion neuronal apoptosis by promoting the Ado/cAMP/PKA/CREB pathway

Minghao Shao, Chaojun Zheng, Xiaosheng Ma, Feizhou Lyu
Article Number: 1374
Published online on: 28 September 2021

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MicroRNA‑602 prevents the development of inflammatory bowel diseases in a microbiota‑dependent manner

Song Zhao, Lei Zhu, Wan Feng, Lu Zhang, Dan-Dan Chen, Yu-Cui Hu, Hong Shen
Article Number: 1373
Published online on: 28 September 2021

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Protein tyrosine kinase 7‑knockdown inhibits oral squamous cell carcinoma cell viability, proliferation, migration and invasion via downregulating dishevelled segment polarity protein 3 expression

Xiaoye Jin, Tao Huang, Caihong Ma, Jiafeng Duan, Rong Li, Wei Zhang, Wenyan Tian
Article Number: 1372
Published online on: 28 September 2021

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Article

The Alberta Stroke Program Early CT score (ASPECTS): A predictor of mortality in acute ischemic stroke

Nicolae Ovidiu Pop, Delia Mirela Tit, Camelia Cristina Diaconu, Mihai Alexandru Munteanu, Emilia Elena Babes, Manuela Stoicescu, Mircea Ioachim Popescu, Simona Bungau
Article Number: 1371
Published online on: 27 September 2021

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Case Report

A rare complication of uterine leiomyomata: Severe haemoperitoneum caused by the rupture of an overlying subserosa variceal vein: A case report

Razvan Popovici, Anda Pristavu, Dan-Constantin Andronic, Paula Zan, Benedicte Riey, Murarasu Mara, Raluca Mogos, Loredana Maria Himiniuc, Mihaela Grigore
Article Number: 1370
Published online on: 27 September 2021

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Cutaneous sarcoidosis of the scalp unmasking systemic involvement: A case report

Daniel Boda, Ana Cutoiu, Nona Bejenariu, Constantin Caruntu
Article Number: 1369
Published online on: 27 September 2021

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Ding's herbal enema treats dextran sulfate sodium‑induced colitis in mice by regulating the gut microbiota and maintaining the Treg/Th17 cell balance

Yan-Yan Tan, Yang Ding, Xueping Zheng, Gong-Jian Dai, Su-Min Zhang, Xu Yang, Da-Chao Xu, Peng Chen, Jia-Ming Zhang, Jia-Ze Ma, Meng Li, Shi-Cai Huang, Yan Liu, Yu-Ting Zhang, Han Xing, Kang Ding, Yi-Jiang Ding
Article Number: 1368
Published online on: 27 September 2021

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Receptor‑selective interleukin‑4 mutein attenuates laser‑induced choroidal neovascularization through the regulation of macrophage polarization in mice

Limo Gao, Wenmin Jiang, Haiying Liu, Zhiheng Chen, Yanhui Lin
Article Number: 1367
Published online on: 27 September 2021

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Expression and role of interleukin‑1β and associated biomarkers in deep vein thrombosis

Rouzimaimaiti Zila Pai, Qingbo Fang, Guanglei Tian, Bing Zhu, Xiaohu Ge
Article Number: 1366
Published online on: 27 September 2021

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MicroRNA‑361 reduces the viability and migratory ability of pancreatic cancer cells via mediation of the MAPK/JNK pathway

Juan Wang, Zongjing Xie, Yan Liu, Weiguo Zhang, Tingting Ji
Article Number: 1365
Published online on: 27 September 2021

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Article

LGR6 promotes glioblastoma malignancy and chemoresistance by activating the Akt signaling pathway

Yuan Yuan Cheng, Xue Yang, Xin Gao, Si Xin Song, Ming Feng Yang, Fang Min Xie
Article Number: 1364
Published online on: 27 September 2021

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Comparative analysis of 0.1% cyclosporin A cationic emulsion and 0.05% cyclosporin A emulsion in murine dry eye cases with different severities

Rujun Jin, Ying Li, Lan Li, Jonghwa Kim, Hyeon Jeong Yoon, Kyung Chul Yoon
Article Number: 1363
Published online on: 27 September 2021

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Differentially expressed TUG1 and miR‑145‑5p indicate different severity of chronic heart failure and predict 2‑year survival prognosis

Qinwei Zhu, Shuanghong Li, Kui Ji, Hongyuan Zhou, Chuanchao Luo, Yana Sui
Article Number: 1362
Published online on: 27 September 2021

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Article

DNCP induces the differentiation of induced pluripotent stem cells into odontoblasts by activating the Smad/p‑Smad and p38/p‑p38 signaling pathways

Zhe Liu, Aiping Zhan, Sumeng Fan, Lan Liao, Wenwei Lian
Article Number: 1361
Published online on: 24 September 2021

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Long non‑coding RNA NEAT1 contributes to lipopolysaccharide‑induced inflammation and apoptosis of human middle ear epithelial cells via regulating the miR‑301b‑3p/TLR4 axis

Zhuohui Liu, Tao Lu, Shumin Liu, Fan Zhang, Jinxiong Yang, Shumin Dai, Biao Ruan, Ruiqing Long
Article Number: 1360
Published online on: 24 September 2021

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Bioinformatic and experimental analyses of key biomarkers in pancreatic cancer

Tianyu Ren, Xiaofei Xue, Xiaogang Wang, Xingtong Zhou, Shengchun Dang
Article Number: 1359
Published online on: 24 September 2021

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CMPK2 accelerates liver ischemia/reperfusion injury via the NLRP3 signaling pathway

Yunhai Luo, Daofeng Zheng, Tong Mou, Junliang Pu, Zuotian Huang, Wei Chen, Yuke Zhang, Zhongjun Wu
Article Number: 1358
Published online on: 24 September 2021

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Review Open Access

Pharmacological effects of Picrasma quassioides (D. Don) Benn for inflammation, cancer and neuroprotection (Review)

Jaihyung Lee, Yi-Xi Gong, Hyunjeong Jeong, Hoyoung Seo, Dan-Ping Xie, Hu-Nan Sun, Taeho Kwon
Article Number: 1357
Published online on: 24 September 2021

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Fibroblast growth factor 2 suppresses the expression of C-C motif chemokine 11 through the c-Jun N-terminal kinase pathway in human dental pulp-derived mesenchymal stem cells

Rika Kurogoushi, Tomokazu Hasegawa, Yuki Akazawa, Kokoro Iwata, Asuna Sugimoto, Kimiko Yamaguchi-Ueda, Aya Miyazaki, Anrizandy Narwidina, Keita Kawarabayashi, Takamasa Kitamura, Hiroshi Nakagawa, Tomonori Iwasaki, Tsutomu Iwamoto
Article Number: 1356
Published online on: 24 September 2021

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Non‑alcoholic fatty liver disease and hematologic manifestations (Review)

Vlad Pădureanu, Dalia Dop, Alice Nicoleta Drăgoescu, Rodica Pădureanu, Anca Emanuela Mușetescu, Laurențiu Nedelcu
Article Number: 1355
Published online on: 23 September 2021

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Case Report Open Access

Nevi, biologics for psoriasis and the risk for skin cancer: A real concern? (Case presentation and short review)

Florin Ciprian Bujoreanu, Laura Bezman, Diana Sabina Radaschin, Elena Niculet, Carmen Bobeica, Mihaela Craescu, Thomas Nadasdy, Daniela Stan Jicman, Valeriu Ardeleanu, Lawrence Chukwudi Nwabudike, Silviu Adrian Marinescu, Alin Laurentiu Tatu
Article Number: 1354
Published online on: 23 September 2021

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Effect of inner physical properties on powder adhesion in inhalation capsules in case of a high resistance device

Hiroko Otake, Misa Minami, Mizuki Yamaguchi, Sawako Akiyama, Kazunori Inaba, Noriaki Nagai
Article Number: 1353
Published online on: 23 September 2021

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MicroRNA‑218 aggravates H2O2‑induced damage in PC12 cells via spred2‑mediated autophagy

Duoping Chen, Chunmei Li, Rui Lv
Article Number: 1352
Published online on: 23 September 2021

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Computational healthcare: Present and future perspectives (Review)

Ayumu Asai, Masamitsu Konno, Masateru Taniguchi, Andrea Vecchione, Hideshi Ishii
Article Number: 1351
Published online on: 23 September 2021

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Article

Care of abdominal skin in ankylosing spondylitis patients undergoing corrective spinal surgery

Xiaojing Su, Zheng Wang, Bing Wu, Kai Song, Yixiu Chen, Chunzheng Zhang, Chuanjuan Xue, Lili Ge, Yang Liu
Article Number: 1350
Published online on: 23 September 2021

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Article Open Access

YAP1 promotes high glucose‑induced inflammation and extracellular matrix deposition in glomerular mesangial cells by modulating NF‑κB/JMJD3 pathway

Yan Wang, Jinmei Xu, Zhifeng Cheng
Article Number: 1349
Published online on: 23 September 2021

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Article Open Access

lncRNA ST8SIA6‑AS1 facilitates proliferation and invasion in liver cancer by regulating miR‑142‑3p Retraction in /10.3892/etm.2024.12627

Yang Zhang, Yan Yang, Yi Zhang, Zhisu Liu
Article Number: 1348
Published online on: 23 September 2021

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Adiposity indices and bone health amongst Malaysian adults: Evidence from a cross‑sectional study

Wenjian Zhao, Weizheng Zhang, Kok-Yong Chin, Xiaodong Ma, Hashwin Singh Tejpal Singh, Sophia Ogechi Ekeuku, Yuanzhong Wang, Xia Ji, Yang Guo, Sok Kuan Wong, Norliza Muhammad, Teh Rohaila Jamil, Saharuddin Ahmad
Article Number: 28
Published online on: 21 November 2025

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Ginsenoside Re attenuates homocysteine‑induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling

Shaolin Li, Chenge Zhao, Shengqin Yu, Kaijing Yang, Shuying Zhang, Sixu Liu
Article Number: 27
Published online on: 21 November 2025

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Case Report Open Access

Intussusception of the initial jejunum secondary to adenoma in the third and fourth portions of the duodenum: A case report

Lingbo Huo, Lixing Ma
Article Number: 26
Published online on: 21 November 2025

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Correction Open Access

[Corrigendum] Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β‑catenin signaling pathway

Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
Article Number: 25
Published online on: 19 November 2025

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Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

Shengbin Han, Jingzhe Xu, Chenchen Yu, Hongxi Guan, Shun Ding
Article Number: 24
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 23
Published online on: 17 November 2025

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Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

Jinqi Yan, Xiaohu Wang, Chen Liang
Article Number: 22
Published online on: 14 November 2025

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Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

Mingxin He, Feng Chen, Xiaomin Xian, Zhi Guo
Article Number: 21
Published online on: 14 November 2025

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Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

Yunching Lai, Xiaolei Chen, Hebing Zhou
Article Number: 20
Published online on: 10 November 2025

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Case Report Open Access

Diagnostic challenge of aneurysmal dermatofibroma mimicking cutaneous metastasis in a patient with lung cancer: A case report

Jong Yun Choi, Heeyang Park, Jangyoun Choi
Article Number: 19
Published online on: 10 November 2025

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Retraction Open Access

[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Article Number: 18
Published online on: 10 November 2025

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Article

Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study

Jeng-Yuan Yao, De-Tian-Yu Tzeng, Cai-Hong Feng, Gong-Man Xiao, Tian-Ni You, Ru-Yu Zheng
Article Number: 17
Published online on: 06 November 2025

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Case Report Open Access

Chronic maxillary sinusitis masquerading as a maxillary sinus neoplasm: A case report

Ji-Hyeon Oh, Seong-Gon Kim, Su-Young Kim
Article Number: 16
Published online on: 04 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
Article Number: 15
Published online on: 04 November 2025

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Article Open Access

A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

Jingqiao Li, Yipeng Yang, Xu Zhang, Dandan Zhang, Yadong Yu, Rong Chen, Wei Du
Article Number: 14
Published online on: 30 October 2025

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Case Report Open Access

Primary epithelioid angiomatous nodule of the vocal cord: A case report and literature review

Keda Li, Bin Huang, Lubing Cai, Mingqi Huang, Jianping Shi, Mingdi Jin, Ning Qian, Yongkang Guo
Article Number: 13
Published online on: 29 October 2025

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Case Report Open Access

Hepatic perivascular epithelioid cell tumor: A rare mesenchymal tumor with epithelioid features: A case report

Mahmoud Abbas, Benjamin Strücker, Mehmet Haluk Morgül, Andreas Pascher, Wolfgang Hartmann, Eva Wardelmann
Article Number: 12
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet

Lei Huang, Chao Ding, Xinmin Si
Article Number: 11
Published online on: 29 October 2025

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Article

Evaluation of total oxidant status/total antioxidant capacity and DNA damage in neonates with high lactate levels in umbilical cord blood gases

Burcu Cebeci, Aydemir Yalvaç, Derya Büyükkayhan, Dilek Kurnaz, Hakan Çakir, Murat Elevli
Article Number: 10
Published online on: 29 October 2025

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Case Report

Treatment of a mandibular molar with primary failure of eruption: A case report

Ming Guo, Weisheng Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

Effect of the water‑soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells

Xinghuanyu Xu, Lin Liu, Wenbai Zhang, Pu Xu
Article Number: 8
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Article Open Access

Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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Retraction Open Access

[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

Xiao Ma, Jingjing Ma, Han Zhang, Xiaodong Jia, Tianrui Wang, Shanshan Ma, Yingze Zhang
Article Number: 4
Published online on: 21 October 2025

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Article Open Access

Epimedin C: A promising neuroprotective agent that can participate in mediating the JNK/Nrf2/HO‑1 signaling pathway to prevent neurodegenerative diseases

Chao Cong, Xuan-Ling Li, Guang-Yao Lin, Lian-Wei Xu
Article Number: 3
Published online on: 21 October 2025

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Article Open Access

Application of pleural effusion cell blocks for immunohistochemistry and EGFR gene mutation testing for advanced lung cancer

Shouxiang Zhao, Yuhong Liu, Tao Wang, Ying Li, Ze Chen, Xiaoshan Cai
Article Number: 2
Published online on: 21 October 2025

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Correction Open Access

[Corrigendum] Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility in vitro

Huan Wang, Tingtao Chen, Yidan Chen, Tao Luo, Buzhen Tan, Houyang Chen, Hongbo Xin
Article Number: 1
Published online on: 16 October 2025

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February-2026 Volume 31 Issue 2

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Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Case Report Open Access

Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Case Report

Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Article Open Access

Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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Case Report

A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Article Open Access

Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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Article Open Access

The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Article Open Access

Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Article Open Access

Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Article Open Access

Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Article Open Access

Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Article Open Access

Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Article Open Access

Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Article Open Access

Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Article Open Access

Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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