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Effects of long‑term soft contact lens wear on corneal epithelial thickness after small incision lenticule extraction

  • Authors:
    • Yun Wang
    • Xiaofeng Zhang
    • Xiaolong Yang
    • Yue Xu
    • Baogen Luo
    • Yifeng Qian
  • View Affiliations / Copyright

    Affiliations: Department of Ophthalmology, Suzhou Dushu Lake Hospital (Dushu Lake Hospital Affiliated Soochow University, Medical Center of Soochow University), Suzhou, Jiangsu 215100, P.R. China, Department of Ophthalmology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 8
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    Published online on: October 28, 2021
       https://doi.org/10.3892/etm.2021.10930
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Abstract

The present study investigated changes in corneal epithelial thickness after small incision lenticule extraction (SMILE) in patients with long‑term preoperative soft contact lens (SCL) wear, the impact of SCL wear on the efficacy of surgical outcomes and the effects of long‑term SCL wear on postoperative corneal aberrations. Patients were assigned to three groups according to the duration of SCL wear: Group A, the non‑SCL‑wearing group; group B, those with SCL wear ≤1 year; and group C, those with SCL wear >1 year. Epithelial thickness was recorded in nine zones by anterior segment optical coherence tomography across a 5‑mm diameter before surgery and at 1 week, and 1, 3 and 6 months post‑surgery. Corneal epithelial thickness and corneal aberrations among the three groups were compared, as well as the effects of changes in corneal epithelial thickness on postoperative visual acuity and manifest refraction. No significant differences were noted with regard to age or preoperative spherical equivalent among groups A (22 eyes), B (17 eyes) and C (18 eyes). Preoperative corneal epithelial thickness in the inferonasal, inferior and inferotemporal zones was thinner in group B compared with that in group A, and corneal epithelial thickness was thinner in all nine zones in group C compared with that in group A (P<0.05). At all follow‑up time points, in the central, nasal, inferonasal, inferior, inferotemporal and temporal areas, the epithelial thickness was thinner in group C compared with that in group A (P<0.05). At 3 months postoperatively, the epithelial thickness was thinner in the inferonasal and inferior sectors in group C compared with that in group B (P<0.05), and at 6 months postoperatively, the epithelial thickness in the inferior region was thinner in group C compared with that in group B (P<0.05). There were no significant differences in visual acuity or manifest refraction among the three groups at all postoperative time points. The total higher‑order aberrations were greater in group C compared with those in group A for all time points (P<0.05) and were greater in group C at 1 and 3 months postoperatively compared with those in group B (P<0.05). The spherical aberrations at 3 and 6 months postoperatively were greater in group C compared with those in group A (P<0.05). The coma aberrations were greater in group C compared with those in groups A and B for all time points (P<0.05). In conclusion, long‑term SCL wear will result in corneal epithelial thinning, which does not impact visual acuity or manifest refraction after SMILE.
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Copy and paste a formatted citation
Spandidos Publications style
Wang Y, Zhang X, Yang X, Xu Y, Luo B and Qian Y: Effects of long‑term soft contact lens wear on corneal epithelial thickness after small incision lenticule extraction. Exp Ther Med 23: 8, 2022.
APA
Wang, Y., Zhang, X., Yang, X., Xu, Y., Luo, B., & Qian, Y. (2022). Effects of long‑term soft contact lens wear on corneal epithelial thickness after small incision lenticule extraction. Experimental and Therapeutic Medicine, 23, 8. https://doi.org/10.3892/etm.2021.10930
MLA
Wang, Y., Zhang, X., Yang, X., Xu, Y., Luo, B., Qian, Y."Effects of long‑term soft contact lens wear on corneal epithelial thickness after small incision lenticule extraction". Experimental and Therapeutic Medicine 23.1 (2022): 8.
Chicago
Wang, Y., Zhang, X., Yang, X., Xu, Y., Luo, B., Qian, Y."Effects of long‑term soft contact lens wear on corneal epithelial thickness after small incision lenticule extraction". Experimental and Therapeutic Medicine 23, no. 1 (2022): 8. https://doi.org/10.3892/etm.2021.10930
Copy and paste a formatted citation
x
Spandidos Publications style
Wang Y, Zhang X, Yang X, Xu Y, Luo B and Qian Y: Effects of long‑term soft contact lens wear on corneal epithelial thickness after small incision lenticule extraction. Exp Ther Med 23: 8, 2022.
APA
Wang, Y., Zhang, X., Yang, X., Xu, Y., Luo, B., & Qian, Y. (2022). Effects of long‑term soft contact lens wear on corneal epithelial thickness after small incision lenticule extraction. Experimental and Therapeutic Medicine, 23, 8. https://doi.org/10.3892/etm.2021.10930
MLA
Wang, Y., Zhang, X., Yang, X., Xu, Y., Luo, B., Qian, Y."Effects of long‑term soft contact lens wear on corneal epithelial thickness after small incision lenticule extraction". Experimental and Therapeutic Medicine 23.1 (2022): 8.
Chicago
Wang, Y., Zhang, X., Yang, X., Xu, Y., Luo, B., Qian, Y."Effects of long‑term soft contact lens wear on corneal epithelial thickness after small incision lenticule extraction". Experimental and Therapeutic Medicine 23, no. 1 (2022): 8. https://doi.org/10.3892/etm.2021.10930
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