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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January-2022 Volume 23 Issue 1

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Impact Factor: 2.3

Article

Feibi decoction‑medicated serum inhibits lipopolysaccharide‑induced inflammation in RAW264.7 cells and BMDMs

Wan Wei, Guodong Li, Zhaoheng Liu, Haojie Yang, Shuo Liu, Xinxin Zou, Yang Jiao
Article Number: 110
Published online on: 02 December 2021

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Article

Long non‑coding RNA GAS6‑AS1 enhances breast cancer cell aggressiveness by functioning as a competing endogenous RNA of microRNA‑215‑5p to enhance SOX9 expression

Xiu-Ping Wu, Zhi-Qiang Xu, Wang-Mei Xie, Yao-Long Lai, Kai He, Yan Jiang, Zhen-Chao Xu, Yi-Na Lin, Yuan-Fu Xie
Article Number: 109
Published online on: 02 December 2021

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Article Open Access

Expression of the microRNA‑30 family in pulmonary arterial hypertension and the role of microRNA‑30d‑5p in the regulation of pulmonary arterial smooth muscle cell toxicity and apoptosis

Fan Hu, Hanmin Liu, Chuan Wang, Hanwen Li, Lina Qiao
Article Number: 108
Published online on: 02 December 2021

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Review Open Access

Suicidality and COVID‑19: Suicidal ideation, suicidal behaviors and completed suicides amidst the COVID‑19 pandemic (Review)

Vasiliki Efstathiou, Maria-Ioanna Stefanou, Nikolaos Siafakas, Michael Makris, Georgios Tsivgoulis, Vassilios Zoumpourlis, Demetrios A. Spandidos, Nikolaos Smyrnis, Emmanouil Rizos
Article Number: 107
Published online on: 02 December 2021

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Article

Short vs. long intramedullary nail systems in trochanteric fractures: A randomized prospective single center study

Șerban Dragosloveanu, Christiana D.M. Dragosloveanu, Dragoș C. Cotor, Cristian I. Stoica
Article Number: 106
Published online on: 01 December 2021

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Article Open Access

Improving flexor tendon gliding by using the combination of carboxymethylcellulose‑polyethylene oxide on murine model

Andreea Mioara Corduneanu‑Luca, Sorin Aurelian Pasca, Camelia Tamas, Dan Cristian Moraru, Bogdan Ciuntu, Cristina Stanescu, Irina Hreniuc‑Jemnoschi, Angela Tecuceanu, Teodor Stamate
Article Number: 105
Published online on: 01 December 2021

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Review

Effect of patella resurfacing on functional outcome and revision rate in primary total knee arthroplasty (Review)

Sorin Radu Fleaca, Cosmin Ioan Mohor, Horatiu Dura, Radu Chicea, Calin Mohor, Adrian Boicean, Mihai Dan Roman
Article Number: 104
Published online on: 01 December 2021

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Article

Diagnosis and evolution of the benign tumor osteochondroma

Iulia Bailescu, Mihai Popescu, Lavinia Raluca Sarafoleanu, Simona Bondari, Corneliu Sabetay, Mihaela Roxana Mitroi, Mihaela-Jana Tuculina, Dana-Maria Albulescu
Article Number: 103
Published online on: 01 December 2021

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Article Open Access

Diagnostic challenges, management, and outcome of infants born to mothers with COVID 19 during the first wave of the pandemic

Gabriela Zaharie, Monica Hasmasanu, Daniel Muresan, Tunde Kovacs, Melinda Matyas
Article Number: 102
Published online on: 01 December 2021

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Article Open Access

Clinical and genomic findings in brain heterotopia: Report of a pediatric patient cohort from Romania

Magdalena Budisteanu, Sorina Mihaela Papuc, Alina Erbescu, Catrinel Iliescu, Maria Dobre, Diana Barca, Oana Tarta‑Arsene, Cristina Motoescu, Alice Dica, Carmen Sandu, Cristina Anghelescu, Dana Craiu, Aurora Arghir
Article Number: 101
Published online on: 01 December 2021

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Review Open Access

Research advances in Dieulafoy's disease of the bronchus (Review)

Xiqian Xing, Jie Liu, Shuanglan Xu, Yishu Deng, Jiao Yang
Article Number: 100
Published online on: 01 December 2021

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Article Open Access

lncRNA HOTAIR mediates OGD/R‑induced cell injury and angiogenesis in a EZH2‑dependent manner

Yunpeng Wang, Jiaoyu Mao, Xiaodong Li, Beibei Wang, Xiaoguang Zhou
Article Number: 99
Published online on: 01 December 2021

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Article Open Access

miR‑130b suppresses the invasion and migration of prostate cancer via inhibiting DLL1 and regulating the PI3K/Akt pathways

Li Jia, Bin Lei, Huaijun Gao, Lin Jia, Dan Luo, Jianjun Han, Bingxin Jia
Article Number: 98
Published online on: 01 December 2021

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Article Open Access

MicroRNA‑141‑3p inhibits the progression of oral squamous cell carcinoma via targeting PBX1 through the JAK2/STAT3 pathway

Mingguo Cao, Kebin Tian, Weifeng Sun, Jun Xu, Yu Tang, Shilian Wu
Article Number: 97
Published online on: 01 December 2021

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Review

Application of pulmonary rehabilitation in patients with pulmonary embolism (Review)

Aiping Yu, Weiping Ding, Wanmi Lin, Juan Cai, Weina Huang
Article Number: 96
Published online on: 01 December 2021

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Correction Open Access

[Corrigendum] Clinical and pathological characteristics of IgG4‑related interstitial lung disease

Xiaoting Lv, Feng Gao, Qicai Liu, Sheng Zhang, Zhihua Huang, Yongping Zhu, Haiyang Zong, Quwen Li, Sanyan Li
Article Number: 95
Published online on: 30 November 2021

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Article Open Access

NLRP3 inflammasome activation in gestational diabetes mellitus placentas is associated with hydrogen sulfide synthetase deficiency

Wei Wu, Qing-Ying Tan, Fang-Fang Xi, Yun Ruan, Jing Wang, Qiong Luo, Xiao-Bing Dou, Tian-Xiao Hu
Article Number: 94
Published online on: 30 November 2021

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Case Report Open Access

Magnetic compression stricturoplasty in patients with severe stricture after simultaneous esophageal atresia and duodenal obstruction repair: A case report

Shiqi Liu, Ying Fang, Yi Lv, Jingru Zhao, Ruixue Luo, Ruogu Luo, Jun Cheng, Hongbin Yang, Anpeng Zhang, Yingchun Shen, Na Jiang
Article Number: 93
Published online on: 30 November 2021

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Article Open Access

A genome‑wide scan to locate regions associated with familial vesicoureteral reflux

Zsuzsa Bartik, Ulla Sillén, Malin Östensson, Susanne Fransson, Anna Djos, Rosmarie Sjöberg, Tommy Martinsson
Article Number: 92
Published online on: 28 November 2021

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Review Open Access

Pathological complete response following cisplatin or carboplatin‑based neoadjuvant chemotherapy for triple‑negative breast cancer: A systematic review and meta‑analysis

Radu Vidra, Adina Nemes, Andreea Vidrean, Sebastian Pintea, Snejeana Tintari, Andrada Deac, Tudor Ciuleanu
Article Number: 91
Published online on: 26 November 2021

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Case Report Open Access

Necrotizing fasciitis of the chest wall: A clinical case report and literature review

Cornel Adrian Petreanu, Traian Constantin, Razvan Iosifescu, Alexandru Gibu, Alexandru Zariosu, Alina Croitoru
Article Number: 90
Published online on: 26 November 2021

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Article Open Access

Genital infection with Ureaplasma urealyticum and its effect on pregnancy

Daniela Roxana Matasariu, Alexandra Ursache, Alina Agache, Cristina Elena Mandici, Vasile Lucian Boiculese, Iuliana Elena Bujor, Dorina Rudisteanu, Irina Dumitrascu, Carmina Mihaiela Schaas
Article Number: 89
Published online on: 26 November 2021

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Review

Primary hyperparathyroidism-related giant parathyroid adenoma (Review)

Adina Ghemigian, Alexandra Ioana Trandafir, Eugenia Petrova, Mara Carsote, Ana Valea, Alexandru Filipescu, Ana-Maria Oproiu, Florica Sandru
Article Number: 88
Published online on: 26 November 2021

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Article Open Access

Role of hsa_circ_0066966 in proliferation and migration of hepatitis B virus‑related liver cancer cells

Yinghua Yuan, Xiaojin Yang, Desheng Xie
Article Number: 87
Published online on: 25 November 2021

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Article Open Access

Herbal medicine AnoSpray suppresses proinflammatory cytokines COX‑2 and RANTES in the management of hemorrhoids, acute anal fissures and perineal wounds

Ashwin Porwal, Gopal C. Kundu, Gajanan Bhagwat, Ramesh Butti
Article Number: 86
Published online on: 25 November 2021

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Article Open Access

Extensive mitochondrial proteome disturbance occurs during the early stages of acute myocardial ischemia

Jie Wang, Jun He, Yucheng Fan, Fangjing Xu, Qian Liu, Ruhua He, Ru Yan
Article Number: 85
Published online on: 25 November 2021

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Article Open Access

Role and mechanism of the Dectin‑1‑mediated Syk/NF‑κB signaling pathway in Talaromyces marneffei infection

Yang Peng, Yan Chen, Jinhong Ma, Wei Zhou, Yangyang Wang, Yuyue Wang, Hui Zheng, Weifeng Shi
Article Number: 84
Published online on: 25 November 2021

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Article

GATA4 regulates osteogenic differentiation by targeting miR‑144‑3p

Tao Qiu, Haotian Li, Tao Lu, Liping Shu, Chao Chen, Chunqing Wang
Article Number: 83
Published online on: 25 November 2021

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Article Open Access

High glucose removes natural anti‑α‑galactoside and anti‑β‑glucoside antibody immune complexes adhering to surface O‑glycoproteins of normal platelets and enhances platelet aggregation

Sreedevi Karthi, Sangeetha Sukumari‑Ramesh, Mandagini Geetha, Padinjaradath Sankunni Appukuttan
Article Number: 82
Published online on: 25 November 2021

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Article Open Access

Purinergic 2X7 receptor is involved in adipogenesis and lipid degradation

Jing Li, Linxia Gong, Qiaolan Xu
Article Number: 81
Published online on: 25 November 2021

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Article Open Access

Identification of potential key genes and functional role of CENPF in osteosarcoma using bioinformatics and experimental analysis

Yihui Ma, Jiaping Guo, Da Li, Xianhua Cai
Article Number: 80
Published online on: 25 November 2021

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Article

Neuroprotective effects of an in vitro BBB permeable phenoxythiophene sulfonamide small molecule in glutamate‑induced oxidative injury

Smritee Pokharel, Nailya S. Gliyazova, Srinivasa R. Dandepally, Alfred L. Williams, Gordon C. Ibeanu
Article Number: 79
Published online on: 25 November 2021

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Article Open Access

Paeonol suppresses lipid formation and promotes lipid degradation in adipocytes

Ji Li, Huan Gu
Article Number: 78
Published online on: 25 November 2021

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Article

Endoscopic assessment of sinonasal mucormycosis with SPIES: The ‘battlefield’ sign

Viorel Zainea, Irina Gabriela Ionita, Silviu Pituru, Cătălina Pietroșanu, Andreea Rusescu, Cristian Dragos Stefanescu, Florentina Gherghiceanu, Florin Anghelina, Dragos Palade, Razvan Hainarosie
Article Number: 77
Published online on: 25 November 2021

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Article Open Access

Therapeutic plasma exchange followed by convalescent plasma transfusion in severe and critically ill COVID‑19 patients: A single centre non‑randomized controlled trial

Alexandru Noris Novacescu, Georgiana Duma, Bettina Buzzi, Luminita Mirela Baditoiu, Ovidiu Bedreag, Marius Papurica, Dorel Sandesc, Teodora Sorescu, Daliborca Vlad, Monica Licker
Article Number: 76
Published online on: 24 November 2021

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Review

Melanoma in patients with Li‑Fraumeni syndrome (Review)

Florica Sandru, Mihai Cristian Dumitrascu, Aida Petca, Mara Carsote, Razvan-Cosmin Petca, Adina Ghemigian
Article Number: 75
Published online on: 24 November 2021

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Review

Aggressive prolactinoma (Review)

Ana Valea, Florica Sandru, Aida Petca, Mihai Cristian Dumitrascu, Mara Carsote, Razvan-Cosmin Petca, Adina Ghemigian
Article Number: 74
Published online on: 24 November 2021

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Article Open Access

Insulin resistance quantified by the value of HOMA‑IR and cardiovascular risk in patients with type 2 diabetes

Ionela Mihaela Vladu, Maria Forțofoiu, Diana Clenciu, Mircea-Cătălin Forțofoiu, Rodica Pădureanu, Lucrețiu Radu, Ștefăniță Tiberiu Țenea Cojan, Patricia Mihaela Rădulescu, Vlad Pădureanu
Article Number: 73
Published online on: 24 November 2021

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Article Open Access

Role of methylene blue in detecting the sentinel lymph node in colorectal cancer: In vivo vs. ex vivo technique

Daniel Staniloaie, Constantin Budin, Danut Vasile, George Iancu, Alexandru Ilco, Daniel Iulian Voiculescu, Alexandra Florina Trandafir, Tarek Ammar, Emel Suliman, Emine Suliman, Dorin Dragoş, Maria-Daniela Tanasescu
Article Number: 72
Published online on: 24 November 2021

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Article Open Access

MicroRNA‑208a‑3p participates in coronary heart disease by regulating the growth of hVSMCs by targeting BTG1

Dong Wang, Caiyun Yan
Article Number: 71
Published online on: 23 November 2021

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Article Open Access

Effects of exercise on the expression of long non‑coding RNAs in the bone of mice with osteoporosis

Jianmin Guo, Yu Yuan, Lingli Zhang, Miao Wang, Xiaoyang Tong, Lifei Liu, Miao Zhang, Hui Li, Xi Chen, Jun Zou
Article Number: 70
Published online on: 23 November 2021

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Article Open Access

Stomatin‑knockdown effectively attenuates sepsis‑induced oxidative stress and inflammation of alveolar epithelial cells by regulating CD36

Kangkang Wu, Li Wang
Article Number: 69
Published online on: 23 November 2021

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Article Open Access

Reducing oxidative stress may be important for treating pirarubicin‑induced cardiotoxicity with schisandrin B

Heng Tang, Junhao Zhao, Rui Feng, Peng Pu, Li Wen
Article Number: 68
Published online on: 23 November 2021

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Review Open Access

Interplay between baroreflex sensitivity, obesity and related cardiometabolic risk factors (Review)

Sofia K. Konstantinidou, Georgia Argyrakopoulou, Nicholas Tentolouris, Vangelis Karalis, Alexander Kokkinos
Article Number: 67
Published online on: 23 November 2021

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Article Open Access

Protective effects of syringic acid on inflammation, apoptosis and intestinal barrier function in Caco‑2 cells following oxygen‑glucose deprivation/reoxygenation‑induced injury

Sini Xiang, Jun Xiao
Article Number: 66
Published online on: 23 November 2021

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Article Open Access

Urinary exosomal vitronectin predicts vesicoureteral reflux in patients with neurogenic bladders and spinal cord injuries

Jue Li, Shiying Cai, Chunxian Zeng, Ling Chen, Chun Zhao, Ying Huang, Wenzhi Cai
Article Number: 65
Published online on: 23 November 2021

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Review

Targeting angiogenesis in myocardial infarction: Novel therapeutics (Review)

Jiejie Li, Yuanyuan Zhao, Wei Zhu
Article Number: 64
Published online on: 22 November 2021

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Article Open Access

MicroRNA‑499a (rs3746444A/G) gene variant and susceptibility to type 2 diabetes‑associated end‑stage renal disease

Manal S. Fawzy, Essam Al Ageeli, Saeed Awad Al‑Qahtani, Baraah T. Abu Alsel, Shahad W. Kattan, Walla Alelwani, Eman A. Toraih
Article Number: 63
Published online on: 22 November 2021

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Article Open Access

PINCH1 knockout aggravates myocardial infarction in mice via mediating the NF‑κB signaling pathway

Xuejun Wang, Jinwen Su, Zhikang Lin, Kangyong Liu, Yu Zhuang
Article Number: 62
Published online on: 22 November 2021

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Article Open Access

LIM mineralization protein‑1 inhibits IL‑1β‑induced human chondrocytes injury by altering the NF‑κB and MAPK/JNK pathways

Dijun Ou, Sheng Liu, Changjun Tong, Hezhong Tan, Yadong Yang, Chunlei He
Article Number: 61
Published online on: 21 November 2021

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Review Open Access

Basal cell carcinoma: Comprehensive clinical and histopathological aspects, novel imaging tools and therapeutic approaches (Review)

Elena Niculet, Mihaela Craescu, Laura Rebegea, Carmen Bobeica, Florentina Nastase, Gabriela Lupasteanu, Daniela Jicman Stan, Valentin Chioncel, Lucretia Anghel, Mihaela Lungu, Alin Laurentiu Tatu
Article Number: 60
Published online on: 18 November 2021

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Article

Influence of anti‑TNF therapy and homocysteine level on carotid intima‑media thickness in rheumatoid arthritis patients

Daniela Anghel, Carmen Adella Sîrbu, Elena-Mădălina Hoinoiu, Oana-Georgiana Petrache, Cristina-Florentina Pleșa, Maria Magdalena Negru, Florentina Ioniţă‑Radu
Article Number: 59
Published online on: 18 November 2021

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Review

Highlighting the advantages and benefits of cementless total knee arthroplasty (Review)

Bogdan Uivaraseanu, Cosmin Mihai Vesa, Delia Mirela Tit, Octavian Maghiar, Teodor Andrei Maghiar, Calin Hozan, Aurelia Cristina Nechifor, Tapan Behl, Felicia Liana Andronie‑Cioara, Jenel Marian Patrascu, Simona Bungau
Article Number: 58
Published online on: 18 November 2021

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Article

Impact of modern personalized treatment of breast cancer on surgical attitude and outcomes

Ciprian Tănăsescu, Dragos Serban, Andrei Moisin, Carmen Popa, Ramona Coca, George Iancu, Mihail Silviu Tudosie, Daniel Ovidiu Costea, Bogdan Socea, Corneliu Tudor, Gabriel Andrei Gangura, Laura Carina Tribus, Gabriel Catalin Smarandache
Article Number: 57
Published online on: 17 November 2021

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Article Open Access

Network pharmacology approach to evaluate the therapeutic effects of mulberry leaf components for obesity

Guidan Wang, Jine Dong
Article Number: 56
Published online on: 17 November 2021

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Article Open Access

Salidroside promotes the osteogenic and odontogenic differentiation of human dental pulp stem cells through the BMP signaling pathway

Xiaoling Wei, Jiayang Li, Hui Liu, Chenguang Niu, Dong Chen
Article Number: 55
Published online on: 17 November 2021

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Article Open Access

High miR‑3609 expression is associated with better prognosis in TNBC based on mining using systematic integrated public sequencing data

Rumeng Ding, Zhenfeng Duan, Meng Yang, Xinru Wang, Duolu Li, Quancheng Kan
Article Number: 54
Published online on: 16 November 2021

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Article Open Access

Paeoniflorin inhibits proliferation and promotes autophagy and apoptosis of sweat gland cells

Yuan Xu, Hong He, Ping Li, Hongwei Liu
Article Number: 53
Published online on: 16 November 2021

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Article Open Access

Gut microbiota relieves inflammation in the substantia nigra of chronic Parkinson's disease by protecting the function of dopamine neurons

Tian Zhang, Tan Wang, Xinxu Chen, Zhenqiang Zhao, Zhibin Chen
Article Number: 52
Published online on: 16 November 2021

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Article Open Access

Identification of potential biomarkers for diagnosis of hepatocellular carcinoma

Xing-Hua Liang, Zheng-Ping Feng, Fo-Qiu Liu, Rong Yan, Liang-Yu Yin, Hao Shen, Hai-Lin Lu
Article Number: 51
Published online on: 15 November 2021

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Review

Bullous pemphigoid: An immune disorder related to aging (Review)

Maria Ludovica Deotto, Alice Spiller, Alvise Sernicola, Mauro Alaibac
Article Number: 50
Published online on: 15 November 2021

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Ginger‑derived compounds exert in vivo and in vitro anti‑asthmatic effects by inhibiting the T‑helper 2 cell‑mediated allergic response

Eungyung Kim, Soyoung Jang, Jun Koo Yi, Hyeonjin Kim, Hong Ju Kwon, Hobin Im, Hai Huang, Haibo Zhang, Na Eun Cho, Yonghun Sung, Sung-Hyun Kim, Yeon Shik Choi, Shengqing Li, Zae Young Ryoo, Myoung Ok Kim
Article Number: 49
Published online on: 15 November 2021

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HIF‑1α mediates the protective effect of plasma extracellular particles induced by remote ischaemic preconditioning on oxidative stress injury in human umbilical vein endothelial cells

Minghua Wen, Feng Hu, Zhijian Gong, Chahua Huang, Xiaoshu Cheng
Article Number: 48
Published online on: 15 November 2021

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In vitro and in vivo effects of AVA4746, a novel competitive antagonist of the ligand binding of VLA‑4, in B‑cell acute lymphoblastic leukemia

Yongsheng Ruan, Hye Na Kim, Heather A. Ogana, Eun Ji Gang, Shuangyue Li, Hsiao-Chuan Liu, Deepa Bhojwani, Alan S. Wayne, Mo Yang, Yong-Mi Kim
Article Number: 47
Published online on: 15 November 2021

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Docosahexaenoic acid supplementation alleviates behavioral memory impairment caused via repeated administration of sevoflurane in aged rats

Ming Tian, Yuxia Wang, Degong Liu, Xiaoling Zhao
Article Number: 46
Published online on: 15 November 2021

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Role of AUF1 in modulating the proliferation, migration and senescence of skin cells

Daojiang Yu, Xiaoqian Li, Zhenyu Wang, Sheng Jiang, Tao Yan, Kai Fang, Yuhong Shi, Zhiqiang Jiang, Shuyu Zhang
Article Number: 45
Published online on: 14 November 2021

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Proteomic analysis of human umbilical cord serum exosomes using mass spectrometry and preliminary study of their biological activities in liver cancer cell lines

Donglie Zhu, Wenhui Li, Cheng Fang, Ruozhe Yin, Mingzuo Jiang, Xing Lv, Yong Chen
Article Number: 44
Published online on: 14 November 2021

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Article

Fasudil prevents neomycin‑induced hair cell damage by inhibiting autophagy through the miR‑489/NDP52 signaling pathway in HEI‑OC1 cells

Wei Li, Yanqiu Zhang, Jifeng Xu, Jincan Chen, Xia Gao
Article Number: 43
Published online on: 12 November 2021

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Protective role of lidocaine against cerebral ischemia‑reperfusion injury: An in vitro study

Xiaoyang Lan, Yumin Xu
Article Number: 42
Published online on: 12 November 2021

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Expression and clinical significance of lncRNA TCL6 in serum of patients with preeclampsia

Hong Wang, Guimei Shen, Mengsi Liu, Linjuan Mao, Hui Mao
Article Number: 41
Published online on: 12 November 2021

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Article

Efficiency of resveratrol in the prevention and treatment of age‑related hearing loss

Togay Muderris, Atiye Seda Yar Sağlam, Döndü Unsal, Selçuk Mülazimoğlu, Ergün Sevil, Handan Kayhan
Article Number: 40
Published online on: 12 November 2021

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Isolated liver trauma: A clinical perspective in a non‑emergency center for liver surgery

Stefan Andrei, Sebastian Isac, Maricica Carstea, Cristina Martac, Lucian Mihalcea, Cristina Buzatu, Dorin Ionescu, Dragos Eugen Georgescu, Gabriela Droc
Article Number: 39
Published online on: 11 November 2021

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Article

Determining whether previous SWL for ureteric stones influences the results of ureteroscopy as the second‑line treatment: A clinical study

Cătălin Pricop, Marius Ivanuta, George Daniel Radavoi, Cristian-Valentin Toma, Alin Cumpanaş, Viorel Jinga, Nicolae Bacalbaşa, Dragoş Puia
Article Number: 38
Published online on: 11 November 2021

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Article

Acute kidney injury in moderate and severe COVID‑19 patients: Report of two university hospitals

Daniela Radulescu, Liliana-Ana Tuta, Cristiana David, Carmen Bogeanu, Simona Daniela Onofrei, Elena Stepan, Elena Cuiban, Andreea Ciofalca, Larisa Florina Feier, Camelia Pana, Magda-Cristina Nutu, Ileana Adela Vacaroiu
Article Number: 37
Published online on: 10 November 2021

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Improving tissue characterization, differentiation and diagnosis in gynecology with the narrow‑band imaging technique: A systematic review

Panagiotis Peitsidis, Nikolaos Vrachnis, Stavros Sifakis, Christos Katsetos, Panagiotis Tsikouras, Nikolaos Antonakopoulos, Evaggelos Alexopoulos, Konstantinos Kalmantis
Article Number: 36
Published online on: 10 November 2021

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Effects and mechanisms of CTRP3 overexpression in secondary brain injury following intracerebral hemorrhage in rats

Yu Wan, Jieqiong Wang, Bo Yang, Conggai Huang, Xiaoqin Tang, Hong Yi, Yun Liu, Shaohua Wang
Article Number: 35
Published online on: 09 November 2021

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Article

Maternal and neonatal outcomes following in vitro fertilization: A cohort study in Romania

Andreea Mădălina Bănică, Simona Daniela Popescu, Simona Vlădăreanu
Article Number: 34
Published online on: 09 November 2021

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Review

Morphological classification and changes in dementia (Review)

Alexandra Tudor, Antonia Ioana Vasile, Simona Corina Trifu, Mihai Bogdan Cristea
Article Number: 33
Published online on: 09 November 2021

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Effects of noni on cellular viability and osteogenic differentiation of gingiva‑derived stem cells demonstrated by RNA sequencing and quantitative PCR

Young-Min Song, Hyun-Jin Lee, Sae-Kyung Min, Yoon-Hee Park, Jae-Kwen Oh, Ji-Youn Kim, Jun-Beom Park
Article Number: 32
Published online on: 08 November 2021

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Case Report

Dysplastic nevus syndrome and pancreatic cancer: A case report

Liliana Gabriela Popa, Calin Giurcaneanu, Cornelia Nitipir, Ana Maria Popa, Cristiana Stoica, Cristina Beiu, Tiberiu Tebeica, Silvius Negoita, Mara Madalina Mihai
Article Number: 31
Published online on: 08 November 2021

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Research on myoma in Northeastern Romania and socio‑medical outcomes

Daniela Roxana Matasariu, Alexandra Ursache, Loredana Himiniuc, Bogdan Toma, Vasile Lucian Boiculese, Mihaela Grigore, Irina Dumitrascu
Article Number: 30
Published online on: 08 November 2021

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Review

Outcomes in revision total knee arthroplasty (Review)

Mihai Dan Roman, Octav Russu, Calin Mohor, Radu Necula, Adrian Boicean, Adrian Todor, Cosmin Mohor, Sorin Radu Fleaca
Article Number: 29
Published online on: 08 November 2021

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MicroRNA‑3148 inhibits glioma by decreasing DCUN1D1 and inhibiting the NF‑kB pathway

Qianghua Xu, Xiao Chen, Bin Chen
Article Number: 28
Published online on: 08 November 2021

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Article

Early diagnosis and management of maternal ureterohydronephrosis during pregnancy

Elena Ciciu, Ana-Maria Paṣatu‑Cornea, Lucian Cristian Petcu, Liliana-Ana Tuţă
Article Number: 27
Published online on: 05 November 2021

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Review Open Access

Current trends in gene therapy for retinal diseases (Review)

Andreea Dana Moraru, Dănuț Costin, Raluca Eugenia Iorga, Mihnea Munteanu, Radu Lucian Moraru, Daniel Constantin Branisteanu
Article Number: 26
Published online on: 05 November 2021

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Correction Open Access

[Corrigendum] MicroRNA‑183 suppresses the vitality, invasion and migration of human osteosarcoma cells by targeting metastasis‑associated protein 1

Xiaoya Sun, Yan Xu, Shanfeng Zhang, Xinjie Li, Yadong Wang, Yan Zhang, Xuefeng Zhao, Yuebai Li, Yisheng Wang
Article Number: 25
Published online on: 04 November 2021

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Article Open Access

Direct effect of RFRP‑3 microinjection into the lateral ventricle on the hypothalamic kisspeptin neurons in ovariectomized estrogen‑primed rats

Luyang Cheng, Songhe Yang, Lina Si, Meng Wei, Sen Guo, Zhihong Chen, Shusong Wang, Yuebing Qiao
Article Number: 24
Published online on: 04 November 2021

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Case Report

Influence of pemphigoid gestationis on pregnancy outcome: A case report and review of the literature

Caliopia Gavril Parfene, Roxana Elena Bohiltea, Bianca Margareta Mihai, Corina Grigoriu, Irina Margaritescu, Aurel Doru Chirita, Corina Aurelia Zugravu, Dimitrie Pelinescu‑Onciul
Article Number: 23
Published online on: 04 November 2021

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Association between ribotype and clinical form of enterocolitis with C. difficile in Western Romania: A 2‑year study

Adelina-Raluca Marinescu, Voichița Lăzureanu, Ruxandra Laza, Virgil Musta, Narcisa Nicolescu, Talida Georgiana Cuț, Cristina Dehelean, Cristian Oancea, Monica Licker
Article Number: 22
Published online on: 03 November 2021

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Cold‑pressed oil from Citrus aurantifolia inhibits the proliferation of vascular smooth muscle cells via regulation of PI3K/MAPK signaling pathways

Byeong-Wook Song, Chang Youn Lee, Jun-Hee Park, Bomi Kim, Seahyoung Lee, Soyeon Lim, Sang Woo Kim, Jung-Won Choi, Misun Kang, Jung Hwa Kang, Sung-Suk Lee, Mi-Jin Park, Hanbyeol Moon, Ki-Chul Hwang, Il-Kwon Kim
Article Number: 21
Published online on: 02 November 2021

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Article Open Access

Lactobacillus plantarum induces innate cytokine responses that potentially provide a protective benefit against COVID‑19: A single‑arm, double‑blind, prospective trial combined with an in vitro cytokine response assay

Yasunari Kageyama, Yasuhiro Nishizaki, Koichi Aida, Katsuyuki Yayama, Tomoka Ebisui, Tetsu Akiyama, Tsutomu Nakamura
Article Number: 20
Published online on: 02 November 2021

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Case Report

Polycythemia vera in pregnancy represents a challenge for a multidisciplinary collaboration: A case report and literature review

Roxana Elena Bohiltea, Emilia Niculescu‑Mizil, Bianca Margareta Mihai, Florentina Furtunescu, Ionita Ducu, Octavian Munteanu, Tiberiu Augustin Georgescu, Corina Grigoriu
Article Number: 19
Published online on: 01 November 2021

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Article Open Access

Screening of potential hub genes in pulmonary thromboembolism

Yan Lu, Jun Dai, Qiyang Liu, Pan Cai, Jianghua Zheng
Article Number: 18
Published online on: 30 October 2021

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Article Open Access

Radiofrequency thermocoagulation for the treatment of trigeminal neuralgia

Zhengming Wang, Zhijia Wang, Kai Li, Xu Su, Chao Du, Yu Tian
Article Number: 17
Published online on: 30 October 2021

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Article Open Access

MicroRNA‑25 promotes cell proliferation, migration and invasion in glioma by directly targeting cell adhesion molecule 2

Gang Peng, Yi Liu, Chenxing Yang, Chenfu Shen
Article Number: 16
Published online on: 30 October 2021

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Case Report Open Access

Cutaneous adverse reactions in a lung cancer patient treated with pembrolizumab: A case report

Carmen Bobeica, Laura Rebegea, Gabriel Murariu, Michaela Dobre, Aurel Nechita, Alin Laurentiu Tatu, Elena Niculet, Lucretia Anghel, Silvia Fotea, Mihaela Craescu
Article Number: 15
Published online on: 29 October 2021

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Perfluorooctane sulfonate induces heart toxicity involving cardiac apoptosis and inflammation in rats

Dongmin Xu, Li Li, Leilei Tang, Ming Guo, Jie Yang
Article Number: 14
Published online on: 28 October 2021

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Correction Open Access

[Corrigendum] MicroRNA-125b-1-3p mediates intervertebral disc degeneration in rats by targeting teashirt zinc finger homeobox 3

Xiaotong Meng, Yue Zhu, Lin Tao, Sichao Zhao, Shui Qiu
Article Number: 13
Published online on: 28 October 2021

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Article Open Access

Long non‑coding RNA H19 mediates N‑acetyltransferase 1 gene methylation in the development of tamoxifen resistance in breast cancer

Hong Sun, Guo Wang, Jiaqin Cai, Xiaoxia Wei, Ying Zeng, Yan Peng, Jie Zhuang
Article Number: 12
Published online on: 28 October 2021

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Article Open Access

Theaflavin‑3,3'‑digallate attenuates cigarette smoke extract‑induced pulmonary emphysema in mice by suppressing necroptosis

Guangxin Luan, Zhen Zhu, Kaiyue Wu, Shaojun Yin
Article Number: 11
Published online on: 28 October 2021

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Review

Survey on COVID‑19‑related mortality associated with occupational infection during the first phase of the pandemic: A systematic review

Paola Senia, Francesca Vella, Nicola Mucci, George Dounias, Antonio Trovato, Andrea Marconi, Caterina Ledda, Venerando Rapisarda, Ermanno Vitale
Article Number: 10
Published online on: 28 October 2021

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Article Open Access

MicroRNA‑367‑3p suppresses sevoflurane‑induced adult rat astrocyte apoptosis by targeting BCL2L11

Deming Xu, Changbi Zhou, Juanyun Lin, Wenhui Cai, Wei Lin
Article Number: 9
Published online on: 28 October 2021

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Article Open Access

Effects of long‑term soft contact lens wear on corneal epithelial thickness after small incision lenticule extraction

Yun Wang, Xiaofeng Zhang, Xiaolong Yang, Yue Xu, Baogen Luo, Yifeng Qian
Article Number: 8
Published online on: 28 October 2021

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Article Open Access

IRF2‑induced Claudin‑7 suppresses cell proliferation, invasion and migration of oral squamous cell carcinoma

Xin Li, Weidong Yang
Article Number: 7
Published online on: 27 October 2021

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Article Open Access

Bioinformatics analysis and experimental validation of differentially expressed genes in mouse articular chondrocytes treated with IL‑1β using microarray data

Fan Liang, Le Peng, Yong-Gang Ma, Wei Hu, Wei-Bing Zhang, Ming Deng, Ya-Ming Li
Article Number: 6
Published online on: 27 October 2021

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Article Open Access

Altered Wnt5a expression affects radiosensitivity of non‑small cell lung cancer via the Wnt/β‑catenin pathway

Junzhe Li, Shijie Xu, Hua Dong, Xiayu Wu, Li-Hong Wang, Xianhua Xu
Article Number: 5
Published online on: 26 October 2021

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Article Open Access

Influence of atherosclerosis on the molecular expression of the TRPC1/BK signal complex in the aortic smooth muscles of mice

Lian-Fa Wang, Dong-Yun Ling, Meng-Xun Huang, Li-Wei Tao, Quan-Xiu Tong, Yong Hou, Hua Li, Zhen Chen, Bang-Zhu Zhang, Hong-Tao Lu, Yun-Fei Wang, Xian-Ge Zhang
Article Number: 4
Published online on: 26 October 2021

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Article Open Access

Hirudin, a thrombin inhibitor, attenuates TGF-β-induced fibrosis in renal proximal tubular epithelial cells by inhibition of protease-activated receptor 1 expression via S1P/S1PR2/S1PR3 signaling

Qiang Lin, Chunli Long, Zhengang Wang, Ronghui Wang, Wei Shi, Jiwei Qiu, Junlin Mo, Yongxiang Xie
Article Number: 3
Published online on: 26 October 2021

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Article Open Access

Porphyromonas gingivalis lipopolysaccharide enhances the proliferation of human periodontal ligament cells via upregulation of cyclin D1, cyclin A and cyclin B1

Jiajing Lu, Yajing Hu, Zhongyuan Tang, Chengfei Zhang, Lijian Jin, Min Gu, Yanqi Yang
Article Number: 2
Published online on: 26 October 2021

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Article Open Access

Long non‑coding RNA profiles in plasma exosomes of patients with gastric high‑grade intraepithelial neoplasia

Feng Hu, Min Rao, Manli Zhang, Qingqing Meng, Minjie Wan, Xiuna Zhang, Lili Ding, Yanfang Jiang
Article Number: 1
Published online on: 26 October 2021

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May-2026 Volume 31 Issue 5

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Review Open Access

FCER1G: A multifunctional regulator in the immune microenvironment (Review)

Yuyu Zhang, Jinglan Wang, Wenting He, Tao Liu
Article Number: 146
Published online on: 26 March 2026

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Article Open Access

A nomogram for predicting recurrence‑free survival in patients with high‑risk GIST receiving adjuvant imatinib: A nationwide registry study

Chun-Nan Yeh, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh, Li-Yaun Bai, Jun-Te Hsu, I-Shu Chen, Li-Tzong Chen, Hui-Jen Tsai, The Taiwan Cooperative Oncology Group Gist Study Group
Article Number: 145
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 144
Published online on: 23 March 2026

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Article

Risk factors for severe retinopathy of prematurity: A retrospective case‑control study

Qingmin Ma, Xi Lv, Jiangya Wang, Kejun Li, Wenwen Τang
Article Number: 143
Published online on: 20 March 2026

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Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial

Dawei Wang, Jingya Dai, Shumei Li, Yaping Liu, Xiaofeng Xing, Lei Huang, Qijun Pang
Article Number: 142
Published online on: 19 March 2026

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Maresin 1 activates autophagy through SIRT1/PPAR‑γ signaling to mitigate high glucose‑induced pyroptosis in human retinal pigment epithelial cells

Jun Zhang, Ding Zhao, Yuanqing Zhang, Haoxiang Sun, Zhipeng Yan, Haiyan Sun
Article Number: 141
Published online on: 19 March 2026

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Review Open Access

Advances in new ultrasound technologies in targeted prostate biopsy (Review)

Tingting Jin, Liying Wang, Shusen Zheng
Article Number: 140
Published online on: 19 March 2026

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Review Open Access

Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review)

Min Liu, Kui Su
Article Number: 139
Published online on: 19 March 2026

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Article Open Access

Immunohistochemical evaluation of gastric‑type markers in primary extramammary Paget disease: Differential MUC5AC expression between in situ and invasive lesions

Naoto Kohno, Mitsuaki Ishida, Shizuka Ono, Yoshinobu Hirose
Article Number: 138
Published online on: 19 March 2026

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Disrupted beginnings: Neurodevelopmental outcomes of COVID‑19 lockdowns in early childhood (Review)

Ioanna Giannopoulou, Vasiliki Efstathiou, Maria-Ioanna Stefanou, Panagiota Korkoliakou, James N. Tsoporis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 137
Published online on: 16 March 2026

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[Retracted] Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF‑κB and PI3K/AKT pathways

Ling Sun, Jing Zhang
Article Number: 136
Published online on: 16 March 2026

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Article Open Access

Effects of fullerenol C60 on the liver, heart and brain tissues of streptozotocin‑induced diabetic rats with sepsis

Necmiye Şengel, Ömer Kubat, Laman Farajsoylu, Ahmet Çağri Büyükkasap, Muharrem Atli, Şaban Cem Sezen, Hasan Bostanci, Kürşat Dikmen, Işin Güneş, Fatma Er, Mustafa Kavutçu, Mustafa Arslan
Article Number: 135
Published online on: 13 March 2026

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Long non‑coding RNA KCNQ1OT1 promotes ovarian cancer cell malignant characteristics by targeting the miR‑140‑5p/KLK10 axis

Renjie Duan, Zhenyu Tao, Shun Tao, Aichen Yang, Xu Yang, Changzheng Li, Xiaoxiang Zhu, Kexin Zhang, Zhuofu Li, Shanjun Tao
Article Number: 134
Published online on: 11 March 2026

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Article

Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
Published online on: 09 March 2026

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Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
Published online on: 09 March 2026

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Case Report Open Access

Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
Published online on: 06 March 2026

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Case Report

Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report

Yajun Yao, Ge-Hong Dong, De-Cai Tian
Article Number: 129
Published online on: 06 March 2026

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Article Open Access

Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta‑analysis

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 128
Published online on: 06 March 2026

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Article

Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Case Report

Management after two consecutive suction losses during small‑incision lenticule extraction: A case report

Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
Published online on: 03 March 2026

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Case Report Open Access

Hematemesis resulting from mesenteric venous thrombosis: A case report

Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
Article Number: 125
Published online on: 02 March 2026

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Article

Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Article

Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
Published online on: 27 February 2026

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Case Report

A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Review Open Access

Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review)

Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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June-2026 Volume 31 Issue 6

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Multi‑omics analysis of glutamine and fish collagen peptides in alleviating post‑antibiotic Streptococcus pneumoniae injury in feline lung cells

Huasong Bai, Tong Liu, Hengyan Wang, Hongchen Jin, Yunliang Li, Zhanzhong Wang
Article Number: 148
Published online on: 30 March 2026

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[Retracted] MicroRNA‑1236‑3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis

Tingting Meng, Shiman Shen, Cheng Li, Xuehua Liu
Article Number: 147
Published online on: 30 March 2026

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