Influence of pemphigoid gestationis on pregnancy outcome: A case report and review of the literature

  • Authors:
    • Caliopia Gavril Parfene
    • Roxana Elena Bohiltea
    • Bianca Margareta Mihai
    • Corina Grigoriu
    • Irina Margaritescu
    • Aurel Doru Chirita
    • Corina Aurelia Zugravu
    • Dimitrie Pelinescu‑Onciul
  • View Affiliations

  • Published online on: November 4, 2021     https://doi.org/10.3892/etm.2021.10945
  • Article Number: 23
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Abstract

Pemphigoid gestationis is considered to be a rare pregnancy exclusive bullous disease, which modifies the course of the pregnancy, with difficulties in the management of the pruritus and skin lesions as well as a possible change in the neonatal outcome. Differential diagnosis of skin lesions and pruritus in pregnancy is challenging, and complementary investigations such as skin biopsy or laboratory tests are indispensable. The correct diagnosis and proper treatment could change the natural course of a pregnancy at risk and could improve maternal and fetal morbidity. We present the case of a patient with pemfigoid gestationis with the aim to highlight: i) the management of this pregnancy‑associated skin disorder which transfers this pregnancy into a category of high obstetrical risk pregnancy; ii) the particularities of the course of the pregnancy; and iii) the importance in the differential diagnosis of pregnancy dermatoses. The particularity of this case of pemphigoid gestationis was the acute fetal distress in the absence of intrauterine growth restriction that is frequently found in this pathology, and the management of a rare pregnancy skin condition that currently has no standard treatment.
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January-2022
Volume 23 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Parfene CG, Bohiltea RE, Mihai BM, Grigoriu C, Margaritescu I, Chirita AD, Zugravu CA and Pelinescu‑Onciul D: Influence of pemphigoid gestationis on pregnancy outcome: A case report and review of the literature. Exp Ther Med 23: 23, 2022
APA
Parfene, C.G., Bohiltea, R.E., Mihai, B.M., Grigoriu, C., Margaritescu, I., Chirita, A.D. ... Pelinescu‑Onciul, D. (2022). Influence of pemphigoid gestationis on pregnancy outcome: A case report and review of the literature. Experimental and Therapeutic Medicine, 23, 23. https://doi.org/10.3892/etm.2021.10945
MLA
Parfene, C. G., Bohiltea, R. E., Mihai, B. M., Grigoriu, C., Margaritescu, I., Chirita, A. D., Zugravu, C. A., Pelinescu‑Onciul, D."Influence of pemphigoid gestationis on pregnancy outcome: A case report and review of the literature". Experimental and Therapeutic Medicine 23.1 (2022): 23.
Chicago
Parfene, C. G., Bohiltea, R. E., Mihai, B. M., Grigoriu, C., Margaritescu, I., Chirita, A. D., Zugravu, C. A., Pelinescu‑Onciul, D."Influence of pemphigoid gestationis on pregnancy outcome: A case report and review of the literature". Experimental and Therapeutic Medicine 23, no. 1 (2022): 23. https://doi.org/10.3892/etm.2021.10945