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Article Open Access

Diagnostic challenges, management, and outcome of infants born to mothers with COVID 19 during the first wave of the pandemic

  • Authors:
    • Gabriela Zaharie
    • Monica Hasmasanu
    • Daniel Muresan
    • Tunde Kovacs
    • Melinda Matyas
  • View Affiliations / Copyright

    Affiliations: Department of Neonatology, ‘Iuliu Hatieganu’ University of Medicine and Pharmacy, 400006 Cluj Napoca, Romania, Department of Obstetrics and Gynecology, ‘Iuliu Hatieganu’ University of Medicine and Pharmacy, 400006 Cluj Napoca, Romania
    Copyright: © Zaharie et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 102
    |
    Published online on: December 1, 2021
       https://doi.org/10.3892/etm.2021.11025
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Abstract

Severe acute respiratory distress syndrome with coronavirus 2 (SARS‑CoV‑2) infection affected pregnant women during the pandemic. Immunological particularity of this population and the increased need for medical assistance placed this population in a high‑risk category for SARS‑Cov‑2 infection. Owing to high contamination risk and limited studies regarding vertical transmission, the labor and delivery of positive women required particular conditions. Cesarean section probably proved to be the optimal option for delivery of infants to reduce the risk of infection during birth. The aim of the present study was to present the management and outcome of infants born to mothers confirmed with coronavirus disease 2019 (COVID 19) prior to delivery. This is a longitudinal, retrospective study, analyzing demographics, laboratory data and management of neonates born to mothers with diagnosis of SARS‑Cov‑2 infection. The results showed that 5 neonates were born to SARS‑Cov‑2‑positive mothers, all by Cesarean section and had a negative reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) test. None of the women breastfed during the hospital stay. The negative RT‑qPCR test allowed us to reduce the hospital stay of infants and care in non‑isolated areas. In summary, in the present study, vertical or perinatal transmission of the infection was not present. The testing of the pregnant women, their isolation and delivery in safe conditions for the medical staff were possible, with the latter using adequate protection equipment to limit their infection and the risk for the newborns.
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Copy and paste a formatted citation
Spandidos Publications style
Zaharie G, Hasmasanu M, Muresan D, Kovacs T and Matyas M: Diagnostic challenges, management, and outcome of infants born to mothers with COVID 19 during the first wave of the pandemic. Exp Ther Med 23: 102, 2022.
APA
Zaharie, G., Hasmasanu, M., Muresan, D., Kovacs, T., & Matyas, M. (2022). Diagnostic challenges, management, and outcome of infants born to mothers with COVID 19 during the first wave of the pandemic. Experimental and Therapeutic Medicine, 23, 102. https://doi.org/10.3892/etm.2021.11025
MLA
Zaharie, G., Hasmasanu, M., Muresan, D., Kovacs, T., Matyas, M."Diagnostic challenges, management, and outcome of infants born to mothers with COVID 19 during the first wave of the pandemic". Experimental and Therapeutic Medicine 23.1 (2022): 102.
Chicago
Zaharie, G., Hasmasanu, M., Muresan, D., Kovacs, T., Matyas, M."Diagnostic challenges, management, and outcome of infants born to mothers with COVID 19 during the first wave of the pandemic". Experimental and Therapeutic Medicine 23, no. 1 (2022): 102. https://doi.org/10.3892/etm.2021.11025
Copy and paste a formatted citation
x
Spandidos Publications style
Zaharie G, Hasmasanu M, Muresan D, Kovacs T and Matyas M: Diagnostic challenges, management, and outcome of infants born to mothers with COVID 19 during the first wave of the pandemic. Exp Ther Med 23: 102, 2022.
APA
Zaharie, G., Hasmasanu, M., Muresan, D., Kovacs, T., & Matyas, M. (2022). Diagnostic challenges, management, and outcome of infants born to mothers with COVID 19 during the first wave of the pandemic. Experimental and Therapeutic Medicine, 23, 102. https://doi.org/10.3892/etm.2021.11025
MLA
Zaharie, G., Hasmasanu, M., Muresan, D., Kovacs, T., Matyas, M."Diagnostic challenges, management, and outcome of infants born to mothers with COVID 19 during the first wave of the pandemic". Experimental and Therapeutic Medicine 23.1 (2022): 102.
Chicago
Zaharie, G., Hasmasanu, M., Muresan, D., Kovacs, T., Matyas, M."Diagnostic challenges, management, and outcome of infants born to mothers with COVID 19 during the first wave of the pandemic". Experimental and Therapeutic Medicine 23, no. 1 (2022): 102. https://doi.org/10.3892/etm.2021.11025
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